journal
Journals Experimental Brain Research. E...

Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale

https://read.qxmd.com/read/38040856/the-ultrastructure-of-macaque-mesencephalic-trigeminal-nucleus-neurons
#1
JOURNAL ARTICLE
Niping Wang, Paul J May
Primary afferents originating from the mesencephalic trigeminal nucleus provide the main source of proprioceptive information guiding mastication, and thus represent an important component of this critical function. Unlike those of other primary afferents, their cell bodies lie within the central nervous system. It is believed that this unusual central location allows them to be regulated by synaptic input. In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate...
December 1, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/38015245/trunk-postural-reactions-to-the-force-perturbation-intensity-and-frequency-during-sitting-astride-in-children-with-cerebral-palsy
#2
JOURNAL ARTICLE
Shijun Yan, Seoung Hoon Park, Weena Dee, Renee Keefer, Ana-Marie Rojas, William Zev Rymer, Ming Wu
The purpose of this study was to examine kinematic and neuromuscular responses of the head and body to pelvis perturbations with different intensities and frequencies during sitting astride in children with CP. Sixteen children with spastic CP (mean age 7.4 ± 2.4 years old) were recruited in this study. A custom designed cable-driven robotic horse was used to apply controlled force perturbations to the pelvis during sitting astride. Each participant was tested in four force intensity conditions (i...
November 28, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/38015244/seasickness-susceptibility-and-the-vestibular-time-constant-a-prospective-study
#3
JOURNAL ARTICLE
Daniel Lagami, Yoni Evgeni Gutkovich, Anna Jamison, Yuri Fonar, Dror Tal
Human passive motion during boat, car or airplane travel may trigger motion sickness. Seasickness is the most provoking manifestation of motion sickness. It imposes major constraints on quality of life and human performance. Based on seasickness susceptibility the population is usually categorized into susceptible (S) and non-susceptible (NS). During repeated exposure some susceptible individuals undergo habituation and obtain symptoms relief, reflecting a third group of habituating (H) individuals. Recently, accumulative evidence suggests that the vestibular time constant (Tc) is associated with motion sickness susceptibility and attenuation of symptoms...
November 28, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/38015243/unravelling-the-parkinson-s-puzzle-from-medications-and-surgery-to-stem-cells-and-genes-a-comprehensive-review-of-current-and-future-management-strategies
#4
REVIEW
Krishnapriya Chandrababu, Vineeth Radhakrishnan, A S Anjana, Rahul Rajan, Unnikrishnan Sivan, Syam Krishnan, P S Baby Chakrapani
Parkinson's disease (PD) is a neurodegenerative disorder, prevalent in the elderly population. Neuropathological hallmarks of PD include loss of dopaminergic cells in the nigro-striatal pathway and deposition of alpha-synuclein protein in the neurons and synaptic terminals, which lead to a complex presentation of motor and non-motor symptoms. This review focuses on various aspects of PD, from clinical diagnosis to currently accepted treatment options, such as pharmacological management through dopamine replacement and surgical techniques such as deep brain stimulation (DBS)...
November 28, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/38010535/therapeutic-effect-of-intraperitoneal-dexamethasone-on-noise-induced-permanent-threshold-shift-in-mice-model
#5
JOURNAL ARTICLE
Byeonghyeon Lee, Min-Cheol Kim, Ye-Ri Kim, Jong-Heun Kim, Tae-Jun Kwon, Da Jung Jung, Un-Kyung Kim, Kyu-Yup Lee
The purpose of the study was to which investigate whether dexamethasone, which has anti-inflammatory and immune response suppression roles, could treat noise-induced hearing loss caused by damage to hair cells in the cochlea. The experiment used 8-week-old CBA mice exposed to white noise at an intensity of 110 dB SPL for 2 h, with hearing loss confirmed by the auditory brainstem response test. Dexamethasone was administered by intraperitoneal injection for 5 days, and the therapeutic effect was investigated for 3 weeks...
November 27, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/38006421/back-and-front-peripersonal-space-behavioural-and-emg-evidence-of-top-down-and-bottom-up-mechanisms
#6
JOURNAL ARTICLE
Gianna Cocchini, Daniel Müllensiefen, Ruggero Platania, Chiara Niglio, Enrica Tricomi, Laura Veronelli, Elda Judica
Previous studies have identified a 'defensive graded field' in the peripersonal front space where potential threatening stimuli induce stronger blink responses, mainly modulated by top-down mechanisms, which include various factors, such as proximity to the body, stimulus valence, and social cues. However, very little is known about the mechanisms responsible for representation of the back space and the possible role of bottom-up information. By means of acoustic stimuli, we evaluated individuals' representation for front and back space in an ambiguous environment that offered some degree of uncertainty in terms of both distance (close vs...
