Selen Yaman, Meryem Ceyhan, Necati Hancerliogullari, Esin Merve Koc, Tuba Candar, Aytekin Tokmak
OBJECTIVES: Kynurinine (KYN) and its metabolites, which are released during the metabolism of tryptophan, an essential amino acid, have many important functions, such as cellular energy production, regulation of vascular tone, and regulation of the immune system. In this study, we aimed to detect serum KYN levels, which may be an indicator of KYN pathway activity, in idiopathic fetal growth restriction (FGR) and oligohydramnios cases whose pathophysiology is known to be affected by multiple factors, such as placental hypoperfusion, immune dysregulation, and maternal nutrition disorder, and to investigate their relationship with these common obstetric complications...
January 2, 2023: Journal of Perinatal Medicine