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Journals Documenta Ophthalmologica. Adv...

Documenta Ophthalmologica. Advances in Ophthalmology

https://read.qxmd.com/read/38871951/s-cone-contribution-to-oscillatory-potentials-in-patients-with-blue-cone-monochromacy
#1
JOURNAL ARTICLE
Giulia Righetti, Melanie Kempf, Susanne Kohl, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Krunoslav Stingl
PURPOSE: The aim of this exploratory study is to investigate the role of S-cones in oscillatory potentials (OPs) generation by individuals with blue-cone monochromacy (BCM), retaining S-cones, and achromatopsia (ACHM), lacking cone functions. METHODS: This retrospective study analyzed data from 39 ACHM patients, 20 BCM patients, and 26 controls. Central foveal thickness was obtained using spectral-domain optical coherence tomography, while amplitude and implicit time (IT) of a- and b-waves were extracted from the ISCEV Standard dark-adapted 3 cd...
June 14, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38825634/vitamin-a-deficiency-retinopathy-in-the-setting-of-celiac-disease-and-liver-fibrosis
#2
JOURNAL ARTICLE
Austin Pereira, Tom Wright, Daniel Weisbrod, Brian G Ballios
PURPOSE: Vitamin A is a lipid-soluble compound that is critical in maintaining phototransduction. Ocular manifestations of hypovitaminosis A may present with anterior segment signs of xeropthalmia, with advanced cases also causing classic retinal and electrophysiologic changes of vitamin A deficiency retinopathy. We present a case of vitamin A deficiency retinopathy, with corresponding retinal imaging and electrophysiology, in an adult patient with celiac disease and liver fibrosis. METHODS: A single case report was conducted in Toronto, Canada...
June 3, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38713327/correction-accelerated-hydroxychloroquine-toxic-retinopathy-response-to-letter
#3
Ayushi Mohapatra, Prasad Gupta, Dhanashree Ratra
No abstract text is available yet for this article.
May 7, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38630375/clinical-course-of-two-siblings-with-potassium-voltage-gated-channel-modifier-subfamily-v-member-2-kcnv2-associated-retinopathy
#4
JOURNAL ARTICLE
Tomoko Sato, Kazuki Kuniyoshi, Takaaki Hayashi, Hirokazu Nishiwaki, Kei Mizobuchi, Shunji Kusaka
BACKGROUND: KCNV2-associated retinopathy causes a phenotype reported as "cone dystrophy with nyctalopia and supernormal rod responses (CDSRR; OMIM# 610356)," featuring pathognomonic findings on electroretinography (ERG). Here, we report the clinical courses of two siblings with CDSRR. CASE REPORTS: Patient 1: A 3-year-old boy with intermittent exophoria was referred to our hospital. The patient's decimal best-corrected visual acuity (BCVA) at age 6 was 0.7 and 0...
April 17, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38622306/optic-nerve-involvement-in-patients-with-lyme-neuroborreliosis-an-electrophysiological-study
#5
JOURNAL ARTICLE
Jana Szanyi, Jan Kremlacek, Zuzana Kubova, Miroslav Kuba, Frantisek Vit, Jana Langrova, Pavel Gebousky, Juraj Szanyi
PURPOSE: The aim of this neurophysiological study was to retrospectively analyze visual evoked potentials (VEPs) acquired during an examination for diagnosing optic nerve involvement in patients with Lyme neuroborreliosis (LNB). Attention was focused on LNB patients with peripheral facial palsy (PFP) and optic nerve involvement. METHODS: A total of 241 Czech patients were classified as having probable/definite LNB (193/48); of these, 57 were younger than 40 years, with a median age of 26...
April 15, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38613609/questioning-accelerated-hydroxychloroquine-retinopathy
#6
LETTER
Michael F Marmor
No abstract text is available yet for this article.
April 13, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38605262/slope-between-positive-and-negative-erg-components-in-patients-with-open-angle-glaucoma
#7
JOURNAL ARTICLE
Maja Sustar Habjan, Barbara Cvenkel
PURPOSE: To evaluate ERG morphology, in particular the slope between P50 and N95 components of the PERG, as well as between the b-wave and the photopic negative response (PhNR) of the light-adapted (LA) ERG in patients with retinal ganglion cell (RGC) dysfunction due to open-angle glaucoma. METHODS: The PERG and LA-ERG traces of 16 glaucoma patients and 21 age-similar controls were retrospectively analysed. The ERG signal between the peak of the positive component (P50 and b-wave) towards the negative component (N95 and PhNR) was described by a linear regression y = a + bx, where the parameter b indicated the steepness of the P50-N95 and b-PhNR slope...