November 25, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37999725/impairment-of-the-internal-forward-model-and-feedback-mechanisms-for-vocal-sensorimotor-control-in-post-stroke-aphasia-evidence-from-directional-responses-to-altered-auditory-feedback
#7
JOURNAL ARTICLE
Zeinab Khoshhal Mollasaraei, Roozbeh Behroozmand
The present study examined opposing and following vocal responses to altered auditory feedback (AAF) to determine how damage to left-hemisphere brain networks impairs the internal forward model and feedback mechanisms in post-stroke aphasia. Forty-nine subjects with aphasia and sixty age-matched controls performed speech vowel production tasks while their auditory feedback was altered using randomized ± 100 cents upward and downward pitch-shift stimuli. Data analysis revealed that when vocal responses were averaged across all trials (i...
November 24, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37994917/the-role-of-engagement-and-arousal-in-emotion-regulation-an-eeg-study
#8
JOURNAL ARTICLE
Vladimir Kosonogov, Ioannis Ntoumanis, Gullu Hajiyeva, Iiro Jääskeläinen
Cognitive reappraisal and expressive suppression are well-studied strategies of emotion regulation (ER). However, the results on their physiological basis are controversial. While in some studies, ER was accompanied by the inhibition of the nervous system, others suggested that ER even might increase arousal and engagement. We calculated the inter-subject correlation (ISC) and indices of engagement, valence and arousal of EEG during suppression, reappraisal, or natural watching of neutral and negative videos...
November 23, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37994916/voluntary-running-wheel-exercise-induces-cognitive-improvement-post-traumatic-brain-injury-in-mouse-model-through-redressing-aberrant-excitation-regulated-by-voltage-gated-sodium-channels-1-1-1-3-and-1-6
#9
JOURNAL ARTICLE
Dan Wang, Hui-Xiang Zhang, Guo-Ji Yan, Hao-Ran Zhao, Xiao-Han Dong, Ya-Xin Tan, Shan Li, Min-Nan Lu, Rong Mei, Li-Na Liu, Xu-Yang Wang, Yan-Bin Xiyang
Traumatic brain injury (TBI) leads to disturbed brain discharge rhythm, elevated excitability, anxiety-like behaviors, and decreased learning and memory capabilities. Cognitive dysfunctions severely affect the quality of life and prognosis of TBI patients, requiring effective rehabilitation treatment. Evidence indicates that moderate exercise after brain injury decreases TBI-induced cognitive decline. However, the underlying mechanism remains unelucidated. Our results demonstrate that TBI causes cognitive impairment behavior abnormalities and overexpression of Nav1...
November 23, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37994915/reducing-alertness-does-not-affect-line-bisection-bias-in-neurotypical-participants
#10
JOURNAL ARTICLE
Stefan Smaczny, Dominik Bauder, Christoph Sperber, Hans-Otto Karnath, Bianca de Haan
Alertness, or one's general readiness to respond to stimulation, has previously been shown to affect spatial attention. However, most of this previous research focused on speeded, laboratory-based reaction tasks, as opposed to the classical line bisection task typically used to diagnose deficits of spatial attention in clinical settings. McIntosh et al. (Cogn Brain Res 25:833-850, 2005) provide a form of line bisection task which they argue can more sensitively assess spatial attention. Ninety-eight participants were presented with this line bisection task, once with and once without spatial cues, and both before and after a 50-min vigilance task that aimed to decrease alertness...
November 23, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37987808/perceived-cognitive-fatigue-has-only-marginal-effects-on-static-balance-control-in-healthy-young-adults
#11
JOURNAL ARTICLE
Kerstin Weissinger, Margit Midtgaard Bach, Anna Brachman, John F Stins, Peter Jan Beek
We examined the influence of perceived cognitive fatigue on static balance control in healthy young adults to gain greater clarity about this issue than provided in previous research. Based on the prevailing assumption in pertinent literature, we hypothesized that the influence of cognitive fatigue on balance control depends on the attentional effort required by the balance tasks being performed. To test this hypothesis, 44 young adults (24 women and 20 men) were alternately assigned to either the experimental group that was cognitively fatigued (using the 16-min TloadDback-task with individualized settings) or the control group (who watched a documentary)...
November 21, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37979067/the-topographical-attenuation-of-cutaneous-input-is-modulated-at-the-ankle-joint-during-gait
#12
JOURNAL ARTICLE
Kelly A Robb, Stephen D Perry
The attenuation of sensory inputs via various methods has been demonstrated to impair balance control and alter locomotor behavior during human walking; however, the effects of attenuating foot sole sensation under distinct areas of the foot sole on lower extremity motor output remains poorly understood. Thus, the purpose of this study was to attenuate cutaneous feedback via regional hypothermia under five different areas of the foot sole and investigate the resultant modulation of kinematic and muscle activity during level walking...
November 18, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37979066/facilitated-adaptation-via-structural-learning-increases-bimanual-interference
#13
JOURNAL ARTICLE
Alexander T Brunfeldt, Phillip C Desrochers, Florian A Kagerer
Bimanual coordination is an essential feature of the motor system, yet interactions between the limbs during independent control remain poorly understood. Interference between the two hands, or the assimilation of movement characteristics between the two effectors, can be induced by perturbing one arm (e.g., via visuomotor rotation) and then measuring the effects in the contralateral limb. In this study, we sought to further determine the role adaptation plays in bimanual interference using a structural learning paradigm to alter feedback regulation in reaching...
