A Barry Astroff, Sylvia E Ray, Leanna M Rowe, Kim G Hilbish, Alisha L Linville, John P Stutz, William J Breslin
BACKGROUND: An integral component of developmental toxicity studies is the evaluation of fetal anatomy, which consists of external, visceral, and skeletal examinations. The visceral examination includes an assessment of the fetal head which, in the rat, is typically completed after chemical fixation. Because chemical fixation requires approximately 7 days, a comprehensive visceral examination, including the head, of the fetal rodent cannot be completed at the time of cesarean section...
August 2002: Teratology