journal
https://read.qxmd.com/read/38635470/barriers-and-enablers-to-exercise-adherence-in-people-with-nonspecific-chronic-low-back-pain-a-systematic-review-of-qualitative-evidence
#1
JOURNAL ARTICLE
Yannick L Gilanyi, Brishna Shah, Aidan G Cashin, Mitchell T Gibbs, Jessica Bellamy, Richard Day, James H McAuley, Matthew D Jones
Exercise is a first-line treatment for chronic low back pain (CLBP), reducing pain and disability in the short term. However, exercise benefits decrease over time, with a lack of long-term exercise adherence a potential reason for this. This study aimed to synthesize the perceptions and beliefs of individuals with CLBP and identify their barriers and enablers to exercise adherence. We searched CENTRAL, Embase, CINAHL, SPORTDiscus, PubMed, PsycINFO, and Scopus databases from inception to February 28, 2023, for qualitative studies that explored the factors influencing exercise adherence for people with CLBP...
April 16, 2024: Pain
https://read.qxmd.com/read/38635468/painful-distortions-people-with-painful-knee-osteoarthritis-have-biased-visuospatial-perception-of-the-environment
#2
JOURNAL ARTICLE
Erin MacIntyre, Felicity A Braithwaite, Tasha R Stanton
Visuospatial perception is thought to be adaptive-ie, hills are perceived as steeper when capacity is low, or threat is high-guiding appropriate interaction with the environment. Pain (bodily threat) may similarly modulate visuospatial perception, with the extent of modulation influenced by threat magnitude (pain intensity, fear) and associated with behaviour (physical activity). We compared visuospatial perception of the environment between 50 people with painful knee osteoarthritis and 50 age-/sex-matched pain-free control participants using 3 virtual reality tasks (uphill steepness estimation, downhill steepness estimation, and a distance-on-hill measure), exploring associations between visuospatial perception, clinical characteristics (pain intensity, state and trait fear), and behaviour (wrist-worn accelerometry) within a larger knee osteoarthritis group (n = 85)...
April 16, 2024: Pain
https://read.qxmd.com/read/38635466/people-with-painful-knee-osteoarthritis-hold-negative-implicit-attitudes-towards-activity
#3
JOURNAL ARTICLE
Brian W Pulling, Felicity A Braithwaite, Joanne Mignone, David S Butler, J P Caneiro, Ottmar V Lipp, Tasha R Stanton
Negative attitudes/beliefs surrounding osteoarthritis, pain, and activity contribute to reduced physical activity in people with knee osteoarthritis (KOA). These attitudes/beliefs are assessed using self-report questionnaires, relying on information one is consciously aware of and willing to disclose. Automatic (ie, implicit) assessment of attitudes does not rely on conscious reflection and may identify features unique from self-report. We developed an implicit association test that explored associations between images of a person moving/twisting their knee (activity) or sitting/standing (rest), and perceived threat (safe vs dangerous)...
April 16, 2024: Pain
https://read.qxmd.com/read/38598349/blocking-proteinase-activated-receptor-2-signaling-relieves-pain-suppresses-nerve-sprouting-improves-tissue-repair-and-enhances-analgesic-effect-of-b-vitamins-in-rats-with-achilles-tendon-injury
#4
JOURNAL ARTICLE
Lihui Li, Hongyu Yao, Rufan Mo, Lihong Xu, Peng Chen, Yuchen Chen, Jiang-Jian Hu, Wei Xie, Xue-Jun Song
Tendon injury produces intractable pain and disability in movement, but the medications for analgesia and restoring functional integrity of tendon are still limited. In this study, we report that proteinase-activated receptor 2 (PAR2) activation in dorsal root ganglion (DRG) neurons contributes to chronic pain and tendon histopathological changes produced by Achilles tendon partial transection injury (TTI). Tendon partial transection injury increases the expression of PAR2 protein in both somata of DRG neurons and their peripheral terminals within the injured Achilles tendon...
