Journals Scandinavian Journal of Gastro...

Scandinavian Journal of Gastroenterology
Mingyan Zhang, Haijun Mou, Guangchuan Wang, Ping Li, Derun Kong, Senlin Li, Qian Feng, Ruonan Sun, Jinming Yan, Guangjun Huang, Yongjun Shi, Biguang Tuo, Chunqing Zhang
BACKGROUND AND STUDY AIMS: The optimal treatment for gastric varices (GVs) is a topic that remains definite for this study. This study compared the clinical outcomes of clip-assisted endoscopic cyanoacrylate injection (clip-ECI) to conventional endoscopic cyanoacrylate injection (con-ECI) for the treatment of GVs with a gastrorenal shunt. PATIENTS AND METHODS: Data were collected retrospectively in five medical centers from 2015 to 2020. The patients were treated with con-ECI ( n  = 126) or clip-ECI ( n  = 148)...
April 26, 2023: Scandinavian Journal of Gastroenterology
Dong Fang, Yi Han, Chenglin Zhu, Zhenwang Shi, Deming Bao, Liming Wang, Qin Xu
OBJECTIVE: To systematically evaluate the efficacy and safety of the method of placing the distal stent opening above the duodenal papilla (hereinafter referred to Above method) for endoscopic retrograde stent internal drainage in MBO patients. METHODS: PubMed, Embase, Web of science and Cochrane databases were searched to identify clinical studies comparing the stent distal opening mounted above the papilla and across the papilla (hereinafter referred to Across method), Comparison indicators included stent patency, stent occlusion rate, clinical success rate, overall complication rate, postoperative cholangitis rate, and overall survival...
April 26, 2023: Scandinavian Journal of Gastroenterology
Zhang Zhang, Xiaojia Chen, Tingting Cao, Yumei Ning, Haizhou Wang, Fan Wang, Qiu Zhao, Jun Fang
OBJECTIVE: To examine the time variation in polyp detection for colonoscopies performed in a tertiary hospital and to explore independent factors that predict polyp detection rate (PDR). METHODS: Data on all patients who underwent colonoscopy for the diagnostic purpose at our endoscopy center in Zhongnan Hospital of Wuhan University from January 2021 to December 2021 were reviewed. The start time of included colonoscopies for eligible patients was recorded. PDR and polyps detected per colonoscopy (PPC) were calculated...
April 25, 2023: Scandinavian Journal of Gastroenterology
Charlotte Lock Rud, Steven Brantlov, Josephine Reinert Quist, Trine Levring Wilkens, Jens Frederik Dahlerup, Simon Lal, Palle Bekker Jeppesen, Christian Lodberg Hvas
OBJECTIVE: Patients with an ileostomy may experience postoperative electrolyte derangement and dehydration but are presumed to stabilise thereafter. We aimed to investigate the prevalence of sodium depletion in stable outpatients with an ileostomy and applied established methods to estimate their fluid status. METHODS: We invited 178 patients with an ileostomy through a region-wide Quality-of-Life-survey to undergo outpatient evaluation of their sodium and fluid status...
April 25, 2023: Scandinavian Journal of Gastroenterology
Hartwig Maetzel, Wiktor Rutkowski, Nikola Panic, Amir Mari, Aleksandra Hedström, Paula Kulinski, Per Stål, Sven Petersson, Torkel B Brismar, J Matthias Löhr, Miroslav Vujasinovic
INTRODUCTION: The prevalence of non-alcoholic fatty pancreas disease (NAFPD) is estimated as 2-46% among patients without known pancreatic diseases. An association between NAFPD and non-alcoholic fatty liver disease (NAFLD) has been proposed, as well as an association between NAFPD and pancreatic exocrine insufficiency (PEI). PATIENTS AND METHODS: Patients with histologically confirmed NAFLD were included in the study. The control group consisted of individuals included in a surveillance screening program...
April 23, 2023: Scandinavian Journal of Gastroenterology
Ge Yu, Weiliang Jiang, Zhiyuan Cheng, Rong Wan
BACKGROUND: Organ failure (OF) largely governs the outcomes and mortality in patients with acute pancreatitis (AP), but there is a lack of optimal prognostic biomarker for OF. This study is designed to investigate whether the serum apolipoprotein A-I (Apo A-I) level can predict OF in patients with AP. METHODS: A total of 424 patients with AP were reviewed in the study, and we finally got 228 patients eligible for analysis. Patients were divided into two groups based on serum Apo A-I level...
