journal
Journals International Urology and Neph...

International Urology and Nephrology

https://read.qxmd.com/read/38498271/phosphate-is-associated-with-frailty-in-older-patients-with-chronic-kidney-disease-not-on-dialysis
#21
JOURNAL ARTICLE
Mariana P Veloso, Venceslau A Coelho, Nigar Sekercioglu, Rosa M A Moyses, Rosilene M Elias
PURPOSE: Frailty is common in older patients with chronic kidney disease (CKD) and has been considered an independent risk factor for adverse clinical outcomes in this population. CKD-associated mineral and bone metabolism (CKD-MBD) increases energy expenditure and causes malnutrition and inflammation leading to frailty. We investigated whether CKD-MBD markers and energy metabolism are associated with frailty in patients with advanced CKD on conservative management. METHODS: In this cross-sectional study, we investigated factors associated with frailty in a sample of 75 patients ≥ 65 years, with stage 4 or 5 CKD...
March 18, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38494585/research-progress-of-astragaloside-iv-in-treating-acute-kidney-injury
#22
REVIEW
Yu Liu, Youqun Huang, Dongxuan Sun, Naijing Ye, Tong Chen, Mengfan Yang, Li Zhou, Hequn Zou
Acute kidney injury (AKI) is one of the most common clinical critical illnesses, with decreased glomerular filtration rate, retention of nitrogen products, water and electrolyte disorders, and acid-base imbalance as the main clinical manifestations. Presently, there is no effective treatment for acute kidney injury, but the main treatment is to cure the primary disease, remove risk factors, maintain acid-base and water-electrolyte balance, and undergo kidney replacement. However, the mortality rate is still high...
March 18, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38494584/can-urinary-caspase-3-and-cytochrome-c-levels-be-used-as-predictive-biomarkers-in-the-management-of-unilateral-antenatal-hydronephrosis
#23
JOURNAL ARTICLE
Seyide Görkem Zeybek, İsmail Selvi, Tayfun Oktar, M İrfan Dönmez, Orhan Ziylan, Şule Seçkin, Canan Küçükgergin
PURPOSE: We aimed to investigate the urinary caspase-3 and cytochrome c levels in patients with unilateral antenatal hydronephrosis and to determine whether changes in urinary biomarker levels could be useful for both predicting the need for surgical intervention due to ureteropelvic junction obstruction (UPJO) and postoperative surgical success. METHODS: Sixty-five children with a history of unilateral antenatal hydronephrosis and postnatal anteroposterior diameter ≥ 10 mm were included in this prospective case-control study between January 2013 and December 2021...
March 18, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38493415/causal-association-between-cardiovascular-proteins-and-membranous-nephropathy-a-bidirectional-mendelian-randomization
#24
JOURNAL ARTICLE
Qiqi Ma, Gaosi Xu
PURPOSE: Multiple circulating proteins have been reported to participate in human diseases. However, the association between cardiovascular proteins and membranous nephropathy (MN) remained profoundly elusive. METHODS: A bidirectional Mendelian randomization (MR) analysis was conducted to explore the causal correlation between ninety cardiovascular proteins and MN. Genome-wide association study (GWAS) data of cardiovascular proteins and MN were all from European research...
March 17, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38493414/computed-tomography-cannot-see-sarcopenic-obesity
#25
LETTER
Ahmad J Abdulsalam, Pelin Analay, Murat Kara
No abstract text is available yet for this article.
March 17, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38493270/ykl-40-chitinase-3-like-protein-1-serum-levels-are-associated-with-abdominal-aortic-calcification-in-hemodialysis-patients
#26
JOURNAL ARTICLE
Shu-Hong Bi, Chunyan Su, La-Ta A, Yue Wang, Lian He, Ai-Hua Zhang
BACKGROUND: Vascular calcification (VC) is highly prevalent and predicts cardiovascular mortality in dialysis patients. The mechanisms are still unclear. Inflammation is a well-known inducer of VC. YKL-40 has been suggested as a novel biomarker of inflammation and has been demonstrated to be associated with cardiovascular mortality in hemodialysis patients. This study aims to evaluate the relationship between serum YKL-40 and VC in hemodialysis (HD) patients. METHODS: A total of 109 HD patients and 31 healthy controls were enrolled in the study from September 2014 to December 2014...
