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Stroke; a Journal of Cerebral Circulation

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https://read.qxmd.com/read/30890116/machine-learning-based-model-for-prediction-of-outcomes-in-acute-stroke
#1
JoonNyung Heo, Jihoon G Yoon, Hyungjong Park, Young Dae Kim, Hyo Suk Nam, Ji Hoe Heo
Background and Purpose- The prediction of long-term outcomes in ischemic stroke patients may be useful in treatment decisions. Machine learning techniques are being increasingly adapted for use in the medical field because of their high accuracy. This study investigated the applicability of machine learning techniques to predict long-term outcomes in ischemic stroke patients. Methods- This was a retrospective study using a prospective cohort that enrolled patients with acute ischemic stroke. Favorable outcome was defined as modified Rankin Scale score 0, 1, or 2 at 3 months...
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890115/lack-of-consensus-among-stroke-experts-on-the-optimal-management-of-patients-with-acute-tandem-occlusion
#2
Gregory Jacquin, Alexandre Y Poppe, Marilyn Labrie, Nicole Daneault, Yan Deschaintre, Laura C Gioia, Celine Odier, Jean Raymond, Daniel Roy, Alain Weill, Christian Stapf
Background and Purpose- In patients with acute stroke caused by tandem occlusion, the benefit of immediate revascularization (stenting) of the cervical internal carotid artery lesion during endovascular thrombectomy is uncertain. We sought to determine current practice patterns and whether consensus existed among physicians with stroke expertise. Methods- We distributed an online survey to stroke experts affiliated with the Canadian Stroke Consortium, the Canadian Interventional Neuro Group, the Society of Vascular and Interventional Neurology, and international ESCAPE trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) collaborators...
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890114/letter-by-qin-and-li-regarding-article-high-variability-in-neuronal-loss
#3
LETTER
Xiaoming Qin, Shize Li
No abstract text is available yet for this article.
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890113/letter-by-reale-et-al-regarding-article-hemodynamic-markers-in-the-anterior-circulation-as-predictors-of-recurrent-stroke-in-patients-with-intracranial-stenosis
#4
LETTER
Giuseppe Reale, Silvia Giovannini, Pietro Caliandro
No abstract text is available yet for this article.
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890112/mitophagy-reduces-oxidative-stress-via-keap1-kelch-like-epichlorohydrin-associated-protein-1-nrf2-nuclear-factor-e2-related-factor-2-phb2-prohibitin-2-pathway-after-subarachnoid-hemorrhage-in-rats
#5
Tongyu Zhang, Pei Wu, Enkhjargal Budbazar, Qiquan Zhu, Chengmei Sun, Jun Mo, Jianhua Peng, Vadim Gospodarev, Jiping Tang, Huaizhang Shi, John H Zhang
Background and Purpose- Mitoquinone has been reported as a mitochondria-targeting antioxidant to promote mitophagy in various chronic diseases. Here, our aim was to study the role of mitoquinone in mitophagy activation and oxidative stress-induced neuronal death reduction after subarachnoid hemorrhage (SAH) in rats. Methods- Endovascular perforation was used for SAH model of male Sprague-Dawley rats. Exogenous mitoquinone was injected intraperitoneally 1 hour after SAH. ML385, an inhibitor of Nrf2 (nuclear factor-E2-related factor 2), was given intracerebroventricularly 24 hours before SAH...
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890111/letter-by-byblow-and-stinear-regarding-article-taking-proportional-out-of-stroke-recovery
#6
LETTER
Winston D Byblow, Cathy M Stinear
No abstract text is available yet for this article.
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890110/response-by-hawe-et-al-to-letter-regarding-article-taking-proportional-out-of-stroke-recovery
#7
LETTER
Rachel L Hawe, Stephen H Scott, Sean P Dukelow
No abstract text is available yet for this article.