April 19, 2023: Scandinavian Journal of Gastroenterology
Ilona Hyvärinen, Maria Hukkinen, Reetta Kivisaari, Leena Kylänpää, Arno Nordin, Heikki Mäkisalo, Mikko P Pakarinen
Nearly half of operated patients developed long-term postoperative complications. A novel association between CMs and IBD was observed. Although no hepatobiliary malignancies regardless of treatment modality were encountered, the number of patients and length of follow-up remained limited.
April 18, 2023: Scandinavian Journal of Gastroenterology
Caiguang Liu, Shukai Zhan, Na Li, Tong Tu, Jianming Lin, Manying Li, Minhu Chen, Zhirong Zeng, Xiaojun Zhuang
BACKGROUND: The indolent course of treatment-naive patients with inflammatory bowel disease (IBD) is confirmed predictable based on clinical characteristics. Current evidences supported that bile acids (BAs) alteration might be promising biomarkers in the field of IBD. We aimed to analyze the alterations of BAs as the disease progresses and explore their predictive value for indolent course of IBD. METHODS: The indolent course of IBD was defined as a disease course without need for strict interventions throughout the entire follow-up...
April 18, 2023: Scandinavian Journal of Gastroenterology
Ebba Asplund, Mattias Bergqvist, Maura Krook, J-Matthias Löhr
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) patients might benefit from a biomarker to more precisely prognosticate their overall survival to make more informed treatment and surveillance decisions. The aim of the study was to assess the circulating biomarker Thymidine kinase (TK) activity in samples from patients with PDAC to improve prognostic precision. MATERIAL AND METHODS: Using the sensitive TK activity (TKa) assay DiviTum®, serum samples from 60 PDAC patients were analyzed...
April 11, 2023: Scandinavian Journal of Gastroenterology
Gabriel Allo, Martin Bürger, Seung-Hun Chon, Dilan Gülcicegi, Laurenz Krämer, Tobias Goeser, Fabian Kütting
BACKGROUND: Upper gastrointestinal bleeding (UGIB) from malignancies is associated with a poor outcome. Only a small number of studies on gastrointestinal tumor bleeding have been published so far, focusing mainly on bleeding from gastric cancer. Since the information on patients with UGIB from esophageal cancer appears insufficient, this study aimed to present clinical and endoscopic findings, treatment options as well as clinical outcomes such as rebleeding and survival of those patients...
April 8, 2023: Scandinavian Journal of Gastroenterology
Kjetil Søreide
No abstract text is available yet for this article.
April 6, 2023: Scandinavian Journal of Gastroenterology
Chao Shi, Xuxu Liu, Zhihong Xie, Haijun Sun, Chenjun Hao, Dongbo Xue, Xianzhi Meng
OBJECTIVES: This study aimed to investigate the relationship between lifestyle and gallstones. MATERIALS AND METHODS: We performed an observational study using the 2018-2020 National Health and Nutrition Examination Survey (NHANES). Univariate and multivariate-adjusted logistic regression analyses were performed to assess the correlations between lifestyle factors and gallstone risk. Second, Mendelian randomization (MR) was applied to decrease the causal relationship between lifestyle factors and gallstones...
April 6, 2023: Scandinavian Journal of Gastroenterology
Robin Zenlander, Claudia Fredolini, Jochen M Schwenk, Ingvar Rydén, Peter Påhlsson, Christian Löwbeer, Gösta Eggertsen, Per Stål
BACKGROUND: Patients with liver cirrhosis are recommended ultrasonography screening for early detection of hepatocellular carcinoma to increase the chances of curative treatment. However, ultrasonography alone lacks in sensitivity. Adding plasma biomarkers may increase the detection rate. We performed a broad exploratory analysis to find new plasma proteins with potential applicability for HCC screening in patients with cirrhosis. METHODS: In a protein discovery cohort of 172 patients with cirrhosis or HCC, we screened for 481 proteins with suspension bead array or proximity extension assay...