April 9, 2024: Pain
https://read.qxmd.com/read/38595206/nociplastic-pain-mechanisms-and-toll-like-receptors-as-promising-targets-for-its-management
#5
JOURNAL ARTICLE
Erick J Rodríguez-Palma, Saul Huerta de la Cruz, Ana M Islas-Espinoza, Gabriela Castañeda-Corral, Vinicio Granados-Soto, Rajesh Khanna
Nociplastic pain, characterized by abnormal pain processing without an identifiable organic cause, affects a significant portion of the global population. Unfortunately, current pharmacological treatments for this condition often prove ineffective, prompting the need to explore new potential targets for inducing analgesic effects in patients with nociplastic pain. In this context, toll-like receptors (TLRs), known for their role in the immune response to infections, represent promising opportunities for pharmacological intervention because they play a relevant role in both the development and maintenance of pain...
April 5, 2024: Pain
https://read.qxmd.com/read/38595202/pediatric-chronic-pain-grading-a-revised-classification-of-the-severity-of-pediatric-chronic-pain
#6
JOURNAL ARTICLE
Susanne Grothus, Ariane Sommer, Lorin Stahlschmidt, Gerrit Hirschfeld, Lea Höfel, Roland Linder, Boris Zernikow, Julia Wager
In this study, we describe the development and validation of a revised Pediatric Chronic Pain Grading (P-CPG) for children aged 8 to 17 years that adds emotional impairment to previously used measures of pain intensity and functional impairment. Such a measure enables the assessment of chronic pain severity in different epidemiological and clinical populations, the stratification of treatment according to pain severity, and the monitoring of treatment outcome. The P-CPG was developed using a representative sample of school children with chronic pain (n = 454; Mage = 12...
April 5, 2024: Pain
https://read.qxmd.com/read/38595183/top-down-attention-does-not-modulate-mechanical-hypersensitivity-consecutive-to-central-sensitization-insights-from-an-experimental-analysis
#7
JOURNAL ARTICLE
Delia Della Porta, Eléonore Scheirman, Valéry Legrain
According to the neurocognitive model of attention to pain, when the attentional resources invested in a task unrelated to pain are high, limited cognitive resources can be directed toward the pain. This is supported by experimental studies showing that diverting people's attention away from acute pain leads to experiencing less pain. Theoretical work has suggested that this phenomenon may present a top-down modulatory mechanism for persistent pain as well. However, conclusive empirical evidence is lacking...
April 3, 2024: Pain
https://read.qxmd.com/read/38564185/biomarkers-of-stress-as-mind-body-intervention-outcomes-for-chronic-pain-an-evaluation-of-constructs-and-accepted-measurement
#8
JOURNAL ARTICLE
Sarah Nelson, Morgan Mitcheson, Bridget Nestor, Michelle Bosquet Enlow, David Borsook
No abstract text is available yet for this article.
April 2, 2024: Pain
https://read.qxmd.com/read/38564184/uncovering-moderators-of-pain-perception-by-women-with-endometriosis-from-latin-america-and-spain-the-roles-of-sociodemographics-racial-self-identity-and-pain-catastrophizing
#9
JOURNAL ARTICLE
Idhaliz Flores, Annelyn Torres-Reverón, Eduardo Navarro, Cristina I Nieves-Vázquez, Ariana C Cotto-Vázquez, Joanne M Alonso-Díaz, Nabal J Bracero, Katy Vincent
A cross-sectional multinational collaborative study on women with endometriosis from Latin America and Spain uncovered high levels of painful symptomatology and high pain catastrophizing scores. Associations between pain perception/catastrophizing and race/ethnicity have been documented. This study was conducted to uncover factors moderating pelvic pain severity, including socioeconomic variables, self-identified race, and pain catastrophizing in women with endometriosis from Latin America and Spain, a population encompassing diverse racial and sociocultural contexts...
