journal

American Journal of Gastroenterology

journal
https://read.qxmd.com/read/32205646/response-to-integrating-gastrointestinal-bleeding-risk-scores-into-clinical-practice
#1
Drew Schembre
No abstract text is available yet for this article.
March 20, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32205645/proton-pump-inhibitor-use-and-risk-of-gastric-colorectal-liver-and-pancreatic-cancers-in-a-community-based-population
#2
Jeffrey K Lee, Sophie A Merchant, Jennifer L Schneider, Christopher D Jensen, Bruce H Fireman, Charles P Quesenberry, Douglas A Corley
INTRODUCTION: Proton pump inhibitors (PPIs) are commonly used for gastrointestinal disorders; given they increase the systemic levels of gastrin, a trophic hormone, there is a concern about their carcinogenicity. This study evaluated the associations PPI use and the risks of gastrointestinal cancers compared with the users. METHODS: We performed a nested case-control study in a large, community-based integrated healthcare setting. Cases were adults with gastric (n = 1,233), colorectal (n = 18,595), liver (n = 2,329), or pancreatic cancers (n = 567)...
March 20, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32205644/covid-19-disease-with-positive-fecal-and-negative-pharyngeal-and-sputum-viral-tests
#3
Lijuan Chen, Jianghua Lou, Yan Bai, Meiyun Wang
No abstract text is available yet for this article.
March 20, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32205643/recreational-marijuana-use-and-bowel-function
#4
Abhilash Perisetti, Pardeep Bansal, Hemant Goyal
No abstract text is available yet for this article.
March 20, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32205642/optimal-timing-of-feeding-after-endoscopic-hemostasis-in-patients-with-peptic-ulcer-bleeding-a-randomized-noninferiority-trial-cris-kct0001019
#5
Eun Jeong Gong, Sang Jin Lee, Baek Gyu Jun, Hyun Il Seo, Jong Kyu Park, Koon Hee Han, Young Don Kim, Woo Jin Jeong, Gab Jin Cheon, Seo Young Park
OBJECTIVES: The optimal duration of fasting after endoscopic hemostasis in patients with peptic ulcer bleeding has not yet been determined. We investigated the appropriate timing of feeding after endoscopic hemostasis in patients with high-risk peptic ulcer bleeding. METHODS: This study was a randomized, single center, noninferiority trial. Between February 2014 and March 2019, consecutive patients with peptic ulcer bleeding were randomized to resume feeding either 24 or 48 hours after successful endoscopic hemostasis...
March 20, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32205641/endoscopic-retrieval-of-a-lumen-apposing-metal-stent-that-migrated-into-the-abdominal-cavity-during-transluminal-drainage
#6
Longsong Li, Enqiang Linghu, Zantao Wang, Ningli Chai
No abstract text is available yet for this article.
March 18, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32195733/psychiatric-comorbidities-and-psychiatric-medication-use-are-highly-prevalent-in-patients-with-eosinophilic-esophagitis-and-associate-with-clinical-presentation
#7
Craig C Reed, S Ryanne Corder, Erin Kim, Emily Sanders, Manaswita Tappata, Swathi Eluri, Evan S Dellon
OBJECTIVES: The prevalence of psychiatric disease in patients with eosinophilic esophagitis (EoE) is not fully characterized. We aimed to determine the prevalence of psychiatric disease and centrally acting medication use in a cohort of children and adults with EoE and evaluated whether psychiatric disease affects the EoE clinical presentation. METHODS: We conducted a retrospective study of newly diagnosed cases with EoE at the University of North Carolina from 2002 to 2018...
March 18, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32195732/mongersen-and-smad-7-inhibition-not-a-lucky-7-for-patients-with-ibd-when-trial-design-is-as-important-as-disease-therapy
#8
Meenakshi Bewtra, Gary R Lichtenstein
The phase II mongersen (GED-0301) trial produced unparalleled success rates in Crohn's disease and generated much hope for a crippling disease. Unfortunately, the subsequent phase III trial was terminated early because of a lack of efficacy. We discuss the differences in trial design that may have contributed to these disparate findings and how these findings may serve as a lesson in subsequent therapeutic trials in Crohn's disease.
March 18, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32195731/use-of-artificial-intelligence-to-reduce-radiation-exposure-at-fluoroscopy-guided-endoscopic-procedures
#9
Ji Young Bang, Matthew Hough, Robert H Hawes, Shyam Varadarajulu
OBJECTIVES: Exposure to ionizing radiation remains a hazard for patients and healthcare providers. We evaluated the utility of an artificial intelligence (AI)-enabled fluoroscopy system to minimize radiation exposure during image-guided endoscopic procedures. METHODS: We conducted a prospective study of 100 consecutive patients who underwent fluoroscopy-guided endoscopic procedures. Patients underwent interventions using either conventional or AI-equipped fluoroscopy system that uses ultrafast collimation to limit radiation exposure to the region of interest...
March 18, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32195730/the-impact-of-the-policy-practice-gap-on-costs-and-benefits-of-barrett-s-esophagus-management
#10
Amir-Houshang Omidvari, Carlijn A M Roumans, Steffie K Naber, Sonja Kroep, Bas P L Wijnhoven, Ate van der Gaast, Pieter-Jan de Jonge, Manon C W Spaander, Iris Lansdorp-Vogelaar
INTRODUCTION: Clinical guidelines recommend surveillance of patients with Barrett's esophagus (BE). However, the surveillance intervals in practice are shorter than policy recommendations. We aimed to determine how this policy-practice gap affects the costs and benefits of BE surveillance. METHODS: We used the Netherlands as an exemplary Western country and simulated a cohort of 60-year-old patients with BE using the Microsimulation Screening Analysis model-esophageal adenocarcinoma (EAC) microsimulation model...