April 12, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38575772/accelerated-hydroxychloroquine-toxic-retinopathy-response-to-letter
#8
LETTER
Ayushi Mohapatra, Prasad Gupta, Dhanashree Ratra
No abstract text is available yet for this article.
April 5, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38498077/morphological-and-functional-correlations-in-acute-central-serous-chorioretinopathy
#9
JOURNAL ARTICLE
Peter Kiraly, Maja Šuštar Habjan, Jaka Smrekar, Polona Jaki Mekjavić
PURPOSE: We evaluate morphological and functional correlations in patients with acute central serous chorioretinopathy (CSC). METHODS: A prospective study was conducted on 50 patients with an acute CSC episode lasting less than 3 months. At baseline, assessments included optical coherence tomography (OCT), best-corrected visual acuity (BCVA), contrast sensitivity (CS), microperimetry (MP), and multifocal electroretinography (mfERG). A correlation analysis between OCT morphological parameters (maximal subretinal fluid height (SRF), central retinal thickness (CRT), and macular volume (MV)) and functional parameters was conducted on the affected eye for each patient...
March 18, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38488946/iscev-standard-for-clinical-pattern-electroretinography-2024-update
#10
JOURNAL ARTICLE
D A Thompson, M Bach, J J McAnany, M Šuštar Habjan, S Viswanathan, A G Robson
The pattern electroretinogram (PERG) is a localized retinal response evoked by a contrast-reversing pattern, usually a black and white checkerboard, which provides information about macular and retinal ganglion cell function. This document, from the International Society for Clinical Electrophysiology of Vision (ISCEV; www.iscev.org ) presents an updated and revised Standard for clinical PERG testing. This replaces the 2013 and all earlier versions. Minimum protocols for basic PERG stimuli, recording methods and reporting are specified, to promote consistency of methods for diagnosis and monitoring purposes, while responding to evolving clinical practices and technology...
March 15, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38451375/electroretinographic-oscillatory-potentials-in-leber-hereditary-optic-neuropathy
#11
JOURNAL ARTICLE
Mirella T S Barboni, Maja Sustar Habjan, Sanja Petrovic Pajic, Marko Hawlina
PURPOSE: Leber hereditary optic neuropathy (LHON) affects retinal ganglion cells causing severe vision loss. Pattern electroretinogram and photopic negative response (PhNR) of the light-adapted (LA) full-field electroretinogram (ERG) are typically affected in LHON. In the present study, we evaluated dark-adapted (DA) and LA oscillatory potentials (OPs) of the flash ERG in genetically characterized LHON patients to dissociate slow from fast components of the response. METHODS: Seven adult patients (mean age = 28...
March 7, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38416305/effect-of-eccentric-fixation-on-the-steady-state-pattern-electroretinogram
#12
JOURNAL ARTICLE
Evelyn B N Friedel, Julia Haldina, Kathrin Nickel, Michael Bach, Ludger Tebartz van Elst, Sven P Heinrich
PURPOSE: The steady-state pattern electroretinogram (ssPERG) is used to assess retinal ganglion cell function in a variety of research contexts and diagnostic applications. In certain groups of patients or study participants, stable central fixation of the stimulus is not guaranteed. The present study aimed at assessing the effects of misfixation on the ssPERG response to checkerboard reversal stimuli. METHODS: Using two check sizes (0.8° and 15°), we compared ssPERG responses for several amounts of fixation deviation, ranging from 0° to 19° horizontally and from 0° to 14° diagonally...
February 28, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38363513/autoimmune-retinopathy-in-a-patient-with-smoldering-multiple-myeloma-a-case-report
#13
JOURNAL ARTICLE
Zachary Bergman, Taariq Mohammed, Lisa Schocket, Rachid Aouchiche, Mary A Johnson
PURPOSE: Multiple myeloma (MM) is a plasma cell dyscrasia leading to proliferation of monoclonal plasma cells. Ocular involvement in multiple myeloma is uncommon but can occur. The ocular manifestations of MM may include the cornea, uvea, and retinal vasculature. We present a rare case of autoimmune retinopathy associated with smoldering MM. CASE: A 76-year-old female with no significant past medical or ocular history presented with four months of worsening vision, difficulty with night driving, and loss of peripheral vision...
February 16, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38353842/the-ips-and-iscev-joint-guidelines-for-full-field-stimulus-testing
#14
EDITORIAL
J K Jolly, C Matsumoto, R Hamilton
No abstract text is available yet for this article.