March 16, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38489144/actively-extracting-kidney-stones-combined-dusting-technique-can-improve-sfr-of-moderate-complexity-kidney-stones-in-furl
#27
JOURNAL ARTICLE
Deng Li, Lei Chen, Xiaolu Lun, Chaoliang Xu, Kai Wang, Xiaolong Wang, Yuhang Bi, Jun Lu, Shujie Xia, Yongchuan Wang, Yi Shao
PURPOSE: To evaluate the necessity and effectiveness of actively extracting kidney stones with different complexity that have been visually dusted in flexible ureteroscopic lithotripsy (fURL). METHODS: We retrospectively reviewed the medical records of patients who underwent fURL with dusting technique in established hospitals. A total of 535 cases were divided into the dusting group or the dusting plus basketing group according to the use of stone basket. Their characteristics and operative parameters were collected and analyzed...
March 15, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38489143/clinical-effect-of-roxadustat-vs-erythropoietin-in-non-dialysis-ckd-with-diabetes-a-single-center-propensity-score-matching-analysis
#28
JOURNAL ARTICLE
Chen Jin, Yan Ren, Minmin Wang, Xiao Hu, Yiwei Shang, Yiwen Li, Bin Zhu, Qiang He, Lina Shao
PURPOSE: Renal anemia is a common complication of chronic kidney disease. Currently, recombinant human erythropoietin and roxadustat are the main treatments. In China, diabetic kidney disease is the primary cause of chronic kidney disease. However, high-quality evidence on the efficacy of roxadustat in patients with non-dialysis-dependent chronic kidney disease and diabetes mellitus is scarce. This study aimed to assess the clinical effect of roxadustat in such patients. METHODS: Patients with non-dialysis-dependent anemia and diabetes mellitus who received roxadustat or recombinant human erythropoietin for ≥ 4 weeks were enrolled...
March 15, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38483736/expression-and-significance-of-sirt6-in-human-peritoneal-dialysis-effluents-and-peritoneal-mesothelial-cells
#29
JOURNAL ARTICLE
Shuai-Shuai Shi, Yi-Qiang Zhang, Lu-Qi Zhang, Yun-Feng Li, Xiao-Shuang Zhou, Rong-Shan Li
Sirtuin 6 (SIRT6) can inhibit the fibrosis of many organs. However, the relationship between SIRT6 and peritoneal fibrosis (PF) in peritoneal dialysis (PD) remains unclear. We collected 110 PD patients with a duration of PD for more than 3 months and studied the influence of PD duration and history of peritonitis on SIRT6 levels in PD effluents (PDEs). We also analyzed the relationship between SIRT6 levels in PDEs and transforming growth factor beta 1 (TGF-β1), IL-6, PD duration, peritoneal function, PD ultrafiltration (UF), and glucose exposure...
March 14, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38483735/effect-of-exercise-based-rehabilitation-on-functional-capacity-and-renal-function-in-type-2-diabetes-mellitus-with-nephropathy-a-randomized-controlled-trial
#30
JOURNAL ARTICLE
Megha Nataraj, G Arun Maiya, Shankar Prasad Nagaraju, B A Shastry, K N Shivashankara, Sahana Shetty, Shreemathi S Mayya
INTRODUCTION: Diabetic nephropathy is a growing public health challenge with implications on health. Renal function decline impacts the functional ability and overall health and well-being of individuals with diabetic nephropathy due to development of several renal manifestations. The objective of the study was to determine the effect of an exercise-based rehabilitation program on functional capacity and renal function among individuals with type 2 diabetic nephropathy. METHODS: A total of 283 individuals were screened and 60 eligible participants aged 45-70 years with diabetic nephropathy were randomly allocated (n = 30 each) to the intervention group (IG) and control group (CG), respectively...
March 14, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38480602/comparison-of-temperature-and-renal-tissue-thermal-damage-by-holmium-laser-with-different-energy-parameters-during-lithotripsy-in-vitro-porcine-kidney-model
#31
JOURNAL ARTICLE
Wei Wei, Ming Chen, Le Xie, Yuan Mai, Huacai Zhu, Zhanping Xu
OBJECTIVE: Holmium laser percutaneous nephrolithotripsy was simulated by porcine kidney calculus model in vitro to investigate thermal damage of renal tissue by different energy parameters of the holmium laser. METHODS: We placed human kidney calculus specimen in fresh vitro porcine kidney, then insert thermocouple temperature probes into the submucosa of the renal pelvis and reheated in a 37 °C water bath. A percutaneous nephrological sheath was used to penetrate the renal parenchyma with a moderate irrigation rate of 30 ml/min at 18 ℃...
