journal
https://read.qxmd.com/read/37217205/the-causal-role-of-c-reactive-protein-and-interleukin-6-on-anxiety-and-depression-symptoms-and-life-satisfaction-mendelian-randomisation-analyses-in-the-hunt-study
#21
JOURNAL ARTICLE
Ole-Jørgen Bekkevold, Jan Kristian Damås, Ben Michael Brumpton, Bjørn Olav Åsvold
BACKGROUND: Serum levels of C-reactive protein (CRP) and interleukin-6 (IL-6) have been associated with anxiety and depression in cross-sectional and Mendelian randomisation studies, but results regarding the effect size and direction have been mixed. A recent Mendelian Randomisation (MR) study suggested that CRP may decrease and IL-6 may increase anxiety and depression symptoms. METHODS: Among 68 769 participants of the population-based Trøndelag Health Study (HUNT), we performed cross-sectional observational and one-sample MR analyses of serum CRP and two-sample MR analysis of serum IL-6...
May 23, 2023: Psychological Medicine
https://read.qxmd.com/read/37212052/prediction-of-estimated-risk-for-bipolar-disorder-using-machine-learning-and-structural-mri-features
#22
JOURNAL ARTICLE
Pavol Mikolas, Michael Marxen, Philipp Riedel, Kyra Bröckel, Julia Martini, Fabian Huth, Christina Berndt, Christoph Vogelbacher, Andreas Jansen, Tilo Kircher, Irina Falkenberg, Martin Lambert, Vivien Kraft, Gregor Leicht, Christoph Mulert, Andreas J Fallgatter, Thomas Ethofer, Anne Rau, Karolina Leopold, Andreas Bechdolf, Andreas Reif, Silke Matura, Felix Bermpohl, Jana Fiebig, Thomas Stamm, Christoph U Correll, Georg Juckel, Vera Flasbeck, Philipp Ritter, Michael Bauer, Andrea Pfennig
BACKGROUND: Individuals with bipolar disorder are commonly correctly diagnosed a decade after symptom onset. Machine learning techniques may aid in early recognition and reduce the disease burden. As both individuals at risk and those with a manifest disease display structural brain markers, structural magnetic resonance imaging may provide relevant classification features. METHODS: Following a pre-registered protocol, we trained linear support vector machine (SVM) to classify individuals according to their estimated risk for bipolar disorder using regional cortical thickness of help-seeking individuals from seven study sites ( N = 276)...
May 22, 2023: Psychological Medicine
https://read.qxmd.com/read/37212050/how-do-aspects-of-selfhood-relate-to-depression-and-anxiety-among-youth-a-meta-analysis
#23
REVIEW
GeckHong Yeo, Cameron Tan, Dean Ho, Roy F Baumeister
Adolescents' sense of self has important implications for their mental health. Despite more than two decades of work, scholars have yet to amass evidence across studies to elucidate the role of selfhood in the mental health of adolescents. Underpinned by the conceptual model of selfhood, this meta-analytic review investigated the strength of associations of different facets of selfhood and their associated traits with depression and anxiety, moderating factors that attenuate or exacerbate these associations, and their causal influences...
May 22, 2023: Psychological Medicine
https://read.qxmd.com/read/37211861/psychiatry-in-the-service-of-repression
#24
JOURNAL ARTICLE
Amir Kabir
No abstract text is available yet for this article.
May 22, 2023: Psychological Medicine
https://read.qxmd.com/read/37203460/cultural-contributions-to-adults-self-rated-mental-health-problems-and-strengths-7-culture-clusters-28-societies-16-906-adults
#25
JOURNAL ARTICLE
William E Copeland, Masha Y Ivanova, Thomas M Achenbach, Lori V Turner, Guangyu Tong, Adelina Ahmeti-Pronaj, Alma Au, Monica Bellina, J Carlos Caldas, Yi-Chuen Chen, Ladislav Csemy, Marina M da Rocha, Anca Dobrean, Lourdes Ezpeleta, Yasuko Funabiki, Valerie S Harder, Felipe Lecannelier, Marie Leiner de la Cabada, Patrick Leung, Jianghong Liu, Safia Mahr, Sergey Malykh, Jasminka Markovic, David M Ndetei, Kyung Ja Oh, Jean-Michel Petot, Geylan Riad, Direnc Sakarya, Virginia C Samaniego, Sandra Sebre, Mimoza Shahini, Edwiges Silvares, Roma Simulioniene, Elvisa Sokoli, Joel B Talcott, Natalia Vazquez, Tomasz Wolanczyk, Ewa Zasepa
BACKGROUND: It is unknown how much variation in adult mental health problems is associated with differences between societal/cultural groups, over and above differences between individuals. METHODS: To test these relative contributions, a consortium of indigenous researchers collected Adult Self-Report (ASR) ratings from 16 906 18- to 59-year-olds in 28 societies that represented seven culture clusters identified in the Global Leadership and Organizational Behavioral Effectiveness study (e...
