Sofia Waissbluth, Agustín D Martínez, Cindel Figueroa-Cares, Helmuth A Sánchez, Juan C Maass
BACKGROUND: Cisplatin appears to enter the cochlear cells through the organic cation transporter 2 (OCT2). There is recent evidence that multidrug and toxin extrusion protein 1 (MATE1) is involved in cisplatin-induced nephrotoxicity. Its presence and role in the ear are unknown. AIMS/OBJECTIVES: Evaluate the presence and localization of MATE1, and determine the localization of OCT2, in the cochlea. Evaluate cisplatin uptake with regard to MATE1 and OCT2 expression...
March 21, 2023: Acta Oto-laryngologica
Junyi Liang, Wen Xie, Wenjuan Yao, Maoli Duan
BACKGROUND: Numerical simulations can reflect the changes in physiological properties caused by various factors in the cochlea. AIMS/OBJECTIVE: To analyze the influence of lesions of the basilar membrane (BM) on the dynamic response of the middle ear. METHOD: Based on healthy human ear CT scan images, use PATRAN software to build a three-dimensional finite element model of the human ear, then apply NASTRAN software to conduct analysis of solid-fluid coupled frequency response...
March 20, 2023: Acta Oto-laryngologica
Li Wang, Xi Zeng, Kai Li, Yunxin Lu, Dongxiao Nong
BACKGROUND: Laryngeal carcinomas cause vocal cord (VC) mobility problems. Other than evaluation through flexible laryngoscopy, rare reports concerning CT findings for the motion of the VC or arytenoid cartilage (AC) are found. AIMS/OBJECTIVES: To explore a novel evaluation of the mobility of the AC in glottic carcinoma. MATERIAL AND METHODS: In 39 patients with glottic carcinoma grouped upon lesion locations and AC mobilities, laryngeal CT scans were collected during inspiration and phonation...
March 20, 2023: Acta Oto-laryngologica
Ramzi R Maalouf, Morgane Marc, Payal Mukherjee, Vincent Van Rompaey, Michael Eliezer, Charlotte Hautefort, Benjamin Verillaud, Philippe Herman, Romain Kania
BACKGROUND: The surgical treatment of otosclerosis consists of the replacement of the stapes using a piston. AIMS/OBJECTIVES: The objective of this study is to assess the audiometric results and quality of life (QOL) of patients who underwent surgery for otosclerosis by stapedectomy with fascia interposition (STIP) or by stapedotomy using CO2 laser (SLaser) without fascia interposition. MATERIAL AND METHODS: Ninety-one patients operated on for otosclerosis by STIP (40 patients) and by SLaser (51 patients) were included...
March 20, 2023: Acta Oto-laryngologica
(no author information available yet)
No abstract text is available yet for this article.
March 13, 2023: Acta Oto-laryngologica
Zhi-Ting Chen, Yichen Guo, Jing Zhang, Xiaobing Huang, Jianhong Wang
BACKGROUND: There have been few studies to date exploring prognostic outcomes associated with idiopathic sudden sensorineural hearing loss (ISSNHL) in order adults. OBJECTIVE: This investigation was designed to explore the relationship between atherosclerosis-related risk factors and ISSNHL outcomes among older individuals. MATERIAL AND METHODS: In total, 172 older adults diagnosed ISSNHL from 2016 to 2021 were retrospectively evaluated to compare demographic and clinical test results...
March 10, 2023: Acta Oto-laryngologica
Li Jin, Xueying Pan, Tuanfang Yin, Jihao Ren, Wei Liu
BACKGROUND: The surgical outcomes following tympanic membrane (TM) repair are affected by many factors. OBJECTIVES: To evaluate the efficacy of endoscopic porcine small intestine submucosa graft (PSISG) myringoplasty by comparing with endoscopic myringoplasty with temporal fascia (TF) and perichondrium (PC). METHODS: We conducted a retrospective comparative study that a total of 98 patients with TM perforations were included. The patients underwent endoscopic myringoplasty using PSISG, TF or PC as the graft...
