Hollie Speake, Anastasia Phillips, Tracie Chong, Chisha Sikazwe, Avram Levy, Jurissa Lang, Benjamin Scalley, David J Speers, David W Smith, Paul Effler, Suzanne P McEvoy
To investigate potential transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during a domestic flight within Australia, we performed epidemiologic analyses with whole-genome sequencing. Eleven passengers with PCR-confirmed SARS-CoV-2 infection and symptom onset within 48 hours of the flight were considered infectious during travel; 9 had recently disembarked from a cruise ship with a retrospectively identified SARS-CoV-2 outbreak. The virus strain of those on the cruise and the flight was linked (A2-RP) and had not been previously identified in Australia...
September 29, 2020: Emerging Infectious Diseases
Robert Moss, James Wood, Damien Brown, Freya M Shearer, Andrew J Black, Kathryn Glass, Allen C Cheng, James M McCaw, Jodie McVernon
The ability of health systems to cope with coronavirus disease (COVID-19) cases is of major concern. In preparation, we used clinical pathway models to estimate healthcare requirements for COVID-19 patients in the context of broader public health measures in Australia. An age- and risk-stratified transmission model of COVID-19 demonstrated that an unmitigated epidemic would dramatically exceed the capacity of the health system of Australia over a prolonged period. Case isolation and contact quarantine alone are insufficient to constrain healthcare needs within feasible levels of expansion of health sector capacity...
September 28, 2020: Emerging Infectious Diseases
Gabriella L Morley, Stephen Taylor, Sian Jossi, Marisol Perez-Toledo, Sian E Faustini, Edith Marcial-Juarez, Adrian M Shields, Margaret Goodall, Joel D Allen, Yasunori Watanabe, Maddy L Newby, Max Crispin, Mark T Drayson, Adam F Cunningham, Alex G Richter, Matthew K O'Shea
Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.
September 24, 2020: Emerging Infectious Diseases
Lara J Akinbami, Nga Vuong, Lyle R Petersen, Samira Sami, Anita Patel, Susan L Lukacs, Lisa Mackey, Lisa A Grohskopf, Amy Shehu, Jenny Atas
To estimate seroprevalence of severe acute respiratory syndrome 2 (SARS-CoV-2) among healthcare, first response, and public safety personnel, antibody testing was conducted in emergency medical service agencies and 27 hospitals in the Detroit, Michigan, USA, metropolitan area during May-June 2020. Of 16,403 participants, 6.9% had SARS-CoV-2 antibodies. In adjusted analyses, seropositivity was associated with exposure to SARS-CoV-2-positive household members (adjusted odds ratio [aOR] 6.18, 95% CI 4.81-7.93) and working within 15 km of Detroit (aOR 5...
September 21, 2020: Emerging Infectious Diseases
Xutong Wang, Zhanwei Du, George Huang, Remy F Pasco, Spencer J Fox, Alison P Galvani, Michael Pignone, S Claiborne Johnston, Lauren Ancel Meyers
As coronavirus disease spreads throughout the United States, policymakers are contemplating reinstatement and relaxation of shelter-in-place orders. By using a model capturing high-risk populations and transmission rates estimated from hospitalization data, we found that postponing relaxation will only delay future disease waves. Cocooning vulnerable populations can prevent overwhelming medical surges.
September 21, 2020: Emerging Infectious Diseases
Susanne Homolka, Laura Paulowski, Sönke Andres, Doris Hillemann, Ruwen Jou, Gunar Günther, Mareli Claassens, Martin Kuhns, Stefan Niemann, Florian P Maurer
In many settings, the ongoing coronavirus (COVID-19) pandemic coincides with other major public health threats, in particular tuberculosis. Using tuberculosis (TB) molecular diagnostic infrastructure, which has substantially expanded worldwide in recent years, for COVID-19 case-finding might be warranted. We analyze the potential of using TB diagnostic and research infrastructures for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. We focused on quality control by adapting the 12 Quality System Essentials framework to the COVID-19 and TB context...
September 21, 2020: Emerging Infectious Diseases
Edward M Choi, Daniel K W Chu, Peter K C Cheng, Dominic N C Tsang, Malik Peiris, Daniel G Bausch, Leo L M Poon, Deborah Watson-Jones
Four persons with severe acute respiratory syndrome coronavirus 2 infection had traveled on the same flight from Boston, Massachusetts, USA, to Hong Kong, China. Their virus genetic sequences are identical, unique, and belong to a clade not previously identified in Hong Kong, which strongly suggests that the virus can be transmitted during air travel.
