journal
https://read.qxmd.com/read/36948167/characteristics-of-gastric-stasis-due-to-deformation-after-endoscopic-submucosal-dissection-in-the-lower-part-of-the-stomach
#1
JOURNAL ARTICLE
Hiroshi Takayama, Takashi Toyonaga, Tetsuya Yoshizaki, Hirofumi Abe, Tatsuya Nakai, Chise Ueda, Satoshi Urakami, Hidetoshi Kaku, Yusaku Shimamoto, Kei Matsumoto, Kazunori Tsuda, Hiroya Sakaguchi, Shinichi Baba, Hiroshi Takihara, Nobuaki Ikezawa, Shinwa Tanaka, Madoka Takao, Toshitatsu Takao, Yoshinori Morita, Yuzo Kodama
INTRODUCTION: Gastric stasis due to deformation occurs after endoscopic submucosal dissection in the lower part of the stomach. Endoscopic balloon dilation can improve gastric stasis due to stenosis; however, endoscopic balloon dilation cannot improve gastric stasis due to deformation. Furthermore, the characteristics of gastric stasis due to deformation are unknown. This study aimed to evaluate the characteristics of gastric stasis due to deformation after endoscopic submucosal dissection in the lower part of the stomach, focusing on the differences between stenosis and deformation...
March 22, 2023: Digestion
https://read.qxmd.com/read/36907172/risk-factors-for-ceftriaxone-associated-pseudolithiasis-in-adults
#2
JOURNAL ARTICLE
Akihiro Matsumi, Takeshi Tomoda, Hiroyuki Terasawa, Yuki Fujii, Tatsuhiro Yamazaki, Daisuke Uchida, Kazuyuki Matsumoto, Shigeru Horiguchi, Koichiro Tsutsumi, Hironari Kato
INTRODUCTION: Ceftriaxone (CTRX) is known to occasionally cause pseudolithiasis. This condition is often observed in children; however, few studies have reported the incidence and risk factors for CTRX-associated pseudolithiasis. METHODS: In this single-center retrospective study, we investigated the incidence of and risk factors for CTRX-associated pseudolithiasis in adults. All patients underwent computed tomography to confirm pseudolithiasis before and after CTRX administration...
March 10, 2023: Digestion
https://read.qxmd.com/read/36893744/clinical-features-focusing-on-extraintestinal-manifestations-in-japanese-patients-with-inflammatory-bowel-diseases-far-east-1000
#3
Yuki Ohta, Takashi Taida, Jun Kato, Sadahisa Ogasawara, Yuhei Oyama, Yukiyo Mamiya, Hayato Nakazawa, Ryosuke Horio, Chihiro Goto, Satsuki Takahashi, Akane Kurosugi, Michiko Sonoda, Wataru Shiratori, Tatsuya Kaneko, Yuya Yokoyama, Naoki Akizue, Hideaki Ishigami, Hirotaka Koseki, Kenichiro Okimoto, Keiko Saito, Masaya Saito, Tomoaki Matsumura, Tomoo Nakagawa, Yoshio Masuya, Yoshihiro Fukuda, Yoshio Kitsukawa, Haruhisa Shimura, Toshio Tsuyuguchi, Naoya Kato
BACKGROUND: Patients with inflammatory bowel diseases (IBD) can develop extraintestinal manifestations (EIMs) during the disease course, which sometimes impact their quality of life. OBJECTIVES: This study aimed to clarify the prevalence and types of EIMs using a hospital-based IBD cohort in Japan. METHODS: A patient cohort with IBD was established in 2019, as participated by 15 hospitals in Chiba Prefecture of Japan. Using this cohort, the prevalence and types of EIMs, which are defined based on previous reports and the Japanese guidelines, were investigated...
