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International Journal of Colorectal Disease
Ruiqi Li, Jiajie Zhou, Shuai Zhao, Qiannan Sun, Daorong Wang
BACKGROUND: Postoperative anastomotic leakage for rectal cancer shows higher morbidity with grievous concomitant symptoms. Accurate assessment of the incidence of anastomotic leakage, multivariate analysis, and establishment of a scientific prediction model can be useful to dispose of its possible severe clinical consequences. METHODS: This retrospective study collected 1995 consecutive patients who underwent anterior resection of rectal cancer with primary anastomosis at Northern Jiangsu People's Hospital between January 2016 and June 2022...
May 22, 2023: International Journal of Colorectal Disease
Pasquale Scognamiglio, Anja Seeger, Matthias Reeh, Nathaniel Melling, Karl F Karstens, Thomas Rösch, Jakob R Izbicki, Marcus Kantowski, Michael Tachezy
PURPOSE: The treatment of anastomotic leakage after left colorectal surgery remains challenging. Since its introduction, endoscopic negative pressure therapy (ENPT) has proven to be advantageous, reducing the necessity of surgical revision. The aim of our study is to present our experience with endoscopic treatment of colorectal leakages and to identify potential factors influencing treatment outcome. METHODS: Patients who underwent endoscopic treatment of colorectal leakage were retrospectively analyzed...
May 19, 2023: International Journal of Colorectal Disease
Michiyo Yamazaki, Hsingwen Chung, Youran Xu, Hong Qiu
PURPOSE: To estimate and compare annual prevalence and incidence, and demographic characteristics of patients with ulcerative colitis (UC) in Japan and the United States (US). METHODS: All patients with UC were identified from large employment-based healthcare claims databases (Japan Medical Data Center [JMDC] in Japan and IBM MarketScan Commercial Claims and Encounters database [CCAE] in the US), from 2010 to 2019. Cases were confirmed using International Classification of Disease-9/10 codes with/without Anatomical Therapeutic Chemical codes...
May 19, 2023: International Journal of Colorectal Disease
Ameya Deshmukh, Parth M Desai, Timothy Chrusciel, Eugene Nwankwo, Rohan Tripathi, Antonio R Cheesman
BACKGROUND: Despite inflammatory bowel disease's (IBD) association with hepatobiliary disorders and the use of endoscopic retrograde cholangiopancreatography (ERCP) for both diagnostic and therapeutic evaluation of these diseases, it remains a poorly studied area within the literature. The purpose of this study is to examine the effect of IBD on the occurrence of adverse events (AE) pertaining to ERCP. METHODS: This project utilized the National Inpatient Sample (NIS) database, the largest inpatient database in the USA...
May 19, 2023: International Journal of Colorectal Disease
Wentao Liu, Jian Gong, Li Gu
PURPOSE: The optimal technique for removing small colorectal polyps ranging from 5 to 10 mm in size remains uncertain. In order to compare the efficacy and adverse events between cold snare polypectomy (CSP) and hot snare polypectomy (HSP) for removing small polyps, we conducted a systematic review and meta-analysis of available randomized controlled trials. METHODS: We conducted a comprehensive search of MEDLINE, EMBASE, and the Cochrane Library databases from 1998 to May 2023 to identify randomized controlled trials that evaluated the efficacy and safety of cold snare polypectomy (CSP) and hot snare polypectomy (HSP) for resecting small colorectal polyps...
May 19, 2023: International Journal of Colorectal Disease
Hualin Liao, Tengyu Zeng, Xianqiang Xie, Jiyang Li, Dongsheng Li, KejinYan, Fan Chen, Hongliang Zhu
PURPOSE: Adjuvant chemotherapy is controversial in rectal cancer, especially after neoadjuvant chemoradiotherapy (NCRT). This retrospective study aims at evaluating adjuvant chemotherapy's long-term survival benefits in stage II and stage III rectal adenocarcinoma (RC). METHODS: This study obtained data from the Surveillance, Epidemiology, and End Results (SEER) database registered between 2010 and 2015. The survival analyses used the Kaplan-Meier method and were compared by log-rank test...
May 18, 2023: International Journal of Colorectal Disease
Michal Perets, Shlomo Yellinek, Ofra Carmel, Elad Boaz, Amir Dagan, Nir Horesh, Petachia Reissman, Michael R Freund
PURPOSE: To assess whether full bowel preparation affects 30-day surgical outcomes in laparoscopic right colectomy for colon cancer. METHODS: A retrospective chart review of all elective laparoscopic right colectomies performed for colonic adenocarcinoma between Jan 2011 and Dec 2021. The cohort was divided into two groups-no bowel preparation (NP) group and patients who received full bowel preparation (FP), including oral and mechanical cathartic bowel preparation...
