journal
https://read.qxmd.com/read/38244172/one-year-results-of-treat-and-extend-regimen-with-intravitreal-faricimab-for-treatment-na%C3%A3-ve-neovascular-age-related-macular-degeneration
#21
JOURNAL ARTICLE
Hidetaka Matsumoto, Junki Hoshino, Kosuke Nakamura, Hideo Akiyama
PURPOSE: To evaluate 1-year outcomes of loading phase treatment followed by maintenance therapy using a treat-and-extend (TAE) regimen with intravitreal faricimab for neovascular age-related macular degeneration (nAMD). STUDY DESIGN: Retrospective, interventional case series. METHODS: We retrospectively studied 40 eyes of 38 consecutive patients with treatment-naïve nAMD, assessing best-corrected visual acuity (BCVA), foveal thickness, central choroidal thickness (CCT), total number of injections over 1 year, and intended injection interval at the last visit...
January 20, 2024: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/38163816/descemet-stripping-automated-endothelial-keratoplasty-via-a-frown-incision
#22
JOURNAL ARTICLE
Satoru Nakatani, Masahiro Yamaguchi, Satoshi Iwamoto
PURPOSE: To assess the outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) via a sclerocorneal frown incision. STUDY DESIGN: Retrospective comparative study. METHODS: The outcomes of Descement stripping endothelial keratoplasty (DSAEK) were retrospectively compared between 36 patients (36 eyes) who underwent surgery via a 3.8-mm frown incision (frown incision group) and 20 patients (20 eyes) who underwent surgery via a 4...
January 2024: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/38006466/relationship-between-strabismus-associated-with-angelman-syndrome-and-orbital-anomaly
#23
JOURNAL ARTICLE
Ayaka Yagasaki, Kiyofumi Mochizuki, Teiji Yagasaki, Hirokazu Sakaguchi
PURPOSE: To investigate the relationship between the details of strabismus and orbital abnormalities determined by ocular motility tests and orbital imaging examinations in 9 cases with Angelman syndrome (AS). STUDY DESIGN: A retrospective, clinical report. METHODS: The 9 AS cases (mean age at initial visit: 4.6 ± 8.0 years) were confirmed by genetic diagnosis of the chromosome 15q11-13 region. In all cases, axial imaging of the orbit in the transverse plane of the horizontal extraocular muscles was obtained...
January 2024: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37966564/intraocular-pressure-changes-at-different-gaze-positions-after-superior-rectus-muscle-lateral-rectus-muscle-loop-myopexy-in-highly-myopic-strabismus
#24
JOURNAL ARTICLE
Shinji Arai, Hiroko Suzuki, Shion Hayashi, Risako Inagaki, Takashi Haseoka, Akiko Hikoya, Miwa Komori, Tamami Shimizu, Yoshihiro Hotta, Miho Sato
PURPOSE: To evaluate changes in intraocular pressure (IOP) at different gaze positions before and after superior rectus muscle-lateral rectus muscle (SR-LR) loop myopexy in highly myopic strabismus (HMS). STUDY DESIGN: Nonrandomized clinical, prospective, interventional trial. METHODS: Fourteen patients with HMS (18 eyes) who underwent SR-LR loop myopexy were divided into 3 groups: < 100 prism diopters (PD) (mild esotropia [ET] group), > 100 PD (large ET group), and > 100 PD, and simultaneous recession of the medial rectus (MR) muscle was performed (large ET + MR group)...
January 2024: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/38085401/a-novel-bleb-revision-technique-lining-with-tenon-s-patch-graft-for-treatment-of-large-ischemic-leaking-blebs-with-severe-conjunctival-scarring-after-trabeculectomy
#25
JOURNAL ARTICLE
Tadamichi Akagi, Tetsuya Togano, Ryu Iikawa, Ryoko Igarashi, Mao Arimatsu, Makoto Miyajima, Yuta Sakaue, Takeo Fukuchi
PURPOSE: We report a new bleb lining technique with Tenon's patch graft for late-onset leakage from large ischemic bleb with severe conjunctival scarring and impractical conjunctival mobilization after trabeculectomy. STUDY DESIGN: Retrospective case series. METHODS: This study includes six cases with late-onset leakage from large ischemic blebs. Small Tenon's tissue is dissected from the incisional site or a previously made inferior incision for Tenon's anesthesia...
