Alexander S Hines, Nessa A Mohandesi, Julia S Lehman, Matthew J Koster, Hafsa M Cantwell, Afsaneh Alavi, Kenneth J Warrington, Abhishek A Mangaonkar, Ronald S Go, Mrinal M Patnaik, Julio C Sartori-Valinotti
BACKGROUND: VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is an autoinflammatory disease with frequent cutaneous manifestations. METHODS: We conducted a retrospective study of all patients with genetically confirmed VEXAS syndrome seen at our institution. Available clinical photographs and skin biopsy slides were reviewed. RESULTS: Cutaneous manifestations developed in 22/25 (88%) patients with VEXAS syndrome. From this group, 10/22 (45%) developed skin involvement before or at the time of other clinical features of VEXAS...
March 8, 2023: International Journal of Dermatology