journal
https://read.qxmd.com/read/38528984/relationships-between-the-spinal-dural-pulsations-and-the-short-term-efficacy-of-lumbar-epidural-steroid-injection
#1
JOURNAL ARTICLE
Chan Hong Park, Sang Ho Lee
BACKGROUND: Lumbar spinal stenosis (LSS) causes low back pain, leg pain, numbness in the leg, and neurogenic intermittent claudication. Epidural steroid injection (ESI) has been used for treating spinal stenosis symptoms. We hypothesized that dural pulsation was variable for lumbar spinal stenosis. In cases of the presence of dural pulsation, the pain relief after the ESI was better than in the absence of dural pulsation. This study aimed at investigating the relationships between the presence or absence of spinal dural pulsations and the efficacy of ESI...
2024: Pain Research & Management
https://read.qxmd.com/read/38410126/ngf-signaling-exacerbates-koa-peripheral-hyperalgesia-via-the-increased-trpv1-labeled-synovial-sensory-innervation-in-koa-rats
#2
JOURNAL ARTICLE
Zixiu Liu, Mingchao Li, Li Zhang, Xiaoqing Shi, Taiyang Liao, Lishi Jie, Likai Yu, Peimin Wang
OBJECTIVES: Knee osteoarthritis (KOA) pain is caused by nociceptors, which are actually sensory nerve fiber endings that can detect stimuli to produce and transmit pain signals, and high levels of NGF in synovial tissue led to peripheral hyperalgesia in KOA. The purpose of this study is to investigate how sensory nerve fibers respond to the NGF/TrKA signal pathway and mediate the peripheral hyperalgesia in KOA rats. METHODS: Forty SD male rats were randomly divided into 4 groups: normal, KOA, KOA + NGF, and KOA + siRNA TrKA...
2024: Pain Research & Management
https://read.qxmd.com/read/38327724/neuropathic-pain-medication-and-antidepressant-use-after-disability-pension-in-patients-with-spinal-cord-stimulation-for-persistent-spinal-pain-syndrome
#3
JOURNAL ARTICLE
Hanna Kaijankoski, Mette Nissen, Tiina-Mari Ikäheimo, Mikael von Und Zu Fraunberg, Olavi Airaksinen, Jukka Huttunen
BACKGROUND: Treatment of persistent spinal pain syndrome (PSPS) is challenging. Chronic pain associated with PSPS can lead to an impaired ability to work. OBJECTIVE: To obtain information on whether receiving a disability pension (DP) affects pain and pain treatments in retiring working-age PSPS patients. Neuropathic pain medication and antidepressant use were considered as an indicator of neuropathic pain. METHODS: The study group comprised 129 consecutive PSPS patients with spinal cord stimulation (SCS) devices implanted at Kuopio University Hospital Neurosurgery between January 1, 1996, and December 31, 2014...
2024: Pain Research & Management
https://read.qxmd.com/read/38318481/how-do-we-treat-children-with-anterior-cutaneous-nerve-entrapment-syndrome-and-is-the-biopsychosocial-model-also-being-applied-a-scoping-review
#4
REVIEW
Anke P C Top, Thomas G de Leeuw, Wichor M Bramer, Bernadette C M de Mol, Frank J P M Huygen, Maaike Dirckx
BACKGROUND: Evidence-based guidelines for managing anterior cutaneous nerve entrapment syndrome (ACNES) in children are absent. The primary aim of this review was to scrutinize the evidence supporting currently used treatment interventions. In accordance with the World Health Organization (WHO) guidelines for managing chronic pain in children, these patients and their families and caregivers should be treated within the context of the biopsychosocial model; pain should not be treated purely as a biomedical problem...
2024: Pain Research & Management
https://read.qxmd.com/read/38312327/relationship-between-fear-avoidance-beliefs-and-reaction-time-changes-prior-to-and-following-exercise-induced-muscle-fatigue-in-chronic-low-back-pain
#5
JOURNAL ARTICLE
Wenwu Xiao, Huaichun Yang, Zengming Hao, Menglin Li, Mengchu Zhao, Siyun Zhang, Guifang Zhang, Haian Mao, Chuhuai Wang
BACKGROUND: Reaction time is a reliable indicator of the velocity and efficiency of neuromuscular control and may be associated with fear-avoidance beliefs. However, the effect of exercise-induced muscle fatigue on reaction time in chronic low back pain (cLBP) and its relationship with fear-avoidance beliefs remains poorly understood. OBJECTIVES: This study aimed to reveal the relationship between fear-avoidance beliefs and reaction time changes before and after exercise-induced muscle fatigue in cLBP...
