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Indian Journal of Cancer

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https://read.qxmd.com/read/30829288/a-pituitary-tumor-turned-to-be-a-glioma-a-surgical-case-from-the-madras-general-hospital-1928
#1
LETTER
Ramya Raman, Anantanarayanan Raman
A three-page paper entitled "A case of glioma (embryonal neurocytoma) of the brain simulating pituitary tumour," written by K. G. Pandalai, Surgeon at the Madras General Hospital, and T. B. Menon, Pathologist at the Madras Medical College, was published in the Indian Medical Gazette. This paper refers to an occasional finding of a brain tumor (a glioma), presurgically diagnosed as a pituitary tumor, in 1928. This was close to the period when surgeons across the developed world believed in that cancers were by no means common among the native people of India as it was in Europe...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829287/iatrogenic-alkalosis-during-high-dose-methotrexate-therapy-an-avertable-cause
#2
LETTER
Kritika Agrawal, Satyajit Majhi, Nishkarsh Gupta, Rakesh Garg
No abstract text is available yet for this article.
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829286/health-and-well-being-of-cancer-caregivers-in-a-changed-role-of-breadwinners
#3
LETTER
Md Mahbub Hossain
No abstract text is available yet for this article.
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829285/skin-and-mucosal-ulcerations-and-acute-kidney-failure-due-to-methotrexate-toxicity-in-a-patient-with-non-hodgkin-s-lymphoma
#4
LETTER
Xia Song, Yinyin Guo, Hui Zhao, Wenbiao Hu
No abstract text is available yet for this article.
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829284/cancer-has-almost-a-similar-psychosocial-impact-on-family-caregivers-as-those-of-the-patients-but-are-we-doing-enough-for-them
#5
Sourav Goswami, Subodh Saran Gupta
No abstract text is available yet for this article.
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829283/potential-role-of-whole-body-diffusion-magnetic-resonance-imaging-in-tumor-staging-for-pregnant-patients-with-cancer
#6
Abhishek Mahajan, G V Santhosh Kumar, Tanvi Vaidya, Meenakshi Thakur, Subhash Desai
Malignancy during pregnancy poses a serious threat to the growing fetus. In this special situation, the diagnostic procedures and treatment to cancer will be more damaging to the developing fetus than the cancer itself. However, to safeguard the health of the mother from cancer, appropriate diagnostic and therapeutic tools are to be used that would minimize risk to fetal health. Diffusion-weighted whole-body imaging with background body signal suppression has the potential to answer most of these diagnostic dilemmas in the case of malignancy in pregnancy...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829282/trousseau-s-sign-in-the-left-internal-jugular-vein-in-gastric-cancer
#7
Dillibabu Ethiraj, Venkatraman Indiran, Kannan Kanakaraj, Prabakaran Madhuraimuthu
No abstract text is available yet for this article.
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829281/creatinine-kinase-elevation-and-peripheral-neuropathy-during-nivolumab-treatment-of-a-patient-with-metastatic-renal-cell-carcinoma
#8
Melih Simsek, Mehmet Bilici, Salim Basol Tekin
We report elevation of creatinine kinase (CK), which is an uncommon adverse event related to treatment with nivolumab. Nivolumab is a monoclonal antibody against programmed cell death-1 and an effective agent in metastatic renal cell carcinoma (RCCa). Here, we report a case of 58 year-old male receiving nivolumab as fourth-line treatment for metastatic RCCa. The patient was admitted to our clinic with pelvic pain and weakness in his legs. Elevated CK level was noted and he was hospitalized. About 1 mg/kg methylprednisolone was initiated and nivolumab was discontinued...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829280/a-novel-frameshift-mutation-in-the-mlh1-gene-in-a-patient-with-lynch-syndrome
#9
Arti S Pandey, Sudip Shrestha
A novel mutation in the MLH1 gene likely to be pathogenic for Lynch syndrome was discovered in a proband with a family history of colon cancer. Immunohistochemistry showed negative expression of PMS2 and MLH1 in the resected tumor sample. The mutation lies at the highly conserved C-terminus of the MLH1 protein, the region through which it dimerizes with PMS2 to carry out its mismatch repair function.
