journal
https://read.qxmd.com/read/38757598/hyponutrition-among-newly-diagnosed-gastric-cancer
#1
JOURNAL ARTICLE
Van Tran Pham, Mai Ly Thi Nguyen, Chi Pham, Quoc Vuong LE, Doanh Hieu Tran, Thanh Son LE, Linh Toan Nguyen, Khac Cuong Bui
OBJECTIVES: This study aims to determine the malnutrition status among Vietnamese patients newly diagnosed with gastric cancer (GC). BACKGROUND: GC remains the top rank of common and deadly diseases. With limited clinical manifestation, most GC patients were diagnosed at late stages when tumor is not radically resected. Malnutrition was associated with poor prognosis of GC, such as prolonged hospitalization, limited treatment efficacy and low survival rate. METHODS: The cross-sectional descriptive study recruited 77 patients newly diagnosed with GC and 90 healthy individuals (HC)...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757597/do-neutrophil-lymphocyte-monocyte-lymphocyte-platelet-lymphocyte-ratios-affect-prognosis-and-stage-in-avascular-necrosis-of-the-femoral-head
#2
JOURNAL ARTICLE
Alp Yekta Gokalp, Sezgin Bahadir Tekin
INTRODUCTION: Avascular necrosis of the femoral head (AVNFH) is an osteonecrosis type caused by ischaemic osteocyte loss of femoral head, and its exact pathomechanism is still unknown. Neutrophil, lymphocyte, monocyte, platelet levels in complete blood count and ratios between these levels have been used by almost all medical disciplines as accesible and reliable biomarkers of immune response. Aim of this study is to identify the effects of neutrophil/lymphocyte (NL), monocyte/lymphocyte (ML), platelet/lymphocyte (PLT/L) ratios on prognosis and stage in patients with avascular necrosis of the femoral head (AVNFH)...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757596/is-increased-activator-protein-1-in-cerebrospinal-fluid-as-a-potential-biomarker-that-distinguishes-idiopathic-intracranial-hypertension-from-multiple-sclerosis
#3
JOURNAL ARTICLE
Seyda Karabork, Humeyra Celik, Ali Dogan Dursun, Handan Ankarali, Sule Aydin Turkoglu
OBJECTIVES: To distinguish whether idiopathic intracranial hypertension (IIH) is a condition predisposing to multiple sclerosis (MS) or an isolated disease, the current gene transcription factor Activator Protein-1 (AP-1) was evaluated with its potential to differentiate both diseases. BACKGROUND: The aim of this study was to investigate the use of AP-1 as biomarkers for the discrimination of IIH and MS. METHODS: AP-1, TNF-α, and IL-6 protein values in the CSF of the cases were evaluated by the ELISA method...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757595/investigation-of-sars-cov-2-antibody-levels-after-covid-19-vaccine-in-chronic-hepatitis-b%C3%A2-patients
#4
JOURNAL ARTICLE
Sami Kinikli, Fatma Elçin Afsar, Ali Dogan Dursun, Altan Aksoy, Gizem Karahan, Salih Cesur, Çigdem Ataman Hatipoglu, Gunay Tuncer Ertem, Fatma Sebnem Erdinc, Ufuk Urtimur
AIM: The aim was to compare SARS-CoV-2 IgG antibody levels in chronic hepatitis B patients and healthcare personnel selected as the control group and to determine factors such as age, gender, vaccine type, and number of vaccines that may affect the antibody levels. MATERIALS AND METHODS: 87 chronic hepatitis B (CHB) patients followed in Ankara Training and Research Hospital Infectious Diseases Clinic and Mamak State Hospital Infectious Diseases outpatient clinic and 89 healthcare personnel selected as the control group were included in the study...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757594/relationship-of-intensive-care-scoring-systems-with-neutrophil-lymphocyte-ratio-platelet-lymphocyte-ratio-and-mean-platelet-volume-values
#5
JOURNAL ARTICLE
Ali Altinbas, Bilge Olgun Keles, Elvan Tekir Yilmaz, Sema Coban
OBJECTIVE: We evaluated the relationship between NLR, PLR, and MPV values and scoring systems frequently used in intensive care units in our study. METHODS: In our retrospective study, patients aged 18 years and over who received treatment in the intensive care unit for at least 48 hours were included. Demographic data, such as age, gender, APACHE II, SOFA and GCS scores, expected mortality, and 30-day and 1-year mortality rates were recorded. RESULTS: There was a significant positive correlation between MPV values and APACHE, SOFA, and expected mortality rates, and a significant negative correlation between GCS values...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757593/evaluation-of-inflammatory-biomarkers-affecting-mortality-in-acute-cholecystitis-in-the-emergency-department