March 10, 2023: Acta Oto-laryngologica
Ricardo Bartel, Francesc Cruellas, Miguel Garcia-Wagner, Miriam Hamdan, Gabriel Huguet, Marta Mesalles, Anna Penella
Background: Chronic mucosal otitis media is a very common ear disease for which patients attend otolaryngology clinics. Most of these patients present with actively discharging ears. Aims/Objectives: This study aims to observe the middle ear space pathology and obtain surgical outcomes as a treatment for patients with advanced chronic mucosal otitis media with a transcanal endoscopic ear surgery approach. Materials and methods: A prospective study was designed, and patients suffering from chronic mucosal otitis media in the active suppurative phase with an air-bone gap larger than 20 dB were included...
March 10, 2023: Acta Oto-laryngologica
Kaitlyn A Brooks, Nathaniel S Neptune, Douglas E Mattox
BACKGROUND: In 2022, Mpox (MPX) has become clinically relevant as otolaryngologists are evaluating this exotic disease process due to its many otolaryngologic manifestations. AIMS/OBJECTIVE: To characterize our cohort of otolaryngology-relevant MPX confirmed cases. MATERIALS AND METHODS: A descriptive case series was performed via retrospective review. Adult patients who underwent inpatient or emergency department otolaryngology consultation at an Emory University-affiliated tertiary care level hospital for MPX were included...
March 10, 2023: Acta Oto-laryngologica
Yisi Feng, Zhuohao Li, Wuhui He, Ying Xiong, Yu Si, Zhigang Zhang
BACKGROUND: Acquired cholesteatoma is characterized by hyper-keratinized squamous epithelium and bone destruction. However, direct evidence for hyper-keratinized epidermis promoting bone destruction is lacking. AIMS/OBJECTIVES: To determine whether higher degree of keratinization correlated with severe bone destruction and further offer direct evidence for keratinocyte-inducing osteoclastogenesis. MATERIALS AND METHODS: Histological changes and clinical relevance were analyzed in human-acquired cholesteatoma...
March 8, 2023: Acta Oto-laryngologica
Elisabetta Zanoletti, Gino Marioni, Piero Nicolai, Antonio Mazzoni
BACKGROUND: Lateral skull base is a complex area between the brain and the neck that is characterized by a large anatomic variability in narrow spaces and wide heterogeneity of tissues. The complexity of the anatomy makes it more difficult to accurately identify tumor spread and surgical planning is here particularly demanding. AIMS: Oncological skull base surgery is conceived for malignant lesions originating in, secondarily infiltrating, or in close proximity to the lateral skull base...
March 8, 2023: Acta Oto-laryngologica
José Lucas Barbosa da Silva, Lucas Kanieski Anzolin, Samuel Pissinati Nicacio, Richard L Doty, Fábio de Rezende Pinna, Richard Louis Voegels, Marco Aurélio Fornazieri
BACKGROUND: Previous studies demonstrated the difficulty of patients with Head and Neck Cancer (HNC) in sensing food taste, a function in which olfaction has a significant role. However, neither study employed psychophysical tests or control groups to establish the veracity of such complaints. AIMS/OBJECTIVES: In this study, we quantitatively tested the olfactory function of HNC individuals and compared their function to that of healthy controls. METHODS: Thirty-one HNC naïve treatment patients and thirty-one controls, matched for sex, age, schooling, and smoking, were tested with the University of Pennsylvania Smell Identification Test (UPSIT)...
March 1, 2023: Acta Oto-laryngologica
Mi Rye Bae, Kyung-Do Han, Sang-Hyun Park, Yoo-Sam Chung
BACKGROUND: Adenotonsillectomy is the most commonly performed surgery in children. AIMS: To evaluate the effects of pediatric adenotonsillectomy on health care utilization. METHODS: From 2006 to 2017, age/sex-matched adenotonsillectomy participants ( n  = 243.396) and controls ( n  = 730.188) were selected (62% of male and 38% of female. 47% age≦ 6, 16% 7-9years, 8% 10-12years, 29% 13-18years). The changes in outpatient visits, hospitalization days, and drug prescriptions due to a URI, asthma, and rhinitis before and after the surgery date (from 13 months to 1 month) were compared...
March 1, 2023: Acta Oto-laryngologica
Francesco Bussu, Luca Tagliaferri, Claudia Crescio, Davide Rizzo, Roberto Gallus, Claudio Parrilla, Bruno Fionda, Valentina Lancellotta, Gian Carlo Mattiucci, Jacopo Galli
BACKGROUND: Nasal vestibule squamous cell carcinoma (NVSCC) is an ill-defined underestimated condition. Aim/objective: To define the current standard of care. MATERIAL AND METHODS: We review recent acquisitions concerning clinical features and therapeutic approaches. RESULTS: The current AJCC staging system, which attributes to nasal vestibule the same topographic code as nasal cavity proper and the same T-classification criteria as ethmoid, appears inadequate...
