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Acta Obstetricia et Gynecologica Scandinavica

Michaela Granfors, Olof Stephansson, Margit Endler, Maria Jonsson, Anna Sandström, Anna-Karin Wikström
INTRODUCTION: The impact of placenta previa on pregnancy, delivery and infant outcomes has been extensively studied. Less is however known about the possible association of placental location other than previa with pregnancy outcomes. The aim of this study was to investigate if placental location other than previa is associated with adverse pregnancy, delivery and infant outcomes. MATERIAL AND METHODS: This is a population-based cohort study, with data from the regional population-based Stockholm-Gotland Obstetric Cohort, Sweden, from 2008 to 2014...
February 15, 2019: Acta Obstetricia et Gynecologica Scandinavica
Iqbal Al-Zirqi, Anne Kjersti Daltveit, Siri Vangen
INTRODUCTION: Complete uterine rupture, a rare peripartum complication, is often associated with a catastrophic outcome for both mother and child. However, few studies have investigated large data sets to evaluate maternal outcomes after complete ruptures, particularly in unscarred uteri. This paucity of studies is partly due to the rarity of both the event and the serious outcomes, such as peripartum hysterectomy and maternal death. The incidence of uterine rupture is expected to increase, due to increasing cesarean section rates worldwide...
February 14, 2019: Acta Obstetricia et Gynecologica Scandinavica
Priya Bhide, Jyotsna Pundir, Roy Homburg, Ganesh Acharya
INTRODUCTION: Certain medical disorders as well as their management may affect gonadal function. Recent advances in the management these conditions accompanied by the availability and success of methods of fertility preservation has highlighted the need for assessment of ovarian reserve in childhood and adolescence. Serum anti-Mullerian hormone (AMH) and antral follicle count are well established markers of ovarian reserve and serum inhibin has also been used. However, literature on reference ranges for ovarian reserve markers in this age group is relatively scarce...
February 13, 2019: Acta Obstetricia et Gynecologica Scandinavica
Stine Gry Kristensen, Susanne Elisabeth Pors, Liv la Cour Poulsen, Signe Taasti Andersen, Yu Wakimoto, Claus Yding Andersen
INTRODUCTION: Young women with a cancer diagnosis often have very little time to decide whether or not to commence on fertility preserving strategies before initiating potentially sterilizing cancer treatment. Minimizing the interval from opting for fertility preservation to completion of the procedure will reduce the potential risk of delaying cancer treatment. In the current study, we have evaluated the period of time from referral to ovarian tissue cryopreservation (OTC) to actual freezing of the tissue in a cohort of Danish women...
February 13, 2019: Acta Obstetricia et Gynecologica Scandinavica
Alessandra Alteri, Valerio Pisaturo, Daniela Nogueira, Arianna D'Angelo
The aim of this review is to provide current knowledge on fertility preservation for nonmedical reasons in women willing to postpone childbearing. The topic is highly debatable starting from the disagreement about its terminology, the number of eggs necessary to predict chances of success, and the safety and socio/ethical point of view. Cost analysis and discrepancies among countries recommendations and regulations are described to confirm the controversies and unsolved issues around this very interesting topic...
February 13, 2019: Acta Obstetricia et Gynecologica Scandinavica
Enrico Ferrazzi, Christoph Lees, Ganesh Acharya
The ductus venosus plays a critical role in circulatory adaptation to hypoxia in fetal growth restriction, but the mechanisms still remain controversial. Increased shunting of blood through the ductus venosus under hypoxic conditions has been shown in animal and human studies. The hemodynamic laws governing the accelerated flow in this vessel suggest that any dilatation at its isthmus, which increases the blood flow shunting to the heart, is associated with a low, absent or reversed a-wave, and a high pulsatility index...
February 11, 2019: Acta Obstetricia et Gynecologica Scandinavica
Emelie Wolgast, Lotta Lindh-Åstrand, Caroline Lilliecreutz
INTRODUCTION: Medication use for different kinds of symptoms and diseases during pregnancy is common. When counseling the pregnant woman, an understanding of her perceptions concerning the use of medication as well as possible associated anxiety and obstacles is important in order to ensure high adherence to the treatment regimen. MATERIAL AND METHODS: A questionnaire was developed regarding the use of medication, perceptions on use of medication, as well as perceptions about pregnancy outcomes in association with medication use during pregnancy...
