journal
Journals Journal of International Medic...

Journal of International Medical Research

https://read.qxmd.com/read/38613248/glycated-serum-protein-is-independently-associated-with-progressive-infarction-in-patients-with-acute-ischemic-stroke
#1
JOURNAL ARTICLE
Keji Zou, Caixia Wei, Qin Huang, Zubing Xu, Xiaocheng Mao, Hudie Zhang, Chenying Zeng, Lanjiao Zhang, Jing Lin, Yuling Yi, Jinchong Zhang
OBJECTIVE: This study investigated the relationship between glycated serum protein (GSP) and progressive infarction (PI). METHODS: From April 2017 to December 2020, we recruited 477 patients within 48 hours after the onset of acute ischemic stroke into this case-control study. Demographic characteristics, clinical information, and laboratory and neuroimaging data were recorded after admission. RESULTS: PI occurred in 144 (30.8%) patients. Patients with PI had higher initial National Institute of Health Stroke Scale (NIHSS) scores, higher discharge NIHSS scores, higher modified Rankin scale scores at 3 months after onset, higher GSP levels, lower prothrombin times, and lower creatinine levels than patients without PI...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38606757/granulomatosis-with-polyangiitis-or-its-mimic-a-case-report
#2
JOURNAL ARTICLE
Tamás Major, Gábor Nagy, Judit Szabó, Huba Mózes, Gabriella Szűcs, Zoltán Szekanecz, Szilvia Szamosi
Differentiation between granulomatosis with polyangiitis (GPA) limited to the upper airways and cocaine-induced midline destructive lesion (CIMDL) may be particularly difficult because of their common histopathologic features and antineutrophil cytoplasmic antibody (ANCA) profiles. We herein present a case involving a young woman with an initial diagnosis of GPA based on upper and lower airway manifestations and constitutional symptoms, histopathologic evidence of granulomas, a positive cytoplasmic ANCA indirect immunofluorescent test result, and proteinase 3 positivity by enzyme-linked immunosorbent assay (ELISA)...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38606755/intraventricular-haemorrhage-treated-by-extra-ventricular-drainage-with-catheter-mistakenly-penetrating-the-cisterna-ambiens-a-case-report
#3
JOURNAL ARTICLE
Liansheng Gao, Kaibo Yu, Yanfei Feng, Feng Yan, Cong Qian
Intraventricular haemorrhage (IVH) is a severe and acute type of stroke with a complex pathophysiology and is a therapeutic challenge. This case report described a man in his early 50's diagnosed with IVH by computed tomography (CT). Although bilateral extraventricular drainage (EVD) was undertaken, a postoperative CT scan showed that while the left catheter was correctly positioned, the right catheter had been wrongly inserted into the cisterna ambiens. The procedure was equivalent to simultaneous EVD combined with cisternostomy...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38606735/multiple-carcinomas-in-a-woman-with-hiv-infection-a-case-report-and-literature-review
#4
JOURNAL ARTICLE
John Adi Ashindoitiang, Victor Ikechukwu Carnice Nwagbara, Mba Okpan Ozinko, Theophilus Ipeh Ugbem, Maurice Efana Asuquo
Non-acquired immunodeficiency syndrome-defining cancers (NADCs) are malignancies in persons living with human immunodeficiency virus (PLWHIV) and are not primarily due to the host's immunodeficiency. There is renewed clinical interest in long-term morbidities in PLWHIV as well as malignancies that occur in this population. We herein describe a 36-year-old woman with a 2-year history of an anal wound and right breast mass. She had been diagnosed with HIV infection prior to the development of these lesions. Clinical and laboratory evaluations led to diagnoses of breast and anal cancers...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38606734/association-of-the-neutrophil-to-lymphocyte-ratio-with-the-occurrence-of-venous-thromboembolism-and-arterial-thrombosis
#5
JOURNAL ARTICLE
Ha Thanh Nguyen, Minh Phuong Vu, Thi Tuyet Mai Nguyen, Tuan Tung Nguyen, Thi Van Oanh Kieu, Hai Yen Duong, Phuong Thao Pham, Thi Hue Hoang