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890109/infratentorial-intracerebral-hemorrhage
#8
Ruiqi Chen, Xia Wang, Craig S Anderson, Thompson Robinson, Pablo M Lavados, Richard I Lindley, John Chalmers, Candice Delcourt
Background and Purpose- Infratentorial intracerebral hemorrhage (ICH) has a poor outcome but is rarely analyzed by cerebellar versus brain stem location. We evaluated this relationship and clinical outcomes among participants of the INTERACT 1 and 2 (Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials). Methods- Participants with brain stem and cerebellar ICH were compared. Logistic regression models were used to compare outcomes of death or major disability and quality of life. Results- Of 195 included patients, 92 (47%) and 103 (53%) had brain stem and cerebellar ICH, respectively...
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890108/response-by-desai-and-jadhav-to-letter-regarding-article-high-variability-in-neuronal-loss
#9
LETTER
Shashvat M Desai, Ashutosh P Jadhav
No abstract text is available yet for this article.
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30890107/health-services-research
#10
Brystana G Kaufman, Anna Kucharska-Newton, Janet Prvu Bettger
No abstract text is available yet for this article.
March 20, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30885079/emphysema-a-potential-risk-factor-for-subarachnoid-hemorrhage-and-ruptured-aortic-aneurysm
#11
Ali Mahta, Alexander E Merkler, Michael E Reznik, Jaclyn E Burch, Shadi Yaghi, Frank W Sellke, Karen L Furie, Hooman Kamel
Background and Purpose- Protease/antiprotease imbalance is implicated in the pathogenesis of emphysema and may also lead to vessel wall weakening, aneurysm development, and rupture. However, it is unclear whether emphysema is associated with cerebral and aortic aneurysm rupture. Methods- We performed a retrospective cohort study using outpatient and inpatient claims data from 2008 to 2014 from a nationally representative sample of Medicare beneficiaries ≥66 years of age. Our predictor variable was emphysema, and our outcome was hospitalization for either aneurysmal subarachnoid hemorrhage or a ruptured aortic aneurysm...
March 19, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879440/obesity-paradox-in-intracerebral-hemorrhage
#12
Steven R Persaud, Adam C Lieber, Elie Donath, Jeanette A Stingone, Neha S Dangayach, Xiangnan Zhang, J Mocco, Christopher P Kellner
Background and Purpose- Although obesity is an established risk factor for cardiovascular disease and stroke, studies have shown evidence of an obesity paradox-a protective effect of obesity in patients who already have these disease states. Data on the obesity paradox in intracerebral hemorrhage is limited. Methods- Clinical data for adult intracerebral hemorrhage patients were extracted from the National Inpatient Sample between 2007 and 2014. Multivariable logistic regression analyzed the association of body habitus with in-hospital mortality, discharge disposition, length of stay, tracheostomy or gastrostomy placement, and ventriculoperitoneal shunt placement...
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879439/spotty-calcium-on-cervicocerebral-computed-tomography-angiography-associates-with-increased-risk-of-ischemic-stroke
#13
Fan Zhang, Li Yang, Lu Gan, Zhaoyang Fan, Bill Zhou, Zixin Deng, Damini Dey, Daniel S Berman, Debiao Li, Yibin Xie
Background and Purpose- Cervicocerebral vascular calcification on computed tomography angiography is a known sign of advanced atherosclerosis. However, the clinical significance of calcification pattern remains unclear. In this study, we aimed to investigate the potential association between spotty calcium and acute ischemic stroke. Methods- This study included patients with first-time nonlacunar ischemic stroke (N=50) confirmed by brain magnetic resonance imaging or nonenhanced head computed tomography, as well as control subjects with asymptomatic carotid atherosclerosis (N=50) confirmed by carotid ultrasonography...
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879438/letter-by-shoar-et-al-regarding-article-has-outcome-of-subarachnoid-hemorrhage-changed-with-improvements-in-neurosurgical-services-study-of-2000-patients-over-2-decades-from-india
#14
LETTER
Saeed Shoar, Nasrin Shoar, Djamchid Lotfi
No abstract text is available yet for this article.
