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Environmental Health Perspectives

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https://read.qxmd.com/read/30998388/the-future-of-stunting-potential-scenarios-under-climate-change
#1
Charles W Schmidt
No abstract text is available yet for this article.
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30994381/linking-bisphenol-s-to-adverse-outcome-pathways-using-a-combined-text-mining-and-systems-biology-approach
#2
Jean-Charles Carvaillo, Robert Barouki, Xavier Coumoul, Karine Audouze
BACKGROUND: Available toxicity data can be optimally interpreted if they are integrated using computational approaches such as systems biology modeling. Such approaches are particularly warranted in cases where regulatory decisions have to be made rapidly. OBJECTIVES: The study aims at developing and applying a new integrative computational strategy to identify associations between bisphenol S (BPS), a substitute for bisphenol A (BPA), and components of adverse outcome pathways (AOPs)...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30990728/environmental-health-indicators-for-china-data-resources-for-chinese-environmental-public-health-tracking
#3
Jie Ban, Zonghao Du, Qing Wang, Runmei Ma, Ying Zhou, Tiantian Li
Many developed countries use environmental public health tracking to gain a better understanding of the link between environmental hazards and public health. To respond to complicated environmental health issues, the National Institute of Environmental Health (NIEH), Chinese Center for Disease Control and Prevention (China CDC), has begun to build a Chinese Environmental Public Health Tracking (CEPHT) system. On behalf of the CEPHT, authors provide insight into the CEPHT's development, current status, and future plans...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30986089/climate-change-human-health-and-social-stability-addressing-interlinkages
#4
Samuel Sellers, Kristie L Ebi, Jeremy Hess
BACKGROUND: Abundant historical evidence demonstrates how environmental changes can affect social stability and, in turn, human health. A rapidly growing body of literature, largely from political science and economics, is examining the potential for and consequences associated with social instability related to current climate change. However, comparatively little of this research incorporates the effects on human health or the role of health systems in influencing the magnitude and types of instability that could occur...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30986088/associations-between-high-temperature-heavy-rainfall-and-diarrhea-among-young-children-in-rural-tamil-nadu-india-a-prospective-cohort-study
#5
Andrew Mertens, Kalpana Balakrishnan, Padmavathi Ramaswamy, Paramasivan Rajkumar, Prabhakar Ramaprabha, Natesan Durairaj, Alan E Hubbard, Ranjiv Khush, John M Colford, Benjamin F Arnold
BACKGROUND: The effects of weather on diarrhea could influence the health impacts of climate change. Children have the highest diarrhea incidence, especially in India, where many lack safe water and sanitation. OBJECTIVES: In a prospective cohort of 1,284 children under 5 y of age from 900 households across 25 villages in rural Tamil Nadu, India, we examined whether high temperature and heavy rainfall was associated with increased all-cause diarrhea and water contamination...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30969138/the-association-between-mandated-preseason-heat-acclimatization-guidelines-and-exertional-heat-illness-during-preseason-high-school-american-football-practices
#6
Zachary Y Kerr, Johna K Register-Mihalik, Riana R Pryor, Lauren A Pierpoint, Samantha E Scarneo, William M Adams, Kristen L Kucera, Douglas J Casa, Stephen W Marshall
BACKGROUND: The risk of heat-related illness and death may continue to increase in many locations as a consequence of climate change, but information on the effectiveness of policies to protect populations from the adverse effects of excessive heat is limited. In 2009, the National Athletic Trainers' Association Inter-Association Task Force (NATA-IATF) released guidelines to reduce exertional heat illness (EHI) among U.S. high school athletes participating in preseason sports activities, including preseason practice sessions for American football...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30964323/the-carcinogenome-project-in-vitro-gene-expression-profiling-of-chemical-perturbations-to-predict-long-term-carcinogenicity
#7
Amy Li, Xiaodong Lu, Ted Natoli, Joshua Bittker, Nisha S Sipes, Aravind Subramanian, Scott Auerbach, David H Sherr, Stefano Monti
BACKGROUND: Most chemicals in commerce have not been evaluated for their carcinogenic potential. The de facto gold-standard approach to carcinogen testing adopts the 2-y rodent bioassay, a time-consuming and costly procedure. High-throughput in vitro assays are a promising alternative for addressing the limitations in carcinogen screening. OBJECTIVES: We developed a screening process for predicting chemical carcinogenicity and genotoxicity and characterizing modes of actions (MoAs) using in vitro gene expression assays...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30957526/environmental-health-sciences-in-a-translational-research-framework-more-than-benches-and-bedsides
#8
Joel D Kaufman, Cynthia L Curl
BACKGROUND: Environmental health scientists may find it challenging to fit the structure of the questions addressed in their discipline into the prevailing paradigm for translational research. OBJECTIVE: We aim to frame the translational science paradigm to address the stages of scientific discovery, knowledge acquisition, policy development, and evaluation in a manner relevant to the environmental health sciences. Our intention is to characterize differences between environmental health sciences and clinical medicine, and to orient this effort towards public health goals...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30950628/the-usual-and-some-not-so-usual-suspects-a-new-chemical-screening-method
#9
Rachel Cernansky
No abstract text is available yet for this article.