OBJECTIVE: This study aimed to assess the association of the neutrophil-to-lymphocyte ratio (NLR) with the occurrence of venous thromboembolism (VTE) and arterial thrombosis (AT). METHODS: This was a retrospective cross-sectional study including 585 medical records obtained from all consecutive patients who were suspected of having thrombosis. RESULTS: The AT group had a higher neutrophil count and NLR and a lower lymphocyte count than the non-thrombosis group...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38606733/predictors-of-cancer-specific-survival-and-overall-survival-among-patients-aged-%C3%A2-60-years-with-lung-adenocarcinoma-using-the-seer-database
#6
JOURNAL ARTICLE
Feiyang Li, Fang Li, Dong Zhao, Haowei Lu
OBJECTIVE: We developed a simple, rapid predictive model to evaluate the prognosis of older patients with lung adenocarcinoma. METHODS: Demographic characteristics and clinical information of patients with lung adenocarcinoma aged ≥60 years were retrospectively analyzed using Surveillance, Epidemiology, and End Results (SEER) data. We built nomograms of overall survival and cancer-specific survival using Cox single-factor and multi-factor regression. We used the C-index, calibration curve, receiver operating characteristic (ROC) curves, and decision curve analysis (DCA) to evaluate performance of the nomograms...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38603615/hepatic-portal-venous-gas-initially-manifesting-as-severe-shock-a-case-series
#7
JOURNAL ARTICLE
Anwei Liu, Jiao Shen, Liansheng Long, Xuezhi Shi, Qiang Wen, Zhiguo Pan
Hepatic portal venous gas is often referred to as the "sign of death" because it signifies a very poor prognosis if appropriate treatments are not promptly administered. The etiologies of hepatic portal venous gas are diverse and include severe complex abdominal infections, mesenteric ischemia, diving, and complications of endoscopic surgery, and the clinical manifestations are inconsistent among individual patients. Thus, whether emergency surgery should be performed remains controversial. In this report, we present three cases of hepatic portal venous gas...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38603613/sildenafil-improves-hemodynamic-changes-caused-by-acute-pulmonary-embolism-by-inhibiting-rho-kinase-activity
#8
JOURNAL ARTICLE
Hui Wang, Wei Li, Yan Yan, Meng-Jie Shi, Feng Hou, Rui-Peng Zhang
OBJECTIVE: This study examined the effects of sildenafil on acute pulmonary embolism (APE) using a rat model. METHODS: Sprague-Dawley rats were randomly divided into the sham, pulmonary thromboembolism (PTE), and sildenafil groups. The sham and PTE groups received normal saline once daily via gavage for 14 consecutive days, whereas the sildenafil group received sildenafil (0.5 mg/kg/day) once daily via gavage for 14 consecutive days. Autologous emboli were prepared from blood samples collected from the left femoral artery of rats in each group on day 13, and autologous emboli were injected into the jugular vein cannula of rats in the PTE and sildenafil groups on day 14...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38603608/temporomandibular-disorders-among-ehlers-danlos-syndromes-a-narrative-review
#9
JOURNAL ARTICLE
Ole Oelerich, Linda Daume, Negin Yekkalam, Marcel Hanisch, Max C Menne
This narrative review aims to demonstrate and summarize the complex relationship between Ehlers-Danlos syndromes (EDS) and temporomandibular disorders (TMD) by reviewing the results of observational studies and case reports. EDS are a set of hereditary connective tissue disorders, where generalized joint hypermobility (GJH), especially in the hypermobile subtype (hEDS), is a key symptom. Mutations have been identified in genes that impact the production or assembly of collagen for all subtypes except hEDS. While the correlation between GJH and TMD has been analysed in various studies, fewer studies have examined TMD in patients with EDS, with most showing an increased prevalence of TMD...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38603605/isolated-gastric-varices-associated-with-antiphospholipid-syndrome-and-protein-s-deficiency-a-case-report-and-review-of-the-literature
#10
JOURNAL ARTICLE
Xueyan Li, Jiandi Wu, Feifei Fang, Ying Liu, Wewei Jiang, Gangping Li, Jun Song
