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Journals Stroke; a Journal of Cerebral ...

Stroke; a Journal of Cerebral Circulation

https://read.qxmd.com/read/38606554/orolingual-angioedema-in-stroke-without-r-tpa-treatment-evidence-for-insular-and-opercular-contribution
#1
JOURNAL ARTICLE
Ralph Werner, Johannes C Wöhrle
No abstract text is available yet for this article.
April 12, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38591228/global-regional-and-national-burdens-of-stroke-in-children-and-adolescents-from-1990-to-2019-a-population-based-study
#2
JOURNAL ARTICLE
Hao Sun, Bing Ma, Chenye Jin, Zhenning Li, Xinying Song, Yifan Bu, Tingting Liu, Xu Han, Xue Yang, Kaijie Yang, Dongchu Xu, Jing Zhang, Yongze Li
BACKGROUND: Stroke is one of the leading causes of death among children, yet evidence on stroke incidence and prognosis in this population is largely neglected worldwide. The aim of this study was to estimate the latest burden of childhood stroke, as well as trends, risk factors, and inequalities from 1990 to 2019, at the global, regional, and national levels. METHODS: The Global Burden of Disease 2019 study was utilized to evaluate the prevalence, incidence, years lived with disability, years of life lost (YLLs), and average annual percentage changes in stroke among populations aged 0 to 19 years from 1990 to 2019...
April 9, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38591222/exploring-genetic-associations-of-3-types-of-risk-factors-with-ischemic-stroke-an-integrated-bioinformatics-study
#3
JOURNAL ARTICLE
Yi Liu, Weili Wang, Xin Cui, Jian Lyu, Yanming Xie
BACKGROUND: Ischemic stroke (IS) is a major cause of disability and mortality worldwide. Increasing evidence suggests a strong association between blood pressure, blood glucose, circulating lipids, and IS. Nonetheless, the genetic association of these 3 risk factors with IS remains elusive. METHODS: We screened genetic instruments related to blood pressure, blood glucose, and circulating lipids and paired them with IS genome-wide association study data to conduct Mendelian randomization analysis...
April 9, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38586955/limb-occlusion-of-p1-posterior-cerebral-artery-fenestration-as-a-cause-of-stroke
#4
JOURNAL ARTICLE
Marialuisa Zedde, Claudio Moratti, Giovanna Di Cecco, Franco Valzania, Rosario Pascarella
No abstract text is available yet for this article.
April 8, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38577797/postcarotid-endarterectomy-reperfusion-injury-and-hemorrhage
#5
JOURNAL ARTICLE
Amanda Opaskar, Berje Shammassian, Bassam Yaghmoor, Sophia Sundararajan
No abstract text is available yet for this article.
April 5, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572663/genetically-determined-plasma-hepatocyte-growth-factor-levels-are-associated-with-the-risk-and-prognosis-of-ischemic-stroke
#6
JOURNAL ARTICLE
Qingyun Xu, Daoxia Guo, Mengyao Shi, Yinan Wang, Pinni Yang, Yiming Jia, Lulu Sun, Yi Liu, Xinyue Chang, Yu He, Li Hui, Yonghong Zhang, Zhengbao Zhu
BACKGROUND: Observational studies suggest that hepatocyte growth factor (HGF) is associated with the risk and prognosis of ischemic stroke, but the causality of these associations remains unclear. Therefore, we conducted Mendelian randomization (MR) analyses to explore the associations of genetically determined plasma HGF levels with the risk and prognosis of ischemic stroke. METHODS: A total of 13 single-nucleotide polymorphisms associated with plasma HGF were selected as genetic instruments based on the data from a genome-wide association study with 21 758 European participants...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572660/near-infrared-ii-photobiomodulation-preconditioning-ameliorates-stroke-injury-via-phosphorylation-of-enos
#7
JOURNAL ARTICLE
Shinya Yokomizo, Timo Kopp, Malte Roessing, Atsuyo Morita, Seeun Lee, Suin Cho, Emiyu Ogawa, Eri Komai, Kazumasa Inoue, Masahiro Fukushi, Susanne Feil, Hyung-Hwan Kim, Denis E Bragin, Dmitry Gerashchenko, Paul L Huang, Satoshi Kashiwagi, Dmitriy N Atochin
BACKGROUND: The current management of patients with stroke with intravenous thrombolysis and endovascular thrombectomy is effective only when it is timely performed on an appropriately selected but minor fraction of patients. The development of novel adjunctive therapy is highly desired to reduce morbidity and mortality with stroke. Since endothelial dysfunction is implicated in the pathogenesis of stroke and is featured with suppressed endothelial nitric oxide synthase (eNOS) with concomitant nitric oxide deficiency, restoring endothelial nitric oxide represents a promising approach to treating stroke injury...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572656/mechanism-of-action-and-translational-potential-of-s-meclizine-in-preemptive-prophylaxis-against-stroke
#8
JOURNAL ARTICLE