May 19, 2023: Psychological Medicine
https://read.qxmd.com/read/37203450/a-longitudinal-study-of-childhood-maltreatment-subcortical-development-and-subcortico-cortical-structural-maturational-coupling-from-early-to-late-adolescence
#26
JOURNAL ARTICLE
Divyangana Rakesh, Reham Elzeiny, Nandita Vijayakumar, Sarah Whittle
BACKGROUND: Examining neurobiological mechanisms that may transmit the effects of childhood maltreatment on mental health in youth is crucial for understanding vulnerability to psychopathology. This study investigated associations between childhood maltreatment, adolescent structural brain development, and mental health trajectories into young-adulthood. METHODS: Structural magnetic resonance imaging data was acquired from 144 youth at three time points (age 12, 16, and 18 years)...
May 19, 2023: Psychological Medicine
https://read.qxmd.com/read/37203448/the-co-occurrence-of-manic-and-depressive-dimensions-in-early-psychosis-a-latent-transition-analysis
#27
JOURNAL ARTICLE
Julie Ramain, Lilith Abrahamyan Empson, Luis Alameda, Alessandra Solida, Julien Elowe, Nadir Mebdouhi, Philippe Conus, Philippe Golay
BACKGROUND: Frequently associated with early psychosis, depressive and manic dimensions may play an important role in its course and outcome. While manic and depressive symptoms can alternate and co-occur, most of the studies in early intervention investigated these symptoms independently. The aim of this study was therefore to explore the co-occurrence of manic and depressive dimensions, their evolution and impact on outcomes. METHODS: We prospectively studied first-episode psychosis patients ( N = 313) within an early intervention program over 3 years...
May 19, 2023: Psychological Medicine
https://read.qxmd.com/read/37203447/which-psychotherapy-is-most-effective-and-acceptable-in-the-treatment-of-adults-with-a-sub-clinical-borderline-personality-disorder-a-systematic-review-and-network-meta-analysis
#28
REVIEW
Kim Setkowski, Christina Palantza, Wouter van Ballegooijen, Renske Gilissen, Matthijs Oud, Ioana A Cristea, Hisashi Noma, Toshi A Furukawa, Arnoud Arntz, Anton J L M van Balkom, Pim Cuijpers
A broad range of psychotherapies have been proposed and evaluated in the treatment of borderline personality disorder (BPD), but the question which specific type of psychotherapy is most effective remains unanswered. In this study, two network meta-analyses (NMAs) were conducted investigating the comparative effectiveness of psychotherapies on (1) BPD severity and (2) suicidal behaviour (combined rate). Study drop-out was included as a secondary outcome. Six databases were searched until 21 January 2022, including RCTs on the efficacy of any psychotherapy in adults (⩾18 years) with a diagnosis of (sub)clinical BPD...
May 19, 2023: Psychological Medicine
https://read.qxmd.com/read/37203444/examining-associations-between-genetic-and-neural-risk-for-externalizing-behaviors-in-adolescence-and-early-adulthood
#29
JOURNAL ARTICLE
Sarah J Brislin, Jessica E Salvatore, Jacquelyn M Meyers, Chella Kamarajan, Martin H Plawecki, Howard J Edenberg, Samuel Kuperman, Jay Tischfield, Victor Hesselbrock, Andrey P Anokhin, David B Chorlian, Marc A Schuckit, John I Nurnberger, Lance Bauer, Gayathri Pandey, Ashwini K Pandey, John R Kramer, Grace Chan, Bernice Porjesz, Danielle M Dick
BACKGROUND: Researchers have identified genetic and neural risk factors for externalizing behaviors. However, it has not yet been determined if genetic liability is conferred in part through associations with more proximal neurophysiological risk markers. METHODS: Participants from the Collaborative Study on the Genetics of Alcoholism, a large, family-based study of alcohol use disorders were genotyped and polygenic scores for externalizing (EXT PGS) were calculated...
