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Acta Clinica Belgica

Lieselot Cool, Celine Brewaeys, Stefaan Viaene, Jana Missiaen, Michelle Lycke, Tessa Lefebvre, Laura Tack, Veerle Foulon, Hans Pottel, Philip Debruyne, Dominique Vandijck, Koen Van Eygen
OBJECTIVES: Oncological home-hospitalization (OHH) might be a patient-centred approach to deal with the increasing burden of cancer on health-care facilities and finances. Before implementation into practice, its feasibility, costs and support among stakeholders should be evaluated. The purpose of this trial was to explore patients', specialists' and general practitioners' (GPs) perspectives towards the opportunities of implementing OHH within the Belgian health-care system. METHODS: A regional cross-sectional survey study was launched in order to investigate the stakeholders' views on OHH and the current cancer care focusing on integration of primary care and continuous care...
April 19, 2019: Acta Clinica Belgica
Ivana Jurin, Irzal Hadžibegović, Ivan Durlen, Sandra Jakšić Jurinjak, Domagoj Mišković, Marko Ajduk, Helena Jerkić, Tomislav Letilović
OBJECTIVE: Stratifying patients with paroxysmal or short-term persistent atrial fibrillation (AF) who are at greater risk of developing permanent AF is challenging. Aim of our prospective study was to evaluate association of laboratory parameters (biochemistry and complete blood count (CBC)) together with standard demographic, clinical and echocardiography parameters, with AF progression. METHODS: We prospectively recruited 579 patients with AF and divided them into two groups at index hospitalization: paroxysmal or persistent (non-permanent AF), and long-term persistent or permanent AF patients (permanent AF)...
April 5, 2019: Acta Clinica Belgica
Henri Thonon, Florence Espeel, Ficart Frederic, Frédéric Thys
OBJECTIVES: Central venous catheter (CVC) implementation is now usual in emergency department. The most common complications are misplacement, bleeding, pleural perforation, thrombosis and sepsis. Forgetting a guide wire in the patient's body after catheterization is an underestimated complication of this procedure; only 76 cases are described. Even if the majority of patients remained asymptomatic, severe complications can happened even years later. This article's aim is to identify the sequence of elements that led to the event occurrence and to suggest recommendations of good practice to minimize complications related to central catheter placement...
March 30, 2019: Acta Clinica Belgica
Daniel Borsboom, Imke Matthys, Christophe Van Steenkiste
No abstract text is available yet for this article.
March 28, 2019: Acta Clinica Belgica
Dimitri Poddighe
No abstract text is available yet for this article.
March 28, 2019: Acta Clinica Belgica
Barbara Geerinckx, Rachel Hellemans, Amaryllis H Van Craenenbroeck, Sven Francque, Liesbeth De Waele, Jeroen Kerstens, Pieter-Jan Van Gaal, Bart Bracke, Peter Michielsen, Thomas Vanwolleghem
Hemodialysis-related portosystemic encephalopathy (HRPSE) is a clinical phenomenon where portosystemic encephalopathy (PSE) develops without liver dysfunction, usually caused by changes in the portosystemic blood flow related to hemodialysis. We describe the case of a 22-year old patient with a transjugular intrahepatic portosystemic shunt (TIPS) who developed HRPSE several months after initiation of hemodialysis. Despite initial therapy with laxatives and neomycin symptoms recurred. It was only after relocation of the hemodialysis catheter from the superior caval vein to the femoral vein that symptoms completely resolved...
March 28, 2019: Acta Clinica Belgica
Cemile Özsürekci, Cafer Balcı, M Cemal Kızılarslanoğlu, Hatice Çalışkan, Rana Tuna Doğrul, Gözde Şengül Ayçiçek, Fatih Sümer, Erdem Karabulut, Burcu Balam Yavuz, Mustafa Cankurtaran, Meltem Gülhan Halil
OBJECTIVES: Frailty is a geriatric syndrome which develops as a result of cumulative decline in many physiological systems and results in an increased vulnerability and risk of adverse outcomes. The Clinical Frailty Scale (CFS) was validated as a predictor of adverse outcomes in community-dwelling older people and evaluates items such as comorbidity, cognitive impairment and disability. We aimed to study the concurrent and construct validity and reliability of the 9 point CFS in Turkish Population...
