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Journals American Journal of Gastroente...

American Journal of Gastroenterology

https://read.qxmd.com/read/38606843/antibiotic-prophylaxis-for-ercp
#1
JOURNAL ARTICLE
Shyam Menon
No abstract text is available yet for this article.
April 12, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38602347/underwater-endoscopic-mucosal-resection-for-superficial-nonampullary-duodenal-epithelial-tumors
#2
JOURNAL ARTICLE
Avinash Tiwari, Malay Sharma
No abstract text is available yet for this article.
April 11, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38595149/central-neuromodulators-in-irritable-bowel-syndrome-why-how-and-when
#3
JOURNAL ARTICLE
Ignacio Hanna-Jairala, Douglas A Drossman
Irritable bowel syndrome are responsive to treatments using central neuromodulators. Central neuromodulators work by enhancing the synaptic transmission of 5-hydroxytryptamine, noradrenalin and dopamine, achieving a slower regulation or desensitization of their postsynaptic receptors. Central neuromodulators act on receptors along the brain-gut axis, so they are useful in treating psychiatric comorbidities, modifying gut motility, improving central downregulation of visceral signals and enhancing neurogenesis in patients with IBS...
April 9, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38587293/high-concordance-between-nonalcoholic-fatty-liver-disease-and-metabolic-dysfunction-associated-steatotic-liver-disease-in-the-target-nash-real-world-cohort
#4
JOURNAL ARTICLE
A Sidney Barritt, Feng Yu, Andrea R Mospan, Philip Newsome, Michael Roden, Heather L Morris, Rohit Loomba, Brent A Neuschwander-Tetri
INTRODUCTION: This study investigates the applicability of the new MASLD nomenclature to the real-world TARGET-NASH US adult cohort. METHODS: The new MASLD/MASH nomenclature was applied to patients enrolled with pragmatic diagnoses of NAFL, NASH and NASH cirrhosis and concordance was determined between the definitions. RESULTS: 99% of TARGET-NASH participants met the new MASLD diagnostic criteria. 1484/1541 (96.3%, kappa 0.974) NAFL patients (MASL), 2195/2201 (99...
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38587292/the-role-of-the-gastroenterologist-in-obesity-management-now-is-the-right-time-for-our-involvement
#5
JOURNAL ARTICLE
Stephanie L Gold, Asher Kornbluth
No abstract text is available yet for this article.
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38587288/metabolic-sequelae-and-all-cause-mortality-in-chronic-pancreatitis-with-and-without-prior-acute-pancreatitis-a-nationwide-population-based-cohort-study
#6
JOURNAL ARTICLE
Mathias Ellgaard Cook, Niels Henrik Bruun, Line Davidsen, Peter Vestergaard, Asbjørn Mohr Drewes, Søren Schou Olesen
OBJECTIVES: To investigate the risk of metabolic sequelae and all-cause mortality in a population-based cohort of chronic pancreatitis (CP) patients with and without prior acute pancreatitis (AP). METHODS: We used nationwide health registries to identify all Danish residents (>18 years) with incident CP from 2000-2018. Information on AP/CP diagnoses, metabolic sequelae (post-pancreatitis diabetes mellitus (PPDM), exocrine pancreatic dysfunction (EPD), and osteoporosis), and all-cause mortality were obtained from Danish national health registries...
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38587287/overt-hepatic-encephalopathy-more-than-meets-the-eye
#7
JOURNAL ARTICLE
Davide Erminelli, Chiara Mangini, Lisa Zarantonello, Paolo Angeli, Sara Montagnese
INTRODUCTION: To assess the reliability of a qualitative approach to overt hepatic encephalopathy (OHE) diagnosis compared to the semi-quantitative, recommended one. METHODS: The above two methods were compared in 411 outpatients (71% males, 60±10 years, MELD 13.5±5.0). RESULTS: Of the 73 patients with OHE on quantitative assessment, 19 (26%) were missed on qualitative assessment, with no difference in the likelihood of the physician missing grades II or III...
