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ORL; Journal for Oto-rhino-laryngology and its related Specialties

Roee Landsberg, Meir Warman, Ariel Margulis, Muhamed Masalha
BACKGROUND: Complete removal of some maxillary sinus pathologies may be challenging. We describe our experience in performing endoscopic inferior meatal antrostomy (EIMA) when approaching certain chronic maxillary sinus disease. METHODS: Retrospectively reviewing charts of all patients whose surgery included EIMA between the years 2012 and 2015. EIMA was performed either after routine endoscopic middle meatal antrostomy (EMMA) failed to completely resect the lesion, or as the sole selected approach for specific maxillary pathologies...
February 8, 2019: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Kadriye Serife Ugur, Muradiye Acar, Duygu Ozol, Elif Dagli, Murat Oznur, Aydin Kosus, Mehmet Gunduz
BACKGROUND/AIMS: The aim of this study was to observe the relationship between the gene expression profiles of tumor necrosis factor (TNF)-α and endothelin (EDN)-1 and obstructive sleep apnea (OSA). METHODS: A prospective, cross-sectional study performed at a tertiary-care academic center; 108 patients with snoring and day-time sleeplessness were included in this study carried out in the Otolaryngology Department. All patients were evaluated with 1-night polysomnography (PSG)...
December 11, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Filippo Montevecchi, Alberto Caranti, Giovanni Cammaroto, Giuseppe Meccariello, Claudio Vicini
Eagle syndrome is a rare and poorly understood clinical condition caused by an elongated or disfigured styloid process. The possible managements of Eagle syndrome include conservative medical treatment or surgical intervention. The surgical removal of the elongated styloid process may be efficiently achieved either by an intraoral or a transcervical approach. An effective styloidectomy may be either total or partial, provided the bony residue's length is within the range of normality. Here, we report our experience with a bilateral robotic-assisted styloidectomy in a young female patient...
December 11, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Giuditta Mannelli, Francesco Arcuri, Lara Valentina Comini, Domenico Valente, Giuseppe Spinelli
OBJECTIVE: The buccal fat pad (BFP) has been progressively introduced into clinical practice for oral defect reconstruction. This study describes our experience with this technique and compares indications in the literature and outcomes. METHODS: We prospectively enrolled 24 patients presenting oral surgical defects and treated between January 2012 and January 2015 at our institution. They all were eligible for BFP defect reconstruction. A comprehensive literature review was performed from 1977 onwards and surgical indications and results were compared...
December 11, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Dunia Abdul-Aziz, Joseph Zenga, Daniel G Deschler
BACKGROUND/AIMS: The tracheoesophageal prothesis (TEP) has become the primary modality for laryngeal communication after total laryngectomy due to high success rates, minimal morbidity, and more natural pulmonary driven speech. Fibrosis, kyphosis, and post-radiation contracture may preclude TEP placement through rigid esophagoscopy, and certain patients may not tolerate an in-office awake procedure. For such patients, a technique for flexible esophageal stenting and TEP placement is necessary...
November 28, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Lana Jurlin, Tomislav Gregurić, Tomislav Baudoin, Marko Velimir Grgić, Leo Pažanin, Andro Košec, Glenis Scadding, Livije Kalogjera
PURPOSE: We aimed to evaluate the interaction between the overall severity of chronic rhinosinusitis (CRS) before treatment and subjective improvement following surgical or medical treatment. PROCEDURES: A group of 97 patients with CRS completed the visual analog scale (VAS) symptom score and the Sino-Nasal Outcome Test 22 (SNOT-22) questionnaire in the moment of their sinus computerized tomography (CT) scan. Data were analyzed via a 2-step cluster analysis based on gender, polyp presence, CT scan, and VAS scores for symptoms...
November 20, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Mohammad-Reza Mahmoudian-Sani, Mohammad Jamshidi, Samira Asgharzade
INTRODUCTION: Fibroblast growth factor, nerve growth factor neurotrophins, and insulin-like growth factor 1 are considered 3 families of growth factors that can be involved in the process of otic neurogenesis. In this respect, otic neurons can also be connected with mechanoreceptors in the ear, the hair cells (HCs), as well as the central nervous system. As a growth factor is combined with gene transfer technology, it can be used for hair cell regeneration. Gene therapy can be similarly employed to introduce genes into a system in order to induce the expression of genes for therapeutic agents, to replace defective genes, or to re-program supporting or surrounding cells to acquire the phenotype of lost or damaged cells in order to repair or regenerate the damaged tissue...