March 14, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38472623/associations-between-serum-testosterone-levels-and-overactive-bladder-in-women-a-cross-sectional-research-of-nhanes-2011-to-2016
#32
JOURNAL ARTICLE
Wenshuang Li, Junlong Huang, Jialiang Chen, Chi Zhang, Ruixiang Luo, Bolong Liu, Xiangfu Zhou
PURPOSE: Androgen receptors are expressed in the pelvic floor and lower urinary tract. However, the association between serum testosterone and overactive bladder (OAB) in women remains unclear. This study aimed to investigate their association in a nationally representative population. METHODS: In this cross-sectional study, we collected data on female participants older than 20 years with serum total testosterone measurements and OAB questionnaires from the 2011-2016 National Health and Nutrition Examination Survey (NHANES)...
March 12, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38466510/comparison-of-the-applicability-of-seven-calculation-equations-of-glomerular-filtration-rate-among-elderly-people-in-china
#33
JOURNAL ARTICLE
Weiwei Zhu, Yingyu Zhang, Shutao Chen, Yang Sui, Xufang Wang, Wei Li, Chenxia Juan, Yan Zhou, Kun Gao
BACKGROUND: At present, estimated glomerular filtration rate (eGFR) remains the most frequently utilized parameter in the evaluation of kidney injury severity. Numerous equations have been formulated based on serum creatinine (Scr) or serum cystatin C (Cysc) levels. However, there is a lack of consensus regarding the efficacy of these equations in assessing eGFR, particularly for elderly individuals in China. This study aimed to evaluate the applicability of the MDRD, MDRDc, CKD-EPI series, BIS1, and FAS equations within the Chinese elderly population...
March 11, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38457017/effect-of-different-alpha-receptor-antagonists-on-metabolic-parameters-a-head-to-head-comparison
#34
JOURNAL ARTICLE
Lütfullah Caştur, Mehmet Uzunlulu, Erhan Eken, Muhammed Çiçek, Ahmet Tahra, Özgür Efiloğlu, Bekir Demirtaş, Asıf Yıldırım
PURPOSE: Although it is known that alpha-adrenergic receptor antagonists have positive effects on metabolic parameters such as glucose metabolism, lipid profile, and insulin sensitivity, it is unclear whether this is a class effect. Tamsulosin is reported to have adverse effects on glucose metabolism and insulin resistance, and this may be because of its lack of glycolysis-enhancing effect compared with other alpha-adrenergic receptor antagonists with glycolysis-enhancing effects such as doxazosin, terazosin, and alfuzosin...
March 8, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38451431/effects-of-early-recovery-of-renal-function-on-adverse-renal-outcomes-and-mortality-in-patients-with-acute-kidney-injury-a-systematic-review-and-meta-analysis
#35
JOURNAL ARTICLE
Yaling Bai, Yajing Li, JingJing Jin, Meijuan Cheng, Shenglei Zhang, Xinyue Yang, Jinsheng Xu
AIM: This study intended to scrutinize the effect of RFR time on adverse renal outcomes and mortality and try to define the cutoff of early RFR. METHODS: We conducted a literature search from database inception to February 2023. Outcome measures incorporated the progression of CKD, delivery of RRT, incidence of composite renal outcomes, and mortality. And pooled results were depicted as odds ratio (OR) and 95% confidence interval (CI). RESULTS: A total of 11 studies were finally selected (507,989 patients, mean follow-up, 3...