March 28, 2019: Acta Clinica Belgica
Kasper Raus, Eric Mortier, Kristof Eeckloo
OBJECTIVES: Health care systems worldwide are changing and taking new forms. The old, more hierarchically oriented, model with individual institutional and bilateral interactions between primary, secondary, tertiary and quaternary care is being replaced by an integrated and dynamic network model. We aim to look at what role university hospitals will play in this future organization of health care. METHOD: In this paper, we look at the relevant literature on the history of academic medicine and university hospitals...
March 21, 2019: Acta Clinica Belgica
Azar Hadadi, Afshin Ostovar, Behnaz Edalat Noor, Mehrnaz Rasoolinejad, Mahboobeh Haji Abdolbaghi, Sahar Yousefi, Hossein Khalili, Gita Manshoori, Patricia Khashayar, Zahra Alipour, Narges Safari
OBJECTIVES: We assessed the effect of selenium and zinc supplementation on CD4 cell count and the risk of developing opportunistic infections. METHODS: In a double blind clinical trial, 146 HIV(+) patients receiving combination antiretroviral therapy with CD4(+) >200/cubic millimeter were screened for comorbidities and opportunistic infections, and randomized to receive daily selenium (200 µg), zinc (50 mg) or placebo for 6 months, before a 3-month follow-up period...
March 19, 2019: Acta Clinica Belgica
A Maertens, D Persyn, W Van Moerkercke
BACKGROUND: It is well known that Crohn's disease can involve the stomach. However, most often this upper gastrointestinal tract involvement is asymptomatic. Typically, there is involvement of the small intestine with the typical associated symptoms of Crohn's disease: abdominal cramps, diarrhoea and weight loss. METHODS: We report a case of a young woman with complaints of dyspepsia since 2 months. RESULTS: Gastroscopy revealed severe aphthous pangastritis with biopsies showing a focal active and chronic gastritis with presence of granulomas...
March 18, 2019: Acta Clinica Belgica
Joanna Rybarczyk, Charlot Versteele, Tinne Lernout, Daisy Vanrompay
Chlamydia psittaci causes psittacosis in humans, mainly in persons in contact with birds in either the setting of occupational or companion bird exposure. Infection is associated with a range of clinical manifestations from asymptomatic infection to severe atypical pneumonia and systemic disease. This paper reviews new knowledge on psittacosis, its legal and regulatory aspects and presents epidemiological data on psittacosis in Belgium. In Belgium, the number of reported positive laboratory results increased slowly since 2010, and in 2017, the number almost doubled compared to the two previous years...
March 18, 2019: Acta Clinica Belgica
Emma Bakelants, Willy Peetermans, Katrien Lagrou, Wouter Meersseman
OBJECTIVES: Hantavirus infection and leptospirosis are infectious diseases transmitted by rodents. The clinical picture is nonspecific, often involving the kidneys but other organs can be affected too. Clinical and biochemical clues to make a difference between these two entities will be described. METHODS: A retrospective analysis was performed on a database of patients presenting between January 2012 and September 2017 at the emergency department of the university hospital Leuven, Belgium...
March 18, 2019: Acta Clinica Belgica
Gwen Falony, Doris Vandeputte, Clara Caenepeel, Sara Vieira-Silva, Tanine Daryoush, Séverine Vermeire, Jeroen Raes
OBJECTIVES: The prognostic, diagnostic, and therapeutic potential of the human gut microbiota is widely recognised. However, translation of microbiome findings to clinical practice is challenging. Here, we discuss current knowledge and applications in the field. METHODS: We revisit some recent advances in the field of faecal microbiome analyses with a focus on covariate analyses and ecological interpretation. RESULTS: Population-level characterization of gut microbiota variation among healthy volunteers has allowed identifying microbiome covariates required for clinical studies...
February 27, 2019: Acta Clinica Belgica
Barbara Vandendriessche, Bruno Lapauw, Jean Marc Kaufman, Tom Fiers
OBJECTIVE: To provide insight in patterns and causes of aberrant thyroid function tests (TFT) and to propose a practical approach for clinicians. METHODS: Starting from an illustrative case report, an extensive literature search was performed, resulting in a narrative literature review. RESULTS: TFT that cannot be explained by the negative feedback principle of the hypothalamo-pituitary-thyroid axis are a challenge for every clinician. Various alternative explanations for these TFT should be considered before drawing the conclusion of thyroid disorder, since incorrect diagnosis and treatment can have severe consequences for the patient...