February 10, 2019: Acta Obstetricia et Gynecologica Scandinavica
Benedetta Iussig, Roberta Maggiulli, Gemma Fabozzi, Sara Bertelle, Alberto Vaiarelli, Danilo Cimadomo, Filippo Maria Ubaldi, Laura Rienzi
The term "cryopreservation" refers to the process of cooling cells and tissues and storing them at subzero temperatures in order to stop all biologic activity and preserve their viability and physiologic competences for future use. Cooling to subzero temperatures is not a physiological condition for human cells; this is probably due to the high content of water in the living matter, whose conversion to ice crystals may be associated with severe and irreversible damages. Among reproductive cells and tissues, metaphase II oocytes are notably vulnerable to cryopreservation, mainly because of their large size, low surface area to volume ratio, relatively high water content and presence of the meiotic spindle...
February 10, 2019: Acta Obstetricia et Gynecologica Scandinavica
Martin Rudnicki, Philippe van Trappen, Paul van Kesteren
We wish to thank Dr. Matsubara et al.1 for their valuable response on our Editorial that deals with the important topic whether all residents still need to learn to perform abdominal hysterectomy.2 We think that Matsubara et al. raise some interesting issues in respect to the need for mastering abdominal hysterectomy not only by endoscopically trained gynecologist but also by obstetricians. We agree that ideally, all gynecologists should be able to quickly convert to laparotomy to control a life threatening bleeding during a laparoscopic hysterectomy...
February 10, 2019: Acta Obstetricia et Gynecologica Scandinavica
Erik Kudela
I read the original research article by Jar-Allah et al. with great interest (1). They report changes of cervical cytology and its relationship to the risk of preterm delivery in singleton pregnancies in a large cohort. It is the first study that provides the essential information regarding the connection between cervical lesions and obstetrical outcomes during several decades. Higher risk of preterm delivery in high-grade cytology group may reflect the role of HPV infection and adjacent microbial environment in the pathogenesis of preterm labor...
February 10, 2019: Acta Obstetricia et Gynecologica Scandinavica
Gabriel Levin, Amihai Rottenstreich
We read the study by Bergendahl et al. recently published in this journal with great interest1 . They performed a retrospective cohort study among nulliparous women delivered by vacuum extraction at a teaching hospital and evaluated the risk for obstetric anal sphincter injury (OASIS) giving specific attention to operator related variables. While the authors interestingly address this important issue, several important points warrant further clarification. This article is protected by copyright. All rights reserved...
February 10, 2019: Acta Obstetricia et Gynecologica Scandinavica
Endah Rahmawati, Wei-Chung Vivian Yang, Chii-Ruey Tzeng
We are pleased to read the recent letter to editor by Barra and Ferrero who have been interested in our recent publication in AOGS. In that report, we demonstrated the decreased expression of Tensin 1 (TNS1) in tissue and serum of women with endometriosis after receiving gonadotropin-releasing-hormone agonist (GnRHa) treatment. In our study, we only recruited patients with ovarian endometriosis as mentioned in the material and methods section. We agree that the expression and the changes of TNS1 might be different across endometriosis subtypes such as peritoneal endometriosis and deep infiltrating endometriosis...
February 8, 2019: Acta Obstetricia et Gynecologica Scandinavica
Sjur Lehmann, Elham Baghestan, Per Engebret Børdahl, Lorentz Muller Irgens, Svein Arvid Rasmussen
INTRODUCTION: In most pregnancies after a cesarean section, a trial of labor is an option. The objective of the study was to explore trial of labor and its failure in pregnancies with medical risk conditions, in a population with a high trial of labor rate. MATERIAL AND METHODS: In a cohort study (n=57 109), using data from the Medical Birth Registry of Norway 1989-2014, women with a second delivery after a first pregnancy cesarean section were included. Preterm, multiple, and non-cephalic deliveries were excluded...
February 8, 2019: Acta Obstetricia et Gynecologica Scandinavica
Sofie Graner, Julia Mctaggart, Fanny Nordström, Emma Melander, Johan Widenberg, Helena Kopp Kallner
INTRODUCTION: The objective was to investigate the Pearl index for ectopic pregnancy in women using levonorgestrel intrauterine system (LNG-IUS) at time of conception. MATERIAL AND METHODS: This was a sub-study of a hospital based historical cohort including women with an ectopic pregnancy diagnosed in four referral hospitals in Stockholm Sweden between December 2013 and April 2017. Study participants and type of contraception at time of conception were identified through the electronic medical chart system...
