journal
https://read.qxmd.com/read/38614940/efficacy-and-safety-of-0-5-colchicine-cream-versus-5-5-fluorouracil-cream-in-the-treatment-of-cutaneous-field-cancerization-a-randomized-clinical-trial
#1
JOURNAL ARTICLE
Amanda Soares Teixeira, Ivanka Miranda de Castro Martins, Anna Carolina Miola, Hélio Amante Miot
BACKGROUND: 5-Fluorouracil (5-FU) is a first-line drug to treat cutaneous field cancerization (CFC). There are few clinical trials with topical colchicine (COL). OBJECTIVE: To evaluate the effectiveness of 0.5% COL cream versus 5% 5-FU cream in the treatment of CFC. METHOD: This was a randomized, open, self-controlled clinical trial. Forty-five patients (90 forearms), with three to ten actinic keratoses (AK) on each forearm, used 0.5% COL cream 2×/day for seven days on one forearm, and 5% 5-FU cream 2× /day, for 21 days, on the other forearm...
April 12, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38614939/assessment-by-the-scheimpflug-imaging-system-of-corneal-clarity-and-anterior-segment-properties-in-rosacea-patients
#2
JOURNAL ARTICLE
Erman Bozali, Duygu Yalınbaş Yeter, Mustafa Tosun, Anıl Selim Apa
OBJECTIVE: To evaluate the effects of rosacea on ocular surface changes such as alterations in dry eye parameters, corneal densitometry, and aberrations, in comparison with healthy controls. METHODS: A total of 88 eyes of 44 patients diagnosed with rosacea and 88 eyes of 44 healthy controls were enrolled in this cross-sectional study. All participants underwent a comprehensive dermatologic and ophthalmic examination and Tear Break-Up Time (TBUT) and Schirmer-1 tests were performed...
April 12, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38614938/predicting-skin-graft-failure-on-the-scalp-by-intraoperative-laser-speckle-analysis
#3
André Pinho, Ana Brinca, Carolina Figueiredo, Duarte Flor, Ricardo Vieira
No abstract text is available yet for this article.
April 12, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38614937/secondary-syphilis-occurring-under-anti-cd20-therapy-risks-progression-and-approach
#4
Luiz Augusto Fabricio de Melo Garbers, Tissiana Marques de Haes, Cacilda da Silva Souza
No abstract text is available yet for this article.
April 12, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38594178/autosomal-dominant-monilethrix-with-incomplete-penetrance-due-to-a-novel-krt86-mutation-in-a-chinese-family
#5
Ru Dai, Tingting Wang, Xianjie Wu
No abstract text is available yet for this article.
April 8, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38594177/familiar-white-sponge-nevus
#6
Camino Prada-García, Asunción González-Morán, Xenia Pérez-González
No abstract text is available yet for this article.
April 8, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38594176/pigmented-eccrine-syringofibroadenocarcinoma-simulating-malignant-melanoma
#7
Bianca Cristina Dantas, Luana Rytholz Castro, Natália Scardua Mariano Alves, Bethânia Cabral Cavalli Swiczar, Neusa Yuriko Sakai Valente
No abstract text is available yet for this article.
April 8, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38584024/paraneoplastic-acquired-ichthyosis-as-the-first-manifestation-in-breast-implant-associated-anaplastic-large-cell-lymphoma
#8
Héctor Chiang Wong, Pilar Martínez Sánchez, María Del Carmen González Guzmán
No abstract text is available yet for this article.
April 6, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38555263/presence-of-merkel-cell-polyomavirus-dna-and-large-t-antigen-in-keratinocyte-carcinomas-and-its-correlation-with-immunohistochemical-markers-p16-p53-and-ki67
#9
JOURNAL ARTICLE
T R Bellott, Flávio Barbosa Luz, Anna Karoline Fausto da Silva, Rafael Brandão Varella, Mayra Carrijo Rochael, Rafaela Elvira Rozza-de-Menezes, Luciana Pantaleão
BACKGROUND: Merkel cell polyomavirus (MCPyV), a human polyomavirus that is unequivocally linked to merkel cell carcinoma (MCC), has been found in association with keratinocytes carcinomas (KC), especially basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC). Nevertheless, there is scarce information about the possible involvement of MCPyV in the development of KC. OBJECTIVES: To assess the presence of MCPyV DNA and Large-T Antigen (LT-Ag) via Polymerase Chain Reaction (PCR) and Immunohistochemistry (IHC) in cases of KC, and to correlate its presence with immunohistochemical markers p16, p53, and ki67, tumor type and subtype, sun-exposed location, and epidemiological data...