#6
JOURNAL ARTICLE
Nafis Vural, Murat Duyan, Ali Saridas, Elif Ertas
OBJECTIVES: The aim of this study was to investigate the effectiveness of pan-immune inflammation value (PIV), systemic immune-inflammatory index (SII), and systemic inflammation response index (SIRI) in predicting mortality in acute cholecystitis (AC). BACKGROUND: Abdominal pain is one of the most frequent complaints encountered by physicians at emergency department (ED). METHODS: This clinical study is a cross-sectional study among patients admitted to the emergency department of a tertiary hospital and diagnosed with AC...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757592/challenges-of-laboratory-diagnosis-of-lyme-disease-%C3%A2-questionnaire-survey-results
#7
JOURNAL ARTICLE
Vanda Repiska, Barbora Gutaiova, Simona Humplikova, Ivana Shawkatova
UNLABELLED: Lyme disease. Our second goal was to identify bacterial and viral co-infections occurring concurrently with Lyme disease. Furthermore, it was our intention to also analyze the correlation of laboratory testing with the occurrence of erythema migrans (EM). BACKGROUND: The accuracy in diagnostic testing for Lyme disease in the early stages of infection is an important factor necessary for delivering proper treatment to patients. METHODS: A total of 173 individuals with confirmed Lyme disease or with laboratory testing underway participated in the quantitative survey...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757591/chloroquine-and-cinchonine-affect-rat-vascular-smooth-muscle-tonus-through-calcium-channels-in-silico-and-in-vitro-approaches
#8
JOURNAL ARTICLE
Gorana Nedin Rankovic, Vanja Dimitrov, Marija Cvetanovic, Dane Krtinic, Dragana Stokanovic, Tamara Jovanovic, Milica Veljkovic, Jovana Cvetkovic, Goran Rankovic
BACKGROUND: In the present study, two structurally similar alkaloids from trees of Cinchona genus, chloroquine and cinchonine, were examined for their vasorelaxant effects in a model of phenylephrine-induced smooth muscle contractions. METHODS: Potential mechanisms of action associated with endothelial vasorelaxant compounds, voltage-gated Ca2+ channels (LTCCs), and inositol triphosphate receptors were examined in isolated rat aortic rings. Also, an in silico approach was used to predict the activity of the two test compounds...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757590/use-of-endoanchors-during-index-endovascular-aortic-aneurysm-repair-in-patients-with-hostile-proximal-aortic-neck-anatomy
#9
JOURNAL ARTICLE
Jozef Sivak, Martin Suchac, Maros Daxner, Katarina Kmetkova, Jan Sykora, Jana Zapletalova, Kamil Zelenak, Iveta Simkova
PURPOSE: Standard endovascular aortic aneurysm repair (EVAR) is sometimes the only treatment option for patients with hostile aortic neck anatomy, but it carries an increased risk of both early and late procedure-related complications. The aim of this study was to report on single-center experience with the Heli-FX EndoAnchors (Medtronic, Santa Rosa, CA) as an adjunctive procedure to endovascular aneurysm repair (EVAR) for prevention and perioperative treatment of proximal neck complications in patients with hostile neck anatomy...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38757589/thromboembolic-complications-following-implantation-of-durable-left-ventricular-assist-devices
#10
JOURNAL ARTICLE
Rastislav Cikrai, Frantisek Golas, Panagiotis Artemiou, Ivo Gasparovic, Stefan Durdik, Michal Hulman
INTRODUCTION: As the utilization of left-ventricular assist devices (LVADs) continues to rise and patients experience extended survival duration with these devices, the overall incidence of adverse events and complications has shown a notable increase. Among the major adverse events, thromboembolic complications are particularly significant. The aim of this study is to present our experience and assess the risk of thromboembolic complications after implantation of durable continuous-flow left-ventricular assist devices (CF-LVAD) in patients with end-stage heart failure...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624060/secondary-attack-rate-of-covid-19-in-shared-households-in-slovakia
