journal
https://read.qxmd.com/read/38072917/clinical-and-sociodemographic-features-in-offspring-aged-0-3%C3%A2-years-of-mothers-with-schizophrenia-spectrum-disorders-a-descriptive-cross-sectional-study
#41
JOURNAL ARTICLE
Emilie Edvardsen, Mala Moszkowicz, Anne Lise Olsen, Michella Heinrichsen, Anne Katrine Pagsberg
OBJECTIVE: Offspring of parents with schizophrenia spectrum disorders (SSD) have an increased risk of neurodevelopmental disturbances. However, the ability to provide very early interventions to support these children and their families requires profound knowledge regarding characteristic features of both the parents and their offspring. Information on this subject is currently sparse. The aim of the present study is to investigate clinical and sociodemographic variables in offspring in the age range of 0-3 years of mothers diagnosed with SSD...
December 10, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/38072006/borderline-personality-disorder-and-the-diagnostic-co-occurrence-of-mental-health-disorders-and-somatic-diseases-a-controlled-prospective-national-register-based-study
#42
JOURNAL ARTICLE
L H Hastrup, P Jennum, R Ibsen, J Kjellberg, E Simonsen
OBJECTIVE: Information on borderline personality disorder (BPD) and its comorbidities is often limited to concentrate on a few diagnoses. The aim of the study was to use national register data to investigate all diagnostic co-occurring mental health disorders and somatic diseases 3 years before and after initial BPD diagnosis compared with a matched control group. METHOD: The study was a register-based cohort of 2756 patients with incident BPD (ICD F60.3) and 11,024 matched controls, during 2002-2016...
December 10, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/38072004/a-naturalistic-effectiveness-study-of-maintenance-therapies-for-the-bipolar-disorders
#43
JOURNAL ARTICLE
Michael J Spoelma, Joanne Leidreiter, Adam Bayes, Artin Jebejian, Gordon Parker
BACKGROUND: Treatment decision-making for individuals with bipolar disorder can be difficult. Recommendations from clinical practice guidelines can be affected by multiple methodological limitations, while pharmaco-epidemiological data suggest great variety in prescription practices across regions. Given these inconsistencies, this study aimed to provide an alternative perspective on the effectiveness of common bipolar disorder maintenance treatments through considering naturalistic data...
December 10, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/38057974/disease-trajectory-of-high-neuroticism-and-the-relevance-to-psychiatric-disorders-a-retro-prospective-cohort-study
#44
JOURNAL ARTICLE
Ding Xia, Xin Han, Yu Zeng, Jingru Wang, Kelin Xu, Tiejun Zhang, Yanfeng Jiang, Xingdong Chen, Huan Song, Chen Suo
BACKGROUND: Neuroticism is a psychological personality trait that has a significant impact on public health and is also a potential predisposing factor for adverse disease outcomes; however, comprehensive studies of the subsequently developed conditions are lacking. The starting point of disease trajectory in terms of genetic variation remains unclear. METHOD: Our study included 344,609 adult participants from the UK Biobank cohort who were virtually followed up from January 1, 1997...
December 6, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/38056448/trends-in-psychotherapy-utilization-for-perinatal-mental-health-2008-2020
#45
JOURNAL ARTICLE
Karen M Tabb, Dana C Beck, Xiaosong Zhang, Stephanie Hall, Anca Tilea, Gloria Sugg, Amy Schroeder, Vanessa K Dalton, Kara Zivin
No abstract text is available yet for this article.
December 6, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37985005/adaptive-and-maladaptive-emotion-regulation-in-bipolar-disorder
#46
EDITORIAL
Thomas Frodl
No abstract text is available yet for this article.