Jeong Hyun Lee, Vishal M Gohil, Pedram Heidari, Jessica L Seidel, Mohammad Zulkifli, Ying Wei, Yuhua Ji, Ali Daneshmand, Umar Mahmood, Clary B Clish, Vamsi K Mootha, Cenk Ayata
BACKGROUND: Mild chemical inhibition of mitochondrial respiration can confer resilience against a subsequent stroke or myocardial infarction, also known as preconditioning. However, the lack of chemicals that can safely inhibit mitochondrial respiration has impeded the clinical translation of the preconditioning concept. We previously showed that meclizine, an over-the-counter antivertigo drug, can toggle metabolism from mitochondrial respiration toward glycolysis and protect against ischemia-reperfusion injury in the brain, heart, and kidney...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572651/uncommon-causes-of-nontraumatic-intracerebral-hemorrhage
#9
REVIEW
Hugo Tartarin, Andrea Morotti, Ellis S Van Etten, Moran Hausman-Kedem, Andreas Charidimou, Eric Jouvent, Sophie Susen, Charlotte Cordonnier, Marco Pasi, Grégoire Boulouis
Nontraumatic intracerebral hemorrhage is an important health issue. Although common causes such as hypertension and cerebral amyloid angiopathy predominantly affect the elderly, there exists a spectrum of uncommon etiologies that contribute to the overall incidence of intracerebral hemorrhage. The identification of these rare causes is essential for targeted clinical management, informed prognostication, and strategic secondary prevention where relevant. This topical review explores the uncommon intracerebral hemorrhage causes and provides practical clues for their clinical and imaging identification...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572636/outcomes-of-decompressive-surgery-for-patients-with-severe-cerebral-venous-thrombosis-decompress2-observational-study
#10
JOURNAL ARTICLE
Sanjit Aaron, Jorge M Ferreira, Jonathan M Coutinho, Patrícia Canhão, Adriana B Conforto, Antonio Arauz, Marta Carvalho, Jaime Masjuan, Vijay K Sharma, Jukka Putaala, Maarten Uyttenboogaart, David J Werring, Rodrigo Bazan, Sandeep Mohindra, Jochen Weber, Bert A Coert, Prabhu Kirubakaran, Mayte Sanchez van Kammen, Pankaj Singh, Diana Aguiar de Sousa, José M Ferro
BACKGROUND: Decompressive neurosurgery is recommended for patients with cerebral venous thrombosis (CVT) who have large parenchymal lesions and impending brain herniation. This recommendation is based on limited evidence. We report long-term outcomes of patients with CVT treated by decompressive neurosurgery in an international cohort. METHODS: DECOMPRESS2 (Decompressive Surgery for Patients With Cerebral Venous Thrombosis, Part 2) was a prospective, international cohort study...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572635/thrombectomy-in-patients-with-ischemic-stroke-without-salvageable-tissue-on-ct-perfusion
#11
JOURNAL ARTICLE
Gabriel Broocks, Rosalie V McDonough, Matthias Bechstein, Susan Klapproth, Tobias D Faizy, Gerhard Schön, Helge C Kniep, Maxim Bester, Uta Hanning, André Kemmling, Kamil Zeleñák, Jens Fiehler, Lukas Meyer
BACKGROUND: Computed tomography perfusion (CTP) imaging is regularly used to guide patient selection for mechanical thrombectomy (MT). However, the effect of MT in patients without salvageable tissue on CTP has not been investigated. The purpose of this study was to assess the effect of MT in patients with stroke without perfusion mismatch profiles. METHODS: This observational study analyzed patients with ischemic stroke consecutively treated between March 1, 2015, and January 31, 2022, triaged by multimodal-computed tomography undergoing MT...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572634/ldl-c-lowering-ischemic-stroke-and-small-vessel-disease-brain-imaging-biomarkers-a-mendelian-randomization-study
#12
JOURNAL ARTICLE
Marie-Joe Dib, Loukas Zagkos, Devendra Meena, Stephen Burgess, Julio A Chirinos, Dipender Gill
BACKGROUND: The effects of lipid-lowering drug targets on different ischemic stroke subtypes are not fully understood. We aimed to explore the mechanisms by which lipid-lowering drug targets differentially affect the risk of ischemic stroke subtypes and their underlying pathophysiology. METHODS: Using a 2-sample Mendelian randomization approach, we assessed the effects of genetically proxied low-density lipoprotein cholesterol (LDL-c) and 3 clinically approved LDL-lowering drugs (HMGCR [3-hydroxy-3-methylglutaryl-CoA reductase], PCSK9 [proprotein convertase subtilisin/kexin type 9], and NPC1L1 [Niemann-Pick C1-Like 1]) on stroke subtypes and brain imaging biomarkers associated with small vessel stroke (SVS), including white matter hyperintensity volume and perivascular spaces...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38572633/does-reperfusion-benefit-patients-without-perfusion-mismatch
#13
EDITORIAL
Amrou Sarraj, Bruce C V Campbell
No abstract text is available yet for this article.