May 17, 2023: International Journal of Colorectal Disease
Shufa Tan, Yan Ou, Shuilan Huang, Qiangqiang Gao
BACKGROUND: Radical resection is typically the standard treatment for early- and mid-stage rectal cancer as local resection may result in a high rate of recurrence and risk of distant metastasis. A growing number of studies have shown that local excision after neoadjuvant chemotherapy or chemoradiotherapy can significantly reduce recurrence rates and is a feasible strategy to preserve the rectum as an alternative to conventional radical resection. OBJECTIVE: This study aims to compare the efficacy of local resection after neoadjuvant chemotherapy or chemoradiotherapy with radical surgery for early- and mid-stage rectal cancer and to report the evidence-based clinical advantages of both techniques...
May 16, 2023: International Journal of Colorectal Disease
Xiangyu Zhang, Liang Zhao, Yanpeng Hu, Kai Deng, Wanbo Ren
BACKGROUND: Synchronous multiple primary colorectal cancer (SMPCC) involves the simultaneous occurrence of 2 or more independent primary malignant tumors in the colon or rectum. Although SMPCC is rare, it results in a higher incidence of postoperative complications and mortality compared to patients with single primary colorectal cancer (SPCRC). METHODS: The clinical factors and survival outcomes of SMPCC patients registered on the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2017 were extracted...
May 16, 2023: International Journal of Colorectal Disease
M Levaillant, A Venara, H Damon, L Siproudhis, C Brochard, J F Hamel
PURPOSE: The incidence of severe faecal incontinence (FI) in young people is likely underestimated. The objective of this study is to assess the incidence of FI by using the French national insurance information system (SNDS). METHODS: The SNDS was used, including 2 health insurance claims databases. The study included 49,097,454 French people who were ≥ 20 years old in 2019. The main outcome measure was the occurrence of FI. RESULTS: In 2019, 123,630 patients out of the entire French population (n = 49 097 454) (0...
May 16, 2023: International Journal of Colorectal Disease
Rikke Bech Hansen, Rogini Balachandran, Thomas Nikolas Valsamidis, Lene Hjerrild Iversen
PURPOSE: Anastomotic leakage after colorectal cancer resection is a feared postoperative complication seen among up till 10-20% of patients, with a higher risk following rectal resection than colon resection. Recent studies suggest that the combined use of preoperative mechanical bowel preparation and oral antibiotics may have a preventive effect on anastomotic leakage. This systematic review aims to explore the association between preoperative mechanical bowel preparation combined with oral antibiotics and the risk of anastomotic leakage following restorative resection for primary rectal cancer...
May 15, 2023: International Journal of Colorectal Disease
Yupei Liu, Zhiyi Sun, Yinyun Guo, Chuan Liu, Shan Tian, Weiguo Dong
PURPOSE: This study aimed to investigate the risk and prognostic factors of lymph node metastasis (LNM) in early-onset colorectal cancer (EO-CRC) and to develop nomograms for quantitatively predicting LNM and the cancer-specific survival (CSS). METHODS: A total of 22,405 EO-CRC patients were included in this study using the SEER database from 2010 to 2017. Logistic and Cox regression were used to identify risk and the potential prognostic factors, respectively, for EO-CRC with LNM...
May 15, 2023: International Journal of Colorectal Disease
Dadi Vilhjalmsson, Mattias Lepsenyi, Ingvar Syk, Anders Grönberg, Henrik Thorlacius
PURPOSE: C-REX is a novel instrument for creating stapleless colorectal anastomosis by compression. The aim of this study was to evaluate the feasibility and effectiveness of C-REX in open and laparoscopic high anterior resections. METHODS: A prospective clinical safety study on 21 patients reconstructed with C-REX colorectal anastomosis following high anterior resection of the sigmoid colon using two different devices for intraabdominal (n = 6) or transanal (n = 15) placement of the anastomotic rings...