April 2, 2024: Pain
https://read.qxmd.com/read/38563996/subgroups-of-pelvic-pain-are-differentially-associated-with-endometriosis-and-inflammatory-comorbidities-a-latent-class-analysis
#10
JOURNAL ARTICLE
Marzieh Ghiasi, Chi Chang, Amy L Shafrir, Allison F Vitonis, Naoko Sasamoto, Ana I Vazquez, Amy D DiVasta, Kristen Upson, Christine B Sieberg, Kathryn L Terry, Claudia B Holzman, Stacey A Missmer
Chronic pelvic pain is heterogeneous with potentially clinically informative subgroups. We aimed to identify subgroups of pelvic pain based on symptom patterns and investigate their associations with inflammatory and chronic pain-related comorbidities. Latent class analysis (LCA) identified subgroups of participants (n = 1255) from the Adolescence to Adulthood (A2A) cohort. Six participant characteristics were included in the LCA: severity, frequency, and impact on daily activities of both menstruation-associated (cyclic) and non-menstruation-associated (acyclic) pelvic pain...
April 2, 2024: Pain
https://read.qxmd.com/read/38563989/patterns-of-physiotherapy-attendance-in-compensated-australian-workers-with-low-back-pain-a-retrospective-cohort-study
#11
JOURNAL ARTICLE
Michael Di Donato, Luke R Sheehan, Ross Iles, Shannon Gray, Rachelle Buchbinder, Alex Collie
Workers with low back pain (LBP) frequently seek care from physiotherapists. We sought to identify patterns of physiotherapy attendance and factors associated with these patterns in Australian workers with accepted compensation claims for LBP. We included workers with accepted workers' compensation claims for LBP from 4 Australian states between 2011 and 2015. We used trajectory modelling to identify distinct groups of workers based on the number (ie, volume) of monthly physiotherapy attendances over a 2-year period from claim acceptance...
April 2, 2024: Pain
https://read.qxmd.com/read/38551888/mechanical-pain-sensitivity-is-associated-with-hippocampal-structural-integrity
#12
JOURNAL ARTICLE
Lizbeth J Ayoub, Liat Honigman, Alexander J Barnett, Mary Pat McAndrews, Massieh Moayedi
Rodents and human studies indicate that the hippocampus, a brain region necessary for memory processing, responds to noxious stimuli. However, the hippocampus has yet to be considered a key brain region directly involved in the human pain experience. One approach to answer this question is to perform quantitative sensory testing on patients with hippocampal damage-ie, medial temporal lobe epilepsy. Some case studies and case series have performed such tests in a handful of patients with various types of epilepsy and have reported mixed results...
March 28, 2024: Pain
https://read.qxmd.com/read/38537057/involvement-of-propriospinal-processes-in-conditioned-pain-modulation
#13
JOURNAL ARTICLE
Hadas Nahman-Averbuch, Mathieu Piché, Kirsty Bannister, Robert C Coghill
No abstract text is available yet for this article.
March 27, 2024: Pain
https://read.qxmd.com/read/38537052/the-sociocultural-context-of-adolescent-pain-portrayals-of-pain-in-popular-adolescent-media
#14
JOURNAL ARTICLE
Allison Cormier, Kendra Mueri, Maria Pavlova, Anna Hood, Queenie Li, Idia Thurston, Abbie Jordan, Melanie Noel
Research has consistently suggested that media consumption plays a vital role in children's socialization, including the socialization of painful experiences. Past research examining young children's popular media revealed worrisome trends in media depictions of pain; it consisted of narrow depictions of pain, gender stereotypes, and an overwhelming lack of empathy from observers, which could contribute to pain-related stigma. Research has not yet examined how pain is portrayed in adolescent media, despite adolescence being the developmental period when chronic pain often emerges...
March 27, 2024: Pain
https://read.qxmd.com/read/38537053/characterizing-the-opioidergic-mechanisms-of-repetitive-transcranial-magnetic-stimulation-induced-analgesia-a-randomized-controlled-trial
#15
JOURNAL ARTICLE
Ying Liu, Junfeng Sun, Chaomin Wu, Jinxuan Ren, Yanni He, Na Sun, Hao Huang, QunShan Chen, Dan Liu, Yangyuxin Huang, Feng Xu, Lina Yu, Bernadette M Fitzgibbon, Robin F H Cash, Paul B Fitzgerald, Min Yan, Xianwei Che
Repetitive transcranial magnetic stimulation (rTMS) is a promising technology to reduce chronic pain. Investigating the mechanisms of rTMS analgesia holds the potential to improve treatment efficacy. Using a double-blind and placebo-controlled design at both stimulation and pharmacologic ends, this study investigated the opioidergic mechanisms of rTMS analgesia by abolishing and recovering analgesia in 2 separate stages across brain regions and TMS doses. A group of 45 healthy participants were equally randomized to the primary motor cortex (M1), the dorsolateral prefrontal cortex (DLPFC), and the Sham group...