February 28, 2023: Acta Oto-laryngologica
Tadao Yoshida, Masumi Kobayashi, Satofumi Sugimoto, Yukari Fukunaga, Daisuke Hara, Shinji Naganawa, Michihiko Sone
BACKGROUND: Listening difficulties (LiD) present difficulties in listening and paying attention to spoken information despite normal pure tone audiometry. Endolymphatic hydrops (EH) is a common inner ear condition associated with Ménière's disease but may also be present in the asymptomatic ear. OBJECTIVES: Using magnetic resonance imaging, we investigated EH in patients with LiD and assessed whether the severity of EH was related to the results of auditory processing tests (APTs)...
February 28, 2023: Acta Oto-laryngologica
Qin Wang, Panpan Bian, Shengjin Bai, Chi Chen, Yanli Wang, Yufen Guo, Baicheng Xu
BACKGROUND: Central lucency of the bony island of the lateral semicircular canal (LSCC) is commonly found in patients with congenital severe-to-profound sensorineural hearing loss (SNHL). OBJECTIVE: Exploring the significance of bony island lucency of LSCC in congenital severe-to-profound SNHL patients. MATERIAL AND METHODS: Retrospective measurements of the inner ear structures were made on axial temporal bone CT scans from 182 (364 ears) congenital severe-to-profound SNHL patients and 50 (100 ears) tympanic membrane perforation (TMP) patients...
February 25, 2023: Acta Oto-laryngologica
Lianrong Guo, Yongjin Su, Zhi Cai, Yuanyuan Yang
BACKGROUND: Transcanal endoscopic surgery offers advantages for congenital cholesteatoma (CC) which is expanding cystic mass located on an intact tympanic membrane. OBJECTIVES: To determine the efficacy of transcanal endoscopic ear surgery for the treatment of CC. MATERIAL AND METHODS: Eleven patients with CC confined to the middle ear underwent transcanal endoscopic ear surgery by surgeons who were skilled in otoscopic surgery. According to the Potsic classification, four, three, and four patients had lesions in stages 1, 2, and 3, respectively...
February 24, 2023: Acta Oto-laryngologica
Jiaying Huang, Yongtian Xu, Ling Li, Wei Ai
BACKGROUND: Hyperlipidemia may be part of the important mechanisms for the development of idiopathic sudden sensorineural hearing loss (ISSNHL). AIMS: So the purpose of this study was to evaluate the relationship between changes in blood lipid levels and ISSNHL. MATERIALS AND METHODS: We enrolled 90 ISSNHL patients in our hospital using a retrospective study design from 2019.1 to 2021.12. Blood levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein (LDL-C)...
February 22, 2023: Acta Oto-laryngologica
Shuyue Wang, Haiyao Zheng, Tao Liao
BACKGROUND: A painless and effective treatment of childhood epistaxis is needed. OBJECTIVE: To observe the effectiveness of low-intensity diode (Lid) laser in treating epistaxis complicated with allergic rhinitis in children. METHODS: Our study is a prospective, randomized, controlled, registry trial (NO. 202001201) involving 44 recurrent epistaxis children (<14 years old) with or without Allergic Rhinitis (AR) in our hospital. They were divided randomly into the Laser and Control groups...
February 20, 2023: Acta Oto-laryngologica
Rasheed Omobolaji Alabi, Mohammed Elmusrati, Ilmo Leivo, Alhadi Almangush, Antti A Mäkitie
BACKGROUND: A significant number of tongue squamous cell carcinoma (TSCC) patients are diagnosed at late stage. OBJECTIVES: We primarily aimed to develop a machine learning (ML) model based on ensemble ML paradigm to stratify advanced-stage TSCC patients into the likelihood of overall survival (OS) for evidence-based treatment. We compared the survival outcome of patients who received either surgical treatment only (Sx) or surgery combined with postoperative radiotherapy (Sx + RT) or postoperative chemoradiotherapy (Sx + CRT)...
February 15, 2023: Acta Oto-laryngologica
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.