Journals International Journal of Color...

International Journal of Colorectal Disease
Fei Huang, Shan Jiang, Ran Wei, Tixian Xiao, Fangze Wei, Zhaoxu Zheng, Qian Liu
PURPOSE: Few studies have focused on anastomotic recurrence (AR) in colon cancer. This study aimed to clarify the association of resection margin distance with AR and compare the prognosis with nonanastomotic local recurrence (NAR). METHODS: This retrospective cohort study included the clinical data of patients who underwent radical colon cancer surgery between January 1, 2009, and December 31, 2019. RESULTS: A total of 1958 colon cancer patients were included in the study...
July 12, 2024: International Journal of Colorectal Disease
Sascha Vaghiri, Stephan Oliver David, Ahmad Baktash Sultani, Sami Alexander Safi, Wolfram Trudo Knoefel, Dimitrios Prassas
PURPOSE: Diverticular abscess is a common manifestation of acute complicated diverticulitis. We aimed to analyze the clinical course of patients with diverticular abscess initially treated conservatively. METHODS: All patients with diverticular abscess undergoing elective or urgent/emergency surgery from October 2004 to October 2022 were identified from our institutional database. Depending on the abscess size, patients were divided into group A (≤ 3 cm) and group B (> 3 cm)...
July 12, 2024: International Journal of Colorectal Disease
Mohammed Hamid, Omar E S Mostafa, Ali Yasen Y Mohamedahmed, Shafquat Zaman, Prajeesh Kumar, Peter Waterland, Akinfemi Akingboye
BACKGROUND: To evaluate outcomes of low with high intraabdominal pressure during laparoscopic colorectal resection surgery. METHODS: A systematic search of multiple electronic data sources was conducted, and all studies comparing low with high (standard) intraabdominal pressures were included. Our primary outcomes were post-operative ileus occurrence and return of bowel movement/flatus. The evaluated secondary outcomes included: total operative time, post-operative haemorrhage, anastomotic leak, pneumonia, surgical site infection, overall post-operative complications (categorised by Clavien-Dindo grading), and length of hospital stay...
July 10, 2024: International Journal of Colorectal Disease
Anahita Sadeghi, Ehsan Bahrami Hezaveh, Ali Ali Asgari
BACKGROUND: Sex reassignment surgery (SRS) is a necessary step in transitioning into the desired gender for male-to-female transgender individuals. This study focuses on a rare complication developed following SRS, aiming to highlight potential complications associated with this procedure. CASE PRESENTATION: This report describes a 49-year-old transgender woman with a history of SRS who developed bloody diarrhea and neovaginal bleeding 10 years later. A colonoscopy revealed features compatible with ulcerative colitis, which was confirmed by a biopsy...
July 9, 2024: International Journal of Colorectal Disease
Giuseppe S Sica, Leandro Siragusa, Brunella Maria Pirozzi, Roberto Sorge, Giorgia Baldini, Cristina Fiorani, Andrea Martina Guida, Vittoria Bellato, Marzia Franceschilli
PURPOSE: Routine use of abdominal drain or prolonged antibiotic prophylaxis is no longer part of current clinical practice in colorectal surgery. Nevertheless, in patients undergoing laparoscopic right hemicolectomy with intracorporeal anastomosis (ICA), it may reduce perioperative abdominal contamination. Furthermore, in cancer patients, prolonged surgery with extensive dissection such as central vascular ligation and complete mesocolon excision with D3 lymphadenectomy (altogether radical right colectomy RRC) is called responsible for affecting postoperative ileus...
July 6, 2024: International Journal of Colorectal Disease
Jing Mao, Yang He, Jian Chu, Boyang Hu, Yanjun Yao, Qiang Yan, Shuwen Han
BACKGROUND: Microsatellite instability (MSI) caused by DNA mismatch repair (MMR) deficiency is of great significance in the occurrence, diagnosis and treatment of colorectal cancer (CRC). AIM: This study aimed to analyze the relationship between mismatch repair status and clinical characteristics of CRC. METHODS: The histopathological results and clinical characteristics of 2029 patients who suffered from CRC and underwent surgery at two centers from 2018 to 2020 were determined...
July 5, 2024: International Journal of Colorectal Disease
Hinpetch Daungsupawong, Viroj Wiwanitkit
No abstract text is available yet for this article.