March 26, 2024: Pain
https://read.qxmd.com/read/38635483/asymmetrical-atrophy-of-the-paraspinal-muscles-in-patients-undergoing-unilateral-lumbar-medial-branch-radiofrequency-neurotomy
#16
JOURNAL ARTICLE
Ali E Guven, Gisberto Evangelisti, Marco D Burkhard, Paul Köhli, Jan Hambrecht, Jiaqi Zhu, Erika Chiapparelli, Michael Kelly, Koki Tsuchiya, Krizia Amoroso, Arman Zadeh, Jennifer Shue, Ek Tsoon Tan, Andrew A Sama, Federico P Girardi, Frank P Cammisa, Alexander P Hughes
Lumbar medial branch radiofrequency neurotomy (RFN), a common treatment for chronic low back pain due to facet joint osteoarthritis (FJOA), may amplify paraspinal muscle atrophy due to denervation. This study aimed to investigate the asymmetry of paraspinal muscle morphology change in patients undergoing unilateral lumbar medial branch RFN. Data from patients who underwent RFN between March 2016 and October 2021 were retrospectively analyzed. Lumbar foramina stenosis (LFS), FJOA, and fatty infiltration (FI) functional cross-sectional area (fCSA) of the paraspinal muscles were assessed on preinterventional and minimum 2-year postinterventional MRI...
March 22, 2024: Pain
https://read.qxmd.com/read/38537054/the-dynamics-of-pain-avoidance-the-exploration-exploitation-dilemma
#17
JOURNAL ARTICLE
Angelos-Miltiadis Krypotos, Geert Crombez, Johan W S Vlaeyen
No abstract text is available yet for this article.
March 22, 2024: Pain
https://read.qxmd.com/read/38501988/identification-of-group-differences-in-predictive-anticipatory-biasing-of-pain-during-uncertainty-preparing-for-the-worst-but-hoping-for-the-best
#18
JOURNAL ARTICLE
Irina A Strigo, Molly Kadlec, Jennifer M Mitchell, Alan N Simmons
Pain anticipation during conditions of uncertainty can unveil intrinsic biases, and understanding these biases can guide pain treatment interventions. This study used machine learning and functional magnetic resonance imaging to predict anticipatory responses in a pain anticipation experiment. One hundred forty-seven participants that included healthy controls (n = 57) and individuals with current and/or past mental health diagnosis (n = 90) received cues indicating upcoming pain stimuli: 2 cues predicted high and low temperatures, while a third cue introduced uncertainty...
March 15, 2024: Pain
https://read.qxmd.com/read/38501980/effect-of-esketamine-combined-with-pregabalin-on-acute-postsurgical-pain-in-patients-who-underwent-resection-of-spinal-neoplasms-a-randomized-controlled-trial
#19
JOURNAL ARTICLE
Yang Zhou, Wanchen Sun, Yuxuan Fu, Jing Wang, Jingyi Fan, Yuchao Liang, Wenqing Jia, Ruquan Han
Moderate-to-severe acute postsurgical pain (APSP) can prolong the recovery and worsen the prognosis of patients who undergo spinal surgery. Esketamine and pregabalin may resolve APSP without causing hyperpathia or respiratory depression after surgery. However, there are other risks, such as dissociative symptoms. We designed a randomized controlled trial to investigate the effect of the combination of these 2 drugs on the incidence of APSP in patients who underwent resection of spinal neoplasms. Patients aged 18 to 65 years were randomized to receive esketamine (a bolus dose of 0...
March 15, 2024: Pain
https://read.qxmd.com/read/38501985/interoception-and-ad-bud-craig-s-paradigm-shifting-legacy
#20
JOURNAL ARTICLE
Irina A Strigo, David Andrew, Alan N Simmons, Henry C Evrard, Anders Blomqvist, Jonathan O Dostrovsky
No abstract text is available yet for this article.
March 14, 2024: Pain
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