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International Journal of Colorectal Disease
Andreas Völkerer, Sarah Wernly, Georg Semmler, Maria Flamm, Elmar Aigner, Christian Datz, Bernhard Wernly
BACKGROUND: There is a hypothesis of an association between diverticulosis and metabolic syndrome (MS) or its components, but data on this topic are inconsistent, and a systematic review has not been performed. We conducted a systematic review to investigate the possible association between cardiometabolic risk factors and diverticulosis. METHODS: A systematic literature search was conducted via PubMed, Cochrane Library, and Web of Science in December 2022 to collect the necessary data...
September 19, 2023: International Journal of Colorectal Disease
S L Kampman, B P Smalbroek, L M Dijksman, A B Smits
PURPOSE: Surgical removal of the cancerous tissue remains the cornerstone of curative treatment for colorectal cancer and results in an inflammatory response. An exaggerated inflammatory response has been implicated in the promotion of tumor proliferation and has shown associations with postoperative complications. Literature on the preferred surgical technique to minimize inflammatory response is inconclusive. Therefore, the aim of this study was to assess the inflammatory response and postoperative incidence of infectious complications following surgery for colorectal cancer...
September 19, 2023: International Journal of Colorectal Disease
Jawad Ahmad Zahid, Adile Orhan, Noor Al-Huda Hadi, Sarah Ekeloef, Ismail Gögenur
PURPOSE: Myocardial injury after noncardiac surgery (MINS) is associated with increased mortality and postoperative complications. In patients with colorectal cancer (CRC), postoperative complications are a risk factor for cancer recurrence and disease-free survival. This study investigates the association between MINS and long-term oncological outcomes in patients with CRC in an ERAS setting. METHODS: This retrospective cohort study was conducted at Zealand University Hospital, Denmark, between June 2015 and July 2017...
September 19, 2023: International Journal of Colorectal Disease
Hualin Liao, Tao Li, Yahang Liang, Yaxiong Liu, Yuli Yuan, Mingming Li, Aidi Li, Yang Liu, Yao Yao, Taiyuan Li
PURPOSE: The oncological role of adjuvant chemotherapy (ACT) remains debated in locally advanced rectal cancer (RC) after neoadjuvant therapy (NAT), especially ypI RC. In this study, we used population-based data to evaluate the benefits of ACT in stage ypI RC after NAT and surgery. Moreover, we tried to differentiate what kind of NAT (radiotherapy alone or chemoradiotherapy) was administered because this may affect the further efficacy of ACT. METHODS: All patients with stage ypI primary rectal malignancy were diagnosed in the SEER database between 2004 and 2017...
September 19, 2023: International Journal of Colorectal Disease
Yan Wang, Xia Shen, Pengfei Wang
OBJECTIVE: The association between constipation and depression or suicidal ideation (SI) has not been adequately studied. This study aims to examine whether constipation is associated with depression or SI in US adults. METHOD: 4,562 adults aged 20 and older were selected from the National Health and Nutrition Examination Survey 2009-2010 for the sample. The Bowel Health Questionnaire provided constipation information. Clinical depression and depression severity were assessed by the validated Patient Health Questionnaide-9 (PHQ-9), and item 9 of the PHQ-9 assessed SI...
September 15, 2023: International Journal of Colorectal Disease
Mehment Alperen Avci, Can Akgün, Mustafa Safa Uyanik
AIMS: Acute appendicitis is a common cause of acute abdomen in general surgery and early diagnosis is crucial for prognosis. Abnormal urinalysis results have been associated with appendicitis in some studies, with reports of microscopic hematuria or pyuria in laboratory tests. The aim of this article is to evaluate the relationship between laboratory findings of hematuria, pyuria, and the location of acute appendicitis. METHODS: This retrospective study included 577 patients who underwent appendectomy for suspected acute appendicitis between January 1, 2018, and December 31, 2022, at the general surgery clinic of Samsun Training and Research Hospital...
September 15, 2023: International Journal of Colorectal Disease
Tuane Colles, Patrícia K Ziegelmann, Daniel C Damin
PURPOSE: Anal bleeding is a frequent complaint in the coloproctological practice. Although usually associated with common anorectal disorders, it may represent a sign of an occult colorectal carcinoma. Our purpose was to evaluate the accuracy of the colonoscopy for detection of neoplastic lesions in patients under 50 years of age with rectal bleeding. METHODS: This systematic review and meta-analysis searched publications in PubMed, Web of Science, and Cochrane Library databases up to August, 2023...