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38587286/associations-of-intra-pancreatic-fat-deposition-with-incident-diseases-of-the-exocrine-and-endocrine-pancreas-a-uk-biobank-prospective-cohort-study
#8
JOURNAL ARTICLE
Xiaowu Dong, Qingtian Zhu, Chenchen Yuan, Yaodong Wang, Xiaojie Ma, Xiaolei Shi, Weiwei Chen, Zhao Dong, Lin Chen, Qinhao Shen, Hongwei Xu, Yanbing Ding, Weijuan Gong, Weiming Xiao, Shengfeng Wang, Weiqin Li, Guotao Lu
OBJECTIVE: Investigate whether increased IPFD heightens the risk of diseases of the exocrine and endocrine pancreas. METHODS: A prospective cohort study was conducted using data from the UK Biobank. IPFD was quantified using MRI and a deep learning-based framework called nnUNet. The prevalence of fatty change of the pancreas (FP) was determined using gender- and age-specific thresholds. Associations between IPFD and pancreatic diseases were assessed with multivariate Cox proportional hazard model adjusted for age, sex, ethnicity, body mass index, smoking and drinking status, central obesity, hypertension, dyslipidemia, liver fat content, and spleen fat content...
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38587284/asymptomatic-colonic-anisakis-infiltrating-a-post-endoscopic-mucosal-resection-scar
#9
JOURNAL ARTICLE
Kazuya Sumi, Akira Ishihara, Haruhiro Inoue
No abstract text is available yet for this article.
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38587280/rates-of-recurrent-intestinal-metaplasia-and-dysplasia-after-successful-endoscopic-therapy-of-barrett-s-neoplasia-by-emr-vs-esd-and-ablation-a-large-north-american-multicenter-cohort
#10
JOURNAL ARTICLE
Kornpong Vantanasiri, Abel Joseph, Karan Sachdeva, Rohit Goyal, Nikita Garg, Dayyan Adoor, Amrit K Kamboj, D Chamil Codipilly, Cadman Leggett, Kenneth K Wang, William Harmsen, Umar Hayat, Amitabh Chak, Amit Bhatt, Prasad G Iyer
BACKGROUND: Endoscopic eradication therapy (EET) combining endoscopic resection (ER) with endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) followed by ablation is the standard of care for the treatment of dysplastic Barrett's esophagus (BE). We have previously shown comparable rates of complete remission of intestinal metaplasia (CRIM) with both approaches. However, data comparing recurrence after CRIM are lacking. We compared rates of recurrence after CRIM with both techniques in a multicenter cohort...
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38578969/characterization-of-the-small-bowel-microbiome-reveals-different-profiles-in-human-subjects-who-are-overweight-or-have-obesity
#11
JOURNAL ARTICLE
Gabriela Leite, Gillian M Barlow, Mohamad Rashid, Ava Hosseini, Daniel Cohrs, Gonzalo Parodi, Walter Morales, Stacy Weitsman, Ali Rezaie, Mark Pimentel, Ruchi Mathur
OBJECTIVES: Gut microbiome changes are linked to obesity, but findings are based on stool data. Here, we analyzed the duodenal microbiome and serum biomarkers in subjects with normal weight, overweight, and obesity. METHODS: Duodenal aspirates and serum samples were obtained from subjects undergoing standard-of-care esophagogastroduodenoscopy without colon preparation. Aspirate DNAs were analyzed by 16S rRNA and shotgun sequencing. Predicted microbial metabolic functions and serum levels of metabolic and inflammatory biomarkers were also assessed...
April 8, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38557790/scratch-beneath-the-surface-unexpected-colonic-perforation
#12
JOURNAL ARTICLE
Andreia Rei, Sara Archer, Luísa Brochado-Ferreira, Isabel Pedroto, Ricardo Küttner-Magalhães
No abstract text is available yet for this article.
April 2, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38546128/somatic-mutational-analysis-in-eus-guided-biopsy-of-pancreatic-adenocarcinoma-assessing-yield-and-impact
#13
JOURNAL ARTICLE
Sue Dong, Emil Agarunov, Matthew Fasullo, Ki-Yoon Kim, Lauren Khanna, Gregory Haber, Eileen Janec, Diane Simeone, Paul Oberstein, Tamas Gonda
OBJECTIVES: We sought to determine the yield of somatic mutational analysis from EUS-guided biopsies of pancreatic adenocarcinoma compared to that of surgical resection and to assess the impact of these results on oncologic treatment. METHODS: We determined the yield of EUS sampling and surgical resection. We evaluated the potential impact of mutational analysis by identifying actionable mutations and its direct impact by reviewing actual treatment decisions. RESULTS: Yield of EUS sampling was 89...