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879437/association-of-atrial-fibrillation-with-white-matter-disease
#15
Iris Yuefan Shao, Melinda C Power, Thomas Mosley, Clifford Jack, Rebecca F Gottesman, Lin Y Chen, Faye L Norby, Elsayed Z Soliman, Alvaro Alonso
Background and Purpose- Evidence suggests that atrial fibrillation (AF) is associated with increased risk of cognitive decline and dementia, even in the absence of stroke. White matter disease (WMD) is a potential mechanism linking AF to cognitive impairment. In this study, we explored the association between prevalent AF and WMD. Methods We performed a cross-sectional analysis of participants attending the ARIC-NCS (Atherosclerosis Risk in Communities-Neurocognitive Study) in 2011 to 2013 who underwent brain magnetic resonance imaging...
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879436/reduced-intracerebral-hemorrhage-and-perihematomal-edema-volumes-in-diabetics-on-sulfonylureas
#16
Hannah Irvine, Shailesh Male, Jetter Robertson, Caitlin Bell, Oladi Bentho, Christopher Streib
Background and Purpose- Sulfonylurea medications have been linked to reduced brain edema and improved outcome following ischemic stroke, but their effects on primary intracerebral hemorrhage (pICH) have not been thoroughly explored. Increasing ICH volume and perihematomal edema (PHE) volume are predictors of poor outcome in pICH. We investigated whether preexisting sulfonylurea use influenced ICH volume, PHE volume, and discharge disposition in patients with type 2 diabetes mellitus presenting with pICH. Methods- We performed a retrospective chart review of all diabetic patients presenting with pICH to 2 tertiary academic centers from 2006 to 2016...
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879435/response-by-o-donnell-and-wyers-to-letter-regarding-article-the-weekend-effect-in-carotid-endarterectomy
#17
LETTER
Thomas F X O'Donnell, Mark C Wyers
No abstract text is available yet for this article.
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879434/letter-by-galyfos-et-al-regarding-article-weekend-effect-in-carotid-endarterectomy
#18
LETTER
George Galyfos, Fragiska Sigala, Konstantinos Filis
No abstract text is available yet for this article.
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879433/response-by-singh-and-dhandapani-to-letter-regarding-article-has-outcome-of-subarachnoid-hemorrhage-changed-with-improvements-in-neurosurgical-services-study-of-2000-patients-over-2-decades-from-india
#19
LETTER
Apinderpreet Singh, Sivashanmugam Dhandapani
No abstract text is available yet for this article.
March 18, 2019: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/30879432/differential-impact-of-risk-factors-on-stroke-occurrence-among-men-versus-women-in-west-africa
#20
Albert Akpalu, Mulugeta Gebregziabher, Bruce Ovbiagele, Fred Sarfo, Henry Iheonye, Rufus Akinyemi, Onoja Akpa, Hemant K Tiwari, Donna Arnett, Kolawole Wahab, Daniel Lackland, Adeoye Abiodun, Godwin Ogbole, Carolyn Jenkins, Oyedunni Arulogun, Josephine Akpalu, Reginald Obiako, Paul Olowoyo, Michael Fawale, Morenikeji Komolafe, Godwin Osaigbovo, Yahaya Obiabo, Innocent Chukwuonye, Lukman Owolabi, Philip Adebayo, Taofiki Sunmonu, Mayowa Owolabi
Background and Purpose- The interplay between sex and the dominant risk factors for stroke occurrence in sub-Saharan Africa has not been clearly delineated. We compared the effect sizes of risk factors of stroke by sex among West Africans. Methods- SIREN study (Stroke Investigative Research and Educational Networks) is a case-control study conducted at 15 sites in Ghana and Nigeria. Cases were adults aged >18 years with computerized tomography/magnetic resonance imaging confirmed stroke, and controls were age- and sex-matched stroke-free adults...
March 18, 2019: Stroke; a Journal of Cerebral Circulation
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