#11
JOURNAL ARTICLE
Alexandra Brazinova, Miriam Fulova, Martina Kotrbancova, Jana Perzelova, Jaroslava Sokolova, Marek Majdan
OBJECTIVE: The objective of this study was to estimate the secondary attack rate in unvaccinated members of households of two regions in the Slovak Republic for the period November 2020 ‒ April 2021. INTRODUCTION: SARS-CoV-2 infection poses a high risk of transmission in close-contact indoor settings, such as households. The household transmissibility of SARS-CoV-2 varies widely across countries. METHODS: We included 278 households for SARS-CoV-2 transmission analysis...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624059/systemic-inflammatory-response-index-and-monocyte-to-high-density-lipoprotein-ratio-new-biomarkers-remarking-the-inflammation-in-primary-sarcopenia-the-simps-study
#12
JOURNAL ARTICLE
Bahar Bektan Kanat, Veysel Suzan, Gulru Ulugerger Avci, Damla Unal, Tugce Emiroglu Gedik, Deniz Suna Erdincler, Alper Doventas, Hakan Yavuzer
OBJECTIVE: To investigate the relationship of sarcopenia with systemic inflammation response index (SIRI), monocyte to high-density lipoprotein ratio (MHR) and platelet parameters in geriatric patients. METHODS: We designed a cross-sectional retrospective study in patients presented to a geriatric outpatient clinic for the first time. The diagnosis of sarcopenia was made in accordance with the EWGSOP2 criteria. SIRI, MHR, mean platelet volume /Platelet count (MPV/Plt), platelet distribution width /Platelet (PDW/Plt), platelet/lymphocyte ratio (PLR) were calculated from fasting blood test results at the time of admission...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624058/effectiveness-of-treatment-of-arterial-hypertension-in-central-europe-from-1972-to-2022
#13
JOURNAL ARTICLE
Arian Taniwall, Jan Broz, Michala Lustigova, Juan P Gonzalez-Rivas, Geraldo De Albuquerque Maranhao Neto, Iuliia Pavlovska, Pavlina Krollova, Barbora Berka, Ondrej Patek, Lucia Fackovcova, Petr Hoffmann, Jana Mlichova, Ludmila Brunerova, Jana Urbanova
BACKGROUND: Hypertension is a leading cause of cardiovascular disease. This review examines the literature on hypertension control in the Czech Republic from 1972 to 2022 addressing limited data on its effectiveness. METHODS: A literature review was conducted covering the period from 1972 to 2022, utilizing MEDLINE (PubMed), Web of Science, and Scopus databases. Articles were selected based on title and abstract evaluations, with full-text reviews performed as needed...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624057/serum-tryptase-levels-in-patients-with-post-acute-covid-19-syndrome
#14
JOURNAL ARTICLE
Ana Hadak, Durdica Premec, Marina Perkovic, Vanja Dolenec, Marina Bozan, Vanja Nedeljkovic, Tomislav Kelava, Ivan Markovic
OBJECTIVES: to investigate the difference in serum tryptase levels between post-acute COVID-19 syndrome (PACS) patients and controls. BACKGROUND: PACS has been defined as symptoms that persist for more than 3 months after the onset of COVID-19. The pathogenesis is still unknown, but mast cell activation has been proposed as one of the mechanisms, and increased serum tryptase levels have been demonstrated in PACS patients. METHODS: A total number of 133 patients were included: 50 with PACS, 37 asymptomatic COVID-19 convalescents, and 46 controls with a negative history of COVID-19...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624056/expression-of-bcl2-tp53-foxa1-and-gata3-in-pta-bladder-cancer-recurrence
#15
JOURNAL ARTICLE
Zuzana Varchulova Novakova, Stefan Harsanyi, Katarina Bevizova, Marcela Kuniakova, Lucia Schwarzova, Branislav Trebaticky, Lubos Danisovic, Stanislav Ziaran
OBJECTIVES: In this study, we analyzed pTa bladder cancer (BC) for molecular markers BCL2, TP53, FOXA1, and GATA3 in relation to cancer recurrence. METHODS: We analyzed samples of 79 patients with the pTa stage of BC using a real-time polymerase chain reaction (real-time PCR) between September 2018 and September 2020. The expression levels of BCL2, TP53, FOXA1, and GATA3 were compared with homologous non-tumor bladder tissue. RESULTS: Expression of FOXA1, GATA3, and TP53 was significantly higher (p<0...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624055/estimation-of-prognosis-in-patients-after-decompressive-craniectomy-after-malignant-hemispheric-infarction-multifactorial-scoring-scale