December 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37904016/meta-analysis-of-clinical-risk-factors-for-suicide-among-people-presenting-to-emergency-departments-and-general-hospitals-with-suicidal-thoughts-and-behaviours
#47
REVIEW
Cameron Grover, Jacqueline Huber, Matthew Brewer, Ashna Basu, Matthew Large
BACKGROUND: Suicidal thoughts and behaviours (STB) are a common reason for presentation to emergency departments and general hospitals. A meta-analysis of the strength of clinical risk factors for subsequent suicide might aid understanding of suicidal behaviour and help suicide prevention. METHODS: We conducted a meta-analysis of cohort and controlled studies on clinical risk factors and later suicide among people presenting to emergency departments and general hospitals with STB...
December 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37899506/clozapine-augmentation-with-long-acting-antipsychotic-injections-a-case-series-and-systematic-review
#48
JOURNAL ARTICLE
Ebenezer Oloyede, Aikaterini Dima, David Taylor, Henry Cheung, Olubanke Dzahini, Sukhi Shergill, Eromona Whiskey
BACKGROUND: Up to 30% of patients with a diagnosis of treatment-resistant psychosis remain symptomatic despite an optimal trial with the gold standard treatment, clozapine. Emerging evidence suggests the clinical utility of long-acting injections (LAI) in such clinical scenarios. In this study, we aimed to describe clozapine augmentation with LAIs in an inner London hospital and explore the literature on the clinical effectiveness of this treatment modality. METHODS: Patients prescribed clozapine, who were commenced on a LAI between 2007 and 2023 by the United Kingdom's largest mental health trust, were identified from electronic patient records...
December 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37740499/correlation-between-emotion-dysregulation-and-mood-symptoms-of-bipolar-disorder-a-systematic-review-and-meta-analysis
#49
REVIEW
Vincenzo Oliva, Michele De Prisco, Giovanna Fico, Chiara Possidente, Lydia Fortea, Laura Montejo, Gerard Anmella, Diego Hidalgo-Mazzei, Iria Grande, Andrea Murru, Michele Fornaro, Andrea de Bartolomeis, Alyson Dodd, Giuseppe Fanelli, Chiara Fabbri, Alessandro Serretti, Eduard Vieta, Joaquim Radua
BACKGROUND: Emotion dysregulation (ED) is a transdiagnostic construct characterized by difficulties regulating intense emotions. People with bipolar disorder (BD) are more likely to show ED and use maladaptive emotion regulation strategies than adaptive ones. However, little is known about whether ED in BD is a trait or it is rather an epiphenomenon of mood symptoms. METHODS: We conducted a systematic review and meta-analysis of the evidence across major literature databases reporting correlations between measures of emotion regulation (overall ED and different emotion regulation strategies) and measures of depressive and (hypo)manic symptoms in BD from inception until April 12th, 2022...
December 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/38030136/reduced-mitochondrial-respiratory-capacity-in-patients-with-acute-episodes-of-bipolar-disorder-could-bipolar-disorder-be-a-state-dependent-mitochondrial-disease
#50
JOURNAL ARTICLE
Anna Giménez-Palomo, Mariona Guitart-Mampel, Ana Meseguer, Roger Borràs, Francesc Josep García-García, Esther Tobías, Laura Valls, Xavier Alsina-Restoy, Gemma Roqué, Ester Sánchez, Josep Roca, Gerard Anmella, Marc Valentí, Lorenzo Bracco, Helena Andreu, Sergi Salmerón, Lluc Colomer, Joaquim Radua, Norma Verdolini, Michael Berk, Eduard Vieta, Glòria Garrabou, Isabella Pacchiarotti
BACKGROUND: Bipolar disorder (BD) is a chronic and recurrent disease characterized by acute mood episodes and periods of euthymia. The available literature postulates that a biphasic dysregulation of mitochondrial bioenergetics might underpin the neurobiology of BD. However, most studies focused on inter-subject differences rather than intra-subject variations between different mood states. To test this hypothesis, in this preliminary proof-of-concept study, we measured in vivo mitochondrial respiration in patients with BD during a mood episode and investigated differences compared to healthy controls (HC) and to the same patients upon clinical remission...