April 4, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38567535/risk-of-recurrent-stroke-and-mortality-among-black-and-white-patients-with-poststroke-depression
#14
JOURNAL ARTICLE
Jack Gomberg, Laura K Stein, Mandip S Dhamoon
BACKGROUND: Poststroke depression (PSD) is a treatable and common complication of stroke that is underdiagnosed and undertreated in minority populations. We compared outcomes of Black and White patients with PSD in the United States to assess whether race is independently associated with the risk of recurrent stroke and mortality. METHODS: We used deidentified Medicare data from inpatient, outpatient, and subacute nursing facilities for Black and White US patients from January 1, 2016, to December 31, 2019, to perform this retrospective cohort analysis...
April 3, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38567531/incidence-and-outcomes-of-posterior-circulation-involvement-in-moyamoya-disease
#15
JOURNAL ARTICLE
Seth S Tigchelaar, Allan R Wang, Silvia D Vaca, Yiping Li, Gary K Steinberg
BACKGROUND: Moyamoya disease (MMD) is a progressive, occlusive disease of the internal carotid arteries and their proximal branches, with the subsequent development of an abnormal vascular network that is rupture-prone. Steno-occlusive changes in the posterior cerebral arteries (PCAs) may contribute to worsened outcomes in patients with MMD; however, there is little information on the incidence and natural history of posterior circulation MMD (PCMMD). We describe clinical PCMMD characteristics in a large cohort of patients with MMD...
April 3, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38567501/caring-for-stroke-survivors-ethnic-differences-in-informal-caregiver-needs-among-mexican-american-and-non-hispanic-white-communities
#16
JOURNAL ARTICLE
Roshanak Mehdipanah, Lewis B Morgenstern, Janet Prvu Bettger, Madeline Kwicklis, Erin Case, Elizabeth Almendarez, Lynda D Lisabeth
BACKGROUND: After stroke, Mexican American (MA) individuals have worse 90-day neurological, functional, cognitive, and quality of life outcomes and a higher prevalence of poststroke depression compared with non-Hispanic White (NHW) individuals. MA individuals receive more help through informal, unpaid caregiving than NHW individuals. We examined ethnic differences in needs identified by MA and NHW stroke caregivers. METHODS: Caregivers were identified from the population-based BASIC study (Brain Attack Surveillance in Corpus Christi) in Nueces County, Texas from October 2019 to November 2021...
April 3, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38557155/exploring-the-inclusion-of-person-centered-care-domains-in-stroke-transitions-of-care-interventions-a-scientific-statement-from-the-american-heart-association
#17
REVIEW
Michelle L A Nelson, Evan MacEachern, Janet Prvu Bettger, Michelle Camicia, James J García, Moira K Kapral, Claranne Mathiesen, Jill I Cameron
BACKGROUND: Health care teams along the stroke recovery continuum have a responsibility to support care transitions and return to the community. Ideally, individualized care will consider patient and family preferences, best available evidence, and health care professional input. Person-centered care can improve patient-practitioner interactions through shared decision-making in which health professionals and institutions are sensitive to those for whom they provide care. However, it is unclear how the concepts of person-centered care have been described in reports of stroke transitional care interventions...
April 1, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38551086/brain-health
#18
JOURNAL ARTICLE
Tatjana Rundek, Jose G Romano
No abstract text is available yet for this article.
March 29, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38545798/prerisk-a-personalized-artificial-intelligence-based-and-statistically-based-stroke-recurrence-predictor-for-recurrent-stroke
#19
JOURNAL ARTICLE
Giorgio Colangelo, Marc Ribo, Estefanía Montiel, Didier Dominguez, Marta Olivé-Gadea, Marian Muchada, Álvaro Garcia-Tornel, Manuel Requena, Jorge Pagola, Jesús Juega, David Rodriguez-Luna, Noelia Rodriguez-Villatoro, Federica Rizzo, Belén Taborda, Carlos A Molina, Marta Rubiera
BACKGROUND: Predicting stroke recurrence for individual patients is difficult, but individualized prediction may improve stroke survivors' engagement in self-care. We developed PRERISK: a statistical and machine learning classifier to predict individual risk of stroke recurrence. METHODS: We analyzed clinical and socioeconomic data from a prospectively collected public health care-based data set of 41 975 patients admitted with stroke diagnosis in 88 public health centers over 6 years (2014-2020) in Catalonia-Spain...
March 28, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38545785/10-things-you-should-know-about-cerebral-small-vessel-disease
#20
JOURNAL ARTICLE
MerryJean Losso, Jia-Yi Wang, Mitch Wilson
No abstract text is available yet for this article.
March 28, 2024: Stroke; a Journal of Cerebral Circulation
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