May 19, 2023: Psychological Medicine
https://read.qxmd.com/read/37198936/longitudinal-course-of-endocannabinoids-and-n-acylethanolamines-in-hair-of-mothers-and-their-children-in-the-first-year-postpartum-investigating-the-relevance-of-maternal-childhood-maltreatment-experiences
#30
JOURNAL ARTICLE
Melissa Hitzler, Lynn Matits, Anja M Gumpp, Alexandra M Bach, Ute Ziegenhain, Wei Gao, Iris-Tatjana Kolassa, Alexander Behnke
BACKGROUND: Childhood maltreatment (CM) exerts long-lasting psychological and biological alterations in affected individuals and might also affect the endocannabinoid (eCB) system which modulates inflammation and the endocrine stress response. Here, we investigated the eCB system of women with and without CM and their infants using hair samples representing eCB levels accumulated during the last trimester of pregnancy and 10-12 months postpartum. METHODS: CM exposure was assessed with the Childhood Trauma Questionnaire ...
May 18, 2023: Psychological Medicine
https://read.qxmd.com/read/37194497/blunted-neurobiological-reactivity-and-attentional-bias-to-threat-underlie-stress-related-disorders-in-women-survivors-of-intimate-partner-violence
#31
JOURNAL ARTICLE
X Goldberg, C Espelt, R Nadal, Y Alon, D Palao, Y Bar-Haim, A Armario
BACKGROUND: Intimate partner violence (IPV) alters women's neurobiological stress response systems. We propose that individual differences early in the attentional processing of threats are associated with these neurobiological mechanisms and contribute to mental illness in this population. METHODS: We assessed attentional bias in relation to threat (AB) in women survivors of IPV ( n = 69) and controls ( n = 36), and examined overall cortisol secretion using hair cortisol (HC), and stress responsiveness measuring salivary cortisol and α -amylase (sAA) before (T0), and after (T1, T2) an acute psychosocial stress task (Trier Social Stress Test)...
May 17, 2023: Psychological Medicine
https://read.qxmd.com/read/37194490/socio-demographic-differences-in-access-to-psychological-treatment-services-evidence-from-a-national-cohort-study
#32
JOURNAL ARTICLE
Emma Sharland, Klaudia Rzepnicka, Dorothee Schneider, Katie Finning, Piotr Pawelek, Rob Saunders, Vahé Nafilyan
BACKGROUND: Since 2008, the Improving Access to Psychological Therapies (IAPT) programme has offered adults in England evidence-based psychological treatments for common mental disorders (CMDs) such as depression and anxiety disorders. However, inequalities in access have not been explored at the national level. METHODS: Using a unique individual patient dataset that linked 2011 Census information of English residents to national IAPT data collected between April 2017 and March 2018, we estimated the rate of access by a wide range of socio-demographic characteristics that are not routinely available...
May 17, 2023: Psychological Medicine
https://read.qxmd.com/read/37191029/trying-to-name-what-doesn-t-change-neural-nonresponse-to-cognitive-therapy-for-depression
#33
JOURNAL ARTICLE
Marlene V Strege, John A Richey, Greg J Siegle
BACKGROUND: Theoretical models of neural mechanisms underlying Cognitive Behavior Therapy (CBT) for major depressive disorder (MDD) propose that psychotherapy changes neural functioning of prefrontal cortical structures associated with cognitive-control processes (DeRubeis, Siegle, & Hollon, ); however, MDD is persistent and characterized by long-lasting vulnerabilities to recurrence after intervention, suggesting that underlying neural mechanisms of MDD remain despite treatment. It follows that identification of treatment-resistant aberrant neural processes in MDD may inform clinical and research efforts targeting sustained remission...
May 16, 2023: Psychological Medicine
https://read.qxmd.com/read/37184076/the-usability-of-daytime-and-night-time-heart-rate-dynamics-as-digital-biomarkers-of-depression-severity
#34
JOURNAL ARTICLE
S Siddi, R Bailon, I Giné-Vázquez, F Matcham, F Lamers, S Kontaxis, E Laporta, E Garcia, F Lombardini, P Annas, M Hotopf, B W J H Penninx, A Ivan, K M White, S Difrancesco, P Locatelli, J Aguiló, M T Peñarrubia-Maria, V A Narayan, A Folarin, D Leightley, N Cummins, S Vairavan, Y Ranjan, A Rintala, G de Girolamo, S K Simblett, T Wykes, I Myin-Germeys, R Dobson, J M Haro
BACKGROUND: Alterations in heart rate (HR) may provide new information about physiological signatures of depression severity. This 2-year study in individuals with a history of recurrent major depressive disorder (MDD) explored the intra-individual variations in HR parameters and their relationship with depression severity. METHODS: Data from 510 participants (Number of observations of the HR parameters = 6666) were collected from three centres in the Netherlands, Spain, and the UK, as a part of the remote assessment of disease and relapse-MDD study...