December 12, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/38070066/genotypes-and-clinical-features-of-rho-associated-retinitis-pigmentosa-in-a-japanese-population
#26
JOURNAL ARTICLE
Saki Tsutsui, Yusuke Murakami, Kohta Fujiwara, Yoshito Koyanagi, Masato Akiyama, Atsunobu Takeda, Yasuhiro Ikeda, Koh-Hei Sonoda
PURPOSE: To report the genotypes and clinical features of RHO-associated retinitis pigmentosa (RHO-RP) in the Kyushu region of Japan. STUDY DESIGN: Retrospective, single-center study. METHODS: Sixteen RP patients with pathogenic RHO variants seen at Kyushu University Hospital were investigated. Clinical data including age, best-corrected visual acuity (BCVA) in logarithm of the minimum angle of resolution (logMAR) units, visual field, fundus photography, and optical coherence tomography were retrospectively obtained...
December 9, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/38017339/clinical-features-of-26-cases-of-covid-19-associated-conjunctivitis
#27
JOURNAL ARTICLE
Asahi Tajima, Yukio Sassa, Daiki Ishio, Shota Yamashita, Eiji Sadashima, Rikki Arai, Kentaro Iwanaga, Shigeo Yoshida, Koh-Hei Sonoda, Hiroshi Enaida
PURPOSE: To explore the clinical features of COVID-19-associated conjunctivitis with the objective of preventing the spread of infection. STUDY DESIGN: Retrospective cohort study. METHODS: From March 2020 to March 2021, we retrospectively reviewed 26 (9.8%) consecutive COVID-19 patients with conjunctivitis among 282 COVID-19 cases admitted to our hospital. Clinical symptoms, onset date of conjunctivitis, time to patient recovery, and eye drop intervention were investigated...
November 29, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/38001368/corneal-refractive-error-and-astigmatism-in-patients-aged-6-to-18-years-with-a-history-of-retinopathy-of-prematurity-and-birth-weight-of-1500-g
#28
JOURNAL ARTICLE
Takako Tachikawa, Ritsuko Ueno, Tetsuko Mita, Daisuke Yuzurihara, Toru Noda
PURPOSE: To investigate corneal refractive power (CR) and astigmatism (AS) in 6- to 18-year-old children with a history of retinopathy of prematurity (ROP) and birth weight of <1500 g who either did or did not undergo retinal photocoagulation (PC). STUDY DESIGN: Retrospective study. METHODS: We examined 143 eyes of 77 children in 2021. The children were divided into three groups for evaluation of CR and AS: those with a birth weight of ≥2500 g (normal birth weight [NBW] group, 13 eyes) as controls, those with spontaneously resolved ROP (sr-ROP group, 27 eyes), and those who underwent PC for treatment of ROP (PC-ROP group, 103 eyes)...
November 25, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/38001367/vitreomacular-traction-in-diabetic-retinopathy
#29
JOURNAL ARTICLE
Yi-Ting Hsieh, Chung-May Yang
PURPOSE: Vitreomacular traction (VMT) has unique presentations in eyes with diabetic retinopathy (DR). This study aimed to investigate the characteristics and clinical course of VMT in DR. STUDY DESIGN: A retrospective case series. METHODS: Thirty eyes from 30 patients with DR and concurrent VMT were retrospectively enrolled. Baseline and final best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) characteristics were reported...