2024: Pain Research & Management
https://read.qxmd.com/read/38274399/a-comparison-of-the-effects-of-acupressure-and-music-on-venipuncture-pain-intensity-in-children-a-randomized-controlled-clinical-trial
#6
RANDOMIZED CONTROLLED TRIAL
Faezeh Daihimfar, Hassan Babamohamadi, Raheb Ghorbani
Pain from injections is common in children of all ages, and more than 90% of hospitalized children experience invasive and painful procedures such as venipuncture. In light of the complications associated with pain relief medications, nonpharmacological and complementary medicine approaches have gained attention. This study aims to compare the effects of acupressure and music on venipuncture pain intensity in children. This randomized controlled clinical trial involved 180 children aged 3-6 years who sought treatment at the Children's Medical Center Hospital Emergency Department at Tehran University of Medical Sciences, Iran...
2024: Pain Research & Management
https://read.qxmd.com/read/38223902/quadratus-lumborum-block-versus-fascia-iliaca-compartment-block-for-acetabular-fracture-surgery-by-stoppa-method-a-double-blind-randomized-noninferiority-trial
#7
RANDOMIZED CONTROLLED TRIAL
Alireza Mirkheshti, Morteza Hashemian, Dariush Abtahi, Sara Shayegh, Alireza Manafi-Rasi, Shahram Sayadi, Elham Memary, Nazli Karami, Baharak Rostamian, Alireza Shakeri
BACKGROUND: Acetabular fracture surgeries are frequently accompanied by protracted and severe perioperative pain, and there is no consensus on optimal pain relief management. AIM: This study aimed at comparing the analgesic efficacy of fascia iliaca compartment block (FICB) and quadratus lumborum block (QLB) in patients with acetabular fractures undergoing surgery using the Stoppa method. METHODS: In this double-blind, randomized, noninferiority clinical trial, adult patients undergoing spinal anesthesia for acetabular fracture surgery, in Imam Hossein Hospital, Tehran, Iran (IRCT20191114045435N1), were randomly divided into two groups: FICB ( n  = 22) and QLB ( n  = 24)...
2024: Pain Research & Management
https://read.qxmd.com/read/38213956/role-of-tnf-%C3%AE-in-the-pathogenesis-of-migraine
#8
REVIEW
Amrit Sudershan, Srishty Sudershan, Isha Sharma, Hardeep Kumar, Rakesh K Panjaliya, Parvinder Kumar
BACKGROUND: Neurogenic neuroinflammation has a wide role in migraine pathogenesis including the transition from episodic migraine to chronic one. The seed molecule of neurogenic neuroinflammation, i.e., the TNF- α proinflammatory molecule, has gathered a lot of attention. This pleiotropic cytokine is a classical component of inflammatory soup, secreted by the microglial cell, and promotes a wide range of inflammatory reactions. AIM: In this review, we aimed to provide a culminating and comprehending glimpse into the TNF- α in association with the migraine...
2024: Pain Research & Management
https://read.qxmd.com/read/38178921/assessment-of-analgesic-efficacy-of-bilateral-lumbar-erector-spinae-plane-block-for-postoperative-pain-following-lumbar-laminectomy-a-single-blind-randomized-clinical-trial
#9
RANDOMIZED CONTROLLED TRIAL
Seyed Amirreza Akhlagh, Arash Farbood, Mahsa Tahvili, Afshin Amini, Keyvan Eghbal, Naeimehossadat Asmarian, Mahsa Banifatemi, Seyed Ali Hosseini
BACKGROUND: The erector spinae plane (ESP) block is a novel approach to minimizing postoperative pain. We investigated the efficacy and side effects of the ultrasonography-guided bilateral ESP block in reducing pain in the first 24 hours after lumbar laminectomy. MATERIALS AND METHODS: We conducted a single-blind (statistical analyst and those responsible for recording patient information postoperation were unaware of the study groups) randomized clinical trial on 50 patients aged 18 to 65 with American Society of Anesthesiology (ASA) class I or II physical status scheduled for lumbar laminectomy surgery at Shahid Chamran Hospital, Shiraz, Iran...
2023: Pain Research & Management
https://read.qxmd.com/read/38149075/perioperative-nerve-blockade-reduces-acute-postoperative-pain-after-orthognathic-surgery
#10
JOURNAL ARTICLE
Yuka Oono, Saori Takagi, Lars Arendt-Nielsen, Hikaru Kohase
BACKGROUND: The role of perioperative pain management is not only to reduce acute postoperative pain (POP) but also to prevent chronic POP. It would be important to know the usefulness of nerve blockade for perioperative management. However, it has not been extensively studied in orofacial surgery. The objective of the study was to investigate whether perioperative nerve blockade reduces acute POP after orthognathic surgery. METHODS: Patients scheduled for orthognathic surgery were retrospectively reviewed ("preblock group": the nerve blockade was performed before emergence from general anesthesia, and "no preblock group": the nerve blockade was not performed before emergence from general anesthesia)...