October 25, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Badr Eldin Mostafa, Talaat Ali Elsamny, Tamer Ali Youssef, Ahmed Bahaa Elserwi, Ahmed Abdelmoneim Teaima
OBJECTIVE: To define anatomical variations associated with arterial blood supply of the nose which has clinical implications on the management of different disorders, especially intractable posterior epistaxis. STUDY DESIGN: Case series. METHODS: Selective angiography of external and internal carotid arteries of 100 patients scheduled for routine angiography was done. RESULTS: Different anatomical variations were documented...
October 18, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Takahiro Saito, Kenzo Tsuzuki, Hiroki Nishikawa, Ken Okazaki, Kengo Hashimoto, Masafumi Sakagami
OBJECTIVES: We aimed to verify the usefulness of our proposed nasal symptom questionnaire (NSQ) scoring system and to determine predictors linked to the improvement in nasal symptoms in chronic rhinosinusitis (CRS) patients undergoing endoscopic sinus surgery (ESS). PATIENTS AND METHODS: Ninety-one CRS patients undergoing ESS and 144 volunteers with results of NSQ available were enrolled. The NSQ consists of 10 items. Receiver-operating-characteristic (ROC) curve, area under the ROC curve (AUC), internal consistency, and test-retest reproducibility of the NSQ were analyzed...
October 11, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Kaishi Wang, Yi Jiang, Zhifei Zhang, Yongtian Lu, Yusu Ni
OBJECTIVE: To study the clinical anatomy of the epitympanum, the attic, and its medial wall, to try to discover a new clinical operation-related anatomical landmark, and to investigate the adjacent anatomical relationship with this landmark. MATERIALS AND METHODS: Eight donor temporal bone specimens were dissected endoscopically. For 29 healthy persons (17 males and 12 females), CT images of the temporal bone (57 ears) were taken, 3-dimensional (3-D) reconstruction and multidimensional plane reconstruction were performed, and identification and assessment of 3-D spatial relationships between any 2 of these complex structures were done...
October 10, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Ayhan Kars, Bülent Aktan, Korhan Kilic, M Sedat Sakat, M Sıtkı Gözeler, Özgür Yörük, Vahit Mutlu, Sinan Yılmaz
INTRODUCTION: Thyroid cancer is the most common endocrine system cancer. Although fine-needle aspiration biopsy is the most commonly used method for diagnosis, it is not always sufficient. The aim of this study was to investigate the influence of preoperative serum thyroglobulin (Tg) concentration on differentiated thyroid cancer risk. MATERIAL AND METHODS: A total of 133 patients who underwent total thyroidectomy due to various indications at the Ear-Nose-Throat Department, Ataturk University Medical School, between April 2015 and December 2015, were included in this prospective study...
September 25, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Fei Wang, Jian-Fei Sheng, Lei Cai, Yong Xu, Hua Liao, Ze-Zhang Tao
PURPOSE: To investigate the possible telomerase and alternative lengthening of telomeres (ALT) mechanisms influencing the apoptosis of laryngeal squamous cells. MATERIALS AND METHODS: The effects of the telomerase mechanism were observed by knockdown of human telomerase reverse transcriptase (hTERT). The ALT mechanism was induced by silencing related genes including TRF2, RAD51, and NBS1. Effects of telomerase and ALT mechanisms on tumor development were confirmed by xenograft tumors model...
September 13, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Min Chen, Jian Chen, Yue Yang, Chang-Jiang Li, Hai-Tao Wu, Lei Chen
AIMS: To confirm the efficacy of conservative treatment for laryngeal contact granuloma and identify factors influencing treatment outcome. METHODS: In this prospective study, patients with laryngeal contact granuloma were divided into a group receiving conservative treatment and a group undergoing surgery. Efficacy was assessed by analyzing the complete response after a 48-week follow-up. The association of treatment outcome with clinical factors was then evaluated...
