Juliana Almeida Oliveira, Karine Eskandar, Júnea Chagas, Livia Leni de Oliveira do Nascimento, Daniel Dias Ribeiro, Ana Luiza Lunardi Rocha, Flávia Ribeiro de Oliveira
PURPOSE: Inherited bleeding disorders may cause heavy menstrual bleeding in women, impacting quality of life and impairing daily and social activities. The levonorgestrel-releasing intrauterine system is a potential treatment for these women, which might reduce menstrual blood loss. METHODS: We performed a systematic review and single-arm meta-analysis to examine the levonorgestrel-releasing intrauterine system in women with inherited bleeding disorders and heavy menstrual bleeding...
April 11, 2024: Contraception
Sofía Filippa, Ruvani T Jayaweera, Kelly Blanchard, Daniel Grossman
BACKGROUND: Miscarriage is a common experience; yet individuals often have negative experiences when receiving miscarriage care, signaling a gap in the quality of miscarriage care. We explore the literature on individuals' experiences with miscarriage care across a variety of dimensions and assess how these experiences align with practice recommendations. METHODS: We conducted a scoping review of peer-reviewed studies in PubMed published in English through April 30, 2022, and focused on individuals' experiences with miscarriage care in healthcare settings and on practice recommendations for providing care in a variety of countries...
April 6, 2024: Contraception
Grace A Masters, Clevanne Julce, Smita Carroll, Sharina D Person, Jeroan Allison, Nancy Byatt, Tiffany A Moore Simas
OBJECTIVES: Depression is common during pregnancy and the year following childbirth (the perinatal period). This study assessed the association of depressive symptoms and contraception decisions in perinatal individuals. STUDY DESIGN: We conducted a secondary analysis using data from the PRogram in Support of Moms (PRISM) study, a cluster randomized controlled trial of active interventions which aimed to address perinatal depression. This analysis included 191 individuals aged 18-45 who screened positive for depression on the Edinburgh Postnatal Depression Scale (EPDS, score ≥10) during pregnancy or up to 3-months postpartum...
April 5, 2024: Contraception
E Lazaris, J N Sanders, G Carter, J Olsen, A Gero, L M Gawron
OBJECTIVES: We examined differences in contraceptive uptake and discontinuation between gender-expansive individuals and cis-women in the HER Salt Lake Contraceptive Initiative. STUDY DESIGN: We used self-reported survey data to assess associations between gender identity, contraceptive uptake, and discontinuation. RESULTS: Of participants (n=4,289), 178/4289(4%) identified as gender-expansive with 157/178(88%) reporting recent sexual activity with men...
April 5, 2024: Contraception
Rachel K Jones
OBJECTIVE: The Guttmacher Institute estimated that, in 2014, 24% of US women of reproductive age would have an abortion by age 45 if the 2014 abortion rate was maintained. This study updates the estimated lifetime incidence of abortion in the year(s) just prior to the Dobbs decision, which removed federal protections for abortion. STUDY DESIGN: We used data from the Guttmacher Institute's 2021-2022 Abortion Patient Survey (APS) and population data for 2020 and 2021 from the Census Bureau, as well as abortion counts from the Guttmacher Institute's 2020 Abortion Provider Census, to estimate abortion rates, first abortion rates and cumulative abortion rates, all by age group...
April 2, 2024: Contraception
Madison Lands, Rachel L Dyer, Jane W Seymour
No abstract text is available yet for this article.
March 29, 2024: Contraception
Brian T Nguyen
OBJECTIVE: To estimate the potential market for novel male contraceptives (NMCs) using United States National Survey of Family Growth (NSFG) data, 2015-2017. METHODS: We described the market for NMCs via secondary analysis of the 2015-2017 NSFG's weighted male respondent data, utilizing surrogate markers for contraceptive switching (NSFG) and contraceptive discontinuation data from the Contraceptive CHOICE project. Potential NMC users included men relying on: [1] no methods or less effective methods but who reported that they would be "very upset" if they got someone pregnant, [2] permanent methods but who reported that they might still want more children, [3] a female partner's method that she might discontinue in the next year, [4] a male method even when his partner uses her own contraceptive...
