Journals Scandinavian Journal of Gastro...

Scandinavian Journal of Gastroenterology
Natasha Janko, Ammar Majeed, Isabella Commins, Paul Gow, William Kemp, Stuart K Roberts
BACKGROUND AND AIMS: Patients with cirrhosis of the liver are in a delicate state of rebalanced haemostasis and are at risk of developing both bleeding and thrombotic complications. Conventional haemostatic tests are unable to predict bleeding and thrombosis in these patients. We aimed to explore the role of Rotational Thromboelastometry (ROTEM) in predicting bleeding and thrombotic events in patients with cirrhosis. METHODS: We conducted a prospective cohort study of patients with cirrhosis at two metropolitan hospitals...
July 15, 2024: Scandinavian Journal of Gastroenterology
Tugba Guler, Ilknur Kulhas Celik, Anna Carina Ergani, Meltem Gumus, Halil Haldun Emiroglu, Hasibe Artac
AIM: Primary immunodeficiencies (PIDs) are a heterogeneous disorder group characterized by an impaired immune system, leading to an increased susceptibility to infections and a wide range of clinical manifestations, including gastrointestinal (GI) complications. This study aimed to assess the GI manifestations of PID patients and highlight the significance of atypical gastrointestinal symptoms in the early diagnosis of these patients. METHODS: A retrospective analysis was conducted on pediatric patients diagnosed with PIDs at Selcuk University Medical Faculty from 2011 to 2021...
July 15, 2024: Scandinavian Journal of Gastroenterology
Daniel Ansari, Kjetil Søreide, Bodil Andersson, Carsten Palnæs Hansen, Hanna Seppänen, Ernesto Sparrelid, Knut Jørgen Labori, Jakob Kirkegård, Saila Kauhanen, Christopher Månsson, Linn Såve Nymo, Minna Nortunen, Bergthor Björnsson, Antti Kivivuori, Bobby Tingstedt, Svein-Olav Bratlie, Kim Waardal, Johanna Laukkarinen, Asif Halimi, Hannes Lindberg, Håkan Olin, Roland Andersson
OBJECTIVES: Most patients with pancreatic cancer who have undergone surgical resection eventually develop disease recurrence. ‍This study aimed to investigate whether there is evidence to support routine surveillance after pancreatic cancer surgery, with a secondary aim of analyzing the implementation of surveillance strategies in the Nordic countries. MATERIALS AND METHODS: A scoping review was conducted to identify clinical practice guidelines globally and research studies relating to surveillance after pancreatic cancer resection...
July 12, 2024: Scandinavian Journal of Gastroenterology
Jesper Lexner, Spencer Clarkson, Klas Sjöberg
BACKGROUND: The incidence of celiac disease (CD) has increased rapidly in the late 20th and early 21st centuries, but there are recent reports of rates levelling off in countries with a high prevalence. The aim of this study was to investigate current trends in CD in southern Sweden. PATIENTS AND METHODS: Children and adults diagnosed with CD by biopsy or serology in the region of Skåne, southern Sweden, from 2010-2022 were included. The home address was identified through registers to analyze temporal and geographical trends...
July 12, 2024: Scandinavian Journal of Gastroenterology
Magnus Ploug, Niels Qvist, Birgitte Gade Jacobsen, Rasmus Kroijer, Jan Nielsen, Torben Knudsen
BACKGROUND AND OBJECTIVE: Iron deficiency affects more than 60% of colorectal cancer patients at the time of diagnosis. Iron deficiency ultimately leads to anemia, but additionally, iron deficiency might impact other domains of colorectal cancer patients' health and well-being. The aim of this study was to evaluate the impact of iron deficiency on fatigue, quality of life, cognition, and physical ability in patients undergoing evaluation for colorectal cancer. METHODS: Multicenter, prospective, observational cross-sectional study (2021-2023)...
July 10, 2024: Scandinavian Journal of Gastroenterology
Ingvild Farnes, Marius Lund-Iversen, Lars Aabakken, Caroline Verbeke, Knut Jørgen Labori
Background : International guidelines currently recommend the use of molecular testing in patients with advanced pancreatic cancer. The rate of actionable molecular alterations is low. The utility of molecular testing in patients with borderline resectable (BRPC) or locally advanced (LAPC) pancreatic cancer in real world clinical practice is unclear. Methods: 188 consecutive patients included in a prospective, population-based study (NORPACT-2) in patients with BRPC and LAPC (2018-2020) were reviewed. Molecular testing was performed at the discretion of the treating oncologist and was not recommended as a routine investigation by the national guidelines...