March 7, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38448785/antimicrobial-prophylaxis-protocol-based-on-rectal-swab-culture-before-prostate-biopsy-to-prevent-infectious-complications-a-prospective-randomized-comparative-study
#36
JOURNAL ARTICLE
A Bouzouita, A Rehaiem, A Saadi, S Zaghbib, M Chakroun, H Ayed, A Ferjani, A Derouiche, I Boutiba-Ben Boubaker, M R Ben Slama
PURPOSE: To evaluate the benefit of targeted antibiotic prophylaxis (TAP) based on rectal swab culture in comparison with standard empiric antimicrobial prophylaxis in patients undergoing transrectal ultrasound-guided needle biopsy of the prostate (TRUS-BP), as well as to assess rate of fecal carriage of Fluoroquinolone-resistant Enterobacterales FQRE. PATIENTS AND METHODS: We prospectively analyzed data that randomized 157 patients within two groups: (G1) TAP according to rectal swab performed 10 days before PB; (G2): empirical antibiotic prophylaxis with ciprofloxacin...
March 7, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38446246/interdialytic-weight-gain-and-low-dialysate-sodium-concentration-in-patients-on-chronic-hemodialysis-a-systematic-review-and-meta-analysis
#37
REVIEW
Maurizio Bossola, Ilaria Mariani, Monica Sacco, Manuela Antocicco, Gilda Pepe, Enrico Di Stasio
PURPOSE: The present systematic review and meta-analysis aimed at evaluating the effect of low dialysate sodium concentration on interdialytic weight gain (IDWG) in chronic hemodialysis patients. METHODS: Studies were eligible for inclusion if they were English language papers published in a peer-reviewed journal and met the following inclusion criteria: (1) studies in adult patients (over 18 years of age), (2) included patients on chronic hemodialysis since at least 6 months; (3) compared standard (138-140 mmol/l) or high (> 140 mmol/l) dialysate sodium concentration with low (< 138 mmol/l) dialysate sodium concentration; (4) Included one outcome of interest: interdialytic weight gain...
March 6, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38441870/comparison-of-immediate-start-peritoneal-dialysis-without-break-in-period-and-conventional-start-peritoneal-dialysis-a-two-center-retrospective-audit
#38
JOURNAL ARTICLE
Suwikran Wongpraphairot, Kitjapong Choopun, Tharinee Sriphatphiriyakun, Apiradee Titawatanakul, Virasakdi Chongsuvivatwong, Atthaphong Phongphithakchai
PURPOSE: Immediate-start peritoneal dialysis (PD) has emerged as a strategy for patients in need of urgent dialysis. However, the ideal timing for initiating this procedure remains uncertain. In this study, we aimed to compare complications and outcomes between immediate-start PD and conventional-start PD. METHODS: We performed a two-center retrospective cohort study between 1 January 2015 and 31 May 2020. Patients who underwent PD were divided into immediate-start PD (without break-in period) and conventional-start PD group (break-in period within at least 14 days)...
March 5, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38441869/the-effect-of-urgent-start-peritoneal-dialysis-and-urgent-start-hemodialysis-on-clinical-outcomes-in-patients-with-chronic-kidney-disease-an-updated-systematic-review-and-meta-analysis
#39
REVIEW
Peixin Duan, Hailuo Zhang, Yun Zhang
OBJECTIVE: Recently, urgent-start peritoneal dialysis (PD) has been suggested in place of urgent-start hemodialysis (HD) in cases of chronic kidney disease (CKD). However, the comparative effectiveness of these methods is still unclear. This study compared the outcomes of urgent-start PD and urgent-start HD in CKD patients. METHODS: Electronic searches were conducted in PubMed, EMbase, Google Scholar databases, and Cochrane Library, up to 30th July 2023 for studies reporting data on all-cause mortality...
March 5, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38441868/blunted-cerebral-hemodynamic-responses-to-incremental-exercise-in-patients-with-end-stage-renal-disease
#40
JOURNAL ARTICLE
Amal Machfer, Mohamed Amine Bouzid, Nadia Fekih, Hayfa Ben Haj Hassen, Hassen Ibn Hadj Amor, Sèmah Tagougui, Hamdi Chtourou
PURPOSE: The aims of this study were to compare cerebral hemodynamics and maximal oxygen uptake (VO2peak ) in patients with end-stage renal disease (ESRD) vs. age-matched healthy controls during maximal exercise. METHODS: Twelve patients with ESRD and twelve healthy adults (CTR group) performed exhaustive incremental exercise test. Throughout the exercise test, near-infrared spectroscopy allowed the investigation of changes in oxyhemoglobin (∆O2 Hb), deoxyhemoglobin (∆HHb), and total hemoglobin (∆THb) in the prefrontal cortex...
March 5, 2024: International Urology and Nephrology
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