journal
https://read.qxmd.com/read/38099731/admission-functional-status-is-associated-with-intensivists-perception-of-extracorporeal-membrane-oxygenation-candidacy-for-pediatric-acute-respiratory-failure
#21
JOURNAL ARTICLE
Brenna C McCabe, Wynne E Morrison, Ryan W Morgan, Adam S Himebauch
OBJECTIVES: To determine the association between admission Functional Status Scale (FSS) category and perceived extracorporeal membrane oxygenation (ECMO) candidacy for pediatric acute respiratory failure. DESIGN: Prospective, cross-sectional study. SETTING: Single-center, quaternary, and ECMO referral academic children's hospital between March 2021 and January 2022. SUBJECTS: Pediatric intensivists directly caring for patients admitted with acute respiratory failure secondary to shock or respiratory disease...
December 15, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38088772/spiritual-care-in-picus-a-u-s-survey-of-245-training-fellows-2020-2021
#22
JOURNAL ARTICLE
Paige E Stevens, Caroline E Rassbach, FeiFei Qin, Kevin W Kuo
OBJECTIVES: To understand the perspectives of pediatric fellows training in critical care subspecialties about providing spiritual care. DESIGN: Cross-sectional survey of United States National Residency Matching Program pediatric fellows training in critical care specialties. SETTING: Online survey open from April to May 2021. SUBJECTS: A total of 720 fellows (165 cardiology, 259 critical care, and 296 neonatology) were contacted, with a response rate of 245 of 720 (34%)...
December 13, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38088770/child-opportunity-index-and-pediatric-intensive-care-outcomes-a-multicenter-retrospective-study-in-the-united-states
#23
JOURNAL ARTICLE
Michael C McCrory, Manzilat Akande, Katherine N Slain, Curtis E Kennedy, Meredith C Winter, Morgan G Stottlemyre, Martin K Wakeham, Kyle A Barnack, Jia Xin Huang, Meesha Sharma, Adrian D Zurca, Neethi P Pinto, Adam C Dziorny, Aline B Maddux, Anjali Garg, Alan G Woodruff, Mary E Hartman, Otwell D Timmons, R Scott Heidersbach, Michael J Cisco, Anthony A Sochet, Brian J Wells, Elizabeth E Halvorson, Amit K Saha
OBJECTIVES: To evaluate for associations between a child's neighborhood, as categorized by Child Opportunity Index (COI 2.0), and 1) PICU mortality, 2) severity of illness at PICU admission, and 3) PICU length of stay (LOS). DESIGN: Retrospective cohort study. SETTING: Fifteen PICUs in the United States. PATIENTS: Children younger than 18 years admitted from 2019 to 2020, excluding those after cardiac procedures. Nationally-normed COI category (very low, low, moderate, high, very high) was determined for each admission by census tract, and clinical features were obtained from the Virtual Pediatric Systems LLC (Los Angeles, CA) data from each site...
December 13, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38088768/neonatal-chylothorax-and-early-fluid-overload-after-cardiac-surgery-retrospective-analysis-of-the-neonatal-and-pediatric-heart-and-renal-outcomes-network-registry-2015-2018
#24
JOURNAL ARTICLE
Katie Brandewie, Jeffrey Alten, Melissa Winder, Kenneth Mah, Kathryn Holmes, Garrett Reichle, Andrew Smith, Huaiyu Zang, David Bailly
OBJECTIVES: To evaluate the association between postoperative cumulative fluid balance (FB) and development of chylothorax in neonates after cardiac surgery. DESIGN: Multicenter, retrospective cohort identified within the Neonatal and Pediatric Heart and Renal Outcomes Network (NEPHRON) Registry. SETTING: Twenty-two hospitals were involved with NEPHRON, from September 2015 to January 2018. PATIENTS: Neonates (< 30 d old) undergoing index cardiac operation with or without cardiopulmonary bypass (CPB) entered into the NEPHRON Registry...