September 18, 2020: Emerging Infectious Diseases
Nguyen Cong Khanh, Pham Quang Thai, Ha-Linh Quach, Ngoc-Anh Hoang Thi, Phung Cong Dinh, Tran Nhu Duong, Le Thi Quynh Mai, Ngu Duy Nghia, Tran Anh Tu, La Ngoc Quang, Tran Dai Quang, Trong-Tai Nguyen, Florian Vogt, Dang Duc Anh
To assess the role of in-flight transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we investigated a cluster of cases among passengers on a 10-hour commercial flight. Affected persons were passengers, crew, and their close contacts. We traced 217 passengers and crew to their final destinations and interviewed, tested, and quarantined them. Among the 16 persons in whom SARS-CoV-2 infection was detected, 12 (75%) were passengers seated in business class along with the only symptomatic person (attack rate 62%)...
September 18, 2020: Emerging Infectious Diseases
Vanessa R Barrs, Malik Peiris, Karina W S Tam, Pierra Y T Law, Christopher J Brackman, Esther M W To, Veronica Y T Yu, Daniel K W Chu, Ranawaka A P M Perera, Thomas H C Sit
We tested 50 cats from coronavirus disease households or close contacts in Hong Kong, China, for severe acute respiratory syndrome coronavirus 2 RNA in respiratory and fecal samples. We found 6 cases of apparent human-to-feline transmission involving healthy cats. Virus genomes sequenced from 1 cat and its owner were identical.
September 16, 2020: Emerging Infectious Diseases
Pawinee Doung-Ngern, Repeepong Suphanchaimat, Apinya Panjangampatthana, Chawisar Janekrongtham, Duangrat Ruampoom, Nawaporn Daochaeng, Napatchakorn Eungkanit, Nichakul Pisitpayat, Nuengruethai Srisong, Oiythip Yasopa, Patchanee Plernprom, Pitiphon Promduangsi, Panita Kumphon, Paphanij Suangtho, Peeriya Watakulsin, Sarinya Chaiya, Somkid Kripattanapong, Thanawadee Chantian, Emily Bloss, Chawetsan Namwat, Direk Limmathurotsakul
We evaluated effectiveness of personal protective measures against severe acute respiratory disease coronavirus 2 (SARS-CoV-2) infection. Our case-control study included 211 cases of coronavirus disease (COVID-19) and 839 controls in Thailand. Cases were defined as asymptomatic contacts of COVID-19 patients who later tested positive for SARS-CoV-2; controls were asymptomatic contacts who never tested positive. Wearing masks all the time during contact was independently associated with lower risk for SARS-CoV-2 infection compared with not wearing masks; wearing a mask sometimes during contact did not lower infection risk...
September 15, 2020: Emerging Infectious Diseases
Rachel L Byrne, Grant A Kay, Konstantina Kontogianni, Ghaith Aljayyoussi, Lottie Brown, Andrea M Collins, Luis E Cuevas, Daniela M Ferreira, Alice J Fraser, Gala Garrod, Helen Hill, Grant L Hughes, Stefanie Menzies, Elena Mitsi, Sophie I Owen, Edward I Patterson, Christopher T Williams, Angela Hyder-Wright, Emily R Adams, Ana I Cubas-Atienzar
PCR of upper respiratory specimens is the diagnostic standard for severe acute respiratory syndrome coronavirus 2 infection. However, saliva sampling is an easy alternative to nasal and throat swabbing. We found similar viral loads in saliva samples and in nasal and throat swab samples from 110 patients with coronavirus disease.
September 11, 2020: Emerging Infectious Diseases
Giovanni Battista Migliori, Pei Min Thong, Onno Akkerman, Jan-Willem Alffenaar, Fernando Álvarez-Navascués, Mourtala Mohamed Assao-Neino, Pascale Valérie Bernard, Joshua Sorba Biala, François-Xavier Blanc, Elena M Bogorodskaya, Sergey Borisov, Danilo Buonsenso, Marianne Calnan, Paola Francesca Castellotti, Rosella Centis, Jeremiah Muhwa Chakaya, Jin-Gun Cho, Luigi Ruffo Codecasa, Lia D'Ambrosio, Justin Denholm, Martin Enwerem, Maurizio Ferrarese, Tatiana Galvão, Marta García-Clemente, José-María García-García, Gina Gualano, José Antonio Gullón-Blanco, Sandra Inwentarz, Giuseppe Ippolito, Heinke Kunst, Andrei Maryandyshev, Mario Melazzini, Fernanda Carvalho de Queiroz Mello, Marcela Muñoz-Torrico, Patrick Bung Njungfiyini, Domingo Juan Palmero, Fabrizio Palmieri, Pavilio Piccioni, Alberto Piubello, Adrian Rendon, Josefina Sabriá, Matteo Saporiti, Paola Scognamiglio, Samridhi Sharma, Denise Rossato Silva, Mahamadou Bassirou Souleymane, Antonio Spanevello, Eva Tabernero, Marina Tadolini, Michel Eke Tchangou, Alice Boi Yatta Thornton, Simon Tiberi, Zarir F Udwadia, Giovanni Sotgiu, Catherine Wei Min Ong, Delia Goletti
Coronavirus disease has disrupted tuberculosis services globally. Data from 33 centers in 16 countries on 5 continents showed that attendance at tuberculosis centers was lower during the first 4 months of the pandemic in 2020 than for the same period in 2019. Resources are needed to ensure tuberculosis care continuity during the pandemic.