April 5, 2023: Scandinavian Journal of Gastroenterology
Yuki Hamada, Kiyonori Tanoue, Yoshiaki Kita, Kan Tanabe, Kentaro Hokonohara, Masumi Wada, Yuto Hozaka, Hideyuki Oi, Chieri Nakayama, Michiyo Higashi, Takaaki Arigami, Shinichiro Mori, Takao Ohtsuka
PURPOSE: This study aims to investigate changes in the tumor immune environment of patients who underwent therapy with a vascular endothelial growth factor (VEGF) inhibitor for advanced colorectal cancer. METHODS: Patients ( n  = 135) with T3 or T4 colorectal cancer were included in this retrospective study. They were classified as follows: patients who had not received preoperative treatment (UPFRONT group, n  = 54), who had received FOLFOX as preoperative chemotherapy (FOLFOX group, n  = 55), and who had undergone resection after combination FOLFOX and bevacizumab as unresectable colorectal cancer (B-MAB group, n  = 26)...
March 29, 2023: Scandinavian Journal of Gastroenterology
Bjarki T Alexandersson, Luisa W Hugerth, Charlotte Hedin, Anna Forsberg, Nicholas J Talley, Lars Agreus, Ellionore Järbrink-Sehgal, Lars Engstrand, Anna Andreasson, Peter T Schmidt
BACKGROUND: The etiopathogenesis of diverticular disease is unknown. OBJECTIVE: To compare the fecal and mucosa-associated microbiota between participants with and without diverticulosis and participants who later developed diverticulitis versus those that did not from a population-based study. METHODS: The PopCol study, conducted in Stockholm, Sweden, invited a random sample of 3556 adults to participate, of which 745 underwent colonoscopy...
March 29, 2023: Scandinavian Journal of Gastroenterology
Renske W M Pauwels, S Ten Bokkel Huinink, Christien J van der Woude, M Doukas, L Oudijk, Annemarie C de Vries
BACKGROUND: Response evaluation after induction therapy with ustekinumab (UST) in Crohn's disease (CD) is important for decisions on maintenance therapy. We aimed to assess the potential of fecal calprotectin (FC) levels to predict endoscopic response at week 16. METHODS: CD patients with FC >100 µg/g and endoscopic active disease (SES-CD> 2, Rutgeerts' score ≥ i2) at initiation of UST therapy were enrolled. FC was determined at weeks 0, 2, 4, 8 and 16 and patients underwent a colonoscopy at week 16...
March 27, 2023: Scandinavian Journal of Gastroenterology
Bin Yang, Ping Yan, Xiacai Li, Huan Duan, Pinxiang Lu, Fei Jiang
BACKGROUND: colorectal endoscopic submucosal dissection (ESD) remains a technical challenge, but traction devices show promise in making this procedure easier. However, the efficacy of traction techniques for colorectal ESD is still unknown for inexperienced endoscopists. METHODS: We selected 400 patients who underwent colorectal ESD performed by four inexperienced endoscopists. Each patient in the traction-assisted ESD (TA-ESD) group was matched to a patient in the conventional ESD (C-ESD) group according to propensity scores...
March 20, 2023: Scandinavian Journal of Gastroenterology
Denong Liu, Lei Xu, Lei Chen, Jieqiong Hu, Danjuan Wu, Guanjun Wang, Haowei Shen, Xiaoqin Zhang, Yunxin Ji, Liemin Ruan, Zhongze Lou
BACKGROUND/AIMS: Gastro-oesophageal reflux disease (GORD) is a chronic high-morbidity disease with a bidirectional relationship with sleep disturbance (SD) that may occur via the transient receptor potential vanilloid type 1 receptor (TRPV1) in the oesophageal mucosa. Yet the related mechanism was still unclear, the aim of this study is to investigate whether TRPV1 is associated with the presence of SD in GORD patients. METHODS: A case-control study was performed...
March 16, 2023: Scandinavian Journal of Gastroenterology
(no author information available yet)
No abstract text is available yet for this article.
March 15, 2023: Scandinavian Journal of Gastroenterology
Tian Shi, Weidong Liu, Ting Li, Huan Liu, Wenjia Hui, Qiang Lin, Xiaojiang Han, Feng Gao
BACKGROUND: Celiac disease (CD) is an autoimmune small bowel disease. Genetic susceptibility for CD is mainly determined by the human leukocyte antigen (HLA)-DQ haplotypes. The risk of CD conferred by HLA genotypes varies geographically and across populations, however, this has not yet been documented in Chinese patients with CD. AIMS: To investigate the distribution of HLA-DQ and the related risks of CD development in Northwest China. METHODS: A total of 75 CD patients and 300 healthy individuals were genotyped for HLA-DQ using the Illumina NextSeq, and the relative risks of the different genotypes were evaluated...
May 2023: Scandinavian Journal of Gastroenterology
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