November 25, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37991608/correction-to-additive-effects-of%C3%A2-brimonidine-tartrate-0-1-brinzolamide-1-fixed%C3%A2-dose-combination-in%C3%A2-prostaglandin-analog%C3%A2-treated-japanese-glaucoma-patients
#30
Rei Sakata, Shiro Mizoue, Keiji Yoshikawa, Misato Adachi, Shinji Ohkubo, Naoki Hamada, Tomoko Naito, Tomoyuki Muramatsu, Takeshi Hara, Ryo Asato, Makoto Aihara
No abstract text is available yet for this article.
November 22, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37966565/measuring-macular-pigment-optical-density-using-reflective-images-of-confocal-scanning-laser-system
#31
JOURNAL ARTICLE
Hirofumi Morita, Itsuka Matsushita, Yoshihisa Fujino, Akira Obana, Hiroyuki Kondo
PURPOSE: To develop a method to measure the macular pigment optical density (MPOD) using scanning laser ophthalmoscopic images in young adults and children. STUDY DESIGN: Cross-sectional study. METHODS: Blue light reflectance fundus images of 32 healthy subjects were used. A profile of the linear reflectance changes across the center of the fovea on a grayscale fundus image was generated. The ratio of the macula-to-periphery reflection was designated as the peak value of the MPOD (MPOD[FR] ) based on established fundamentals...
November 15, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37966563/evaluation-of-anti-adenoviral-effects-of-the-polyvinyl-alcohol-iodine-ophthalmic-solution
#32
JOURNAL ARTICLE
Tomoko Tsukahara-Kawamura, Nozomu Hanaoka, Eiichi Uchio
PURPOSE: To investigate the virucidal effects of a polyvinyl alcohol iodine, Saniode, against 16 types of human mastadenovirus (HAdV) causing ophthalmic, respiratory, gastrointestinal, urinary, and systemic infections. STUDY DESIGN: Laboratory investigation METHODS: Fifty microliters of Saniode were exposed to 10 μL each containing HAdV virus stock solution of 1 × 106  copies/μL of HAdV-1, -2, -3, -4, 5, -6, -7, -8, -11, -37, -53, -54, -56, -64, -81, and -85 for 10 s, 30 s, 1 min, and 3 min...
November 15, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37947908/profiling-mirnas-in-tear-extracellular-vesicles-a-pilot-study-with-implications-for-diagnosis-of-ocular-diseases
#33
JOURNAL ARTICLE
Airu Torimura, Saki Kanei, Yumiko Shimizu, Takashi Baba, Ryu Uotani, Shin-Ichi Sasaki, Daisuke Nagase, Yoshitsugu Inoue, Takahiro Ochiya, Dai Miyazaki
PURPOSE: To estimate the roles of extracellular vesicles (EVs) in tears and to determine whether their profiles are associated with the type of ocular disease. STUDY DESIGN: Cross-sectional study. METHODS: Tear EVs were extracted from 14 healthy participants and from 21 patients with retinal diseases (age-related macular degeneration [AMD] or diabetic macular edema [DME]). The surface marker expression of tear EVs was examined, and microRNAs (miRNAs) were extracted and profiled by use of real-time PCR array...
November 10, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37945974/scientific-reviewers
#34
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
November 10, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37945975/correction-to-investigation-of-satisfaction-with-short%C3%A2-term-outcomes-after-switching-to-faricimab-to-treat-neovascular-age%C3%A2-related-macular-degeneration
#35
Taiichi Hikichi
No abstract text is available yet for this article.
November 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37861941/investigation-of-satisfaction-with-short-term-outcomes-after-switching-to-faricimab-to-treat-neovascular-age-related-macular-degeneration
#36
JOURNAL ARTICLE
Taiichi Hikichi
PURPOSE: To investigate the outcomes and patient satisfaction at 6-months' follow-up after switching to faricimab to treat neovascular age-related macular degeneration (nAMD) with a treat-and-extend (TAE) regimen. STUDY DESIGN: Retrospective observational study. METHODS: Forty-eight consecutive eyes (48 patients) were switched to faricimab to treat nAMD and followed for 6 months on a TAE regimen. The Macular Disease Treatment Satisfaction Questionnaire (MacTSQ) was administered to patients 6 months after the switch...