November 29, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37990478/prenatal-antidepressant-exposure-and-the-risk-of-decreased-gestational-age-and-lower-birthweight-a-polygenic-score-approach-to-investigate-confounding-by-indication
#51
JOURNAL ARTICLE
Anna-Sophie Rommel, Birgitte Dige Semark, Xiaoqin Liu, Kathrine Bang Madsen, Esben Agerbo, Trine Munk-Olsen, Liselotte Vogdrup Petersen, Veerle Bergink
INTRODUCTION: Prenatal antidepressant exposure has been associated with lower gestational age and birthweight. Yet, unmeasured residual confounding may inflate this association. We explored if maternal genetic liability for major depression explains part of the association of antidepressant use in pregnancy with lower gestational age and birthweight. MATERIAL AND METHODS: We employed the maternal polygenic score (PGS) for major depression as a measure of genetic liability...
November 21, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37990476/prescription-patterns-in-unipolar-depression-a-nationwide-danish-register-based-study-of-113-175-individuals-followed-for-10%C3%A2-years
#52
JOURNAL ARTICLE
Anders Jorgensen, Emma Neble Larsen, Mathilde Marie Brünnich Sloth, Lars Vedel Kessing, Merete Osler
BACKGROUND: Evidence-based use of antidepressant medications is of major clinical importance. We aimed to uncover precription patterns in a large cohort of patients with unipolar depression. MATERIAL AND METHODS: Using Danish nationwide registers, we identified individuals with a first-time hospital diagnosis of unipolar depression between January 1st, 2001, and December 31st, 2016. Redemeed prescriptions of antidepressants from five years before to five years after diagnosis were retreived...
November 21, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37986171/electroconvulsive-therapy-related-anxiety-in-patients-with-depression-the-influence-of-cognitive-coping-styles
#53
JOURNAL ARTICLE
Chelsea Verledens, Jasmien Obbels, Liese Van den Eynde, Eva Pilato, Shauni Verspecht, Kaat Hebbrecht, Emma De Schuyteneer, Kristof Vansteelandt, Pascal Sienaert
INTRODUCTION: Electroconvulsive therapy (ECT) related anxiety (ERA) is a common phenomenon with high individual variability. The way patients cognitively cope with the prospects of receiving ECT could be a mechanism explaining individual differences in ERA. Cognitive coping like monitoring (information seeking, paying attention to consequences) and blunting (seeking distraction and reassurance) has been linked to anxiety in various medical settings, with monitoring leading to more and blunting to less anxiety...
November 20, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37985246/effect-of-severity-of-depression-on-augmentation-of-antidepressant-medication-in-young-adults-with-depression
#54
JOURNAL ARTICLE
Pasi Lampela, Antti Tanskanen, Markku Lähteenvuo, Jari Tiihonen, Heidi Taipale
BACKGROUND: Antipsychotics (AP) have been used to augment antidepressant (AD) medication in treatment-resistant depression. In this study we examined factors (including severity of depression and initial antidepressant) affecting AP augmentation, as well as which APs were initiated as augmentation in young adults. METHODS: Data were extracted from Finnish nationwide registers. Of persons aged 18-29 years diagnosed with a depression during 2004-2017 we focused on incident AD users (who initiated AD 6 months before and after the diagnosis) whose severity level of depression was recorded (N = 21,966)...
November 20, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37974390/brain-derived-neurotrophic-factor-levels-in-perinatal-depression-a-systematic-review-and-meta-analysis
#55
REVIEW
Kyana Jafarabady, Arman Shafiee, Razman Arabzadeh Bahri, Shahryar Rajai Firouzabadi, Ida Mohammadi, Mohammad Javad Amini
BACKGROUND: This systematic review and meta-analysis aim to synthesize the available evidence and determine the overall brain-derived neurotrophic factor (BDNF) levels in individuals diagnosed with perinatal depression (PND). METHODS: We performed a thorough search of electronic databases, including PubMed, Embase, PsycINFO, and Web of Science, from their start until April 30, 2023. Our search strategy involved using specific keywords and medical subject headings (MeSH) terms related to BDNF, perinatal, post-partum, and antepartum depression...