September 11, 2020: Emerging Infectious Diseases
Jianyun Lu, Zhicong Yang
No abstract text is available yet for this article.
September 11, 2020: Emerging Infectious Diseases
Ana M Rule
No abstract text is available yet for this article.
September 11, 2020: Emerging Infectious Diseases
Matthew Biggerstaff, Benjamin J Cowling, Zulma M Cucunubá, Linh Dinh, Neil M Ferguson, Huizhi Gao, Verity Hill, Natsuko Imai, Michael A Johansson, Sarah Kada, Oliver Morgan, Ana Pastore Y Piontti, Jonathan A Polonsky, Pragati Venkata Prasad, Talia M Quandelacy, Andrew Rambaut, Jordan W Tappero, Katelijn A Vandemaele, Alessandro Vespignani, K Lane Warmbrod, Jessica Y Wong
We report key epidemiologic parameter estimates for coronavirus disease identified in peer-reviewed publications, preprint articles, and online reports. Range estimates for incubation period were 1.8-6.9 days, serial interval 4.0-7.5 days, and doubling time 2.3-7.4 days. The effective reproductive number varied widely, with reductions attributable to interventions. Case burden and infection fatality ratios increased with patient age. Implementation of combined interventions could reduce cases and delay epidemic peak up to 1 month...
September 11, 2020: Emerging Infectious Diseases
William T Hu, J Christina Howell, Tugba Ozturk, Karima Benameur, Leda C Bassit, Richard Ramonell, Kevin S Cashman, Shama Pirmohammed, John D Roback, Vincent C Marconi, Irene Yang, Valerie V Mac, Daniel Smith, Ignasio Sanz, Whitney Wharton, F Eun-Hyung Lee, Raymond F Schinazi
Among patients with coronavirus disease (COVID-19), IgM levels increased early after symptom onset for those with mild and severe disease, but IgG levels increased early only in those with severe disease. A similar pattern was observed in a separate serosurveillance cohort. Mild COVID-19 should be investigated separately from severe COVID-19.
August 28, 2020: Emerging Infectious Diseases
Anuradha Chowdhary, Bansidhar Tarai, Ashutosh Singh, Amit Sharma
In New Delhi, India, candidemia affected 15 critically ill coronavirus disease patients admitted to an intensive care unit during April-July 2020. Candida auris accounted for two thirds of cases; case-fatality rate was high (60%). Hospital-acquired C. auris infections in coronavirus disease patients may lead to adverse outcomes and additional strain on healthcare resources.
August 27, 2020: Emerging Infectious Diseases
Ngai-Sze Wong, Chi-Chiu Leung, Shui-Shan Lee
The onset of the 2019-20 winter influenza season in Hong Kong coincided with the emergence of the coronavirus disease epidemic in neighboring mainland China. After widespread adoption of large-scale social distancing interventions in response to the impending coronavirus disease outbreak, the influenza season ended abruptly with a decrease to a low trough.
August 27, 2020: Emerging Infectious Diseases
So Yeon Kim, Jaehyeon Lee, Heungsup Sung, Hyukmin Lee, Myung Guk Han, Cheon Kwon Yoo, Sang Won Lee, Ki Ho Hong
To validate the specimen-pooling strategy for real-time reverse transcription PCR detection of severe acute respiratory syndrome coronavirus 2, we generated different pools including positive specimens, reflecting the distribution of cycle threshold values at initial diagnosis. Cumulative sensitivities of tested pool sizes suggest pooling of <6 specimens for surveillance by this method.
August 26, 2020: Emerging Infectious Diseases
(no author information available yet)
To improve understanding of coronavirus disease (COVID-19), we assessed the epidemiology of an outbreak on a cruise ship, February 5-24, 2020. The study population included persons on board on February 3 (2,666 passengers, 1,045 crew). Passengers had a mean age of 66.1 years and were 55% female; crew had a mean age of 36.6 years and were 81% male. Of passengers, 544 (20.4%) were infected, 314 (57.7%) asymptomatic. Attack rates were highest in 4-person cabins (30.0%; n = 18). Of crew, 143 (13.7%) were infected, 64 (44...
August 21, 2020: Emerging Infectious Diseases
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