May 15, 2023: Psychological Medicine
https://read.qxmd.com/read/37183659/changing-adolescent-activity-patterns-and-the-correlation-of-self-esteem-and-externalizing-mental-health-symptoms-across-time-results-from-the-usa-from-1991-through-2020
#35
JOURNAL ARTICLE
Noah T Kreski, Melanie S Askari, Magdalena Cerdá, Qixuan Chen, Deborah S Hasin, Silvia S Martins, Pia M Mauro, Mark Olfson, Katherine M Keyes
BACKGROUND: Common adolescent psychiatric symptoms cluster into two dominant domains: internalizing and externalizing. Both domains are linked to self-esteem, which serves as a protective factor against a wide range of internalizing and externalizing problems. This study examined trends in US adolescents' self-esteem and externalizing symptoms, and their correlation, by sex and patterns of time use. METHODS: Using Monitoring the Future data ( N = 338 896 adolescents, grades:8/10/12, years:1991-2020), we generated six patterns of time use using latent profile analysis with 17 behavior items (e...
May 15, 2023: Psychological Medicine
https://read.qxmd.com/read/37183395/depression-and-risk-of-gastrointestinal-disorders-a-comprehensive-two-sample-mendelian-randomization-study-of-european-ancestry
#36
JOURNAL ARTICLE
Dongze Chen, Yali Zhang, Tao Huang, Jinzhu Jia
BACKGROUND: Major depressive disorder (MDD) is clinically documented to co-occur with multiple gastrointestinal disorders (GID), but the potential causal relationship between them remains unclear. We aimed to evaluate the potential causal relationship of MDD with 4 GID [gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), peptic ulcer disease (PUD), and non-alcoholic fatty liver disease (NAFLD)] using a two-sample Mendelian randomization (MR) design. METHODS: We obtained genome-wide association data for MDD from a meta-analysis ( N = 480 359), and for GID from the UK Biobank ( N ranges: 332 601-486 601) and FinnGen ( N ranges: 187 028-218 792) among individuals of European ancestry...
May 15, 2023: Psychological Medicine
https://read.qxmd.com/read/37161895/antipsychotic-medication-for-women-with-schizophrenia-spectrum-disorders-corrigendum
#37
JOURNAL ARTICLE
Bodyl A Brand, Yudith R A Haveman, Franciska de Beer, Janna N de Boer, Paola Dazzan, Iris E C Sommer
No abstract text is available yet for this article.
May 10, 2023: Psychological Medicine
https://read.qxmd.com/read/37161884/methodological-issues-in-social-cognition-research-in-autism-spectrum-disorder-and-schizophrenia-spectrum-disorder-a-systematic-review
#38
REVIEW
Grace E Konstantin, Julie Nordgaard, Mads Gram Henriksen
Recent systematic reviews and meta-analyses conclude that similar social cognitive impairments are found in autism spectrum disorder (ASD) and schizophrenia spectrum disorder (SSD). While methodological issues have been mentioned as a limitation, no study has yet explored the magnitude of methodological heterogeneity across these studies and its potential impact for their conclusion. The purpose of this study was to systematically review studies comparing social cognitive impairments in ASD and SSD with a focus on methodology...
May 10, 2023: Psychological Medicine
https://read.qxmd.com/read/37161705/a-meta-analysis-of-cognitive-interventions-for-patients-with-recent-onset-psychosis-are-they-effective-for-improving-functioning
#39
REVIEW
Eleni Petkari, Natalia Martín-María, Teresa Sánchez-Gutiérrez, Belén Fernández-Castilla, Ana Calvo
The increasing popularity of cognitive interventions for patients with psychosis calls for further exploration on how these interventions may benefit functional outcomes. We conducted a meta-analysis of randomized controlled trials (RCTs) to examine the effectiveness of cognitive interventions (i.e. Cognitive Remediation, Cognitive Training, Social Cognition, and their combination) on functioning of patients with recent onset psychosis, established as the period within the first five years from the first episode...
May 10, 2023: Psychological Medicine
https://read.qxmd.com/read/37161690/a-systematic-review-of-digital-interventions-for-smoking-cessation-in-patients-with-serious-mental-illness
#40
REVIEW
Luis Martinez Agulleiro, Bhagyashree Patil, Joseph Firth, Chelsea Sawyer, Benedikt L Amann, Francina Fonseca, Marta Torrens, Victor Perez, Francisco Xavier Castellanos, John M Kane, Daniel Guinart
Tobacco smoking is highly prevalent among patients with serious mental illness (SMI), with known deleterious consequences. Smoking cessation is therefore a prioritary public health challenge in SMI. In recent years, several smoking cessation digital interventions have been developed for non-clinical populations. However, their impact in patients with SMI remains uncertain. We conducted a systematic review to describe and evaluate effectiveness, acceptability, adherence, usability and safety of digital interventions for smoking cessation in patients with SMI...
May 10, 2023: Psychological Medicine
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