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Equine Veterinary Journal

W M Berkowski, W F Craft, R D Whitley, D E Brooks, C E Plummer
BACKGROUND: Ulcerative keratitis with peripheral furrow formation is a poorly-described condition which has been associated with a grave prognosis due to rapid necrosis of the cornea. OBJECTIVE: To describe the infectious aetiologies associated with furrow-forming ulcerative keratitis, its overall clinical course, and the efficacy of medical and surgical intervention in horses. STUDY DESIGN: Retrospective clinical case series. METHODS: Medical records of 72 horses which presented with furrow-forming ulcerative keratitis at the University of Florida between 1987 and 2015 were reviewed...
March 18, 2019: Equine Veterinary Journal
H Wang, K J Liu, Y H Sun, L Y Cui, X Meng, G M Jiang, F W Zhao, J J Li
BACKGROUND: Salmonella enterica subspecies enterica serovar abortus equi (S. abortus equi) is well known as the aetiological agent of equine abortion. However, abortion caused by S. abortus equi has not been previously described in donkeys. OBJECTIVES: To investigate whether S. abortus equi was correlated with an abortion outbreak consisting of 61 abortions. STUDY DESIGN: Investigation of the clinical cases using pathoanatomical, bacteriological, serological and molecular approaches...
March 13, 2019: Equine Veterinary Journal
M A Frigerio, D Gómez Cisneros, I Santiago Llorente, G Manso-Díaz, J López-Sanromán
BACKGROUND: Chemical restraint is often used to perform diagnostic and minor surgical procedures; α2 -adrenoceptor agonists are the most commonly used drugs, however, the combination with an opiate can induce a profound sedation. There is a lack of kinematic studies examining the effects of the combination of these drugs on locomotor patterns. OBJECTIVES: To evaluate the duration of the effects of sedation with detomidine and detomidine combined with a low dose of butorphanol on the movement patterns of horses...
March 13, 2019: Equine Veterinary Journal
A Reynolds, J A Keen, T Fordham, R A Morgan
BACKGROUND: Obesity is a common feature of equine metabolic syndrome (EMS). In other species obese adipose tissue shows pathological features such as adipocyte hypertrophy, fibrosis, inflammation and impaired insulin signalling all of which contribute to whole body insulin dysregulation. Such adipose tissue dysfunction has not been investigated in horses. OBJECTIVES: To determine if obese horses with EMS have adipose tissue dysfunction characterised by adipocyte hypertrophy, fibrosis, inflammation and altered insulin signalling...
March 13, 2019: Equine Veterinary Journal
H C McKenzie, R A Funk, L Trager, S R Werre, M Crisman
BACKGROUND: Potomac Horse Fever (PHF) is a potentially fatal enterocolitis of horses caused by Neorickettsia risticii. The disease was originally recognised almost 40 years ago in the state of Maryland in the US. It is now known to occur in many areas of North America, as well as having been described in South America and Europe. Monocomponent PHF vaccines are available, but clinical protection with vaccination has been reported to be inconsistent. OBJECTIVES: This study was designed to assess the immunogenicity of a commercially available Potomac Horse Fever (PHF) vaccine when administered as either a monovalent PHF vaccine simultaneously co-administered with a separate monovalent Rabies vaccine or as a multivalent PHF/Rabies vaccine in horses...
March 11, 2019: Equine Veterinary Journal
D Bardell, P I Milner, K Goljanek-Whysall, M J Peffers
BACKGROUND: Strangulating small intestinal disease (SSID) carries a poor prognosis for survival in comparison to other types of colic, particularly if resection is required. Identification of markers which aid early diagnosis may prevent the need for resection, assist with more accurate prognostication, and/or support the decision on whether surgical intervention is likely to be successful, would be of significant welfare benefit. OBJECTIVES: To apply an unbiased methodology to investigate the plasma and peritoneal fluid proteomes in horses diagnosed with SSID requiring resection, to identify novel biomarkers which may be of diagnostic or prognostic value...
