Archives of Otolaryngology - Head & Neck Surgery

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We report a rare parasitic nematode infection in a 26-year-old healthy African American man. Gongylonema nematode infections in humans are unique in their ability to localize in the submucosa of the oral cavity and oropharynx. Humans are incidental hosts for the Gongylonema nematode, which is more commonly found in rudimentary animals, birds, and rodents. Approximately 50 cases of human Gongylonema infections have been reported worldwide, including 11 documented cases in the United States.(1) The pathogenesis, characteristic clinic findings, and identification features will be discussed...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

OBJECTIVE: To objectively determine changes in sensorineural hearing in children with mucopolysaccharidosis (MPS) by comparing audiological data before and after hematopoietic stem cell transplantation (HSCT). DESIGN: Retrospective medical chart analysis. SETTING: Tertiary referral hospital. PATIENTS: Thirty pediatric patients with the diagnosis of MPS who underwent HSCT and had audiological data before and after HSCT...

OBJECTIVE: To determine whether intranasal theophylline methylpropyl paraben can correct hyposmia and hypogeusia. DESIGN: We performed an open-label pilot study in patients with hyposmia and hypogeusia under the following 3 conditions: (1) before treatment, (2) after oral theophylline anhydrous treatment, and (3) after intranasal theophylline treatment. Under each condition, we performed subjective evaluations of taste and smell functions, quantitative measurements of taste (gustometry) and smell (olfactometry), and measurements of serum theophylline level and body weight...

OBJECTIVES: To characterize levels of tumor necrosis factor (TNF; formerly known as tumor necrosis factor α), a well-established proinflammatory cytokine, in patients with immune-mediated sensorineural hearing loss (IM-SNHL) and to determine the role of this cytokine in identifying steroid-responsive hearing loss. DESIGN: Prospective case-control study. SETTING: Tertiary care academic medical center. PATIENTS: A total of 11 control subjects and 85 patients with clinical and audiometric characteristics of IM-SNHL (autoimmune inner ear disease and sudden SNHL combined) treated with corticosteroids were enrolled in the study...

OBJECTIVE: To assess the efficacy of upper airway surgical intervention in patients with Prader-Willi syndrome (PWS). Due to reports of sudden death in children undergoing treatment with growth hormone for PWS, detection of sleep-disordered breathing by polysomnography (PSG) has been recommended. DESIGN: Retrospective study. SETTING: Multidisciplinary PWS Center at a tertiary care children's hospital. PATIENTS: Thirteen pediatric patients with PWS who underwent adenotonsillectomy (T&A) with pre-PSG and post-PSG...

OBJECTIVE: To determine the value of positron emission tomography (PET) with contrast-enhanced computed tomography (CT) in assessing the need for neck dissection by retrospectively reviewing the pathology reports of patients with human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (SCC). DESIGN: Retrospective cohort study. SETTING: Tertiary medical center. PATIENTS: Seventy-seven patients with HPV-related SCC...

OBJECTIVE: To determine whether invasion of the pharyngeal constrictor muscle in early squamous cell carcinoma of the tonsil is correlated with lymph node metastasis. DESIGN: Retrospective analysis of medical records and pathology specimens. SETTING: Tertiary care referral center. PATIENTS: Forty-eight patients who were diagnosed as having T2 squamous cell carcinoma of the tonsil and who underwent surgery. They were divided into 2 groups: an invasive group with invasion of the pharyngeal constrictor muscle and a noninvasive group without invasion of the pharyngeal constrictor muscle...

OBJECTIVE: To identify predictors of levels II and Vb involvement in papillary thyroid cancer (PTC) with lateral neck metastasis. DESIGN: Large case series. SETTING: High-volume tertiary care hospital. PATIENTS: Consecutive sample of 185 patients who underwent 248 selective neck dissections of at least levels II to V for pathologically proven PTC. MAIN OUTCOME MEASURES: Significant independent predictors of level II and Vb metastasis, including age and pathologic variables (tumor diameter, dominant nodule cellular pathology, multifocality, extracapsular invasion, positive margins, and lymphovascular invasion)...

OBJECTIVE: To determine the association between safety-net hospital care and short-term outcomes after head and neck cancer surgery. DESIGN: Cross-sectional analysis. Safety-net burden was calculated as the percentage of patients with head and neck cancer with Medicaid or no insurance. SETTING: Nationwide Inpatient Sample database. PATIENTS: Adults who underwent an ablative procedure for a malignant oral cavity, laryngeal, hypopharyngeal, or oropharyngeal neoplasm in 2001 through 2008...

One of the highest honors of one's career is to be asked to address colleagues, mentors, and students who represent the world's leading health professionals dedicated to reducing the morbidity and mortality associated with head and neck cancer. Hayes Martin would certainly share this feeling of honor and humility in having a lecture given in his name on the occasion of the Eighth International Conference on Head and Neck Cancer. I am so very pleased to share with you some thoughts on the assessment, adequacy, and application of surgical resection margins in an era in which personalized surgery and molecular medicine will have a major impact on patient outcomes...

OBJECTIVE To investigate whether training otorhinolaryngology residents to criterion performance levels (proficiency) on the Endoscopic Sinus Surgery Simulator produces individuals whose performance in the operating room is at least equal to those who are trained by performing a fixed number of surgical procedures. DESIGN Prospective cohort. SETTING Two academic medical centers in New York City. PARTICIPANTS Otorhinolaryngology junior residents composed of 8 experimental subjects and 6 control subjects and 6 attending surgeons...

OBJECTIVE To determine the prevalence and diagnostic usefulness of the "spoke sign" (SS), a specific otoscopic finding, in detecting the presence of pediatric middle ear effusion (MEE). METHODS The SS was defined as a dull gray appearance of the tympanic membrane with engorged vasculature in an arrangement similar to the spokes of a bicycle wheel, covering 50% or more of the inferior tympanic membrane by area. An observational screening test study was performed prospectively with enrollment of consecutive pediatric patients scheduled for tympanostomy tube placement...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.