February 26, 2019: Acta Clinica Belgica
P Chasseur, D Blockmans, C von Frenckell, J-B Nicolas, C Regniers, F Vandergheynst
INTRODUCTION: The RAVE trial has revolutionized induction treatment of anti-neutrophil cytoplasmic antibodies (ANCA)-Associated Vasculitis (AAV)by demonstrating the non-inferiority of rituximab (RTX) compared with cyclophosphamide. OBJECTIVES: We studied AAV patients' characteristics, RTX prescription practices and efficacy in AAV induction treatment in four Belgian university hospitals. The patient population, selected according to the Belgian reimbursement criteria, was relatively homogeneous and comparable to the one of RAVE trial...
February 15, 2019: Acta Clinica Belgica
Imke Matthys, Daniel Borsboom, Sophia Steyaert, Delphine Vervloet, Kristoff Cornelis, Erik Vanderstraeten, Sébastien Kindt, Pieter Dewint, Valerie Lambrecht, Peter Sinnaeve, Christophe Van Steenkiste
Mycoplasma pneumoniae infection can present with a plethora of symptoms and result in a systemic vasculitis by activating a cascade of autoimmune reactions. In this case report, a young man without relevant past medical history was admitted to the hospital with diarrhea, abdominal pain and spiking fever. A CT-scan showed terminal ileitis. A 5-day broad spectrum antibiotic treatment (ciprofloxacin/clindamycin) did not result in any clinical improvement. On the contrary, the patient developed a cholestatic hepatitis, bilateral anterior uveitis and a dry cough...
February 15, 2019: Acta Clinica Belgica
Răzvan A Ciocan, Cristina-Sorina Cătană, Cristina Drugan, D Gherman Claudia, Andra Ciocan, Tudor C Drugan, Sorana D Bolboacă
AIM: To evaluate if smoking, quantified by the serum cotinine levels, is related to the evolution of patients with critical limb ischemia (CLI). METHOD: A pilot study was conducted on CLI patients who addressed at the Second Surgery Clinic of the Emergency County Hospital, Cluj-Napoca, Romania between November 2015 and December 2016. The sample of patients was split into two groups using the threshold of 15 ng/mL for the serum level of cotinine (low cotinine level - LCL vs...
February 11, 2019: Acta Clinica Belgica
Mike Ralki, Alaaddin Yilmaz, Jacques Vanwing, Kristof Cuppens
BACKGROUND: Angiosarcoma is a rare and aggressive tumor of vascular endothelial origin. Pulmonary metastasis can lead to potential life-threatening complications, such as bleeding and pneumothorax. METHODS: We report on a 82-year-old male with major hemoptysis, recurrent hemopneumothorax and cystic lung lesions. RESULTS: Although initial diagnostic findings were misleading, thoracoscopic exploration revealed pulmonary and pleural metastasized angiosarcoma...
February 5, 2019: Acta Clinica Belgica
C Kympers, E Tommelein, Ellen Van Leeuwen, K Boussery, M Petrovic, A Somers
OBJECTIVES: The Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3 S-) tool was recently developed as an explicit screening method to detect Potentially Inappropriate Prescribing (PIP) in the community pharmacy. We aimed to validate the GheOP3 S-tool as an effective screening method for PIP. METHODS: All patients admitted to the acute geriatric ward of the Sint-Vincentius hospital (Belgium) were consecutively screened for inclusion (≥70 years,≥5 drugs chronically)...
January 30, 2019: Acta Clinica Belgica
Qianwen He, Fei Xiao, Qinghong Yuan, Jingjing Zhang, Jia Zhan, Zongze Zhang
OBJECTIVE: Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. It is the most common cause of death among critically ill patients in non-coronary intensive care units and the incidence continues to rise. Although advanced management was applied, the prognosis of sepsis patients remains poor. As a G-protein coupled receptor, cannabinoid receptor 2 (CB2R) was implicated in a wide variety of diseases. In this study, we aimed to investigate the role of CB2R in sepsis...
April 2019: Acta Clinica Belgica
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