March 28, 2024: Contraception
Alexandra E Monaco, Carolyn L Westhoff
OBJECTIVE(S): To describe patient-reported quality of care for virtual contraceptive counseling, using the 4-item Person-Centered Contraception Counseling (PCCC) scale. Secondary analyses evaluated PCCC scores by patient subgroups. STUDY DESIGN: From December 2021 to May 2022, we offered an anonymous web-based survey, to English and Spanish-speaking female patients 18 to 45 years old who had virtual visits through two Family Planning offices affiliated with Columbia University/New York Presbyterian Hospital in New York City...
March 27, 2024: Contraception
Cara Clure, Jeanelle Sheeder, Aaron Lazorwitz
OBJECTIVES: To assess the pharmacokinetics and pharmacodynamics of the etonogestrel (ENG) contraceptive implant when inserted at an alternative scapular site. STUDY DESIGN: We conducted a pilot study of healthy, reproductive-age females who underwent subdermal insertion of an ENG implant over the inferior edge of the non-dominant scapula (scapular insertion). We measured serum ENG levels over one year at nine time points. Participants completed questionnaires on insertion site and bleeding side effects...
March 27, 2024: Contraception
Tanja Boehnke, Anja Bauerfeind, Lisa Eggebrecht, Camille Cellier, Jens A Lange, Klaas Heinemann, Tessa Madden
OBJECTIVE: To compare the incidence of expulsion for different copper intrauterine device (IUD) shapes. STUDY DESIGN: We conducted a secondary analysis of the ongoing, prospective, non-interventional European Active Surveillance Study on LCS12 (EURAS-LCS12). Users of newly inserted IUDs were recruited in 10 European countries via a network of approximately 1,200 clinicians. We restricted the analysis to copper IUD users. In the main analysis, we classified copper IUDs by shape [Nova-T frame, Tatum-T frame, Multiload frame, frameless IUDs and intrauterine balls], without differentiation of size...
March 27, 2024: Contraception
Yahui Wang, Qianying Chen, Zhengnan Liu, Yun Chen, Yingling Zheng, Jialu Guo, Fan Zhou, Nengyuan Lv, Jianying Zhao, Siyi Shen, Qiaolei Yuan, Jinyi Tong
OBJECTIVE: The majority of intrauterine devices (IUDs) inserted in China are tailless, requiring intrauterine manipulations for removal and causing pain. This study aimed to investigate the analgesic efficacy of lidocaine injection into a novel disposable injectable cervical dilator for IUD removal procedures. STUDY DESIGN: A double-blinded, placebo-controlled, randomized clinical trial was conducted with women aged 18-65 years old requesting outpatient IUD removal...
March 27, 2024: Contraception
Andrea Stewart, Lisa Romero, Katherine Kortsmit, Stacey Hurst, Rachel Powell, Eva Lathrop, Maura K Whiteman, Lauren B Zapata
OBJECTIVE: To describe unmet desire for long-acting reversible contraception (LARC) after the Zika Contraception Access Network (Z-CAN) in Puerto Rico during the 2016-2017 Zika outbreak. STUDY DESIGN: Z-CAN patients completed web-based surveys about contraception experiences over a three-year period. RESULTS: Of 1,809 survey respondents, 3% never used LARC, but reported wanting it since their initial visit. As reasons for not getting LARC, nearly 50% indicated a provider-related reason and 25% reported cost...
March 27, 2024: Contraception
Christine Mauck, Andrea Thurman, Jeffrey T Jensen, Courtney A Schreiber, Jeff Baker, Melody Y Hou, Steven Chavoustie, Clint Dart, Hongsheng Wu, Jacques Ravel, Pawel Gajer, Betsy C Herold, Terry Jacot, Nadene Zack, Jessica Hatheway, Dave Friend
OBJECTIVE: Evaluate safety of Ovaprene, an investigational non-hormonal vaginal contraceptive designed for monthly use. STUDY DESIGN: Open-label, multicenter study enrolling heterosexually-active women with previous permanent contraception who underwent assessments during five menstrual cycles: baseline postcoital test cycle, diaphragm postcoital test cycle, Ovaprene safety cycle, and two Ovaprene postcoital test cycles. Safety outcomes included treatment emergent adverse events (TEAEs), systemic laboratory findings, pelvic examinations, colposcopies, Nugent scores, determination of community state types of vaginal microbiota, and anti-Escherichia coli activity and inflammatory markers in cervicovaginal fluids...