March 9, 2023: Digestion
https://read.qxmd.com/read/36889285/secondary-sclerosing-cholangitis-due-to-severe-covid-19-an-emerging-disease-entity
#4
JOURNAL ARTICLE
Michael Seifert, Guntje Kneiseler, Alexander Dechene
INTRODUCTION: Coronavirus disease 2019 (COVID-19) can lead to many extrapulmonary manifestations. In this case series, we report on 7 patients developing secondary sclerosing cholangitis (SSC) after severe COVID-19 with intensive care treatment. METHODS: Between March 2020 and November 2021, 544 patient cases with cholangitis treated at a German tertiary care centre were screened for SSC. Patients found to be suffering from SSC were assigned to COVID-19 group if SSC presented after a severe course of COVID-19 and to non-COVID-19 group if not...
March 8, 2023: Digestion
https://read.qxmd.com/read/36750039/saliva-secretion-is-significantly-lower-in-female-patients-with-mild-reflux-esophagitis-than-in-female-healthy-controls
#5
JOURNAL ARTICLE
Eri Momma, Mai Koeda, Yoshimasa Hoshikawa, Tomohide Tanabe, Shintaro Hoshino, Yuichi Kitasako, Noriyuki Kawami, Katsuhiko Iwakiri
INTRODUCTION: Saliva secretion is significantly lower in patients with mild reflux esophagitis than in healthy controls. A previous study on healthy controls showed that stimulated saliva secretion was lower in females than in males. Saliva secretion may be lower in female patients with mild reflux esophagitis than in male patients. Therefore, the present study investigated sex differences in saliva secretion in patients with mild reflux esophagitis. METHODS: Twenty-five male patients with mild reflux esophagitis, 25 male healthy controls, 24 female patients with mild reflux esophagitis, and 24 female healthy controls were recruited for this case-control study...
February 7, 2023: Digestion
https://read.qxmd.com/read/36746122/impact-of-transarterial-chemoembolization-or-hepatic-artery-infusion-chemotherapy-on-liver-function-after-hepatocellular-carcinoma-resection-an-observational-study
#6
JOURNAL ARTICLE
Rongbin Yue, Xiqiang Liu
INTRODUCTION: Liver surgery leads to a high degree of heterogeneity in the prognosis of hepatocellular carcinoma (HCC) patients. However, most previous studies focused on the postoperative therapeutic effects of other treatments, with relatively few studies on the impacts on liver function. This study investigated the impact of transarterial chemoembolization (TACE) and hepatic artery infusion chemotherapy (HAIC) on liver function after HCC resection from various angles. METHODS: 138 HCC patients were enrolled, including 27 patients who received TACE and 80 patients who received HAIC...
February 6, 2023: Digestion
https://read.qxmd.com/read/36716726/long-term-clinical-course-after-successful-initial-treatment-in-patients-with-mild-erosive-esophagitis-a-prospective-follow-up-study
#7
JOURNAL ARTICLE
Hideharu Okanobu, Tomohiko Kohno, Kazuki Boda, Hidenori Ochi, Yoshinari Furukawa
INTRODUCTION: This study aimed to investigate the clinical course of patients with healed mild erosive esophagitis and clarify the predictive factors for continuous treatment. METHOD: Fifty-one patients with mild erosive esophagitis who confirmed mucosal healing by endoscopy after initial treatment with vonoprazan (VPZ) were enrolled. The patients continued subsequent treatment of their choice: maintenance therapy with VPZ 10 mg (n = 15), on-demand therapy with VPZ 20 mg (n = 19), or no medication (n = 17)...
January 30, 2023: Digestion
https://read.qxmd.com/read/36649681/a-multicenter-prospective-validation-study-on-selective-endoscopic-resection-of-sessile-serrated-lesions-using-magnifying-colonoscopy-in-clinical-practice
#8
JOURNAL ARTICLE
Daizen Hirata, Hiroshi Kashida, Tsuguhiro Matsumoto, Chikara Ebisutani, Akira Teramoto, Mineo Iwatate, Santa Hattori, Mikio Fujita, Wataru Sano, Yoriaki Komeda, Yasushi Sano, Yoshitaka Murakami, Masatoshi Kudo
INTRODUCTION: Sessile serrated lesions (SSLs) have malignant potential for colorectal cancer in the serrated pathway. Selective endoscopic resection of SSLs would reduce medical costs and procedure-related accidents, but the accurate endoscopic differentiation of SSLs from hyperplastic polyps (HPs) is challenging. To explore the differential diagnostic performance of magnifying colonoscopy in distinguishing SSLs from HPs, we conducted a multicenter prospective validation study in clinical practice...