#16
JOURNAL ARTICLE
Robert Chrenko, Svorad Trnovec, Martin Hanko, Kamil Kolejak, Milan Liska, Barbora Nedomova
BACKGROUND: Patient's age is considered to be one of the most relevant factors in selecting surgical candidates for decompressive hemicraniectomy after malignant hemispheric infarction. However, questions about surgical indication in older patients, patients with consciousness disorder or patients with large infarctions remain unanswered. OBJECTIVE: Our aim was to design a multifactorial scoring scale based on a combination of patient-specific factors in order to optimize the assessment of prognosis in patients after hemicraniectomy malignant strokes...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624054/comparison-of-pco2gap-svo2-and-plasmatic-lactate-in-patients-on-venoarterial-extracorporeal-circulation-support
#17
JOURNAL ARTICLE
Branislav Bezak, Panagiotis Artemiou, Matej Ondrusek, Michal Hulman
BACKGROUND: Clinical assessment and laboratory markers provide valuable information on tissue perfusion and enhance the optimalisation of management in the treatment of patients on extracorporeal membrane oxygenation (ECMO). The PCO2 gap is a reliable marker of cardiac output (CO) and perfusion. The aim of this study was to evaluate the PCO2 gap as a marker of tissue hypoperfusion and to compare it to lactate and SvO2. METHODS: A single-center retrospective study on 131 adult cardiac patients who underwent ECMO implantation in the period between 2010 and 2021...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624053/rare-instances-of-concomitant-acute-myocardial-infarction-and-stroke
#18
REVIEW
Damian Maciejewski, Karol Nowak, Magdalena Wawak, Aleksandra Karcinska, Lukasz Tekieli, Mariusz Trystula, Robert Musial, Jakub Podolec, Piotr Pieniazek, Jaroslaw Zalewski
Cardio-cerebral infarction (CCI) is a term coined to describe concomitant myocardial infarction and acute ischemic stroke. Acute myocardial infarction and stroke, as separate events, constitute some of the most important causes for disability and mortality in aging societies. Stroke can either occur simultaneously with myocardial infarction or become a serious complication of myocardial infarction and/or its treatment. The frequency of CCI has been reported at a 0.009% incidence rate in stroke patients and is associated with an extremely high mortality...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624052/electrocardiographic-biochemical-and-scintigraphic-evidence-for-the-cardioprotective-effect-of-paricalcitol-and-vitamin-d3-on-doxorubicin-induced-acute-cardiotoxicity-in-rats
#19
JOURNAL ARTICLE
Reyhan Koroglu, Mustafa Koroglu, Hatice Aygun
AIM: We aimed to investigate the possible cardioprotective effects of paricalcitol (PR), its vitamin D receptor agonist, and vitamin D3 (VIT-D3) on an experimental model of doxorubicin (DX) cardiotoxicity by 99mTc-PYP scintigraphy, electrocardiographic (ECG) and biochemical methods. METHOD: Forty-two male Wistar/Albino rats (250‒300 g; aged 10‒12 weeks) were randomly separated into six groups, namely into control (CN), doxorubicin (DX), paricalcitol (PR), vitamin D3 (VIT-D3), paricalcitol + doxorubicin (PR+DX), and vitamin D3 + doxorubicin (VIT-D3+DX) groups...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38624051/the-diagnostic-significance-of-c4d-deposits-as-an-immunohistochemical-proof-of-complement-activation-in-kidney-glomerular-pathologies-and-kidney-transplantation
#20
REVIEW
Stanislav Hresko, Martina Madarova, Miroslava Dobosova, Nikola Palusekova, Petra Niznerova, Stanislav Ziaran, Ivan Varga
C4d, a split product of C4 activation in classical and lectin pathways of the complement system activation, has been regarded as a footprint of tissue damage in antibody-mediated rejection in transplantology. The introduction of C4d staining into daily clinical practice aroused an ever-increasing interest in the role of antibody-mediated mechanisms in kidney allograft rejection. However, this marker of complement activation is also important in other various kidney glomerular pathologies such as immunoglobulin A nephropathy, membranoproliferative glomerulonephritis, lupus nephritis, and others...
2024: Bratislavské Lekárske Listy
journal
journal
21495
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.