December 13, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38088765/early-cardiac-arrest-hemodynamics-end-tidal-co2-and-outcome-in-pediatric-extracorporeal-cardiopulmonary-resuscitation-secondary-analysis-of-the-icu-resuscitation-project-dataset-2016-2021
#25
JOURNAL ARTICLE
Andrew R Yates, Maryam Y Naim, Ron W Reeder, Tageldin Ahmed, Russell K Banks, Michael J Bell, Robert A Berg, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A Carcillo, Todd C Carpenter, J Michael Dean, J Wesley Diddle, Myke Federman, Richard Fernandez, Ericka L Fink, Deborah Franzon, Aisha H Frazier, Stuart H Friess, Kathryn Graham, Mark Hall, David A Hehir, Christopher M Horvat, Leanna L Huard, Tensing Maa, Arushi Manga, Patrick S McQuillen, Ryan W Morgan, Peter M Mourani, Vinay M Nadkarni, Daniel Notterman, Murray M Pollack, Anil Sapru, Carleen Schneiter, Matthew P Sharron, Neeraj Srivastava, Bradley Tilford, Shirley Viteri, David Wessel, Heather A Wolfe, Justin Yeh, Athena F Zuppa, Robert M Sutton, Kathleen L Meert
OBJECTIVES: Cannulation for extracorporeal membrane oxygenation during active extracorporeal cardiopulmonary resuscitation (ECPR) is a method to rescue patients refractory to standard resuscitation. We hypothesized that early arrest hemodynamics and end-tidal Co2 (ETco2) are associated with survival to hospital discharge with favorable neurologic outcome in pediatric ECPR patients. DESIGN: Preplanned, secondary analysis of pediatric Utstein, hemodynamic, and ventilatory data in ECPR patients collected during the 2016-2021 Improving Outcomes from Pediatric Cardiac Arrest study; the ICU-RESUScitation Project (ICU-RESUS; NCT02837497)...
December 13, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38088764/neurological-outcomes-and-quality-of-life-in-children-after-extracorporeal-membrane-oxygenation
#26
JOURNAL ARTICLE
Alizée Michel, Meryl Vedrenne-Cloquet, Manoëlle Kossorotoff, Michaël Thy, Raphaël Levy, Marie Pouletty, Charles De Marcellus, Marion Grimaud, Florence Moulin, Marie Hully, Hina Simonnet, Isabelle Desguerre, Sylvain Renolleau, Mehdi Oualha, Judith Chareyre
RATIONALE: Use of life support with extracorporeal membrane oxygenation (ECMO) is associated with brain injury. However, the consequences of these injuries on subsequent neurologic development and health-related quality of life (HRQoL) are poorly described in children. OBJECTIVES: The aim of this preliminary study was to describe short- and long-term neurologic outcomes in survivors of ECMO, as well as their HRQoL. DESIGN: Retrospective identified cohort with contemporary evaluations...
December 13, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38088760/new-functional-impairment-after-hospital-discharge-by-traumatic-brain-injury-mechanism-in-younger-than-3-years-old-admitted-to-the-picu-in-a-single-center-retrospective-study
#27
JOURNAL ARTICLE
Caitlin R McNamara, Anne Kalinowski, Christopher M Horvat, Barbara A Gaines, Ward M Richardson, Dennis W Simon, Patrick M Kochanek, Rachel P Berger, Ericka L Fink
OBJECTIVES: Children who suffer traumatic brain injury (TBI) are at high risk of morbidity and mortality. We hypothesized that in patients with TBI, the abusive head trauma (AHT) mechanism vs. accidental TBI (aTBI) would be associated with higher frequency of new functional impairment between baseline and later follow-up. DESIGN: Retrospective single center cohort study. SETTING AND PATIENTS: Children younger than 3 years old admitted with TBI to the PICU at a level 1 trauma center between 2014 and 2019...
December 13, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38085024/harnessing-the-promise-of-the-cold-stress-response-for-acute-brain-injury-and-critical-illness-in-infants-and-children
#28
JOURNAL ARTICLE
Travis C Jackson, Jeremy R Herrmann, Ericka L Fink, Alicia K Au, Patrick M Kochanek
No abstract text is available yet for this article.