January 17, 2023: Digestion
https://read.qxmd.com/read/36649678/examination-on-factors-affecting-symptom-change-after-drug-withdrawal-in-patients-with-mild-erosive-gastroesophageal-reflux-disease-undergoing-symptom-controlled-maintenance-therapy-with-acid-secretion-inhibition-drugs
#9
JOURNAL ARTICLE
Hironori Tanaka, Toshihisa Takeuchi, Shinya Nishida, Hitosi Hongo, Michiaki Takii, Takeshi Higashino, Makoto Sanomura, Hirota Miyazaki, Masahiro Hoshimoto, Tsuguhiro Kimura, Masahiro Sakaguchi, Takashi Abe, Akitoshi Hakoda, Noriaki Sugawara, Taro Iwatsubo, Shinpei Kawaguchi, Kazuhiro Ota, Yuichi Kojima, Kazuhide Higuchi
INTRODUCTION: In patients with gastroesophageal reflux disease (GERD) on maintenance therapy with acid-suppressive drugs, it is not clear what background factors allow patients to discontinue the drugs. The aims of this study were to examine the relationship of the changes in the frequency and severity of gastrointestinal symptoms after discontinuation of acid-secretion inhibitors for erosive GERD (eGERD) with possible patient background factors and to identify factors that influence these changes...
January 17, 2023: Digestion
https://read.qxmd.com/read/36646064/the-single-nucleotide-polymorphisms-rs4143370-and-rs34904192-in-mir155hg-were-associated-with-esophageal-cancer-risk-in-the-chinese-han-population
#10
JOURNAL ARTICLE
Zhuoqi Jia, Weiru Zhou, Jing Liang, Guangjian Zhang, Junke Fu, Xuejun Sun
INTRODUCTION: MIR155HG has been found to play an important role in malignant tumors, but little research has been done on its association with esophageal cancer (ESCC). The aim of this study was to investigate the relationship between MIR155HG polymorphisms and ESCC susceptibility in the Chinese Han population. METHODS: 511 ESCC patients and 487 healthy controls were selected for this study. All subjects were genotyped using the Agena MassARRAY platform. We assessed the association between seven single nucleotide polymorphisms (SNPs) of the MIR155HG and ESCC risk by genetic model analysis...
January 16, 2023: Digestion
https://read.qxmd.com/read/36646047/analysis-of-circulating-dna-to-assess-prognoses-for-metastatic-colorectal-cancer-patients-treated-with-regorafenib-dose-escalation-therapy-a-retrospective-exploratory-analysis-of-the-recc-trial
#11
JOURNAL ARTICLE
Ryo Ohta, Takeshi Yamada, Masato Nakamura, Masanobu Enomoto, Makoto Takahashi, Hajime Yokomizo, Chihiro Kosugi, Kei Ishimaru, Hiromichi Sonoda, Hidekazu Kuramochi, Yoichiro Yoshida, Shinji Furuya, Keiji Hirata, Hiroshi Yoshida, Keijiro Nozawa, Yojiro Hashiguchi, Hideyuki Ishida, Keiji Koda, Kenji Katsumata, Kazuhiro Sakamoto
INTRODUCTION: Regorafenib is a multi-kinase inhibitor approved for patients with metastatic colorectal cancer (mCRC) who were previously treated with standard therapies. A few reports showed the impact of KRAS mutation on therapeutic efficacy of regorafenib. Only one study reported poor prognoses for patients treated with regorafenib who had large amounts of circulating cell-free DNA (cfDNA). In the present study, we evaluated the impact of KRAS mutations in tissue or plasma and amounts of cfDNA on prognoses of mCRC patients treated with regorafenib...
