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American Journal of Cardiology

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https://read.qxmd.com/read/30782416/gender-disparities-in-management-and-outcomes-following-transcatheter-aortic-valve-implantation-with-newer-generation-transcatheter-valves
#1
Ting-Yu Wang, Ely Gracia, Susan Callahan, Thomas Bilfinger, Henry Tannous, Robert Pyo, Smadar Kort, Hal Skopicki, Jonathan Weinstein, Neal Patel, Daniel Montellese, Giridhar Korlipara, Shamim Khan, Joanna Chikwe, Puja B Parikh
The impact of gender on management and early outcomes after transcatheter aortic valve implantation (TAVI) in the setting of newer generation transcatheter heart valves (THVs) is not well known. We evaluated gender-specific differences on clinical management and in-hospital outcomes in adults who underwent TAVI with newer generation THVs. The study population included 298 consecutive patients who underwent TAVI and received a newer generation THV (Sapien 3 [Edwards Lifesciences, Irvine, California] or Corevalve Evolut R or Evolut Pro [Medtronic, Minneapolis, Minnesota]) from December 2015 to June 2018 at an academic tertiary medical center...
February 10, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30777323/the-added-value-of-exercise-stress-echocardiography-in-patients-with-heart-failure
#2
Iacopo Fabiani, Nicola Riccardo Pugliese, Gian Giacomo Galeotti, Andreina D'Agostino, Matteo Mazzola, Roberto Pedrinelli, Frank L Dini
Doppler echocardiography can provide reliable and repeatable measures of cardiac index (CI), whereas lung ultrasound (LUS) represents a quantitative approach to assess pulmonary congestion. We tested the hypothesis that simultaneous assessment of CI and LUS during exercise stress echocardiography (ESE) may define heart failure (HF) outpatients with different risk of adverse outcome. Standard transthoracic echocardiography and LUS (B-lines) evaluation were assessed during semisupine ESE. CI and B-lines were measured at baseline and peak exercise...
February 10, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30777320/thoracoscopic-left-atrial-appendage-occlusion-for-stroke-prevention-compared-with-long-term-warfarin-therapy-in-patients-with-nonvalvular-atrial-fibrillation
#3
LETTER
Sophie Weiwei Gao, Emilie Prudence Belley-Côté, Kevin John Um, Richard Paul Whitlock
No abstract text is available yet for this article.
February 10, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30771859/sex-differences-in-risk-factors-for-incident-atrial-fibrillation-from-the-reasons-for-geographic-and-racial-differences-in-stroke-regards-study
#4
Abhishek Bose, Wesley T O'Neal, Chengyi Wu, Leslie A McClure, Suzanne E Judd, Virginia J Howard, George Howard, Elsayed Z Soliman
We examined whether the sex differences in atrial fibrillation (AF) is related to difference in risk factors leading to AF or due to a differential impact of the same risk factors in 11,806 participants (55.2 % women) from the REGARDS study. Incident AF was ascertained by electrocardiograms and medical history at a follow-up examination. Backwards elimination logistic regression was used to identify AF risk factors in men and women, separately. Over a median follow-up of 9.0 years, 588 (11.1%) men and 428 (6...
February 10, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30777322/cardiovascular-outcomes-of-patients-with-pulmonary-hypertension-undergoing-noncardiac-surgery
#5
Nathaniel R Smilowitz, Andrew Armanious, Sripal Bangalore, Harish Ramakrishna, Jeffrey S Berger
Pulmonary hypertension (PH), defined by a mean pulmonary artery pressure of >25mm Hg at rest, is strongly associated with morbidity and mortality in the perioperative period. The prevalence and outcomes of PH among patients referred for major noncardiac surgery in the United States are unknown. Patients ≥18 years of age hospitalized for noncardiac surgery were identified from Healthcare Cost and Utilization Project's National Inpatient Sample data from 2004 to 2014. Pulmonary hypertension was defined by International Classification of Diseases, Ninth Revision diagnosis codes...