March 29, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38553282/recalcitrant-folliculitis-decalvans-successfully-controlled-with-adalimumab
#10
José Ramos, António Magarreiro Silva, Ana Marta António, João Alves
No abstract text is available yet for this article.
March 28, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38548550/are-behavioral-interventions-a-better-choice-for-atopic-dermatitis-patients-a-meta-analysis-of-6-randomized-controlled-trials
#11
JOURNAL ARTICLE
Wenying Zhong, Wei Li, Guangsheng Wu
BACKGROUND: The treatment for atopic dermatitis (AD) has been the focus of clinical research, and behavioral intervention is considered an indispensable treatment method. To our knowledge, no relevant meta-analysis has evaluated the effects of behavioral interventions on atopic dermatitis. OBJECTIVES: To evaluate the effects of behavioral interventions on atopic dermatitis. METHODS: The authors searched PubMed, EMBASE, and Cochrane CENTRAL to retrieve relevant RCTs (up to Feb 2022)...
March 27, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38548549/expression-analysis-and-biological-regulation-of-silencing-regulatory-protein-6-sirt6-in-cutaneous-squamous-cell-carcinoma
#12
JOURNAL ARTICLE
Sai Chen, Hongxia Chen, Xu Wang, Dongmei Zhang, Li Zhang, Jiawei Cheng, Qi Zhang, Zhixiang Hua, Xu Miao, Jian Shi
BACKGROUND: Cutaneous squamous cell carcinoma (CSCC) is one of the most common types of skin cancer worldwide. Therefore, the identification of biomarkers associated with CSCC progression could aid in the early detection of high-risk squamous cell carcinoma and the development of novel therapeutic strategies. OBJECTIVE: This study aimed to investigate the expression patterns of silent mating type Information Regulation 2 homolog 6 (SIRT6) in CSCC and its clinical significance...
March 27, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38522973/a-new-proposal-for-phenotypic-classification-and-outcome-assessment-of-dermatomyositis-based-on-clinical-manifestations-and-serological-testing
#13
JOURNAL ARTICLE
Ting Huang, Ting Ding, Liqing Ding, Shasha Xie, Xiaojing Li, Qiming Meng, Xiaomeng Wu, Hui Luo, Hongjun Zhao
BACKGROUND: Dermatomyositis (DM) is an infrequent disease subgroup of idiopathic inflammatory myopathies characterized by distinct skin lesions. However, high heterogeneity makes clinical diagnosis and treatment of DM very challenging. OBJECTIVES: Unsupervised classification in DM patients and analysis of key factors related to clinical outcomes. METHODS: This retrospective study was conducted between 2017 and 2022 at the Department of Rheumatology, Xiangya Hospital, Central South University...
March 23, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38521707/tattoos-risks-and-complications-clinical-and-histopathological-approach
#14
REVIEW
David Chalarca-Cañas, Mario A Caviedes-Cleves, Luis A Correa-Londoño, Juan Pablo Ospina-Gómez, Margarita M Velásquez-Lopera
BACKGROUND: Skin modification through tattoos is as old as humanity itself. However, this trend is on the rise, and with the use of different types of pigments and application practices, both cutaneous and systemic complications can arise. Adverse reactions can be grouped into five classes: inflammatory, infectious, neoplastic, aesthetic, and miscellaneous. On histopathology, inflammatory reactions can exhibit a lichenoid pattern or present as spongiotic dermatitis, granulomatous reactions, pseudolymphoma, pseudoepitheliomatous hyperplasia, or scleroderma/morphea-like changes...