July 3, 2024: Scandinavian Journal of Gastroenterology
Tomohisa Iwai, Mitsuhiro Kida, Kosuke Okuwaki, Masafumi Watanabe, Kai Adachi, Junro Ishizaki, Taro Hanaoka, Akihiro Tamaki, Masayoshi Tadehara, Hiroshi Imaizumi, Chika Kusano
OBJECTIVES: Recently, artificial intelligence (AI) has been applied to clinical diagnosis. Although AI has already been developed for gastrointestinal (GI) tract endoscopy, few studies have applied AI to endoscopic ultrasound (EUS) images. In this study, we used a computer-assisted diagnosis (CAD) system with deep learning analysis of EUS images (EUS-CAD) and assessed its ability to differentiate GI stromal tumors (GISTs) from other mesenchymal tumors and their risk classification performance...
July 1, 2024: Scandinavian Journal of Gastroenterology
Nivi Kousgaard, Sofie Kuhlemeier Møllegaard Rasmussen, Sören Möller, Anastasios Koulaouzidis, Anders Mark-Christensen
BACKGROUND: The natural history of symptomatic uncomplicated gallstone disease is largely unknown. We examined the risk of progressing from symptomatic uncomplicated to complicated gallstone disease in a large regional cohort of patients, where disruptions in elective surgical capacities have led to the indefinite postponement of surgery for benign conditions, including cholecystectomies. METHODS: Patients with radiologically diagnosed incident symptomatic and uncomplicated gallstone disease were identified from outpatient clinics and emergency departments on the Island of Funen, Denmark...
July 1, 2024: Scandinavian Journal of Gastroenterology
Hanne Kjensli Hyldebrandt, Eli Marie Grindedal, Gert Huppertz-Hauss, Valeria Vitelli, Nora Johansen, Astrid Tenden Stormorken
BACKGROUND AND AIMS: Women with Lynch Syndrome (LS) have a high risk of colorectal and endometrial cancer. They are recommended regular colonoscopies, and some choose prophylactic hysterectomy. The aim of this study was to determine the impact of hysterectomy on subsequent colonoscopy in these women. MATERIALS AND METHODS: A total of 219 LS women >30 years of age registered in the clinical registry at Section for Hereditary Cancer, Oslo University Hospital, were included...
June 30, 2024: Scandinavian Journal of Gastroenterology
Sebastian Bonde Christiansen, Mark Andrew Ainsworth
BACKGROUND: Guidelines generally recommend a combination of immunological assays and chest X-ray imaging (CXR) when screening for latent tuberculosis infection (LTBI) prior to biologic treatment in inflammatory bowel disease (IBD). OBJECTIVE: To investigate whether CXR identify patients with suspected LTBI/TB who were not identified with QuantiFERON tests (QFT) when screening for LTBI/TB before starting biologic treatment in IBD patients. METHODS: Single-center, retrospective cohort study of patients with inflammatory bowel disease who had a QFT and a CXR prior to initiation of biologic treatment in a 5-year period (October 1st, 2017 to September 30th, 2022)...
June 22, 2024: Scandinavian Journal of Gastroenterology
Jingru Su, Liyuan Zhou, Jia Liu, Ying Wang, Guang Wang
OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD) is considered an independent risk factor for cardiovascular disease (CVD). The overall morbidity and mortality of CVD increase with higher fibrosis stage in NAFLD. Carotid atherosclerosis (CAS) is an important predictor of cardiovascular events. However, the relationship between liver fibrosis degree and the risk of CAS in NAFLD patients remains uncertain. We aimed to investigate the relationship between noninvasive liver fibrosis markers and CAS risk in patients with NAFLD...
June 22, 2024: Scandinavian Journal of Gastroenterology
Xing Long, Wu Liying, Li Zhuoran, Hu Yiheng, Wang Jinzhi, Zhang Xiaoling, Shou Yinxue, Cao Dandan, Zhu Liangsong
BACKGROUND AND AIM: To observe the clinical therapeutic effect and mental state of mindfulness-based cognitive therapy (MBCT) in patients with functional dyspepsia (FD). METHODS: In this study, 80 patients suffering from FD in an outpatient clinic were enrolled from January to December 2020. Patients were randomly allocated into the control group (conventional treatment) and observation group (MBCT treatment). Patients in the control group were prescribed rabeprazole and mosapiride, and patients in the observation group were given MBCT therapy in addition to the above drugs...
June 18, 2024: Scandinavian Journal of Gastroenterology
Heather Parr, Sean White, Claire Loversidge, Mohamed G Shiha, Suneil A Raju, Malik S El Atrash, Mark E McAlindon, Andrew D Hopper, Elizabeth A Williams, David S Sanders
BACKGROUND: When commencing enteral feeding, patients and families will want to know the likelihood of returning to an oral diet. There is a paucity of data on the prognosis of patients with gastrostomies. We describe a large dataset of patients, which identifies factors influencing gastrostomy removal and assesses the likelihood of the patient having at home enteral nutrition. METHODS: Retrospective data was collected on patients from Sheffield Teaching Hospitals who had received a gastrostomy and had outpatient enteral feeding between January 2016 and December 2019...