The mortality rate of gastric varices bleeding can reach 20% within 6 weeks. Isolated gastric varices (IGVs) refer to gastric varices without esophageal varices and typically arise as a common complication of left portal hypertension. Although IGVs commonly form in the setting of splenic vein occlusion, the combination of antiphospholipid syndrome and protein S deficiency leading to splenic vein occlusion is rare. We herein present a case of a 28-year-old woman with intermittent epigastric pain and melena. She was diagnosed with antiphospholipid syndrome based on the triad of pregnancy morbidity, unexplained venous occlusion, and positive lupus anticoagulant...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38603599/use-of-noninvasive-brain-stimulation-and-neurorehabilitation-devices-to-enhance-poststroke-recovery-review-of-the-current-evidence-and-pitfalls
#11
JOURNAL ARTICLE
Chien-Chih Wang, Tsung-Ming Hu, Yung-Jie Lin, Chien-Lung Chen, Yu-Chuan Hsu, Chung-Lan Kao
Neurorehabilitation devices and technologies are crucial for enhancing stroke recovery. These include noninvasive brain stimulation devices that provide repetitive transcranial magnetic stimulation or transcranial direct current stimulation, which can remodulate an injured brain. Technologies such as robotics, virtual reality, and telerehabilitation are suitable add-ons or complements to physical therapy. However, the appropriate application of these devices and technologies, which target specific deficits and stages, for stroke therapy must be clarified...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38597115/portal-vein-gas-is-a-sign-of-intestinal-necrosis-after-pesticide-poisoning-a-case-report
#12
JOURNAL ARTICLE
Huipeng Zhu, Guozhong Chen, Shiyi Liu, Keyan Hong, Huajun Wang
Portal vein gas accumulation and intestinal pneumatosis are uncommon signs indicating a high mortality risk in cases of intestinal ischemic necrosis. However, the widespread use of computed tomography has led to an increase in detection of benign lesions. We report a case of portal vein gas accumulation resulting from organophosphorus pesticide poisoning. A male patient was brought to the hospital in a comatose state with bilateral pupils that measured 1.0 mm, and he showed shortness of breath and wet rattles in the lungs...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38597095/an-immunocompetent-host-with-blood-disseminated-aspergillus-versicolor-spondylitis-a-case-report-and-literature-review
#13
JOURNAL ARTICLE
Shuangxia Dong, Qianding Lin, Xinjian Dai, Zhou Lin
Blood-disseminated Aspergillus spondylitis in immunocompetent individuals is rare. The clinical, imaging, and pathological manifestations of this condition are not specific. Therefore, this disease is prone to misdiagnosis and a missed diagnosis. Systemic antifungal therapy is the main treatment for Aspergillus spondylitis. We report a case of blood-disseminated Aspergillus versicolor spondylitis in a patient with normal immune function. The first antifungal treatment lasted for 4 months, but Aspergillus spondylitis recurred a few months later...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38587839/characterization-and-prevention-of-flame-burns-caused-by-electric-bicycle-battery-chargers-results-from-a-7-year-experience
#14
JOURNAL ARTICLE
Xiqiao Wang, Ming Tian, Liqiang Zheng, Liang Qiao, Yan Liu, Bo Yuan
OBJECTIVE: With the recent exponential increase in express deliveries across China, the number of patients with flame burns caused by electric bicycle battery chargers (BEBBC) has markedly increased in burn units. In this study, we aimed to characterize BEBBC to systematically explore measures to prevent their occurrence. METHODS: We performed a retrospective chart review of patients with flame burns who visited the Burn Department of Rui Jin Hospital between January 2015 and December 2021...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38587813/covid-19-induced-acute-loss-of-consciousness-in-marchiafava-bignami-disease-a-case-report
#15
JOURNAL ARTICLE
Jie Tian, Hai-Li Wang, Shuang-Jie Li, Chang-He Shi
Among the various manifestations of COVID-19, the neurological implications of SARS-CoV-2 infection are of significant concern. Marchiafava-Bignami disease (MBD), a neurodegenerative disorder, exhibits a clinical spectrum ranging from mild progressive dementia in its chronic form to states of acute coma and varied mortality rates. Acute MBD primarily occurs in chronic alcoholics and malnourished individuals and is characterized by sudden loss of consciousness, seizures, confusion, and psychosis. We herein report a case of MBD presenting as acute loss of consciousness after the development of COVID-19...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38573764/improving-accuracy-of-vascular-access-quality-classification-in-hemodialysis-patients-using-deep-learning-with-k-highest-score-feature-selection