March 10, 2019: Equine Veterinary Journal
E L Hoaglund, K T Selberg, K A Seabaugh, A Hess, L Bass
BACKGROUND: Centrodistal joint injection is an important component of lameness evaluation and treatment. Successful injection is poor for the medial approach. The dorsolateral approach is an alternative but has not been validated with contrast medium. Radiograph-guidance has not been studied to determine its necessity or benefit for either approach. OBJECTIVES: To determine if the dorsolateral approach to the centrodistal joint is more successful than the medial approach...
March 10, 2019: Equine Veterinary Journal
J-P Lavoie, M Bullone, N Rodrigues, P Germim, B Albrecht, M von Salis-Soglio
BACKGROUND: Inhaled corticosteroids are effective for the treatment of equine asthma but they induce cortisol suppression with potential side effects. OBJECTIVES: To study the efficacy of ciclesonide, an inhaled corticosteroid with an improved safety profile, on lung function, clinical signs related to airway obstruction and serum cortisol levels in asthmatic horses exposed to a mouldy hay challenge. STUDY DESIGN: Cross-over placebo controlled, blinded, randomised experiment...
March 10, 2019: Equine Veterinary Journal
S Mainguy-Seers, A Bessonnat, K Picotte, J-P Lavoie
BACKGROUND: Inhaled corticosteroids are effective in the treatment of equine asthma. A recent study reported that nebulisation of injectable dexamethasone had low systemic bioavailability in healthy horses and could represent a cost-effective therapy for equine inflammatory lung diseases. OBJECTIVES: To determine the effects of dexamethasone nebulisation on lung function in severe asthmatic horses. It was hypothesised that dexamethasone administered by nebulisation would be more effective than the same dose administered orally...
March 8, 2019: Equine Veterinary Journal
J D Ramsay, R Evanoff, R H Mealey, E L Simpson
BACKGROUND: In racehorses, serum gamma-glutamyltransferase (GGT) activity is positively correlated with cumulative days in training and, when ≥100 IU/L, has been associated with poor performance. The prevalence of increased GGT activity in North American Thoroughbreds and its aetiopathogenesis are unknown. Four emerging viruses, pegivirus E (PgV E; equine pegivirus), hepacivirus A (HcV A; equine hepacivirus), pegivirus D (PgV D; Theiler's disease virus), and equine parvovirus-hepatitis (EqPV-H) have been identified in horses with clinical and subclinical hepatopathy...
March 8, 2019: Equine Veterinary Journal
C Tessier, J-P Pitaud, C Thorin, G Touzot-Jourde
BACKGROUND: There are no data investigating the effect of systemic morphine on the size of the stomach or the food consumption in horses. OBJECTIVES: To evaluate gastrointestinal side effects of morphine administered systemically in healthy horses by the means of clinical and ultrasonographic evaluations. STUDY DESIGN: In vivo experiment. METHODS: On day 1 of the experiment, six healthy French Trotter mares were evaluated clinically and an abdominal ultrasonography was performed 3 times 4 hours apart to record the size of the stomach, the number of contractions per minute of the duodenum, jejunum, caecum, left and right ventral colons...
March 5, 2019: Equine Veterinary Journal
S Y Broeckx, A M Martens, A L Bertone, L Van Brantegem, L Duchateau, L Van Hecke, M Dumoulin, M Oosterlinck, K Chiers, H Hussein, F Pille, J H Spaas
BACKGROUND: There is a need to improve therapies for osteoarthritis in horses. OBJECTIVES: To assess the efficacy of equine allogeneic chondrogenic-induced mesenchymal stem cells combined with equine allogeneic plasma as a novel therapy for osteoarthritis in horses. STUDY DESIGN: Randomised, double-blinded, placebo-controlled experiment. METHODS: In 12 healthy horses, osteoarthritis was induced in the metacarpophalangeal joint using an osteochondral fragment-groove model...