February 8, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30777321/in-hospital-outcomes-of-transcatheter-aortic-valve-implantation-in-patients-with-mitral-valve-stenosis
#6
Yasser Al-Khadra, M Chadi Alraies, Fahed Darmoch, Homam Moussa Pacha, Mohamad Soud, Marvin Kajy, Amir Kaki, Wael A AlJaroudi, Chun Shing Kwok, Mamas Mamas, Samir Kapadia
Little is known about the outcome of patients with mitral stenosis (MS) who underwent transcatheter aortic valve implantation (TAVI). Therefore, we sought to evaluate the potential impact of MS on the outcome of patients who underwent TAVI using the US national cohort. Using weighted data from the National Inpatient Sample database between 2011 and 2015, we identified patients who had undergone a TAVI as a primary procedure. Patients with MS diagnosis were compared with those without MS. Univariate and multivariate logistic regression analyses were performed for the outcomes of in-hospital mortality and postprocedural complications...
February 8, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30777318/comparison-of-the-transarterial-and-transthoracic-approaches-in-nontransfemoral-transcatheter-aortic-valve-implantation
#7
Mathurin Beve, Vincent Auffret, Reda Belhaj Soulami, Jacques Tomasi, Amedeo Anselmi, Antoine Roisne, Dominique Boulmier, Marc Bedossa, Guillaume Leurent, Erwan Donal, Hervé Le Breton, Jean-Philippe Verhoye
Transfemoral approach stands as the reference access-route for transcatheter aortic valve implantation (TAVI). Nonetheless, alternatives approaches are still needed in a significant proportion of patients. This study aimed at comparing outcomes between transthoracic-approach (transapical or transaortic) and transarterial-approach (transcarotid or subclavian) TAVI. Data from 191 consecutive patients who underwent surgical-approach TAVI from May 2009 to September 2017 were analyzed. Patients were allocated in 2 groups according to the approach...
February 8, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30773248/electrocardiograms-recorded-after-asystolic-cardiac-arrest
#8
Solomon A Seifu, Pramilla N Subramaniam, David Luke Glancy
A man with a history of drug abuse was found down at home and was asystolic. Following restoration of sinus rhythm, a hypothermia protocol brought his temperature to 32.5°C (90.5°F), and large Osborn waves appeared on his electrocardiogram. With rewarming the electrocardiographic signs of hypothermia diminished. Due to hypoxic brain injury during the arrest, the patient remained unresponsive and died on the fourth hospital day.
February 8, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30773249/cardiovascular-events-and-hospital-deaths-among-patients-with-severe-sepsis
#9
Nirav Patel, Navkaranbir S Bajaj, Rajkumar Doshi, Ankur Gupta, Rajat Kalra, Amitoj Singh, Lorenzo Berra, Garima Arora, Sumanth D Prabhu, Pankaj Arora
The burden of cardiovascular events among patients hospitalized with severe sepsis and the association of these events with in-hospital mortality is not well known. We examined the incidence of cardiovascular events and their association with in-hospital mortality among patients with severe sepsis. Patients with severe sepsis from the New York State Inpatient Database from 2012 through 2014 were identified using a validated International Classification of Diseases 9th Revision, Clinical Modification code 995...
February 7, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30773247/mechanisms-of-st-elevation-myocardial-infarction-in-patients-hospitalized-for-noncardiac-conditions
#10
Khola Tahir, Eric Pauley, Xuming Dai, Sidney C Smith, Craig Sweeney, George A Stouffer
ST elevation myocardial infarction (STEMI) occurring in patients hospitalized for a noncardiac condition is associated with a high mortality rate and thus we sought to determine the mechanisms underlying STEMI in this patient population. This is a single center retrospective study of 70 patients who had STEMI while hospitalized on a noncardiac service and underwent coronary angiography. Thrombotic in-hospital STEMI was defined by angiographic or intravascular imaging evidence of intracoronary thrombus, plaque rupture, or stent thrombosis...
