M J C Formica, M Fuller-Tyszkiewicz, U Reininghaus, M Kempton, P Delespaul, L de Haan, B Nelson, A Mikocka-Walus, L Olive, S Ruhrmann, B Rutten, A Riecher-Rössler, G Sachs, L Valmaggia, M van der Gaag, P McGuire, J van Os, J A Hartmann
BACKGROUND: Pre-diagnostic stages of psychotic illnesses, including 'clinical high risk' (CHR), are marked by sleep disturbances. These sleep disturbances appear to represent a key aspect in the etiology and maintenance of psychotic disorders. We aimed to examine the relationship between self-reported sleep dysfunction and attenuated psychotic symptoms (APS) on a day-to-day basis. METHODS: Seventy-six CHR young people completed the Experience Sampling Methodology (ESM) component of the European Union Gene-Environment Interaction Study, collected through PsyMate® devices, prompting sleep and symptom questionnaires 10 times daily for 6 days...
March 7, 2024: Psychological Medicine