2023: Pain Research & Management
https://read.qxmd.com/read/38144227/coping-strategies-with-genito-pelvic-pain-penetration-disorder-a-qualitative-study
#11
JOURNAL ARTICLE
Mojdeh Banaei, Vahid Mehrnoush, Nasibeh Roozbeh, Nourossadat Kariman
BACKGROUND: Genital/pelvic pain penetration disorder (GPPPD) decreased mental and physical functioning, reduced quality of life, and reduced feelings of inadequacy and worthlessness, all of which impair the ability of women with GPPPD to enjoy sex. This qualitative study was conducted to identify which factors can reduce sexual stress and help Iranian women cope with GPPPD. METHODS: This qualitative study was conducted through the participation of 18 women with GPPPD diagnosed by a sexologist and using DSM-IV diagnostic criteria from March to July 2022, Iran...
2023: Pain Research & Management
https://read.qxmd.com/read/38047157/orientin-reduces-the-effects-of-repeated-procedural-neonatal-pain-in-adulthood-network-pharmacology-analysis-molecular-docking-analysis-and-experimental-validation
#12
JOURNAL ARTICLE
Dong-Dong Guo, Hai-Yan Huang, Hai-E Liu, Kun Liu, Xing-Jing Luo
BACKGROUND: Premature infants often undergo painful procedures and consequently experience repeated procedural neonatal pain. This can elicit hyperalgesia and cognitive impairment in adulthood. Treatments for neonatal pain are limited. Orientin is a flavonoid C-glycoside that has repeatedly been shown to have pharmacological effects in the past decades. The aim of this study was to systematically explore the effect of orientin on repeated procedural neonatal pain using network pharmacology, molecular docking analysis, and experimental validation...
2023: Pain Research & Management
https://read.qxmd.com/read/38033371/the-impact-and-correlation-of-anxiety-and-depression-on-pressure-pain-threshold-of-acupoints-in-patients-with-chronic-pelvic-inflammatory-disease
#13
JOURNAL ARTICLE
Chenxi Liao, Yu Tan, Kai Wang, Xin Wen, Xiang Hu, Yefang Huang, Ying Li
BACKGROUND: Chronic pelvic inflammatory disease (CPID) is a clinically common gynecological disease. Patients experience chronic pelvic pain and often accompany with emotional dysfunction. However, the impact and correlation of anxiety and depression on pain sensitization is not completely known. OBJECTIVE: To explore the differences and correlations among anxiety, depression, and pressure pain threshold (PPT) of acupoints in patients with CPID. METHODS: One hundred and forty-seven patients with CPID were recruited...
2023: Pain Research & Management
https://read.qxmd.com/read/38023826/glial-cells-of-the-central-nervous-system-a-potential-target-in-chronic-prostatitis-chronic-pelvic-pain-syndrome
#14
REVIEW
Yongfeng Lao, Zewen Li, Yanan Bai, Weijia Li, Jian Wang, Yanan Wang, Qingchao Li, Zhilong Dong
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is one of the most common diseases of the male urological system while the etiology and treatment of CP/CPPS remain a thorny issue. Cumulative research suggested a potentially important role of glial cells in CP/CPPS. This narrative review retrospected literature and grasped the research process about glial cells and CP/CPPS. Three types of glial cells showed a crucial connection with general pain and psychosocial symptoms. Microglia might also be involved in lower urinary tract symptoms...
2023: Pain Research & Management
https://read.qxmd.com/read/38023825/can-ultrasound-guided-continuous-paravertebral-block-reduce-the-incidence-of-chronic-postsurgical-pain-in-patients-with-thoracoscopic-lung-cancer-surgery-a-randomized-controlled-trial
#15
RANDOMIZED CONTROLLED TRIAL
Wei Ran, Huan Luo, Zhiqiao Wang, Yonggang Hao, Ning Liang, Ping Li, Xia Yin, Jin Gao
BACKGROUND: Thoracoscopic lung cancer surgery is accompanied by severe pain. Both continuous paravertebral block (CPVB) and continuous wound infiltration (CWI) are widely used for perioperative analgesia in thoracoscopic surgery. However, the effects of these different methods on chronic postsurgical pain (CPSP) are still unknown. Patients and Methods . This prospective randomized controlled trial assessed the eligibility of 113 patients. Ninety-seven patients who met the inclusion criteria were randomly divided into a CPVB group and a CWI group, and 80 patients were analyzed in the final study...