February 7, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30771861/relationship-between-optimism-and-outcomes-in-patients-with-chronic-angina-pectoris
#11
Alexander C Fanaroff, Kristi Prather, Amanda Brucker, Daniel Wojdyla, Linda Davidson-Ray, Daniel B Mark, Redford B Williams, John Barefoot, Giora Weisz, Ori Ben-Yehuda, Gregg W Stone, Erik Magnus Ohman, Karen P Alexander
Greater optimism regarding recovery from chronic illness is associated with improved quality of life and clinical outcomes. We performed a post-hoc analysis on the association between optimism and outcomes in Ranolazine in Patients with Incomplete Revascularization after Percutaneous Coronary Intervention (RIVER-PCI), a randomized trial in patients with chronic angina pectoris who had incomplete revascularization following percutaneous coronary intervention. At baseline, patients answered how much they agreed with the phrase, "I am optimistic about my future and returning to a normal lifestyle...
February 7, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30771860/angiographic-and-midterm-thrombosis-of-bioresorbable-vascular-scaffold-for-coronary-bifurcation-narrowings
#12
LETTER
Nicholas G Kounis, Ioanna Koniari, Grigorios Trigkas, Panagiotis Plotas, George Soufras, Periklis Davlouros, George Hahalis
No abstract text is available yet for this article.
February 7, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30771858/prevalence-of-diabetes-mellitus-in-patients-with-takotsubo-syndrome-according-to-age-and-sex
#13
LETTER
John E Madias
No abstract text is available yet for this article.
February 7, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30770090/effect-of-perioperative-antiplatelet-therapy-on-outcomes-in-patients-with-drug-eluting-stents-undergoing-elective-noncardiac-surgery
#14
Sung-Jin Hong, Min-Ji Kim, Jung-Sun Kim, Eun Hwa Kim, Jinae Lee, Chul-Min Ahn, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
We investigated the association of perioperative antiplatelet therapy (APT) and outcomes in patients with drug-eluting stent (DES) placement for noncardiac surgery (NCS). In consecutive 23,358 patients who underwent percutaneous coronary interventions between 2005 and 2016, total of 2,179 patients that required 2,179 elective NCS after DES placement were retrospectively analyzed. A net adverse clinical event (NACE), composite of death, myocardial infarction, stent thrombosis, and major bleeding, was assessed at 30 days...
February 7, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30745020/occurrence-of-atrial-fibrillation-during-dobutamine-stress-echocardiography
#15
Nicolas Mansencal, Hazrije Mustafic, Marie Hauguel-Moreau, Simon Lannou, Catherine Szymanski, Olivier Dubourg
Dobutamine stress echocardiography (DSE) is a widely used examination for assessment of coronary ischemia, but several complications have been reported. The aim of this study was to assess the incidence of atrial fibrillation (AF) during DSE, and a systematic review and meta-analysis were also performed to determine an accurate estimate of the AF incidence. Over a 16-year period, we reviewed all patients referred for DSE. We systematically analyzed all ECG performed during DSE to detect AF during the examination...
January 31, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30739658/feasibility-of-cardiac-magnetic-resonance-wideband-protocol-in-patients-with-implantable-cardioverter-defibrillators-and-its-utility-for-defining-scar
#16
Amita Singh, Keigo Kawaji, Neha Goyal, Noreen T Nazir, Andrew Beaser, Virginia O'Keefe-Baker, Karima Addetia, Roderick Tung, Peng Hu, Victor Mor-Avi, Amit R Patel
Implantable cardioverter defibrillators (ICDs) have been a relative contraindication to cardiovascular magnetic resonance imaging. Although cardiovascular magnetic resonance provides valuable information regarding scar in patients with ventricular arrhythmias or cardiomyopathy, ICDs in these patients frequently cause artifacts hindering accurate interpretation of both cine and late gadolinium enhancement (LGE) images. We sought to quantify the frequency and severity of artifact on LGE images and assess whether a modified wideband LGE protocol could improve the diagnostic yield of scar identification in agreement with invasive electroanatomic mapping (EAM)...