November 18, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37978080/exploring-eeg-resting-state-as-a-function-of-boredom-proneness-in-pre-adolescents-and-adolescents
#14
JOURNAL ARTICLE
Jamie Nettinga, Sarah Naseem, Ofir Yakobi, Teena Willoughby, James Danckert
Boredom is a prominent experience commonly reported in school settings and associated with poor academic achievement. Little is known, however, about the age-related trajectory of boredom. Here we examined self-reported ratings of boredom in a cross-sectional sample of 8 to 15-year olds (n = 185) as a function of resting state EEG. Results indicated that reports of boredom in school rose as a function of age. Resting state EEG showed a decrease in theta power with age perhaps reflective of increased control...
November 17, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37973625/the-p38mapk-atf2-signaling-pathway-is-involved-in-pnd-in-mice
#15
JOURNAL ARTICLE
Mengjiao Zhu, Si Long, Yizhi Tao, Zhifa Zhang, Zhiqiang Zhou, Xueren Wang, Wei Chen
Accumulating evidence indicates that microglia-mediated neuroinflammation in the hippocampus contributes to the development of perioperative neurocognitive disorder (PND). P38MAPK, a point of convergence for different signaling processes involved in inflammation, can be activated by various stresses. This study aims to investigate the role of the P38MAPK/ATF2 signaling pathway in the development of PND in mice. Aged C57BL/6 mice were subjected to tibial fracture surgery under isoflurane anesthesia to establish a PND animal model...
November 16, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37966504/changes-in-vestibular-related-responses-to-combined-noisy-galvanic-vestibular-stimulation-and-cerebellar-transcranial-direct-current-stimulation
#16
JOURNAL ARTICLE
Tsubasa Mitsutake, Hisato Nakazono, Tomoyuki Shiozaki, Daisuke Fujita, Maiko Sakamoto
Vestibular nuclei and cerebellar function comprise vestibular neural networks that control vestibular-related responses. However, the vestibular-related responses to simultaneous stimulation of these regions are unclear. This study aimed to examine whether the combination of noisy galvanic vestibular stimulation (nGVS) and cerebellar transcranial direct current stimulation (ctDCS) using a complex transcranial electrical stimulation device alters vestibular-dominant standing stability and vestibulo-ocular reflex (VOR) function...
November 15, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37962638/the-effect-and-efficiency-of-attentional-networks-and-the-brain-electrophysiology
#17
JOURNAL ARTICLE
Hossein Akbari-Lalimi, Shahrokh Naseri, Mahdi Momennezhad, Hoda Zare, Ali Talaei, Seyed Ali Shafiei
The attention networks test (ANT) is frequently utilized to evaluate executive, alerting, and orienting attentional components. Additionally, it serves as an activation task in neuroimaging studies. This study aimed to examine the relationship between attention networks and brain electrophysiology. The study enrolled 40 right-handed male students (age = 20.8 ± 1.3 years) who underwent the revised attention network test, while their electroencephalogram signals were recorded...
November 14, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37955707/transcranial-direct-current-stimulation-facilitates-backward-walking-training
#18
JOURNAL ARTICLE
Ayuka Sasaki, Anri Aisawa, Naoyuki Takeuchi
Backward walking training presents a great challenge to the physical and neural systems, which may result in an improvement in gait performance. Transcranial direct current electrical stimulation (tDCS), which can non-invasively enhance cortical activity, has been reported to strengthen corticomotor plasticity. We investigated whether excitatory tDCS over the primary motor cortex (M1) or the dorsolateral prefrontal cortex (DLPFC) enhances the effects of backward walking training in healthy participants. Thirty-six healthy participants (16 men and 20 women, mean age 21...
November 13, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37955706/the-effects-of-periodic-and-noisy-tendon-vibration-on-a-kinesthetic-targeting-task
#19
JOURNAL ARTICLE
Gregg Eschelmuller, Annika Szarka, Braelyn Gandossi, J Timothy Inglis, Romeo Chua
Tendon vibration is used extensively to assess the role of peripheral mechanoreceptors in motor control, specifically, the muscle spindles. Periodic tendon vibration is known to activate muscle spindles and induce a kinesthetic illusion that the vibrated muscle is longer than it actually is. Noisy tendon vibration has been used to assess the frequency characteristics of proprioceptive reflex pathways during standing; however, it is unknown if it induces the same kinesthetic illusions as periodic vibration. The purpose of the current study was to assess the effects of both periodic and noisy tendon vibration in a kinesthetic targeting task...
November 13, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/37947851/effects-of-sensory-modality-and-task-relevance-on-omitted-stimulus-potentials
#20
JOURNAL ARTICLE
Tomomi Ishida, Hiroshi Nittono
Omitted stimulus potentials (OSPs) occur when a sensory stimulus is unexpectedly omitted. They are thought to reflect predictions about upcoming sensory events. The present study examined how OSPs differ across the sensory modalities of predicted stimuli. Twenty-nine university students were asked to press a mouse button at a regular interval of 1-2 s, which was immediately followed by either a visual or auditory stimulus in different blocks. The stimuli were sometimes omitted (p = 0.2), to which event-related potentials (ERPs) were recorded...
November 10, 2023: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
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