March 18, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32167939/ppis-and-gi-cancers-impeached-but-likely-to-be-acquitted
#11
Colin W Howden
In this edition of the journal, there is an important nested case-control study from investigators at Kaiser Permanente, Northern California. Proton pump inhibitor exposure for 10 or more years was not associated with any increased risk of gastric cancer. Small observed increased risks of colorectal, hepatocellular, and pancreatic cancers with 10 or more years of exposure are likely to have been spurious. If proton pump inhibitors were to be impeached on the basis of gastrointestinal cancer risk, they are likely to be subsequently acquitted...
March 12, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32167938/prophylactic-endoscopic-clipping-does-not-prevent-delayed-postpolypectomy-bleeding-in-routine-clinical-practice-a-propensity-score-matched-cohort-study
#12
Nauzer Forbes, Robert J Hilsden, Brendan Cord Lethebe, Courtney M Maxwell, Mubasiru Lamidi, Gilaad G Kaplan, Matthew T James, Roshan Razik, Lawrence C Hookey, William A Ghali, Michael J Bourke, Steven J Heitman
OBJECTIVES: Delayed postpolypectomy bleeding (DPPB) is a relatively common adverse event. Evidence is conflicting on the efficacy of prophylactic clipping to prevent DPPB, and real-world effectiveness data are lacking. We aimed to determine the effectiveness of prophylactic clipping in preventing DPPB in a large screening-related cohort. METHODS: We manually reviewed records of patients who underwent polypectomy from 2008 to 2014 at a screening facility. Endoscopist-, patient- and polyp-related data were collected...
March 12, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32167937/endoscopic-ultrasound-guided-gastrojejunostomy-for-the-management-of-superior-mesenteric-artery-syndrome
#13
Zain A Sobani, Tarun Rustagi
No abstract text is available yet for this article.
March 12, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32149781/positive-hepatitis-b-core-antibody-is-associated-with-cirrhosis-and-hepatocellular-carcinoma-in-nonalcoholic-fatty-liver-disease
#14
Ting Ting Chan, Wah Kheong Chan, Grace Lai-Hung Wong, Anthony Wing-Hung Chan, Nik Raihan Nik Mustapha, Stephen Lam Chan, Charing Ching-Ning Chong, Sanjiv Mahadeva, Sally She-Ting Shu, Paul Bo-San Lai, Henry Lik-Yuen Chan, Vincent Wai-Sun Wong
OBJECTIVES: Previous exposure to hepatitis B virus (HBV) may increase the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C. We aim to study the impact of previous HBV infection on the severity and outcomes of patients with nonalcoholic fatty liver disease (NAFLD). METHODS: This was a multicenter study of 489 patients with biopsy-proven NAFLD and 69 patients with NAFLD-related or cryptogenic HCC. Antihepatitis B core antibody (anti-HBc) was used to detect the previous HBV infection...
March 9, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32149780/incidence-of-and-risk-factors-for-systemic-adverse-events-after-screening-or-primary-diagnostic-colonoscopy-a-nationwide-cohort-study
#15
Moussa Laanani, Alain Weill, Franck Carbonnel, Jacques Pouchot, Joël Coste
OBJECTIVES: To estimate the systemic serious adverse event (SAE) rates after colonoscopy and to identify their risk factors. METHODS: A nationwide cohort study was conducted using the comprehensive French claims databases SNDS (National Health Data System). Patients aged 30 years and over who underwent a first screening or diagnostic colonoscopy in 2010-2015 were included. The rates of cardiovascular and renal SAEs were estimated within 5 days after colonoscopy...
March 6, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32149779/response-to-sullivan-et-al
#16
Fateh Bazerbachi, Eric J Vargas, Barham K Abu Dayyeh
No abstract text is available yet for this article.
March 6, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32149778/successful-therapy-of-crohn-s-disease-associated-pulmonary-necrobiotic-nodules-on-ustekinumab-therapy
#17
Ingo Ganzleben, Simon Hirschmann, Julia Köhler, Florian S Fuchs, Ralf J Rieker, Eva Baer, Entcho Klenske, Daniel Nagore, Markus F Neurath, Raja Atreya
No abstract text is available yet for this article.
March 6, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32141913/correction-low-prevalence-of-helicobacter-pylori-positive-peptic-ulcers-in-private-outpatient-endoscopy-centers-in-the-united-states
#18
Amnon Sonnenberg, Kevin O Turner, Robert M Genta
No abstract text is available yet for this article.
March 5, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32141915/management-of-small-bowel-villous-atrophy-in-patients-seronegative-for-celiac-disease
#19
Claire L Jansson-Knodell, Joseph A Murray, Alberto Rubio-Tapia
No abstract text is available yet for this article.
March 4, 2020: American Journal of Gastroenterology
https://read.qxmd.com/read/32141914/association-between-proton-pump-inhibitors-use-and-dementia-risk
#20
Shih-Wei Lai, Kuan-Fu Liao
No abstract text is available yet for this article.
March 4, 2020: American Journal of Gastroenterology
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