July 5, 2024: International Journal of Colorectal Disease
Hong Chen, Ji-Hong Zhang, Qin Hao, Xin-Lin Wu, Jia-Xing Guo, Cong-Xiu Huang, Jun Zhang, Guo-Sheng Xing, Zhi-Lin An, Yu Ling, Jian-Guo Zhao, Ying-Na Bao
PURPOSE: Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy or targeted therapy for those achieving a partial response (PR) offers a promising avenue to enhance treatment efficacy. This study investigated the impact of NCRT on the tumor microenvironment in locally advanced rectal cancer (LARC) patients who exhibited a PR. METHODS: This was a retrospective, observational study...
June 26, 2024: International Journal of Colorectal Disease
Hwa Ian Ong, Nastassia Shulman, Patrick Nugraha, Stephen Wrenn, Deirdre Nally, Colin Peirce, Uzma Mahmood, Jacob McCormick, David Proud, Satish Warrier, Christina Fleming, Helen Mohan
AIMS: This review aims to evaluate the feasibility of robot-assisted laparoscopic surgery (RALS) as an alternative to standard laparoscopic surgery (SLS) for the treatment of bowel deep-infiltrative endometriosis. Additionally, it aims to provide guidance for future study design, by gaining insight into the current state of research, in accordance with the IDEAL framework. METHOD: A systematic review was conducted to identify relevant studies on RALS for bowel deep infiltrating endometriosis in Medline, Embase, Cochrane Library and PubMed databases up to August 2023 and reported in keeping with PRISMA guidelines...
June 26, 2024: International Journal of Colorectal Disease
Zhen Zheng, Hui Luo, Ke Deng, Qun Li, Quan Xu, Kaitai Liu
BACKGROUND: The 8th AJCC TNM staging for non-metastatic lymph node-positive colon adenocarcinoma patients(NMLP-CA) stages solely by lymph node status, irrespective of the positivity of tumor deposits (TD). This study uses machine learning and Cox regression to predict the prognostic value of tumor deposits in NMLP-CA. METHODS: Patient data from the SEER registry (2010-2019) was used to develop CSS nomograms based on prognostic factors identified via multivariate Cox regression...
June 26, 2024: International Journal of Colorectal Disease
Francisco Cezar Aquino de Moraes, Francinny Alves Kelly, Maria Eduarda Cavalcanti Souza, Rommel Mario Rodríguez Burbano
BACKGROUND: Locally advanced rectal cancer (LARC) typically involves neoadjuvant chemoradiotherapy (nCRT) followed by surgery (total mesorectal excision, TME). While achieving a complete pathological response (pCR) is a strong indicator of a positive prognosis, the specific benefits of adjuvant chemotherapy after pCR remain unclear. To address this knowledge gap, we conducted a systematic review and meta-analysis to assess the potential advantages of adjuvant therapy in patients who achieve pCR...
June 24, 2024: International Journal of Colorectal Disease
Ya-Jie Wang, Yi-Sheng Pan
No abstract text is available yet for this article.
June 21, 2024: International Journal of Colorectal Disease
Min Hyeong Jo, Min-Jun Kim, Heung-Kwon Oh, Mi Jeong Choi, Hye-Rim Shin, Tae-Gyun Lee, Hong-Min Ahn, Duck-Woo Kim, Sung-Bum Kang
PURPOSE: To examine the ability of generative artificial intelligence (GAI) to answer patients' questions regarding colorectal cancer (CRC). METHODS: Ten clinically relevant questions about CRC were selected from top-rated hospitals' websites and patient surveys and presented to three GAI tools (Chatbot Generative Pre-Trained Transformer [GPT-4], Google Bard, and CLOVA X). Their responses were compared with answers from the CRC information book. Response evaluation was performed by two groups, each consisting of five healthcare professionals (HCP) and patients...
June 20, 2024: International Journal of Colorectal Disease
Yuan-Ling Tang, Dan-Dan Li, Jia-Yu Duan, Xin Wang
PURPOSE: The extent of tumor regression varies widely among locally advanced rectal cancer (LARC) patients who receive neoadjuvant chemoradiotherapy (NCRT) followed by total mesorectal excision (TME). The purpose of this retrospectively study is to assess prognostic factors in LARC patients with NCRT, and further to analyze survival outcomes in patients with different tumor regression grades (TRGs). METHODS: This study includes LARC patients who underwent NCRT and TME at our institution...