September 11, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Jie Huang, Zeqing Li, Kunmin Wu, Wuqing Wang
OBJECTIVE: This study aimed to assess long-term outcomes after performing tympanoplasty without mastoidectomy (TWOM) for active and inactive noncholesteatomatous chronic otitis media (COM) and to estimate the optimal time for surgery. METHODS: The patients were placed into an active ear group (group A) and an inactive ear group (group B). All patients were followed up for 5 years after TWOM. RESULTS: Ninety-two cases among 113 achieved dry ears in half a month to 1 month...
August 21, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Xiaoting Cheng, Bing Wang, Yangwenyi Liu, Yasheng Yuan, Yilai Shu, Bing Chen
OBJECTIVE: The objective of this study was to examine whether cochlear implantation using the round window (RW) route versus cochleostomy achieves comparable electrode impedance and hearing results. METHODS: This retrospective analysis included 40 patients receiving a cochlear implant (REZ-1): 20 using the RW approach and the remaining 20 using cochleostomy. Electrode impedance and tone, vowel, consonant, disyllable and sentence perception were measured during and after the implantation...
August 17, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Henrique Wendling Sava, Rogério Aparecido Dedivitis, Gustavo Rosa Gameiro, Elio Gilberto Pfuetzenreiter, Ricardo Camillo de Almeida, Leandro Luongo Matos, Claudio Roberto Cernea
INTRODUCTION: The anterior commissure is an area of glottic cancer infiltration, even in early stages. OBJECTIVE: To evaluate the invasion by tumors into the anterior commissure cartilage in surgical specimens of frontolateral laryngectomy. METHODS: Forty-eight patients who had undergone frontolateral laryngectomy for T1b/T2 squamous cell carcinoma were included. Epidemiological and clinical aspects as well as morphological histopathological analysis were evaluated...
August 17, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
David Schwarz, Konrad Johannes Stuermer, Jan Christoffer Luers
AIMS: The aim of the study was to evaluate different irrigation solutions during sialendoscopy to reduce complaints caused by sialodochitis. METHODS: The investigators designed and implemented a retrospective study composed of 94 patients with sialodochitis but no sialolithiasis or relevant stenosis of the salivary duct system. Three different irrigations (normal saline, cortisone single-shot, and cortisone) were used. After the sialendoscopy, the patients were asked about the current status of the affected salivary gland, and the quantity and quality of the gland swelling/inflammation over a follow-up period of 11...
August 15, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Kitti Jantharapattana, Teerapol Kotamnivates, Siriporn Hirunpat, Roongrueng Jarumanokul
PURPOSE OF STUDY: An association of squamous cell carcinoma antigen (SCC-Ag) level with cancer prognosis has been reported in many studies. Our investigators conducted the first study determining a correlation between the SCC-Ag level and the tumor volume in head and neck cancer. PROCEDURES: The SCC-Ag level of patients were measured from the serum, whilst the tumor volume was calculated by the ellipsoid formula and verified by logistic software on radiology. The correlation between SCC-Ag level and tumor volume was analyzed...
August 9, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Jose Fernando Polanski, Lucas Resende Lucinda, Thomas Linder
Imaging data provided by computed tomography scans of the temporal bone are fundamental for both the diagnosis and treatment of diseases affecting this complex structure. Despite its importance, the expertise required to analyze this exam is seldom properly acquired as it is time-consuming and often neglected among young doctors and even otolaryngologists. Physicians may not even have a look at the scans but rely only on radiology reports. Radiologists, on the other hand, may not describe the individual scans the same way as clinicians...
August 9, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Enyinnaya Ofo, Harry Spiers, Dae Kim, Umamaheswar Duvvuri
Carcinoma of unknown primary (CUP) comprises approximately 1%-5% of all head and neck malignancies. Primary site detection rates for metastatic cervical squamous cell carcinoma (SCC) remain variable, with current diagnostic imaging unable to identify all tumours. Prevailing evidence suggests that most head and neck CUP are located in the oropharynx. Diagnostic surgical efforts have been directed at sampling the entire oropharynx. Present techniques that make this possible include transoral robotic surgery (TORS)...
2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
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