February 14, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38351363/videoocular-assessment-of-eye-movement-activity-in-an-ataxia-telangiectasia-a-case-study
#15
JOURNAL ARTICLE
Sofia A Mironets, Marina A Shurupova, Alexander F Karelin
PURPOSE: Ataxia-telangiectasia (A-T) is an autosomal recessive disorder characterized by progressive neurological deficits, including prominent oculomotor dysfunction. We report 5 cases of eye movement assessment in children 9-15 years old with A-T. METHODS: Three different oculomotor tasks (gaze holding, visually guided saccades and visual search) were used, and video-oculography was performed. Additionally, the scale for the assessment and rating of ataxia (SARA) score was used to assess severity of the cerebellar ataxia...
February 14, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38265517/case-of-persistent-corneal-epithelial-damage-after-cataract-surgery-leading-to-diagnosis-of-vitamin-a-deficiency
#16
JOURNAL ARTICLE
Fuyuki Yamada, Kumiko Kato, Ryunosuke Nagashima, Yuka Yonekawa, Yuzen Kashima, Mineo Kondo
PURPOSE: To report our findings of reduced full-field electroretinograms (ff-ERGs) and abnormal optical coherence tomographic (OCT) images in a patient with poor visual acuity after cataract surgery who was eventually diagnosed with vitamin A deficiency (VAD). METHODS: This was a clinical study of a patient who complained of blurred vision after cataract surgery. To determine the cause of the reduced vision, we recorded full-field electroretinograms (ff-ERGs) to determine the scotopic and photopic status of the retina...
January 24, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38243039/sensitivity-and-specificity-of-the-uniform-field-electroretinogram-in-glaucoma-detection-in-comparison-to-the-pattern-electroretinogram
#17
JOURNAL ARTICLE
Asma Hermas, Catherine Tsilfidis, Rustum Karanjia, Garfield Miller, Ange-Lynca Kantungane, Amanda El-Salibi, Irfan N Kherani, Shveta Bali, Stuart Coupland
PURPOSE: To determine the ability of the photopic negative response (PhNR) of the uniform field electroretinogram (UF-ERG) to identify early glaucomatous changes in comparison to the checkerboard and bar stimuli of the pattern electroretinogram (PERG). METHODS: Forty-nine glaucoma patients were classified into two groups: glaucoma-suspect (23 eyes) and early to moderate glaucoma (30 eyes), based on their clinical examination and the results of standard automated perimetry...
January 20, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38238632/iscev-and-ips-guideline-for-the-full-field-stimulus-test-fst
#18
JOURNAL ARTICLE
J K Jolly, J R Grigg, A M McKendrick, K Fujinami, A V Cideciyan, D A Thompson, C Matsumoto, R Asaoka, C Johnson, M W Dul, P H Artes, A G Robson
The full-field stimulus test (FST) is a psychophysical technique designed for the measurement of visual function in low vision. The method involves the use of a ganzfeld stimulator, as used in routine full-field electroretinography, to deliver full-field flashes of light. This guideline was developed jointly by the International Society for Clinical Electrophysiology of Vision (ISCEV) and Imaging and Perimetry Society (IPS) in order to provide technical information, promote consistency of testing and reporting, and encourage convergence of methods for FST...
January 18, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38206458/unusual-oct-findings-in-a-patient-with-cabp4-associated-cone-rod-synaptic-disorder
#19
JOURNAL ARTICLE
Jit Kai Tan, Gavin Arno, Dragana Josifova, Moin D Mohamed, Omar A Mahroo
PURPOSE: Bi-allelic variants in CABP4 are associated with congenital cone-rod synaptic disorder, which has also been classified, electrophysiologically, as incomplete congenital stationary night blindness (iCSNB). We describe clinical findings in a patient who demonstrated an unusual macular optical coherence tomography (OCT) phenotype, not previously reported in this condition. METHODS: Our patient underwent multimodal retinal imaging, international standard full-field ERG testing and whole genome sequencing...
January 11, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
https://read.qxmd.com/read/38172268/genetic-morphological-and-electrophysiological-findings-in-a-patient-with-a-rare-pathogenic-variant-in-the-rs1-gene
#20
JOURNAL ARTICLE
Lorrana Souza Azevedo, Márcio Augusto Moraes Alvarez, Gabriel Izan Santos Botelho, Alexandre Antônio Marques Rosa, Givago Silva Souza
PURPOSE: In this study, we report a case of a young adult with X-linked juvenile retinoschisis (XLRS) with a rare pathogenic variant in the RS1 gene (c.522 + 2 T > A). METHODS: Ophthalmological evaluation, optical coherence tomography, full-field and multifocal electroretinograms and extensive genetic screening of genes related to visual loss were carried out in the participant. RESULTS: Clinical ophthalmological exams revealed a mild to moderate impairment of visual acuity...
January 3, 2024: Documenta Ophthalmologica. Advances in Ophthalmology
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