June 19, 2024: International Journal of Colorectal Disease
Iago Rodríguez-Lago, Marta Aduna, Patricia Ramírez de la Piscina, Olga Merino, Juan Carrascosa, Rebeca Higuera, Ainara Maíz, Eva Zapata, José Luis Cabriada, Manuel Barreiro-de Acosta
PURPOSE: Crohn's disease (CD) is a progressive disorder leading to cumulative bowel damage. The Lémann index is a validated tool that can help in monitoring the progression of the disease and evaluating the effectiveness of different therapies. Our aim was to describe the main radiological findings in incidentally diagnosed CD and to evaluate bowel damage in this subgroup compared to patients diagnosed at later stages. METHODS: Patients with an incidental diagnosis of CD during the colorectal cancer screening program were compared to controls with a CD cohort diagnosed after symptomatic onset and matched 1:1 by disease extent...
June 14, 2024: International Journal of Colorectal Disease
Beau Scaddan, Balsam Al Asedy, Samantha Lee, Parsa Rastegar Lari
PURPOSE: Surgery wait times after diagnosis of appendicitis are an important factor influencing the success of a patient's treatment. The proposed study will be a quantitative multicenter retrospective cohort design with the primary aim of assessing the difference between appendicectomy wait times between rural and urban hospitals in Western Australia and the effect of this on operative outcomes. Selected outcome measures will be examined by time from initial presentation at an emergency department to the patient being diagnosed and then time of diagnosis to surgery being performed...
June 13, 2024: International Journal of Colorectal Disease
Alexandre Carvalho, Manuel Limbert, Francisco Cabral, Ana Fareleira, Alexandre Duarte, Rita Barroca, André Goulart, Pedro Leão
INTRODUCTION: Discussions about the optimal lymph node (LN) count and its therapeutic consequences have persisted over time. The final LN count in colorectal tissues is affected by a variety of variables (patient, tumor, operation, pathologist, immune response). Methylene blue (MB) intra-arterial injection is a simple and inexpensive procedure that can be used to enhance lymph node count. AIM: Analyze whether there is a statistically significant difference between intra-arterial methylene blue injection and conventional dissection for the quantification of lymph nodes and determine if there is a variation in the quality of lymph node acquisition...
June 13, 2024: International Journal of Colorectal Disease
Kota Ouchi, Shin Takahashi, Keiju Sasaki, Yuya Yoshida, Sakura Taniguchi, Yuki Kasahara, Keigo Komine, Hiroo Imai, Ken Saijo, Hidekazu Shirota, Masanobu Takahashi, Chikashi Ishioka
PURPOSE: The genome-wide DNA methylation status (GWMS) predicts of therapeutic response to anti-epidermal growth factor receptor (EGFR) antibodies in treating metastatic colorectal cancer. We verified the significance of GWMS as a predictive factor for the efficacy of anti-EGFR antibodies in the second-line treatment of metastatic colorectal cancer. METHODS: Clinical data were obtained from a prospective trial database, and a genome-wide DNA methylation analysis was performed...
June 11, 2024: International Journal of Colorectal Disease
Hector Guadalajara, Stacye Michelle Toups, Miguel León-Arellano, Anthony Vizarreta, Damián García-Olmo
No abstract text is available yet for this article.
June 10, 2024: International Journal of Colorectal Disease
Lennard Ströse, Moritz Sparn, Marie Klein, Luca Benigno, Stephan Bischofberger, Walter Brunner
PURPOSE: Solitary fibrous tumors (SFT) are a rare entity of in majority benign neoplasms. Nevertheless, up to 20% of cases show a malignant tendency with local infiltration or metastasis. Commonly arising in the thoracic cavity, only few cases of SFT of the mesorectal tissue have been reported in the literature. Complete surgical resection, classically by posterior approach, is the treatment of choice. The purpose of this review is to demonstrate the safety and suitability of transanal minimally invasive surgery (TAMIS) as a surgical approach for the resection of benign pararectal solid tumors...
June 7, 2024: International Journal of Colorectal Disease
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.