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30942615/environmental-chemicals-and-autism-a-scoping-review-of-the-human-and-animal-research
#10
Katherine E Pelch, Ashley L Bolden, Carol F Kwiatkowski
BACKGROUND: Estimates of autism prevalence have increased dramatically over the past two decades. Evidence suggests environmental factors may contribute to the etiology of the disorder. OBJECTIVES: This scoping review aimed to identify and categorize primary research and reviews on the association between prenatal and early postnatal exposure to environmental chemicals and the development of autism in epidemiological studies and rodent models of autism. METHODS: PubMed was searched through 8 February 2018...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30933541/nonanimal-models-for-acute-toxicity-evaluations-applying-data-driven-profiling-and-read-across
#11
Daniel P Russo, Judy Strickland, Agnes L Karmaus, Wenyi Wang, Sunil Shende, Thomas Hartung, Lauren M Aleksunes, Hao Zhu
BACKGROUND: Low-cost, high-throughput in vitro bioassays have potential as alternatives to animal models for toxicity testing. However, incorporating in vitro bioassays into chemical toxicity evaluations such as read-across requires significant data curation and analysis based on knowledge of relevant toxicity mechanisms, lowering the enthusiasm of using the massive amount of unstructured public data. OBJECTIVE: We aimed to develop a computational method to automatically extract useful bioassay data from a public repository (i...
April 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30920877/the-role-of-dietary-phytoestrogens-and-the-nuclear-receptor-formula-see-text-in-adipogenesis-an-in-vitro-study
#12
Julie M Hall, Heather A Powell, Lara Rajic, Kenneth S Korach
BACKGROUND: Phytoestrogens, naturally occurring plant chemicals, have long been thought to confer beneficial effects on human cardiovascular and metabolic health. However, recent epidemiological studies, have yielded conflicting outcomes, in which phytoestrogen consumption was both positively and negatively correlated with adiposity. Interestingly, several dietary phytoestrogens are known to stimulate or inhibit the activity of the peroxisome proliferator-activated receptor gamma ([Formula: see text]), a key physiological regulator of adipogenesis...
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30920876/adverse-maternal-fetal-and-postnatal-effects-of-hexafluoropropylene-oxide-dimer-acid-genx-from-oral-gestational-exposure-in-sprague-dawley-rats
#13
Justin M Conley, Christy S Lambright, Nicola Evans, Mark J Strynar, James McCord, Barry S McIntyre, Gregory S Travlos, Mary C Cardon, Elizabeth Medlock-Kakaley, Phillip C Hartig, Vickie S Wilson, L Earl Gray
BACKGROUND: Hexafluoropropylene oxide dimer acid [(HFPO-DA), GenX] is a member of the per- and polyfluoroalkyl substances (PFAS) chemical class, and elevated levels of HFPO-DA have been detected in surface water, air, and treated drinking water in the United States and Europe. OBJECTIVES: We aimed to characterize the potential maternal and postnatal toxicities of oral HFPO-DA in rats during sexual differentiation. Given that some PFAS activate peroxisome proliferator-activated receptors (PPARs), we sought to assess whether HFPO-DA affects androgen-dependent development or interferes with estrogen, androgen, or glucocorticoid receptor activity...