February 8, 2019: Acta Obstetricia et Gynecologica Scandinavica
Gabriele Saccone, Luigi Della Corte, Giuseppe Maria Maruotti, Johanna Quist-Nelson, Antonio Raffone, Valentino De Vivo, Gennaro Esposito, Fulvio Zullo, Vincenzo Berghella
INTRODUCTION: The lowest incidence of perinatal morbidity and mortality occurs around 39-40 weeks.Therefore, some have advocated induction of uncomplicated singleton gestations once they reach full-term. The aim of the study was to evaluate the risk of cesarean delivery and any maternal and perinatal effects of a policy of induction of labor in full-term uncomplicated women with singleton gestations. MATERIAL AND METHODS: We performed an electronic search from inception of each database to August 2018...
February 5, 2019: Acta Obstetricia et Gynecologica Scandinavica
Shanna Logan, Antoinette Anazodo
Infertility associated with cancer can have significant psychological impacts to cancer patients and survivors, necessitating appropriate fertility-related psychological support. This literature review details the psychological impact of infertility in cancer patients and survivors, and discusses fertility counselling as described in current international guidelines; as either the provision of fertility information or psychosocial support. Fertility counselling has a role in assisting with fertility treatment decision-making, but also in supporting patients with the emotional distress associated with potential infertility at the time of cancer diagnosis, and infertility in survivorship...
February 5, 2019: Acta Obstetricia et Gynecologica Scandinavica
Carlos De Bonrostro Torralba, Eva Lucía Tejero Cabrejas, Blanca Mar Envid Lázaro, Maria Jesús Franco Royo, Montserrat Roca Arquillué, Jose Manuel Campillos Maza
INTRODUCTION: The aim of this study was to compare the efficacy and safety of low-dose protocol of vaginal misoprostol and vaginal dinoprostone insert for induction of labor in women with post-term pregnancies. MATERIAL AND METHODS: We designed a prospective, randomized, open-labeled, blinded for the end-point evaluators trial including women of at least 41 weeks of gestational age with uncomplicated singleton pregnancies and Bishop score lower than 6. They were randomized into dinoprostone or misoprostol groups in a 1:1 ratio...
February 5, 2019: Acta Obstetricia et Gynecologica Scandinavica
Kenny A Rodriguez-Wallberg, Anna Marklund, Frida Lundberg, Ida Wikander, Milan Milenkovic, Amandine Anastacio, Fotios Sergouniotis, Kjell Wånggren, Jeanette Ekengren, Tekla Lind, Birgit Borgström
INTRODUCTION: In Scandinavian countries, programs for fertility preservation are offered free of charge at tertiary-care university hospitals to all patients facing treatments with risk of subsequent sterility. In this prospective study we aimed to investigate trends in female patients' choices after counseling and fertility preservation outcomes during follow-up in relation to benign vs malignant indications. MATERIAL AND METHODS: Data on 1254 females including 1076 adults and 178 girls who received fertility preservation counseling for either oncologic (N=852) or benign indications (N=402) at Karolinska University Hospital, Stockholm, between 1 Oct 1998 and 1 Dec 2018 were analyzed...
February 5, 2019: Acta Obstetricia et Gynecologica Scandinavica
Richard A Anderson, David T Baird
Ovarian tissue cryopreservation has developed rapidly from its origins in experiments in sheep in the 1990s, and is now becoming recognised as a standard, rather than experimental, procedure. This review summarises the origins of the technique, and key milestones in its development since the first reported sheep pregnancy in 1994 to the first successful human pregnancy in 2004, and now to the first baby born following cryopreservation of prepubertal ovarian tissue. Many challenges remain to optimise this technique, to improve the survival of follicles within the reimplanted ovarian tissue, to improve its reproducibility and thus success rate and the lifespan of graft...
February 5, 2019: Acta Obstetricia et Gynecologica Scandinavica
Diana Grove-Laugesen, Camilla Aaskov, Eva Ebbehøj, Ulla B Knudsen
INTRODUCTION: Thyroid disorders have been associated with adverse reproductive outcome. Whether the preconceptional level of thyrotropin (TSH) in euthyroid women impacts on in vitro fertilization (IVF) outcome has been debated. This study reports the outcome of first IVF cycle in euthyroid women in relation to TSH level. MATERIAL AND METHODS: A retrospective study was conducted in women referred for fertility treatment in the period January 1, 2012 until March 31, 2014...
February 5, 2019: Acta Obstetricia et Gynecologica Scandinavica
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