June 17, 2024: Scandinavian Journal of Gastroenterology
Kristin Ranheim Randel, Anna Lisa Schult, Edoardo Botteri, Mobina Nawaz, Dung Hong Nguyen, Øyvind Holme, Michael Bretthauer, Geir Hoff, Thomas de Lange
BACKGROUND AND STUDY AIMS: Long-time follow-up of sigmoidoscopy screening trials has shown reduced incidence and mortality of colorectal cancer (CRC), but inadequate bowel cleansing may hamper efficacy. The aim of this study was to assess the impact of bowel cleansing quality in sigmoidoscopy screening. PATIENTS AND METHODS: Individuals 50 to 74 years old who had a screening sigmoidoscopy in a population-based Norwegian, randomized trial between 2012 and 2019, were included in this cross-sectional study...
June 8, 2024: Scandinavian Journal of Gastroenterology
Kenichiro Okimoto, Tomoaki Matsumura, Naoki Akizue, Satsuki Takahashi, Ryosuke Horio, Chihiro Goto, Akane Kurosugi, Michiko Sonoda, Tatsuya Kaneko, Yuki Ohta, Takashi Taida, Keiko Saito, Keisuke Matsusaka, Jun Kato, Jun-Ichiro Ikeda, Naoya Kato
BACKGROUND: This study aimed to investigate the utility of intensive triamcinolone acetonide (TA) injections after extensive esophageal endoscopic submucosal dissection (ESD). METHODS: This retrospective study included 27 lesions in 27 consecutive patients who underwent ESD (ulcers encompassing ≥3/4 of the esophageal circumference) and received TA injections without oral steroid administration. Groups A and B included patients undergoing ESD with and without complete circumferential resection, respectively...
June 7, 2024: Scandinavian Journal of Gastroenterology
Eszter Bényei, Antonio Molinaro, Per Hedenström, Riadh Sadik
OBJECTIVE: Assessing unclear biliary strictures is challenging. We analyzed the diagnostic performance of radiology, EUS, and ERCP. METHODS: All patients referred for EUS and ERCP to assess an unclear biliary stricture were prospectively included. The data from radiology, EUS, ERCP, and tissue sampling were recorded. The diagnostic modalities were analyzed separately and in combination, with a focus on PSC. RESULTS: Between 2013 and 2020, 78 patients were included; 31% had PSC...
May 31, 2024: Scandinavian Journal of Gastroenterology
Satoshi Shinozaki, Hiroyuki Osawa, Yoshimasa Miura, Hirotsugu Sakamoto, Yoshikazu Hayashi, Tomonori Yano, Edward J Despott, Hironori Yamamoto
BACKGROUND: Gastroesophageal reflux disease (GERD) symptoms frequently recur after cessation of acid blockers. The presence of a hiatal hernia may worsen GERD symptoms and increase the risk of esophageal malignancy. The aim of this study is to clarify the timing and predictors for recurrence of GERD symptoms after cessation of vonoprazan (VPZ) therapy. METHODS: A retrospective observational study involved 86 patients who underwent cessation of VPZ therapy for symptomatic GERD...
May 31, 2024: Scandinavian Journal of Gastroenterology
Shaima Ramadan, Åsa Olsson, Olle Ekberg, Pamela Buchwald
INTRODUCTION: Conservative treatment of acute appendicitis is gaining popularity, and identifying patients with a higher risk of recurrence is becoming increasingly important. Previous studies have suggested that older age, male sex, diabetes, appendicolith and abscess formation may be contributing factors, however, results from the adult population are inconsistent. AIM: This study aims to identify predictive factors for recurrent appendicitis after conservative treatment...
May 30, 2024: Scandinavian Journal of Gastroenterology
Melissa Zarandi-Nowroozi, Mahsa Taghiakbari, Alan Barkun, Heiko Pohl, Bénédicte Nauche, Miguel Chagnon, Daniel von Renteln
BACKGROUND: Adenoma detection rate (ADR) is higher after a positive fecal immunochemical test (FIT) compared to direct screening colonoscopy. OBJECTIVE: This meta-analysis evaluated how ADR, the rates of advanced adenoma detection (AADR), colorectal cancer detection (CDR), and sessile serrated lesion detection (SSLDR) are affected by different FIT positivity thresholds. METHODS: We searched MEDLINE, EMBASE, CINAHL, and EBM Reviews databases for studies reporting ADR, AADR, CDR, and SSLDR according to different FIT cut-off values in asymptomatic average-risk individuals aged 50-74 years old...
May 22, 2024: Scandinavian Journal of Gastroenterology
Dun-Wei Yao, Min-Zhen Qin, Hai-Xing Jiang, Shan-Yu Qin
Objective: To quantitatively compare the diagnostic value of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) in solid pancreatic mass lesions using a systematic evaluation method. Methods: A systematic literature search was conducted on public databases to include studies comparing the diagnostic value of EUS-FNA and EUS-FNB in solid pancreatic mass lesions. The combined effect size was estimated using mean difference (MD) and risk difference (RD) respectively, and the corresponding 95% confidence interval (CI) was calculated...
May 20, 2024: Scandinavian Journal of Gastroenterology
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