2023: Pain Research & Management
https://read.qxmd.com/read/37953807/investigation-for-factors-affecting-body-perception-disturbance-in-patients-with-low-back-pain-by-mechanism-based-classification-of-pain-a-cross-sectional-study
#16
JOURNAL ARTICLE
Yoshito Kurashima, Takumi Nakamura, Taishi Mukaiyama, Kenji Hasegawa, Hironobu Kuruma
BACKGROUND: Central sensitization is a pathophysiological cause of chronic low back pain and is linked with psychosocial factors. The association between central sensitization (CS) and body perception disturbance is currently unclear, and no prior studies have investigated this relationship in patients with acute or subacute low back pain. The objective of this study was to investigate potential factors that influence body perception disturbance using a mechanistic classification of low back pain...
2023: Pain Research & Management
https://read.qxmd.com/read/37869446/does-a-positive-response-to-transforaminal-epidural-steroid-injection-identify-patients-who-can-avoid-surgery-for-two-years
#17
JOURNAL ARTICLE
Aki Fujiwara, Keisuke Watanabe, Hideki Shigematsu, Katsuhiro Kimoto, Mitsuru Ida, Yasuhito Tanaka, Masahiko Kawaguchi
BACKGROUND: Transforaminal epidural steroid injection (TFESI) is widely used to manage lumbar radiculopathy. In clinical settings, patients often undergo repeated transforaminal epidural injections with or without steroid administration. OBJECTIVES: To examine whether a positive response to TFESI at the first month, can in clinical settings, identify patients with radiculopathy who can avoid surgery for two years. Study Design/Setting . This prospective observational study was conducted at an academic medical center...
2023: Pain Research & Management
https://read.qxmd.com/read/37780096/racial-ethnic-and-language-based-inequities-in-inpatient-opioid-prescribing-by-diagnosis-from-internal-medicine-services-a-retrospective-cohort-study
#18
JOURNAL ARTICLE
Mihir Joshi, Priya A Prasad, Colin C Hubbard, Nicholas Iverson, Solmaz P Manuel, Margaret C Fang, Aksharananda Rambachan
INTRODUCTION: Opioid administration is extremely common in the inpatient setting, yet we do not know how the administration of opioids varies across different medical conditions and patient characteristics on internal medicine services. Our goal was to assess racial, ethnic, and language-based inequities in opioid prescribing practices for patients admitted to internal medicine services. METHODS: We conducted a retrospective cohort study of all adult patients admitted to internal medicine services from 2013 to 2021 and identified subcohorts of patients treated for the six most frequent primary hospital conditions (pneumonia, sepsis, cellulitis, gastrointestinal bleed, pyelonephritis/urinary tract infection, and respiratory disease) and three select conditions typically associated with pain (abdominal pain, acute back pain, and pancreatitis)...
2023: Pain Research & Management
https://read.qxmd.com/read/37719895/clinical-application-of-inferior-alveolar-nerve-block-device-for-safe-and-secure-ianb-by-any-operator
#19
JOURNAL ARTICLE
Tomoyasu Noguchi, Kento Odaka, Ken-Ichi Fukuda
The inferior alveolar nerve block (IANB) is an established technique with a success rate of 60-80%; however, large errors have been reported among operators. Some dentists do not prefer to use IANB because of the risk of complications. Nevertheless, it is a useful technique for pain control, and a secure IANB offers significant benefits to operators and patients. This case series study aimed to investigate the efficacy of the "IANB Device," a nerve block guide for IANB, and the adverse events associated with its use in clinical practice...
2023: Pain Research & Management
https://read.qxmd.com/read/37719894/the-relationship-between-pain-catastrophizing-and-cognitive-function-in-chronic-musculoskeletal-pain-a-scoping-review
#20
REVIEW
Cory Alcon, Elizabeth Bergman, John Humphrey, Rupal M Patel, Sharon Wang-Price
OBJECTIVE: Chronic musculoskeletal pain (CMP) poses a considerable threat to physical, mental, and financial health worldwide. Beyond physical difficulties, CMP has a pronounced impact on pain behaviors and cognitive function. The purpose of this scoping review was to examine the relationship between pain catastrophizing (PC) and cognitive function in CMP, identify gaps in the literature, and provide future directions for research on the topic. METHODS: Search strings were entered in the following databases: PubMed, CINAHL, Nursing and Allied Health, Ovid Emcare, PsycInfo, and Scopus...
2023: Pain Research & Management
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