September 15, 2023: International Journal of Colorectal Disease
Emre Özoran, İbrahim Halil Özata, Derya Salim Uymaz, Nail Omarov, Emre Bozkurt, Tutku Tüfekçi, Salih Nafiz Karahan, Bülent Gürbüz, Fatih Selçukbiricik, Yasemin Bölükbaşı, Orhun Çığ Taşkın, Bengi Gürses, Ahmet Rencüzoğulları, Dursun Buğra, Emre Balık
PURPOSE: This study aimed to compare local regrowth rates after total neoadjuvant therapy (TNT) versus standard neoadjuvant chemoradiotherapy (SNCRT) in locally advanced rectal cancer (LARC) patients that were strictly selected and assessed with a multimodal approach. Secondary outcomes were 4-year disease-free (DFS) and overall survival (OS) rates. METHODS: Locally advanced rectal cancer patients without distant metastases treated at Koç Healthcare Group between January 2014 and January 2021 were included...
September 14, 2023: International Journal of Colorectal Disease
Hui Zhang, Minghao Lin, Zheng Nan, Yiwen Zhang, Shilin Liu, Andong Li, Guofeng Li
PURPOSE: To evaluate the effect of different surgical methods in the treatment of high complex anal fistula by systematic review and network meta-analysis. METHODS: Randomized controlled trials that met the inclusion criteria in PubMed, Cochrane Library, Embase, Web of Science, CBM, CNKI, WANFANG DATA, VIP were searched from the date of database construction to May 23, 2023. RESULTS: Among the 48 randomized controlled trials (RCTs), 4205 patients were included in the network meta-analysis...
September 14, 2023: International Journal of Colorectal Disease
Xinzhu Zhao, Shuyuan Wang, Zhen Yuan, Suying Yan, Wenwen Pang, Xinyu Liu, Wanting Wang, Ben Yi, Qiurong Han, Qinghuai Zhang, Xipeng Zhang, Chunze Zhang
OBJECTIVES: With the intention of providing a reference for secondary prevention, our study provides some insight on diagnostic yield of factors influencing compliance with colonoscopy and the presence of advanced adenomas (AA). METHODS: We conducted large-scale CRC screening among local Tianjin residents aged 40-75 years between 2012 and 2019. A high-risk factor questionnaire (HRFQ) was distributed to each participant, followed by the performance of a fecal immunochemical test (FIT)...
September 13, 2023: International Journal of Colorectal Disease
Aiming Lv, Tianzi Gai, Sichen Zhang, Qing Feng, Ye Li
PURPOSE: This study is aimed at assessing the effect of postoperative electrical stimulation (ES) plus biofeedback therapy on patient rehabilitation after pelvic floor reconstructive surgery. METHODS: Patients with pelvic organ prolapse (POP) who had received pelvic floor reconstructive surgery were randomly allocated to the intervention group and the control group at a 1:1 ratio. Patients in the control group received routine postoperative nursing care. Patients in the intervention group underwent ES plus biofeedback therapy...
September 11, 2023: International Journal of Colorectal Disease
Sameh Hany Emile, Nir Horesh, Zoe Garoufalia, Rachel Gefen, Peige Zhou, Steven D Wexner
BACKGROUND: Current recommendations suggest that a minimum of 12 lymph nodes (LNs) should be harvested during curative rectal cancer resection. We aimed to assess predictors and survival outcomes of harvesting < 12 lymph nodes in rectal cancer surgery. METHODS: A retrospective case-control analysis of factors associated with harvesting < 12 LNs in rectal cancer surgery was conducted. Data were derived from the National Cancer Database 2010-2019...
September 9, 2023: International Journal of Colorectal Disease
E Maienza, G Godiris-Petit, S Noullet, F Menegaux, N Chereau
BACKGROUND: Postoperative adhesive small bowel obstruction (SBO) is a frequent cause of hospital admission in a surgical department. Emergency surgery is needed in a majority of patients with bowel ischemia or peritonitis; most adhesive SBO can be managed nonoperatively. Many studies have investigated benefits of using oral water-soluble contrast to manage adhesive SBO. Treatment recommendations are still controversial. METHODS: We conducted an observational retrospective monocentric study to test our protocol of management of SBO using Gastrografin® , enrolling 661 patients from January 2008 to December 2021...