March 22, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38521706/targeted-therapy-for-immune-mediated-skin-diseases-what-should-a-dermatologist-know
#15
REVIEW
Edinson López, Raúl Cabrera, Cristóbal Lecaros
BACKGROUND: Molecularly targeted therapies, such as monoclonal antibodies (mAbs) and Janus Kinase inhibitors (JAKis), have emerged as essential tools in the treatment of dermatological diseases. These therapies modulate the immune system through specific signaling pathways, providing effective alternatives to traditional systemic immunosuppressive agents. This review aims to provide an updated summary of targeted immune therapies for inflammatory skin diseases, considering their pathophysiology, efficacy, dosage, and safety profiles...
March 22, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38521705/prevalence-of-the-association-of-vulvar-lichen-sclerosis-with-hashimoto-s-thyroiditis
#16
Marcela Scárdua Sabbagh de Azevedo, Antônio Chambo Filho, Lucia Martins Diniz, July Barcellos Quimquim, Vickie White Loureiro Souza, Luana Amaral de Moura
No abstract text is available yet for this article.
March 22, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38521704/follicular-unit-grafting-in-chronic-ulcers-a-valuable-technique-for-integrated-management
#17
JOURNAL ARTICLE
Anahi Belatti, Florencia Bertarini, Virginia Pombo, Luis Mazzuoccolo, Damian Ferrario
Chronic ulcers significantly affect the quality of life of patients and impose a high cost on the healthcare system. The therapeutic management should be comprehensive, taking into consideration the etiological diagnosis of the wound and the characteristics of the wound bed when deciding on a therapeutic proposal appropriate to the healing phase, correcting factors that delay healing. During the epithelialization phase, repair techniques with grafts are recommended to shorten re-epithelialization time, improve the quality of scar tissue, and achieve adequate pain management...
March 22, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38493053/prurigo-review-of-its-pathogenesis-diagnosis-and-treatment
#18
REVIEW
Paulo Ricardo Criado, Mayra Ianhez, Roberta Fachini Jardim Criado, Juliana Nakano, Daniel Lorenzini, Hélio Amante Miot
Prurigo is a reactive, hyperplastic skin condition characterized by pruritic papules, plaques, and/or nodules. The temporal classification includes acute/subacute and chronic disease (≥ 6 weeks), with different clinical variants, synonymies, and underlying etiological factors. The immunology of chronic prurigo shows similarities with atopic dermatitis due to the involvement of IL-4 and IL-13, IL-22, and IL-31. Treatment includes antihistamines, topical steroids, dupilumab, and JAK inhibitors. Several conditions manifest clinically as prurigo-like lesions, and the correct clinical diagnosis must precede correct treatment...
March 16, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38493052/association-of-sociodemographic-and-clinical-factors-with-the-quality-of-life-of-brazilian-individuals-with-neurofibromatosis-type-1-a-cross-sectional-study
#19
JOURNAL ARTICLE
Natália Parenti Bicudo, Carla Maria Ramos Germano, Roberta Teixeira de Moraes, Lucimar Retto da Silva de Avó, Rosalie E Ferner, Débora Gusmão Melo
BACKGROUND: Neurofibromatosis type 1 (NF1) is a rare genetic disorder with a wide range of clinical manifestations, notably neurocutaneous features, that can lead to emotional and physical consequences. OBJECTIVES: This study assessed the influence of sociodemographic factors and clinical features of the disease on the quality of life of Brazilian individuals with NF1. METHODS: This is a descriptive cross-sectional study. Data were collected from 101 individuals with NF1 using the Brazilian version of the Impact of NF1 on Quality of Life Questionnaire (INF1-QoL), a form with information on sociodemographic characteristics, and an NF1 visibility self-evaluation scale...
March 16, 2024: Anais Brasileiros de Dermatologia
https://read.qxmd.com/read/38443301/benign-cephalic-histiocytosis-exuberant-manifestation-in-an-infant
#20
Ana Flávia Teixeira de Abreu, Rebecca Perez de Amorim, Pedro Marciano de Oliveira, Marcelo Padovani de Toledo Moraes, Silvio Alencar Marques
No abstract text is available yet for this article.
March 4, 2024: Anais Brasileiros de Dermatologia
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