December 12, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38059739/sedation-research-in-critically-ill-pediatric-patients-proposals-for-future-study-design-from-the-sedation-consortium-on-endpoints-and-procedures-for-treatment-education-and-research-iv-workshop
#29
JOURNAL ARTICLE
Shawn S Jackson, Jennifer J Lee, William M Jackson, Jerri C Price, Sue R Beers, John W Berkenbosch, Katherine V Biagas, Robert H Dworkin, Constance S Houck, Guohua Li, Heidi A B Smith, Denham S Ward, Kanecia O Zimmerman, Martha A Q Curley, Christopher M Horvat, David T Huang, Neethi P Pinto, Cynthia F Salorio, Rebeccah Slater, Beth S Slomine, Leanne L West, David Wypij, Keith O Yeates, Lena S Sun
OBJECTIVES: Sedation and analgesia for infants and children requiring mechanical ventilation in the PICU is uniquely challenging due to the wide spectrum of ages, developmental stages, and pathophysiological processes encountered. Studies evaluating the safety and efficacy of sedative and analgesic management in pediatric patients have used heterogeneous methodologies. The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research (SCEPTER) IV hosted a series of multidisciplinary meetings to establish consensus statements for future clinical study design and implementation as a guide for investigators studying PICU sedation and analgesia...
December 7, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38059735/evaluating-airway-management-in-patients-with-trisomy-21-in-the-picu-and-cardiac-icu-a-retrospective-cohort-study
#30
JOURNAL ARTICLE
Eric J Wilsterman, Marianne E Nellis, Josep Panisello, Awni Al-Subu, Ryan Breuer, Dai Kimura, Conrad Krawiec, Palen P Mallory, Sholeen Nett, Erin Owen, Simon J Parsons, Ronald C Sanders, Annery Garcia-Marcinkiewicz, Natalie Napolitano, Justine Shults, Vinay Nadkarni, Akira Nishisaki
OBJECTIVES: Children with trisomy 21 often have anatomic and physiologic features that may complicate tracheal intubation (TI). TI in critically ill children with trisomy 21 is not well described. We hypothesize that in children with trisomy 21, TI is associated with greater odds of adverse airway outcomes (AAOs), including TI-associated events (TIAEs), and peri-intubation hypoxemia (defined as > 20% decrease in pulse oximetry saturation [Spo2]). DESIGN: Retrospective database study using the National Emergency Airway Registry for Children (NEAR4KIDS)...
December 7, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38059732/the-pediatric-data-science-and-analytics-subgroup-of-the-pediatric-acute-lung-injury-and-sepsis-investigators-network-use-of-supervised-machine-learning-applications-in-pediatric-critical-care-medicine-research
#31
JOURNAL ARTICLE
Julia A Heneghan, Sarah B Walker, Andrea Fawcett, Tellen D Bennett, Adam C Dziorny, L Nelson Sanchez-Pinto, Reid W D Farris, Meredith C Winter, Colleen Badke, Blake Martin, Stephanie R Brown, Michael C McCrory, Manette Ness-Cochinwala, Colin Rogerson, Orkun Baloglu, Ilana Harwayne-Gidansky, Matthew R Hudkins, Rishikesan Kamaleswaran, Sandeep Gangadharan, Sandeep Tripathi, Eneida A Mendonca, Barry P Markovitz, Anoop Mayampurath, Michael C Spaeder
OBJECTIVE: Perform a scoping review of supervised machine learning in pediatric critical care to identify published applications, methodologies, and implementation frequency to inform best practices for the development, validation, and reporting of predictive models in pediatric critical care. DESIGN: Scoping review and expert opinion. SETTING: We queried CINAHL Plus with Full Text (EBSCO), Cochrane Library (Wiley), Embase (Elsevier), Ovid Medline, and PubMed for articles published between 2000 and 2022 related to machine learning concepts and pediatric critical illness...
December 7, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240545/online-abstract-translations
#32
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240544/the-authors-reply
#33
JOURNAL ARTICLE
Erwin Ista, Chani Traube, Marjorie de Neef, Jan Schieveld, Hennie Knoester, Marja Molag, Sapna R Kudchadkar, Jacqueline Strik
No abstract text is available yet for this article.