#16
JOURNAL ARTICLE
Sarayut Julkaew, Thakerng Wongsirichot, Kasikrit Damkliang, Pornpen Sangthawan
OBJECTIVE: To develop and evaluate a novel feature selection technique, using photoplethysmography (PPG) sensors, for enhancing the performance of deep learning models in classifying vascular access quality in hemodialysis patients. METHODS: This cross-sectional study involved creating a novel feature selection method based on SelectKBest principles, specifically designed to optimize deep learning models for PPG sensor data, in hemodialysis patients. The method effectiveness was assessed by comparing the performance of multiple deep learning models using the feature selection approach versus complete feature set...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38565321/application-of-radiomics-in-ischemic-stroke
#17
REVIEW
Jie Yang, Huabo Cai, Ning Liu, Jiajie Huang, Yun Pan, Bo Zhang, Minfeng Tong, Zhongheng Zhang
In recent years, radiomics has emerged as a novel research methodology that plays a crucial role in the diagnosis and treatment of ischemic stroke. By integrating multimodal medical imaging techniques such as computed tomography and magnetic resonance imaging, radiomics offers in-depth insights into aspects such as the extent of brain tissue damage and hemodynamics. These data help physicians to accurately assess patient condition, select optimal treatment strategies, and predict recovery trajectories and long-term prognoses, thereby enhancing treatment efficacy and reducing the risk of complications...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38565223/assessing-emerging-causes-of-mitral-regurgitation-atrial-functional-mitral-regurgitation
#18
REVIEW
Francesco Nappi
Functional or secondary mitral regurgitation is linked to increased cardiovascular morbidity and mortality. From a mechanical perspective, secondary mitral regurgitation occurs due to an imbalance between the forces that tether the mitral leaflets and those that close them. This results in incomplete coaptation. Most commonly, functional mitral regurgitation, which occurs in both ischaemic and non-ischaemic disease states, is usually caused by dysfunction and changes in the left ventricle. Atrial functional mitral regurgitation (AFMR) is a disease state that has been more recently recognized...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38553028/a-retrospective-study-of-the-effects-of-uterine-manipulators-on-prognosis-in-patients-with-cervical-cancer
#19
JOURNAL ARTICLE
Xinmeng Guo, Enfeng Zhao, Zheng Guan, Weiping Li, Jinning Zhang, Shuang Tian, Yuanqing Yao
OBJECTIVE: This retrospective study investigated the effects of uterine manipulator use during minimally invasive radical hysterectomy on prognosis in patients with cervical cancer. METHODS: We collected clinical data on 762 patients with stage IA2 to IIB cervical cancer who underwent radical hysterectomy and pelvic lymphadenectomy in Chinese PLA General Hospital from 2009 to 2019. Kaplan-Meier analysis and log-rank tests were used to compare the 5-year overall survival rates between patients treated with and without a uterine manipulator...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38548473/making-causal-inferences-from-transactional-data-a-narrative-review-of-opportunities-and-challenges-when-implementing-the-target-trial-framework
#20
REVIEW
Santiago Esteban, Alejandro Szmulewicz
The target trial framework has emerged as a powerful tool for addressing causal questions in clinical practice and in public health. In the healthcare sector, where decision-making is increasingly data-driven, transactional databases, such as electronic health records (EHR) and insurance claims, present an untapped potential for answering complex causal questions. This narrative review explores the potential of the integration of the target trial framework with real-world data to enhance healthcare decision-making processes...
March 2024: Journal of International Medical Research
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