September 5, 2023: International Journal of Colorectal Disease
Shahana Prakash, Tomohiro Tanaka, Divya Ashat
PURPOSE: Indeterminate colitis (IC) is subtype of colonic inflammatory bowel disease (IBD) that has features of both Crohn's disease (CD) and ulcerative colitis (UC). There have also been no studies to date examining patients hospitalized with IC in the United States (US). METHODS: We examined the demographic and clinical characteristics of patients admitted with IC and compared them with patients admitted with CD and UC. We also analyzed trends in cost and length of stay (LOS)...
August 31, 2023: International Journal of Colorectal Disease
Sabine Hannes, Maxim Kochergin, Jasmin Al-Haidary, Thorsten Götze, Nils Habbe
PURPOSE: Evaluation of the effectiveness and tolerability of the application of an OTSC (Ovesco Endoscopy AG Tuebingen, Germany) Proctology clip as an innovative strategy of anorectal fistulae closure when established treatment strategies had already failed or were not feasible. METHODS: Retrospective single-center study including consecutive patients treated between March 2014 and March 2016 with the OTSC Proctology system for anorectal fistula closure, including one rectovaginal and one rectourethral fistula...
August 30, 2023: International Journal of Colorectal Disease
Wei Liu, Xiaolong Ge, Zhaoqi Shi, Weilin Qi, Ziyao Wei, Qian Cao, Liping Cao, Wei Zhou
PURPOSE: Crohn's disease (CD) is a chronic inflammatory bowel disease that requires surgery in many cases. The aim of this article is to present the experience of a referral center regarding surgical interventions for CD, while also exploring the transformations that have occurred over 10 years. METHODS: The data of patients underwent abdominal surgery for CD between 2013 and 2022 were collected prospectively. Data were compared between two periods (2013-2017 and 2018-2022)...
August 26, 2023: International Journal of Colorectal Disease
Woo-Ri Lee, Kyu-Tae Han, Yoon Jung Chang, Seojin Park, Woorim Kim
PURPOSE: The prevalence of diabetes is higher in patients with colorectal cancer, which is important because diabetes is recognized as a risk factor for increased mortality. This study investigated the impact of incident diabetes-related complications on all-cause five-year mortality in older aged colorectal cancer patients with diabetes. METHODS: The 2008 to 2019 National Health Insurance Service data on the elderly were used to identify patients with colorectal cancer aged 60 years or above diagnosed with type 2 diabetes mellitus...
August 22, 2023: International Journal of Colorectal Disease
Ahmed Gendia, Masood Rehman, Cindy W Lin, Kamran Malik, Khalil Khalil, Ugo Ihedioha, Peter Kang, John Evans, Jamil Ahmed
PURPOSE: Abdominoperineal resection (APR) remains a key procedure for the treatment of low rectal/anorectal cancers. However, perineal wound closure remains challenging, particularly in extralevator abdominoperineal resection (ELAPR) due to gapped tissue planes. Different approaches have been attempted to improve perineal wound repair. The aim of this study is to report our 6-year experience in perineal wound closure utilising biological mesh. METHODS: We conducted a retrospective study using data from our prospectively maintained database, including patients who underwent APR with perineal mesh closure between 2016 and 2021...
August 22, 2023: International Journal of Colorectal Disease
Jens Strohäker, Martin Brüschke, You-Shan Feng, Christian Beltzer, Alfred Königsrainer, Ruth Ladurner
PURPOSE: Appendicitis is among the most common acute conditions treated by general surgery. While uncomplicated appendicitis (UA) can be treated delayed or even non-operatively, complicated appendicitis (CA) is a serious condition with possible long-term morbidity that should be managed with urgent appendectomy. Distinguishing both conditions is usually done with computed tomography. The goal of this study was to develop a model to reliably predict CA with widespread available clinical and laboratory parameters and without the use of sectional imaging...
August 19, 2023: International Journal of Colorectal Disease
Clotylde Dumas, Julie Duclos, Rémy Le Huu Nho, Magali Fermo, Emilie Gomez, Aurélia Henin, Camille Vaisse, Nicolas Pirro, Mathilde Aubert, Diane Mege
PURPOSE: To compare perioperative results of laparoscopic and robotic ventral mesh rectopexy for pelvic floor disorders at the beginning of the surgical experience. METHODS: Between 2017 and 2022, the first 30 laparoscopic ventral mesh rectopexies and the first 30 robotic ventral mesh rectopexies at the beginning of the experience of 2 surgeons were retrospectively analyzed. Perioperative (demographic characteristics, surgical indication, conversion rate, operative time), and postoperative (complications, length of stay, unplanned reintervention) data were compared between groups...
August 17, 2023: International Journal of Colorectal Disease
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