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829279/prevalence-of-oral-mucosal-lesions-among-smokeless-tobacco-usage-a-cross-sectional-study
#10
Kaveri Hallikeri, Venktesh Naikmasur, Kruthika Guttal, Mangalore Shodan, Niranjan Kochli Chennappa
BACKGROUND: Tobacco use is one of the most prevalent forms of habit and associated with development of potential malignant disorders. The aim of the present study was to investigate the prevalence and distribution of oral mucosal lesions (OMLs) among smokeless tobacco users. MATERIALS AND METHODS: This is a hospital-based cross-sectional study. All the patients with the history of smokeless tobacco habit were included in the study. The patients were interviewed using the preformed questionnaire, including the patient's demographic details, the type of habit, duration, frequency, and the associated oral mucosal pathology...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829278/nicotinic-acetylcholine-receptor-gene-polymorphism-is-not-associated-with-tobacco-related-oral-squamous-cell-carcinoma
#11
Deepa Rajesh, S M Azeem Mohiyuddin, Sharath Balakrishna, A V Moideen Kutty
BACKGROUND: Nicotinic acetylcholine receptor is implicated in carcinogenesis indirectly through increasing nicotine dependence and directly through its impact on cell-cycle regulation. Functional polymorphism in nicotinic acetylcholine receptor alpha-5 subunit gene (CHRNA5 c.1192G>A; rs16969968) is associated with nicotine dependence and risk of lung cancer. AIM: The aim of this study was to evaluate the association of CHRNA5 c.1192G>A polymorphism with the risk of oral squamous cell carcinoma (OSCC)...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829277/the-tobacco-trade-and-trail-in-karnataka
#12
Punith Shetty, Roomani Srivastav, Arpan Debnath, R Murali, A Shamala
CONTEXT: Tobacco use is a major public health challenge in India with 275 million adults consuming different tobacco products. Despite innumerable laws, the overall picture of the current system is not clear and the menace of tobacco persists. What does it take to stop this menace? The present study made an attempt to throw some light on the prevailing discrepancy in the current system. AIMS: The aim of the study was to explore the knowledge and attitude of people involved in growth and sales of tobacco...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829276/designing-and-validation-of-text-messages-for-m-health-intervention-for-tobacco-cessation-and-management
#13
Puneet Chahar, Vikrant R Mohanty, Y B Aswini
BACKGROUND: Tobacco is a growing epidemic and tobacco-related death results in health consequences and lost economic opportunities. Tobacco cessation efforts mandate the use of multiple strategies to bring about behaviour change. AIM: To develop and validate health promotive text messages using transtheoretical model and prospect theory for behaviour change. SETTINGS AND DESIGN: The present observational study was conducted in a tertiary care hospital, Delhi among patients reporting at Tobacco Cessation Centre (TCC)...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829275/effectiveness-of-two-psychological-intervention-techniques-for-de-addiction-among-patients-with-addiction-to-tobacco-and-alcohol-a-double-blind-randomized-control-trial
#14
Rahul Ganavadiya, B R Chandra Shekar, S Suma, Pallavi Singh, Ruchika Gupta, Poonam Tomar Rana, Shubham Jain
Objective: The objective of this study was to evaluate effectiveness of two psychological intervention techniques (reading - writing therapy vs. games - narrative therapy) using motivational intervention alone as a control among tobacco addicts. Materials and Method: This randomized control trial was conducted over a period of 6 months from April to September 2013 at a de-addiction center in Madhya Pradesh, India. Patients with moderate-to-high levels of dependence as determined by Fagerstrom Test for Nicotine Dependence (FTND) admitted for treatment in a de-addiction center were recruited...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829274/jordanian-physicians-perceived-barriers-and-facilitators-to-patient-participation-in-treatment-decision-making-an-exploratory-study