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30912995/where-does-fracking-wastewater-go-socioeconomic-predictors-of-class-ii-well-placement-in-ohio
#14
Lindsey Konkel
No abstract text is available yet for this article.
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30892072/the-why-and-where-of-active-travel-modeling-bike-and-foot-traffic-across-the-united-states
#15
Charles W Schmidt
No abstract text is available yet for this article.
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30875246/cardiopulmonary-effects-of-fine-particulate-matter-exposure-among-older-adults-during-wildfire-and-non-wildfire-periods-in-the-united-states-2008-2010
#16
Stephanie DeFlorio-Barker, James Crooks, Jeanette Reyes, Ana G Rappold
BACKGROUND: The effects of exposure to fine particulate matter ([Formula: see text]) during wildland fires are not well understood in comparison with [Formula: see text] exposures from other sources. OBJECTIVES: We examined the cardiopulmonary effects of short-term exposure to [Formula: see text] on smoke days in the United States to evaluate whether health effects are consistent with those during non-smoke days. METHODS: We examined cardiopulmonary hospitalizations among adults [Formula: see text] y of age, in U...
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30873851/attention-worthy-prenatal-phthalate-exposure-and-subsequent-adhd-diagnosis
#17
Julia R Barrett
No abstract text is available yet for this article.
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30870036/legitimizing-values-in-regulatory-science
#18
Manuela Fernández Pinto, Daniel J Hicks
BACKGROUND: Over the last several decades, scientists and social groups have frequently raised concerns about politicization or political interference in regulatory science. Public actors (environmentalists and industry advocates, politically aligned public figures, scientists and political commentators, in the United States as well as in other countries) across major political-regulatory controversies have expressed concerns about the inappropriate politicization of science. Although we share concerns about the politicization of science, they are frequently framed in terms of an ideal of value-free science, according to which political and economic values have no legitimate role to play in science...
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30864815/impact-of-long-term-exposure-to-wind-turbine-noise-on-redemption-of-sleep-medication-and-antidepressants-a-nationwide-cohort-study
#19
Aslak Harbo Poulsen, Ole Raaschou-Nielsen, Alfredo Peña, Andrea N Hahmann, Rikke Baastrup Nordsborg, Matthias Ketzel, Jørgen Brandt, Mette Sørensen
BACKGROUND: Noise from wind turbines (WTs) is associated with annoyance and, potentially, sleep disturbances. OBJECTIVES: Our objective was to investigate whether long-term WT noise (WTN) exposure is associated with the redemption of prescriptions for sleep medication and antidepressants. METHODS: For all Danish dwellings within a radius of [Formula: see text] heights and for 25% of randomly selected dwellings within a radius of [Formula: see text] heights, we estimated nighttime outdoor and low-frequency (LF) indoor WTN, using information on WT type and simulated hourly wind...
March 2019: Environmental Health Perspectives
https://read.qxmd.com/read/30864814/long-term-exposure-to-wind-turbine-noise-and-risk-for-myocardial-infarction-and-stroke-a-nationwide-cohort-study
#20
Aslak Harbo Poulsen, Ole Raaschou-Nielsen, Alfredo Peña, Andrea N Hahmann, Rikke Baastrup Nordsborg, Matthias Ketzel, Jørgen Brandt, Mette Sørensen
BACKGROUND: Noise from wind turbines (WTs) is reported as more annoying than traffic noise at similar levels, raising concerns as to whether WT noise (WTN) increases risk for cardiovascular disease, as observed for traffic noise. OBJECTIVES: We aimed to investigate whether long-term exposure to WTN increases risk of myocardial infarction (MI) and stroke. METHODS: We identified all Danish dwellings within a radius 20 times the height of the closest WT and 25% of the dwellings within [Formula: see text] the height of the closest WT...
March 2019: Environmental Health Perspectives
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