January 16, 2023: Digestion
https://read.qxmd.com/read/36630931/endoscopic-ligation-with-o-ring-closure-for-mucosal-defects-after-rectal-endoscopic-submucosal-dissection-a-feasibility-study-with-video
#12
JOURNAL ARTICLE
Naoya Tada, Hideki Kobara, Noriko Nishiyama, Kazuhiro Kozuka, Takanori Matsui, Taiga Chiyo, Nobuya Kobayashi, Tatsuo Yachida, Shintaro Fujihara, Tsutomu Masaki
INTRODUCTION: Mucosal defect closure after colorectal endoscopic submucosal dissection (ESD) may prevent post-ESD adverse events. Delayed bleeding is a particular concern in the rectum due to the presence of numerous blood vessels. However, rectal defect closure often fails due to the thick rectal wall. This study aimed to examine the feasibility of our newly developed endoscopic ligation with O-ring closure (E-LOC) for defects after rectal ESD. METHODS: This was a prospective observational study conducted at a single institution...
January 11, 2023: Digestion
https://read.qxmd.com/read/36617409/comparison-of-efficacy-and-safety-between-endoscopic-retrograde-cholangiopancreatography-and-percutaneous-transhepatic-cholangial-drainage-for-the-treatment-of-malignant-obstructive-jaundice-a-systematic-review-and-meta-analysis
#13
Liwei Pang, Shuodong Wu, Jing Kong
BACKGROUND: At present, endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic cholangial drainage (PTCD) are frequently used for reducing malignant obstructive jaundice (MOJ). However, it is controversial as to which method is superior in terms of efficacy and safety. OBJECTIVES: The aim of this study was to compare the safety, feasibility, and clinical benefits of ERCP and PTCD in matched cases of MOJ. METHODS: The Web of Science, Cochrane, PubMed, and CNKI databases were searched systematically to identify studies published between January 2000 and December 2019, without language restrictions, that compared ERCP and PTCD in patients with MOJ...
January 6, 2023: Digestion
https://read.qxmd.com/read/36603570/relapse-and-need-for-extended-immunosuppression-novel-features-of-drug-induced-autoimmune-hepatitis
#14
Sabine Weber, Alexander L Gerbes
BACKGROUND: Drug-induced autoimmune hepatitis (DI-AIH) has been proposed as a distinct phenotype of drug-induced liver injury (DILI), and frequently has been associated with specific drugs, such as minocycline and nitrofurantoin. However, no clear definition of DI-AIH has been established thus far. OBJECTIVES: We aimed to identify features distinguishing DI-AIH from DILI and idiopathic autoimmune hepatitis (AIH) in an attempt to further define a DI-AIH phenotype...
January 5, 2023: Digestion
https://read.qxmd.com/read/36603569/diagnostic-performance-of-endocytoscopy-for-esophageal-eosinophilia
#15
JOURNAL ARTICLE
Emiko Hida, Koichi Muroi, Naomi Kakushima, Satoshi Furune, Eri Ishikawa, Yasuyuki Mizutani, Tsunaki Sawada, Maeda Keiko, Takeshi Yamamura, Takuya Ishikawa, Kazuhiro Furukawa, Eizaburo Ohno, Masanao Nakamura, Kazuki Nishida, Mitsuhiro Fujishiro, Hiroki Kawashima
INTRODUCTION: Eosinophils in the esophageal epithelium are unevenly distributed in eosinophilic esophagitis (EoE). Esophageal eosinophilia (EE) may be observable by endocytoscopy (EC). This study aimed to evaluate the diagnostic performance of EC for the diagnosis of EE. METHODS: A total of 33 EoE patients underwent EC with methylene blue staining from March 2020 to April 2021. A total of 194 EC images with corresponding biopsies were obtained. Three findings of EC, increased squamous cells (item I), increased inflammatory cells (item II), and cells with bilobed nuclei (item III), were established...