February 27, 2019: Equine Veterinary Journal
A L Ziegler, C A Fogle, M Burke, A T Blikslager
No abstract text is available yet for this article.
February 27, 2019: Equine Veterinary Journal
G Varley, I M Bowen, J L Habershon-Butcher, V Nicholls, G D Hallowell
BACKGROUND: Previous studies have demonstrated a poor response to healing of gastric glandular lesions with oral omeprazole and other medications. OBJECTIVES: To evaluate the efficacy of two novel treatments (misoprostol [M] and combined omeprazole-sucralfate [OS]) in the horse for gastric glandular disease. STUDY DESIGN: Prospective, clinical study. METHODS: Sixty-three sports horses with grade >1/4 glandular disease were identified by gastroscopy...
February 26, 2019: Equine Veterinary Journal
E A Walmsley, M Jackson, L Wells-Smith, R C Whitton
BACKGROUND: Subchondral bone injury at the palmar/plantar aspect of the condyles of the third metacarpal/metatarsal bone (MC/MT3) commonly causes lameness and poor performance in racehorses. Injury occurs due to repetitive loading, the magnitude of which may be influenced by the position of the distal phalanx relative to the ground surface, i.e. the solar angle. The association of solar angle and injury at the palmar/plantar condyles of distal MC/MT3 therefore warrants investigation. OBJECTIVES: Investigate the relationship between solar angle and radiopharmaceutical uptake at the palmar/plantar aspect of distal MC/MT3 on scintigraphic images of racehorses...
February 22, 2019: Equine Veterinary Journal
H Tapio, M R Raekallio, A Mykkänen, S Männikkö, M Scheinin, R C Bennett, O Vainio
BACKGROUND: Medetomidine suppresses cardiovascular function and reduces gastrointestinal motility in horses mainly through peripheral α2 -adrenoceptors. Vatinoxan, a peripheral α2 -antagonist, has been shown experimentally to alleviate the adverse effects of some α2 -agonists in horses. However, vatinoxan has not been investigated during constant-rate infusion (CRI) of medetomidine in standing horses. OBJECTIVES: To evaluate effects of vatinoxan on cardiovascular function, gastrointestinal motility, and on sedation level during CRI of medetomidine...
February 22, 2019: Equine Veterinary Journal
K Jackson, E Kelty, C Staszyk, M Tennant
BACKGROUND: Peripheral caries may cause significant oral pain and pathology and is very prevalent within the Western Australia horse population. Associations with periodontal disease have been indicated; however, further work is needed to assess the anatomical and histological aspects of the conditions, to better understand the pathophysiology. OBJECTIVES: To assess the anatomical and histopathological changes associated with equine cheek teeth peripheral caries and disease of the periodontium to better understand the pathogenesis and any association between the conditions...
February 11, 2019: Equine Veterinary Journal
S Ekman, A Lindahl, U Rüetschi, A Jansson, K Björkman, K Abrahamsson-Aurell, S Björnsdóttir, M Löfgren, L Mattsson Hultén, E Skiöldebrand
BACKGROUND: Molecular serum markers that can identify early reversible osteoarthritis (OA) in horses are lacking. OBJECTIVES: We studied serum concentrations of a novel cartilage oligomeric matrix protein (COMP) neo-epitope in horses subjected to short-term exercise and with acute lameness. The effects of circadian rhythm and age were also evaluated. STUDY DESIGN: Longitudinal studies in healthy horses and cross-sectional comparison of lame and non-lame horses...
February 10, 2019: Equine Veterinary Journal
S Egan, P Brama, D McGrath
BACKGROUND: Since Muybridge's 'horse in motion', researchers in the equine movement analysis field continue to improve objective analysis and performance monitoring while ensuring representative data capture. However, subjective evaluation remains the primary method of equine gait analysis in the applied setting, despite evidence highlighting the unreliability of this approach. OBJECTIVES: To map research trends, limitations and opportunities across the diverse equine gait analysis literature...
January 19, 2019: Equine Veterinary Journal
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