November 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37695434/clinical-presentations-of-acquired-comitant-esotropia-in-5-35-years-old-japanese-and-digital-device-usage-a-multicenter-registry-data-analysis-study
#37
JOURNAL ARTICLE
Hirohito Iimori, Sachiko Nishina, Osamu Hieda, Toshiaki Goseki, Noriko Nishikawa, Sadao Suzuki, Akiko Hikoya, Miwa Komori, Hiroko Suzuki, Tomoyo Yoshida, Shion Hayashi, Takafumi Mori, Akiko Kimura, Takeshi Morimoto, Yukiko Shimizu, Takashi Negishi, Tamami Shimizu, Yoshimi Yokoyama, Yoshiko Sugiyama, Noriyuki Azuma, Miho Sato
PURPOSE: To describe clinical presentations of acquired comitant esotropia and digital device use in children, adolescents, and young adults without neurological problems. STUDY DESIGN: Multicenter prospective observational study. METHODS: Patients with acquired comitant esotropia, without intracranial diseases aged 5-35 years at the time of visit, who were seen at pre-registered facilities within 1 year of onset were enrolled. The duration from the onset of symptoms and the time of digital device usage approximately 1 month before onset and their lifestyles were surveyed...
September 11, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37548816/assessment-of-myopic-rebound-effect-after-discontinuation-of-treatment-with-0-01-atropine-eye-drops-in-japanese-school-age-children
#38
RANDOMIZED CONTROLLED TRIAL
Osamu Hieda, Takahiro Hiraoka, Takashi Fujikado, Satoshi Ishiko, Satoshi Hasebe, Hidemasa Torii, Hiroshi Takahashi, Shiro Tanaka, Shigeru Kinoshita
PURPOSE: Having previously demonstrated the efficacy of 0.01% atropine eye drops for inhibiting progression of childhood myopia, we conducted additional analyses to assess post-treatment changes in myopia progression. STUDY DESIGN: Analysis of follow-up data from a previously reported randomized controlled trial METHODS: A mixed-effects model was used to compare intergroup changes in spherical equivalent (SE) and axial length (AL) at 1 month and 12 months after discontinuation of 2-year treatment with atropine or placebo in 167 school-age children...
September 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37603149/correction-to-a-novel-instrument-to-determine-hue-discrimination
#39
Mitsuru Sawa, Masaharu Mizuochi, Kazunori Matsumura, Makoto Aihara, Satoru Yamagami, Hidetoshi Yamashita, Toshikatsu Kaburaki
No abstract text is available yet for this article.
August 21, 2023: Japanese Journal of Ophthalmology
https://read.qxmd.com/read/37596444/additive-effects-of-brimonidine-tartrate-0-1-brinzolamide-1-fixed-dose-combination-in-prostaglandin-analog-treated-japanese-glaucoma-patients
#40
JOURNAL ARTICLE
Rei Sakata, Shiro Mizoue, Keiji Yoshikawa, Misato Adachi, Shinji Ohkubo, Naoki Hamada, Tomoko Naito, Tomoyuki Muramatsu, Takeshi Hara, Ryo Asato, Makoto Aihara
PURPOSE: A brimonidine tartrate 0.1%/brinzolamide 1% fixed-dose combination (BBFC) was recently approved for glaucoma and ocular hypertension treatment in Japan. We investigated the efficacy and safety of BBFC used concomitantly with prostaglandin analogs (PG) or a PG/beta-blocker fixed-dose combination (PG/beta FC). STUDY DESIGN: This was a prospective, open-label, multicenter study. PATIENTS AND METHODS: We enrolled Japanese patients with open-angle glaucoma...
August 19, 2023: Japanese Journal of Ophthalmology
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