May 13, 2023: International Journal of Colorectal Disease
Margherita Rotondi, Giuseppe Facondo, Stefano Mossa, Gianluca Vullo, Ilaria Angelicone, Maurizio Valeriani, Mattia Falchetto Osti
PURPOSE: To compare toxicity of radiotherapy (RT) with concomitant chemotherapy (CHT) in patients (pts) with anal cancer treated with simultaneous integrated boost (SIB) versus sequential boost (SeqB). METHODS: Sixty-six patients were treated from 2007 to 2021. Thirty patients underwent to SeqB concurrent to CHT and 37 to SIB-group. Toxicity assessment has been considered in acute and in late toxicities for gastrointestinal (GI), genitourinary (GU), cutaneous (CU) districts, according to Common Terminology Criteria for Adverse Events (CTCAE), Version 5...
May 12, 2023: International Journal of Colorectal Disease
Wuli Tang, Gang Xie, Danni Wang, Ting Li, Yitao Ren, Junlin Li, Jiaxing Deng, Kang Li
BACKGROUND AND AIMS: Body composition changes in patients with Crohn's disease (CD) have received increasing attention in recent years. This review aims to describe the changes in body composition in patients with CD on imaging and to analyze and summarize the prognostic value of body composition. METHODS: We systematically searched Web of Science, PubMed, Embase, Cochrane Library, and Medline via OVID for literature published before November 2022, and two researchers independently evaluated the quality of the retrieved literature...
May 12, 2023: International Journal of Colorectal Disease
Yasuhiro Takano, Keita Kodera, Shu Tsukihara, Sumika Takahashi, Kobayashi Yasunobu, Hironori Kanno, Ryota Saito, Nobuyoshi Hanyu
PURPOSE: Incisional hernia is a common complication after abdominal surgery, especially in obese patients. The aim of the present study was to evaluate the relationship between sarcobesity and incisional hernia development after laparoscopic colorectal cancer surgery. METHODS: In total, 262 patients who underwent laparoscopic colorectal cancer surgery were included in the present study. Univariate and multivariate analyses were performed to evaluate the independent risk factors for the development of incisional hernia...
May 11, 2023: International Journal of Colorectal Disease
Jinjing Huang
No abstract text is available yet for this article.
May 10, 2023: International Journal of Colorectal Disease
Marianna Alessandra Gerardi, Maria Alessia Zerella, Luca Bergamaschi, Annamaria Ferrari, Simona Arculeo, Vincenzo Bagnardi, Samuele Frassoni, Wanda Petz, Cristiana Fodor, Francesca Emiro, Federica Cattani, Maria Cristina Leonardi, Maria Giulia Zampino, Barbara Alicja Jereczek-Fossa
PURPOSE: To evaluate oncological outcomes and late toxicities in a retrospective series of patients with locally-extended anal squamous cell carcinoma (ASCC), treated with curative Intensity Modulated Radiotherapy (IMRT) and chemotherapy. METHODS: ASCC patients who underwent chemo-radiotherapy with IMRT from 2010 to 2020 were included. Oncological outcomes were assessed in terms of overall survival (OS), disease-free survival (DFS), colostomy-free survival (CFS) and event-free survival (EFS)...
May 10, 2023: International Journal of Colorectal Disease
Liang Han, Yongzhong Guo, Dunqiang Ren, Hui Hui, Na Li, Xiaoxuan Xie
PURPOSE: This meta-analysis is aimed at understanding the potential role of circulating C-reactive protein (CRP) in the prediction of colorectal cancer (CRC) risk and the potential effect of relevant variables, with specific concern to determine the incorporation of CRP into a CRC risk prediction model. METHODS: Relevant articles on the association between circulating CRP and CRC risk were searched from PubMed, Embase, Web of Science, and Cochrane Database of Systematic Reviews through August 2022...
May 9, 2023: International Journal of Colorectal Disease
Riccardo Urgesi, Cristiano Pagnini, Fernando De Angelis, Maria Carla Di Paolo, Lorella Pallotta, Gianfranco Fanello, Giuseppe Villotti, Mario Alessandro Vitale, Paola Battisti, Maria Giovanna Graziani
BACKGROUND: Videocapsule endoscopy (VCE) is considered the gold standard for overt and obscure gastrointestinal bleeding (OGIB), after negative upper and lower endoscopy. Nonetheless, VCE's diagnostic yield is suboptimal, and it represents a costly, time-consuming, and often not easily available technique. In order to evaluate bleeding risk in patients with atrial fibrillation, several scoring systems have been proposed, but their utilization outside the original clinical setting has rarely been explored...
May 9, 2023: International Journal of Colorectal Disease
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