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240543/about-factors-associated-with-delirium-in-children-a-systematic-review-and-meta-analysis
#34
LETTER
Tao Huang, Yang Liu, Min Tang
No abstract text is available yet for this article.
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240541/advanced-practice-provider-tracheal-intubation-in-pediatric-critical-care-scarcity-and-market-forces
#35
JOURNAL ARTICLE
Jamie McElrath Schwartz, Amanda Betine Levin, Lauren D Booth, Donald H Shaffner
No abstract text is available yet for this article.
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240540/family-challenges-and-navigator-support-it-is-time-we-support-our-families-better
#36
JOURNAL ARTICLE
Lauren Rissman, Erin Talati Paquette
No abstract text is available yet for this article.
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240539/moving-away-from-randomized-controlled-trials-to-hybrid-implementation-studies-for-complex-interventions-in-the-picu
#37
EDITORIAL
Erwin Ista, Monique van Dijk
No abstract text is available yet for this article.
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240538/serum-levels-of-vitamin-c-and-thiamin-in-children-with-suspected-sepsis-a-prospective-observational-cohort-study
#38
JOURNAL ARTICLE
Brett McWhinney, Jacobus Ungerer, Renate LeMarsey, Natalie Phillips, Sainath Raman, Kristen Gibbons, Luregn J Schlapbach
OBJECTIVES: Vitamin C and thiamin have been trialed as adjunctive therapies in adults with septic shock but their role in critically ill children is unclear. We assessed serum levels of vitamin C and thiamin in children evaluated for sepsis. DESIGN: Single-center prospective observational study. Serum levels of vitamin C and thiamin were measured on admission and association with multiple organ dysfunction syndrome (MODS) was explored using logistic regression. SETTING: Emergency department and PICU in a tertiary children's hospital, Queensland, Australia...
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240537/resuscitation-with-vitamin-c-hydrocortisone-and-thiamin-in-children-with-septic-shock-a-multicenter-randomized-pilot-study
#39
RANDOMIZED CONTROLLED TRIAL
Luregn J Schlapbach, Sainath Raman, David Buckley, Shane George, Megan King, Roberta Ridolfi, Amanda Harley, Michele Cree, Debbie Long, Simon Erickson, Puneet Singh, Marino Festa, Kristen Gibbons, Rinaldo Bellomo
OBJECTIVES: Adjunctive therapy with vitamin C, hydrocortisone, and thiamin has been evaluated in adults, but randomized controlled trial (RCT) data in children are lacking. We aimed to test the feasibility of vitamin C, hydrocortisone, and thiamin in PICU patients with septic shock; and to explore whether the intervention is associated with increased survival free of organ dysfunction. DESIGN: Open-label parallel, pilot RCT multicenter study. The primary endpoint was feasibility...
February 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38240536/stress-ulcer-prophylaxis-versus-placebo-a-blinded-pilot-randomized-controlled-trial-to-evaluate-the-safety-of-two-strategies-in-critically-ill-infants-with-congenital-heart-disease
#40
RANDOMIZED CONTROLLED TRIAL
Kimberly I Mills, Ben D Albert, Lori J Bechard, Stephen Chu, Christopher P Duggan, Aditya Kaza, Seth Rakoff-Nahoum, Lynn A Sleeper, Jane W Newburger, Gregory P Priebe, Nilesh M Mehta
OBJECTIVES: The routine use of stress ulcer prophylaxis (SUP) in infants with congenital heart disease (CHD) in the cardiac ICU (CICU) is controversial. We aimed to conduct a pilot study to explore the feasibility of performing a subsequent larger trial to assess the safety and efficacy of withholding SUP in this population (NCT03667703). DESIGN, SETTING, PATIENTS: Single-center, prospective, double-blinded, parallel group (SUP vs. placebo), pilot randomized controlled pilot trial (RCT) in infants with CHD admitted to the CICU and anticipated to require respiratory support for greater than 24 hours...
February 1, 2024: Pediatric Critical Care Medicine
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