November 16, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37961014/prediction-models-of-suicide-and-non-fatal-suicide-attempt-after-discharge-from-a-psychiatric-inpatient-stay-a-machine-learning-approach-on-nationwide-danish-registers
#56
JOURNAL ARTICLE
Sara Dorthea Nielsen, Rune H B Christensen, Trine Madsen, Karen-Inge Karstoft, Line Clemmensen, Michael E Benros
INTRODUCTION: To develop machine learning models capable of predicting suicide and non-fatal suicide attempt as separate outcomes in the first 30 days after discharge from a psychiatric inpatient stay. METHODS: Prospective cohort study using nationwide Danish registry data. We included individuals who were 18 years or older, and all discharges from psychiatric hospitalizations in Denmark from 1995 to 2018. We trained predictive models using 10-fold cross validation on 80% of the data and did testing on the remaining 20%...
November 14, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37950362/cognitive-deficits-among-people-with-schizophrenia-and-prediabetes-or-diabetes
#57
JOURNAL ARTICLE
Alexander Panickacheril John, Thynn Mya, Darren Haywood
INTRODUCTION: Both type 2 diabetes mellitus (T2DM) and schizophrenia are known to be associated with cognitive deficits. The impact of the comorbidities of T2DM or prediabetes (PD) on cognition among people with schizophrenia has been poorly researched. We evaluated the cognitive functioning of patients with schizophrenia and PD or T2DM and compared them to patients with schizophrenia with normal blood sugar. METHODS: We retrospectively collated data on cognition, fasting blood glucose (FBG), lipids and other selected demographic and clinical variables of 171 patients with schizophrenia and 16 patients with schizoaffective disorder who were admitted to an inpatient rehabilitation facility in Western Australia from 2011 to 2018...
November 10, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37933529/pregnancy-intention-in-relation-to-maternal-and-neonatal-outcomes-in-women-with-versus-without-psychiatric-diagnoses
#58
JOURNAL ARTICLE
Noralie N Schonewille, Nini H Jonkman, Anne A M W van Kempen, Maria G van Pampus, Odile A van den Heuvel, Birit F P Broekman
BACKGROUND: Studies have identified adverse maternal and neonatal outcomes for women with psychiatric disorders. Additionally, psychiatric disorders may pose an increased risk for unintended pregnancies (UPs) which in turn may also impact negatively on outcomes. The present study aims to compare the incidence of UPs in women with versus without current/past psychiatric diagnoses and investigates whether psychiatric history modifies the relation between delivery outcomes in women with and without UPs...
November 7, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37933520/smoking-and-severe-mental-illness-drawing-inference-on-the-directionality-of-the-association-requires-careful-consideration-of-the-temporality-of-the-data
#59
LETTER
Marie Krab Lund, Mikkel Højlund, Lars Christian Lund
No abstract text is available yet for this article.
November 7, 2023: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/37931907/women-with-depression-in-pregnancy-or-a-history-of-depression-have-decreased-quality-of-mentalization-in-the-speech-to-their-infants
#60
JOURNAL ARTICLE
Lavinia Rebecchini, Rebecca H Bind, Beatrice Allegri, Arianna Zamparelli, Alessandra Biaggi, Katie Hazelgrove, Sarah Osborne, Susan Conroy, Susan Pawlby, Vaheshta Sethna, Carmine M Pariante
BACKGROUND: Our study aims to understand whether depression, either in pregnancy or lifetime, affects cognitive biases (comprising the attentional focus and affective state) and mentalizing features (ability to understand children's internal mental states, thereby detecting and comprehending their behavior and intention), in maternal speech during mother-infant interaction in the first postnatal year. METHODS: We recruited 115 pregnant women (44 healthy, 46 with major depressive disorder [MDD] in pregnancy, and 25 with a history of MDD but healthy pregnancy) at 25 weeks' gestation...
November 6, 2023: Acta Psychiatrica Scandinavica
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