Liang Zhang, Pradeep Kumar Prabhakar, Vivek S Bharadwaj, Yannick J Bomble, Maria J Peña, Breeanna R Urbanowicz
Glycosyltransferases (GTs) are carbohydrate-active enzymes that are encoded by the genomes of organisms spanning all domains of life. GTs catalyze glycosidic bond formation, transferring a sugar monomer from an activated donor to an acceptor substrate, often another saccharide. GTs from family 47 (GT47, PF03016) are involved in the synthesis of complex glycoproteins in mammals and insects and play a major role in the synthesis of almost every class of polysaccharide in plants, with the exception of cellulose, callose, and mixed linkage β-1,3/1,4-glucan...
April 14, 2023: Essays in Biochemistry