#15
Rana F Obeidat, Robin M Lally
BACKGROUND: Successful implementation of shared decision-making in clinical encounters is influenced by system, patient, and clinician factors that both facilitate and present barriers to patient-centered care. Little is known about which factors Jordanian physicians believe influence their ability to implement shared decision-making with cancer patients. AIMS: To determine Jordanian physicians' perceived barriers and facilitators to patient participation in treatment decision-making...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829273/the-risk-of-secondary-cancer-in-pediatric-medulloblastoma-patients-due-to-three-dimensional-conformal-radiotherapy-and-intensity-modulated-radiotherapy
#16
Reham S Sherif, Wael M Elshemey, Ehab M Attalla
BACKGROUND: Craniospinal irradiation (CSI) is the standard radiation therapy treatment for medulloblastoma. The aim of this study was to estimate and compare the lifetime risk of radiation-induced secondary cancer in pediatric medulloblastoma patients using three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT). MATERIALS AND METHODS: 3D-CRT and IMRT plans were performed for 10 CSI pediatric patients. The average absorbed doses for organs at risk (OARs) was calculated from dose-volume histograms on the treatment planning system...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829272/examination-of-methylation-changes-of-vim-cxcr4-dok7-and-spdef-genes-in-peripheral-blood-dna-in-breast-cancer-patients
#17
Atefeh Shirkavand, Zahra Niki Boroujeni, Seyed Ahmad Aleyasin
BACKGROUND: Studying whole blood DNA methylation as a risk marker has valuable applications in either diagnosis or staging of breast cancer. We investigated whole blood DNA methylation status of VIM, CXCR4, DOK7, and SPDEF genes in breast cancer patients in comparison to healthy control subjects. MATERIALS AND METHODS: 60 patients with breast cancer and 40 healthy controls were examined. Genomic DNA isolated from peripheral blood and restriction enzyme polymerase chain reaction (REP) method was applied for analysis...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829271/comparison-of-resection-margins-and-cosmetic-outcome-following-intraoperative-ultrasound-guided-excision-versus-conventional-palpation-guided-breast-conservation-surgery-in-breast-cancer-a-randomized-controlled-trial
#18
Tejas Vispute, V Seenu, Rajinder Parshad, Smriti Hari, Sanjay Thulkar, Sandeep Mathur
INTRODUCTION: Use of intraoperative ultrasound (IOUS) has been shown to help achieve satisfactory cosmesis and negative margins in breast conserving surgery (BCS). This study has been done to compare the oncological and cosmetic outcomes following BCS using conventional palpatory method and IOUS. MATERIALS AND METHODS: This is a prospective randomized controlled trial conducted at a tertiary care teaching and research institute in India. Patients with early operable breast cancer willing for BCS were included...
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829270/harmonic-scalpel-versus-conventional-diathermy-is-one-really-better-than-the-other
#19
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30829269/comparison-of-harmonic-scalpel-and-conventional-technique-in-the-surgery-for-breast-cancer-a-systematic-review-and-meta-analysis
#20
Zili Zhang, Lin Li, Yi Pang, Qi Li, Chunli Guo, Yongchao Wang, Chengpei Zhu, Xiangchao Meng
BACKGROUND: Harmonic scalpel is considered as a promising surgical tool for breast cancer, while its advantage over conventional approach is still controversial. Therefore, we performed this meta-analysis to compare the outcomes of harmonic scalpel and conventional tools in the surgery for breast cancer. MATERIALS AND METHODS: Studies reporting the outcomes of harmonic scalpel and conventional technologies were systematically searched from online databases, PubMed and EMBASE up to April 30, 2018...
October 2018: Indian Journal of Cancer
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