March 27, 2024: Contraception
Abigail Humphreys, Amanda Jean Stevenson, Sara Yeatman
OBJECTIVE: To describe the changes in contraceptive method use and mix among Colorado Title X clients following the 2009 Colorado Family Planning Initiative (CFPI), which allowed Colorado Title X providers to offer all contraceptive methods without medically unnecessary barriers. STUDY DESIGN: Using data on all visits to Colorado Title X clinics between 2007 and 2016 for women aged 10-49 years, we described trends in contraceptive method use by age group and race/ethnicity prior to and following the implementation of CFPI...
March 21, 2024: Contraception
Kelsey A Petrie, Erin E McCoy, Lyndsey S Benson
OBJECTIVE: Intrauterine device (IUD) users often encounter barriers to desired removal. Self-removal, while previously found to be successful only 19% of the time, may mitigate these obstacles. Our primary objective was to evaluate the effectiveness of our previously developed IUD self-removal guide. Our secondary objectives were to evaluate acceptability of the guide and characterize the self-removal process. METHODS: This was a randomized controlled trial comparing IUD self-removal success rates with and without a guide...
March 20, 2024: Contraception
Blake Zwerling, Caitlin Hendricks, Mary Peeler, Bruce Feldstein, Anne E Burke, Carolyn B Sufrin
OBJECTIVES: Healthcare chaplains are faith providers with theological education, pastoral experience, and clinical training who provide spiritual care to patients, their families, and medical staff. This study sought to characterize chaplains' experiences providing spiritual care for patients experiencing abortion and pregnancy loss, and to explore how chaplains gain competency and comfort in providing pastoral care for this patient population. STUDY DESIGN: Researchers conducted in-depth, semi-structured, qualitative interviews with currently-practicing chaplains recruited via convenience sampling in the Washington DC, Maryland, and Virginia region...
March 18, 2024: Contraception
Ushma D Upadhyay, Chris E Adkins
OBJECTIVE: In November 2022, the anti-abortion advocacy group, Alliance for Hippocratic Medicine filed a lawsuit against the U.S. Food and Drug Administration challenging the initial 2000 approval of mifepristone and its subsequent approvals, which removed unnecessary restrictions on its use, by disputing the medication's safety record. Such challenges relied on a study examining the incidence of emergency room (ER) visits following medication abortion with mifepristone and procedural abortion using Medicaid claims data from 1999-2015...
March 15, 2024: Contraception
Jennifer Yarger, Kristine Hopkins, Sarah Elmes, Irene Rossetto, Danielle Van Liefde, Stephanie De La Melena, Cynthia C Harper
OBJECTIVE: The objective of this study was to describe use of telemedicine for contraception in a sample of young adults and examine differences by health insurance coverage. STUDY DESIGN: We analyzed survey data collected May 2020-July 2022 from individuals at risk of pregnancy aged 18-29 recruited at 29 community colleges in California and Texas. We used multivariable mixed-effects logistic regression models with random effects for site and individual to compare use of telemedicine to obtain contraception by insurance status, sociodemographic characteristics, and state...
March 9, 2024: Contraception
Brandon Wagner, Kelly Cleland
OBJECTIVE: To understand patterns in demand for emergency contraception (EC), we characterize the sales of over-the-counter (OTC) levonorgestrel (LNG) EC in the United States from traditional retail outlets. STUDY DESIGN: We describe sales of OTC LNG EC using retail sales data aggregated from traditional retail channels, including grocery stores, drug stores, mass merchandisers, club stores, dollar stores, and military outlets. RESULTS: Sales of OTC LNG EC doubled between 2016 and 2022 (approximately 7...
March 8, 2024: Contraception
Caryn Dutton, Sheila K Mody, Siripanth Nippita, Laura E Dodge, Trudy Pang, Page B Pennell, Anne Davis
OBJECTIVES: To measure plasma concentrations of medroxyprogesterone acetate (MPA) in users with epilepsy treated with anti-seizure medications and compare these to MPA concentrations in those without epilepsy. METHODS: For this multi-site cross-sectional study, we obtained a single blood sample from those with epilepsy treated with various anti-seizure medications (n=18) within the week before their next depot medroxyprogesterone (DMPA) injection. Among the participants without epilepsy (n=20), 10 similarly were scheduled within the week prior to the next injection, and 10 were scheduled at earlier intervals to attempt to balance the time intervals between groups...
March 5, 2024: Contraception
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