January 5, 2023: Digestion
https://read.qxmd.com/read/36599306/clinical-evaluation-of-computer-aided-colorectal-neoplasia-detection-using-a-novel-endoscopic-artificial-intelligence-a-single-center-randomized-controlled-trial
#16
JOURNAL ARTICLE
Hirotaka Nakashima, Naoko Kitazawa, Chika Fukuyama, Hiroshi Kawachi, Hiroshi Kawahira, Kumiko Momma, Nobuhiro Sakaki
INTRODUCTION: Computer-aided diagnostic systems are emerging in the field of gastrointestinal endoscopy. In this study, we assessed the clinical performance of the computer-aided detection (CADe) of colonic adenomas using a new endoscopic artificial intelligence system. METHODS: This was a single-center prospective randomized study including 415 participants allocated into the CADe group (n = 207) and control group (n = 208). All endoscopic examinations were performed by experienced endoscopists...
January 4, 2023: Digestion
https://read.qxmd.com/read/36596283/author-index-vol-104-no-1-2023
#17
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
2023: Digestion
https://read.qxmd.com/read/36580899/proton-pump-inhibitor-treatment-has-little-effects-on-secretion-of-saliva-in-patients-with-proton-pump-inhibitor-responsive-mild-reflux-esophagitis-and-non-erosive-reflux-disease
#18
JOURNAL ARTICLE
Yoshimasa Hoshikawa, Eri Momma, Shintaro Hoshino, Noriyuki Kawami, Yuichi Kitasako, Masaomi Ikeda, Katsuhiko Iwakiri
INTRODUCTION: The secretion of saliva, which is triggered by acid reflux into the esophagus via the esophagosalivary reflex, plays a crucial role in the defensive mechanisms of the esophagus. The volume of saliva secreted in patients with gastroesophageal reflux disease (GERD) is reduced. However, the effects of proton pump inhibitors (PPI) on the secretion of saliva have rarely been reported. Therefore, the present study investigated changes in the volume and pH of saliva after the cessation of PPI...
December 29, 2022: Digestion
https://read.qxmd.com/read/36577392/identification-of-biomarkers-associated-with-the-prognoses-of-colorectal-cancer-patients
#19
JOURNAL ARTICLE
Yuejun Fang, Xiaoan Zhan
INTRODUCTION: Colorectal cancer (CRC) is a common cancer. As metastasis and recurrence are main causes of CRC death, it is of great significance to find prognostic biomarkers. METHODS: Data related to CRC were collected from GEO database. The patients were grouped based on clinical information, and the differentially expressed genes (DEGs) were obtained by differential analysis. GO and KEGG pathway enrichment analyses were conducted based on DEGs. Cox combined with LASSO regression analysis was applied to screen out the key genes that used to build the prognostic model...
December 28, 2022: Digestion
https://read.qxmd.com/read/36502791/association-between-mucosal-healing-and-lipid-profiles-in-patients-with-ulcerative-colitis-a-cross-sectional-study
#20
JOURNAL ARTICLE
Sen Yagi, Shinya Furukawa, Teruki Miyake, Kana Shiraishi, Kazuhiro Tange, Yu Hashimoto, Shogo Kitahata, Tomoyuki Ninomiya, Seiyuu Suzuki, Naozumi Shibata, Hidehiro Murakami, Katsuhisa Ohashi, Hideomi Tomida, Yasunori Yamamoto, Eiji Takeshita, Yoshio Ikeda, Yoichi Hiasa
INTRODUCTION: Recent meta-analysis showed that ulcerative colitis (UC) is a risk factor for cardiovascular disease (CVD). Dyslipidemia is a well-established risk factor for CVD. However, evidence regarding inflammatory bowel disease (IBD), including UC and lipid profiles, is limited. Additionally, no study has assessed the association between endoscopic activity and lipid profiles in patients with IBD. Therefore, we aimed to clarify the association between mucosal healing (MH) and lipid profiles in patients with UC...
December 9, 2022: Digestion
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