Thi Hanh Nguyen Vu, Ngoc Tung Quach, Quynh Anh Pham, Phuong Chi Le, Van The Nguyen, Thi Thanh Xuan Le, Thi Thao Do, Do Hoang Anh, Tran Hong Quang, Hoang Ha Chu, Quyet Tien Phi
UNLABELLED: Endophytic fungi are known as an alternative promising source of anticancer drug, paclitaxel, however fungi inhabiting in medicinal plant Podocarpus pilgeri and their paclitaxel production have not been reported to date. In the present study, a total of 15 culturable fungi classified into 5 genera, were successfully recovered from P. pilgeri collected in Vietnam. Screening fungal dichloromethane extracts for anticancer activity revealed that only PQF9 extract displayed potent inhibitory effects on A549 and MCF7 cancer cell lines with IC50 values of 33...
December 2023: Indian Journal of Microbiology