March 28, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38546124/bleeding-gastric-polyps-a-rare-presentation-of-renal-cell-carcinoma-metastasis
#14
JOURNAL ARTICLE
Reid Schalet, Adam M Jacob, Alessandro El Khoury, Marie L Borum, Mamoun Younes, Sumona Bhattacharya
No abstract text is available yet for this article.
March 28, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38372280/role-of-the-intestine-and-its-gut-microbiota-in-metabolic-syndrome-and-obesity
#15
JOURNAL ARTICLE
Celine B E Busch, Jacques J G H M Bergman, Max Nieuwdorp, Annieke C G van Baar
The metabolic syndrome (MetSyn) is currently one of the biggest global health challenges because of its impact on public health. MetSyn includes the cluster of metabolic disorders including obesity, high blood pressure, hyperglycemia, high triglyceride levels, and hepatic steatosis. Together, these abnormalities increase the cardiovascular risk of individuals and pose a threat to healthcare systems worldwide. To better understand and address this complex issue, recent research has been increasingly focusing on unraveling the delicate interplay between metabolic disorders and the intestines and more specifically our gut microbiome...
March 28, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38534172/low-grade-appendiceal-mucinous-neoplasm-a-subtle-presentation-during-colonoscopy
#16
JOURNAL ARTICLE
Erin M Tonzi, Byron F Santos-Aleman, David A Klibansky
No abstract text is available yet for this article.
March 27, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38534167/the-impact-of-weight-loss-programs-on-bmi-trajectory-in-patients-with-metabolic-dysfunction-associated-steatotic-liver-disease-a-veterans-health-administration-study
#17
JOURNAL ARTICLE
Helen Tang, David E Kaplan, Nadim Mahmud
BACKGROUND: Weight loss is the mainstay of management for patients with metabolic dysfunction-associated steatotic liver disease. We studied the impact of referral to MOVE!, a nationally-implemented behavioral weight loss program, on weight in MASLD patients. METHODS: This retrospective cohort study included 102,294 MASLD patients from 125 Veterans Health Administration centers from 2008-2022. RESULTS: Most patients lost no significant weight or gained weight...
March 27, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38534166/early-gastric-signet-ring-cell-adenocarcinoma-as-a-flat-pale-patch-on-an-esophagogastroduodenoscopy
#18
JOURNAL ARTICLE
Will Takakura, Shanti Eswaran, William D Chey, Hiroya Ueyama, Richard Kwon, Andrea Todisco, Scott Owens, Elena Stoffel, Oxana V Crysler, Filip Bednar, Benjamin R Hart
No abstract text is available yet for this article.
March 27, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38534155/long-term-risks-for-cirrhosis-and-hepatocellular-carcinoma-across-steatotic-liver-disease-subtypes
#19
JOURNAL ARTICLE
Yi-Ting Chen, Tzu-I Chen, Tsai-Hsuan Yang, Szu-Ching Yin, Sheng-Nan Lu, Xia-Rong Liu, Yun-Zheng Gao, Chih-Jo Lin, Chia-Wei Huang, Jee-Fu Huang, Ming-Lun Yeh, Chung-Feng Huang, Chia-Yen Dai, Wan-Long Chuang, Hwai-I Yang, Ming-Lung Yu, Mei-Hsuan Lee
INTRODUCTION: The prospective study aimed to investigate the long-term associated risks of cirrhosis and hepatocellular carcinoma (HCC) across various subtypes of steatotic liver disease (SLD). METHODS: We enrolled 332,175 adults who participated in a health screening program between 1997 and 2013. Participants were categorized into various subtypes, including metabolic dysfunction-associated steatotic liver disease (MASLD), MASLD with excessive alcohol consumption (MetALD), and alcohol-related liver disease (ALD), based on ultrasonography findings, alcohol consumption patterns, and cardiometabolic risk factors...
March 27, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38534140/an-uncommon-case-of-a-not-so-microscopic-colitis
#20
JOURNAL ARTICLE
Karolina Krawczyk, Amanda Siegel
No abstract text is available yet for this article.
March 27, 2024: American Journal of Gastroenterology
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