journal
https://read.qxmd.com/read/38862783/supra-structures-to-target-lipid-ii
#1
JOURNAL ARTICLE
Andrea Du Toit
No abstract text is available yet for this article.
June 11, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38831030/eskape-pathogens-antimicrobial-resistance-epidemiology-clinical-impact-and-therapeutics
#2
REVIEW
William R Miller, Cesar A Arias
The rise of antibiotic resistance and a dwindling antimicrobial pipeline have been recognized as emerging threats to public health. The ESKAPE pathogens - Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter spp. - were initially identified as critical multidrug-resistant bacteria for which effective therapies were rapidly needed. Now, entering the third decade of the twenty-first century, and despite the introduction of several new antibiotics and antibiotic adjuvants, such as novel β-lactamase inhibitors, these organisms continue to represent major therapeutic challenges...
June 3, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38811839/co-evolution-of-early-earth-environments-and-microbial-life
#3
REVIEW
Timothy W Lyons, Christopher J Tino, Gregory P Fournier, Rika E Anderson, William D Leavitt, Kurt O Konhauser, Eva E Stüeken
Two records of Earth history capture the evolution of life and its co-evolving ecosystems with interpretable fidelity: the geobiological and geochemical traces preserved in rocks and the evolutionary histories captured within genomes. The earliest vestiges of life are recognized mostly in isotopic fingerprints of specific microbial metabolisms, whereas fossils and organic biomarkers become important later. Molecular biology provides lineages that can be overlayed on geologic and geochemical records of evolving life...
May 29, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38789668/foodborne-bacterial-pathogens-genome-based-approaches-for-enduring-and-emerging-threats-in-a-complex-and-changing-world
#4
REVIEW
Alison E Mather, Matthew W Gilmour, Stuart W J Reid, Nigel P French
Foodborne illnesses pose a substantial health and economic burden, presenting challenges in prevention due to the diverse microbial hazards that can enter and spread within food systems. Various factors, including natural, political and commercial drivers, influence food production and distribution. The risks of foodborne illness will continue to evolve in step with these drivers and with changes to food systems. For example, climate impacts on water availability for agriculture, changes in food sustainability targets and evolving customer preferences can all have an impact on the ecology of foodborne pathogens and the agrifood niches that can carry microorganisms...
May 24, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38778224/the-gut-airway-microbiome-axis-in-health-and-respiratory-diseases
#5
REVIEW
Mustafa Özçam, Susan V Lynch
Communication between the gut and remote organs, such as the brain or the cardiovascular system, has been well established and recent studies provide evidence for a potential bidirectional gut-airway axis. Observations from animal and human studies indicate that respiratory insults influence the activity of the gut microbiome and that microbial ligands and metabolic products generated by the gut microbiome shape respiratory immunity. Information exchange between these two large mucosal surface areas regulates microorganism-immune interactions, with significant implications for the clinical and treatment outcomes of a range of respiratory conditions, including asthma, chronic obstructive pulmonary disease and lung cancer...
May 22, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38773353/defending-against-plasmids
#6
JOURNAL ARTICLE
Andrea Du Toit
No abstract text is available yet for this article.
May 21, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38769461/fat-desulfovibrio-and-cancer
#7
JOURNAL ARTICLE
Agustina Taglialegna
No abstract text is available yet for this article.
May 20, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38769460/breaking-through-the-concept-barrier-to-develop-broad-spectrum-antiviral-counter-measures
#8
JOURNAL ARTICLE
Yi Shi
No abstract text is available yet for this article.
May 20, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38769459/discovering-molecular-paradigms-of-microbial-carcinogenesis
#9
JOURNAL ARTICLE
Carrie L Shaffer
No abstract text is available yet for this article.
May 20, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38755479/tracking-pathogen-evolution-through-climate-change
#10
JOURNAL ARTICLE
Lia Bote, Mailis Maes
No abstract text is available yet for this article.
May 16, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38750252/viruses-on-the-move
#11
JOURNAL ARTICLE
Andrea Du Toit
No abstract text is available yet for this article.
May 15, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38730102/a-mosquito-symbiont-controls-flaviviruses
#12
JOURNAL ARTICLE
Agustina Taglialegna
No abstract text is available yet for this article.
May 10, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38730101/bacteriocin-diversity-function-discovery-and-application-as-antimicrobials
#13
REVIEW
Ivan Sugrue, R Paul Ross, Colin Hill
Bacteriocins are potent antimicrobial peptides that are produced by bacteria. Since their discovery almost a century ago, diverse peptides have been discovered and described, and some are currently used as commercial food preservatives. Many bacteriocins exhibit extensively post-translationally modified structures encoded on complex gene clusters, whereas others have simple linear structures. The molecular structures, mechanisms of action and resistance have been determined for a number of bacteriocins, but most remain incompletely characterized...
May 10, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38689039/ecological-and-evolutionary-mechanisms-driving-within-patient-emergence-of-antimicrobial-resistance
#14
REVIEW
Matthew J Shepherd, Taoran Fu, Niamh E Harrington, Anastasia Kottara, Kendall Cagney, James D Chalmers, Steve Paterson, Joanne L Fothergill, Michael A Brockhurst
The ecological and evolutionary mechanisms of antimicrobial resistance (AMR) emergence within patients and how these vary across bacterial infections are poorly understood. Increasingly widespread use of pathogen genome sequencing in the clinic enables a deeper understanding of these processes. In this Review, we explore the clinical evidence to support four major mechanisms of within-patient AMR emergence in bacteria: spontaneous resistance mutations; in situ horizontal gene transfer of resistance genes; selection of pre-existing resistance; and immigration of resistant lineages...
April 30, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38658789/the-complex-life-of-the-hiv-1-full-length-rna
#15
JOURNAL ARTICLE
Ricardo Soto-Rifo
No abstract text is available yet for this article.
June 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38658788/nitroplast-organelle-unveiled
#16
JOURNAL ARTICLE
Ashley York
No abstract text is available yet for this article.
April 24, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38658787/mycetocola-to-the-rescue
#17
JOURNAL ARTICLE
Agustina Taglialegna
No abstract text is available yet for this article.
April 24, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38649748/phages-get-snappy
#18
JOURNAL ARTICLE
Andrea Du Toit
No abstract text is available yet for this article.
April 22, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38637715/shaking-up-that-sick-feeling-with-biofilm-sugars
#19
JOURNAL ARTICLE
Agustina Taglialegna
No abstract text is available yet for this article.
April 18, 2024: Nature Reviews. Microbiology
https://read.qxmd.com/read/38622352/covid-19-drug-discovery-and-treatment-options
#20
REVIEW
Jasper Fuk-Woo Chan, Shuofeng Yuan, Hin Chu, Siddharth Sridhar, Kwok-Yung Yuen
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused substantial morbidity and mortality, and serious social and economic disruptions worldwide. Unvaccinated or incompletely vaccinated older individuals with underlying diseases are especially prone to severe disease. In patients with non-fatal disease, long COVID affecting multiple body systems may persist for months. Unlike SARS-CoV and Middle East respiratory syndrome coronavirus, which have either been mitigated or remained geographically restricted, SARS-CoV-2 has disseminated globally and is likely to continue circulating in humans with possible emergence of new variants that may render vaccines less effective...
April 15, 2024: Nature Reviews. Microbiology
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