January 31, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30777319/outcomes-among-patients-transferred-for-revascularization-with-impella-for-acute-myocardial-infarction-with-cardiogenic-shock-from-the-cvad-registry
#17
Brian P O'Neill, Mauricio G Cohen, Mir Babar Basir, Theodore Schreiber, Navin K Kapur, Simon Dixon, Akshay K Khandelwal, Cindy Grines, Erik Magnus Ohman, William W O'Neill
The outcomes for patients transferred with cardiogenic shock and later treated with revascularization and Impella support have not previously been studied. To evaluate these outcomes, patients in cardiogenic shock were recruited from the catheter-based ventricular assist device registry, a prospective registry enrolling patients who underwent percutaneous coronary intervention with hemodynamic support using Impella 2.5 or CP. Analysis was performed on subgroups of patients who were characterized as those directly admitted to a tertiary care hospital (direct), or those transferred from an outside hospital (transfer)...
January 25, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30765065/targeted-cancer-therapies-with-pericardial-effusions-requiring-pericardiocentesis-focusing-on-immune-checkpoint-inhibitors
#18
Nicolas Palaskas, Jacob Morgan, Tina Daigle, Jose Banchs, Jean-Bernard Durand, David Hong, Aung Naing, Hung Le, Saamir A Hassan, Kaveh Karimzad, Elie Mouhayar, Peter Kim, Juan Lopez-Mattei, Kara Thompson, Syed Wamique Yusuf, Cezar Iliescu
Case reports have reported immune checkpoint inhibitors (ICI), especially nivolumab, are associated with recurrent pericardial effusions. Our objective was to determine how often patients being treated with ICI develop hemodynamically significant pericardial effusion requiring pericardiocentesis compared with other cancer therapeutics and whether the survival of patients who underwent pericardiocentesis differs according to ICI use versus standard cancer therapeutics. Our institutional review board approved catheterization laboratory data collection for all pericardiocenteses performed and all patients receiving ICI from January 1, 2015 to December 31, 2017...
January 25, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30745019/impact-of-valve-replacement-on-long-term-survival-in-asymptomatic-patients-with-severe-aortic-stenosis
#19
Ho Jin Kim, Joon Bum Kim, Hong Rae Kim, Min Ho Ju, Do-Yoon Kang, Seung-Ah Lee, Sahmin Lee, Jung-Min Ahn, Dae-Hee Kim, Sung-Ho Jung, Duk-Woo Park, Jong-Min Song, Suk Jung Choo, Cheol Hyun Chung, Jae-Kwan Song, Jae Won Lee, Seung-Jung Park
Aortic valve (AV) replacement (AVR) is the only effective treatment for severe aortic stenosis (AS). However, survival benefits by performing AVR in asymptomatic AS patients with preserved left ventricular (LV) function remains controversial. This study included 468 patients (aged 64.2 ± 13.0 years, 232 women) with preserved LV function (≥50%) and severe AS (AV area ≤1.0 cm2 , peak trans-AV velocity [Vmax ] ≥4.0 m/s, or mean AV pressure gradient ≥40 mm Hg) between 2000 and 2015. AVR was performed in 221 (47...
January 25, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30739657/patient-phenotypes-cardiovascular-risk-and-ezetimibe-treatment-in-patients-after-acute-coronary-syndromes-from-improve-it
#20
Abhinav Sharma, Jie-Lena Sun, Yuliya Lokhnygina, Matthew T Roe, Tariq Ahmad, Nihar R Desai, Michael A Blazing
Risk prediction following acute coronary syndrome (ACS) remains challenging. Data-driven machine-learning algorithms can potentially identify patients at high risk of clinical events. The Improved Reduction of Outcomes: Vytorin Efficacy International Trial randomized 18,144 post-ACS patients to ezetimibe + simvastatin or placebo + simvastatin. We performed hierarchical cluster analysis to identify patients at high risk of adverse events. Associations between clusters and outcomes were assessed using Cox proportional hazards models...
January 25, 2019: American Journal of Cardiology
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