Kazunori Matsuda, Junya Fukuda, Go Sato, Momoyo Matsuoka, Takefumi Kamakura, Atsuhiko Uno, Eiji Kondo, Takahiro Azuma, Yoshiaki Kitamura, Koichi Tomita, Tadashi Kitahara, Noriaki Takeda
BACKGROUND: Diazepam, a gamma-aminobutyric acid type A receptor agonist, is classified as a vestibular suppressant and is effective in treating acute vertigo. However, its effects on vestibular compensation (VC) remain unclear. OBJECTIVES: We examined the effects of continuous administration of diazepam on the frequency of spontaneous nystagmus (SN) after unilateral labyrinthectomy (UL) as an index of the initial process of VC in rats. MATERIALS AND METHODS: Diazepam was continuously administered at doses of 3...
August 22, 2023: Acta Oto-laryngologica