journal

American Journal of Gastroenterology

journal
https://read.qxmd.com/read/31693505/linear-immunoglobulin-a-bullous-dermatosis-associated-with-ulcerative-colitis
#1
Shruti Agrawal, Urmi Khanna, Anthony P Fernandez, Mahwish Irfan, Joshua Arbesman
No abstract text is available yet for this article.
November 6, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31688023/lactulose-breath-testing-as-a-predictor-of-response-to-rifaximin-in-patients-with-irritable-bowel-syndrome-with-diarrhea
#2
Ali Rezaie, Zeev Heimanson, Richard McCallum, Mark Pimentel
OBJECTIVES: The nonsystemic antibiotic rifaximin is indicated for irritable bowel syndrome with diarrhea (IBS-D) in adults; however, determinants of response remain unclear. The utility of lactulose breath testing (LBT) in predicting response to rifaximin was examined. METHODS: Adults with IBS-D received open-label rifaximin 550 mg 3 times daily for 2 weeks, followed by a 4-week posttreatment assessment period. Thirteen centers prospectively participated in this substudy...
November 1, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31687980/diagnosis-and-care-of-anorectal-issues-should-be-included-in-the-gastrointestinal-fellowship-training-program-curriculum
#3
Waqar Qureshi
No abstract text is available yet for this article.
November 1, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31688022/early-paracentesis-in-high-risk-hospitalized-patients-time-for-a-new-quality-indicator
#4
Russell Rosenblatt, Zaid Tafesh, Nicole Shen, Shirley Cohen-Mekelburg, Sonal Kumar, Catherine Lucero, Robert S Brown, Elizabeth Verna, Brett Fortune, Arun Jesudian
INTRODUCTION: Symptomatic ascites is the most common indication for hospitalization in patients with cirrhosis. Although guidelines recommend paracentesis for all inpatients with ascites, the timing of paracentesis is likely to be crucial. Performance of an early paracentesis and its relationship to outcomes are unknown, particularly among patients at high risk of spontaneous bacterial peritonitis (SBP). METHODS: We included 75,462 discharges of adult patients with cirrhosis presenting with ascites who underwent paracentesis from the State Inpatient Databases of New York, Florida, and Washington from 2009 to 2013...
October 31, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31688021/rising-mortality-from-alcohol-associated-liver-disease-in-the-united-states-in-the-21st-century
#5
Andrew M Moon, Jeff Y Yang, A Sidney Barritt, Ramon Bataller, Anne F Peery
OBJECTIVES: In contrast with other developed nations, life expectancy is decreasing in the United States, in part due to increasing mortality from alcohol-associated liver disease (ALD). Up-to-date estimates of ALD mortality are necessary for setting public health priorities to reverse this concerning trend. We therefore aimed to assess current (2017) estimates of ALD mortality and temporal trends from 1999 to 2017. METHODS: Using national data from the Centers for Disease Control and Prevention, we analyzed stratified ALD mortality rates between 1999 and 2017...
October 31, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31688024/type-2-diabetes-prevention-diet-and-hepatocellular-carcinoma-risk-in-us-men-and-women
#6
Xiao Luo, Jing Sui, Wanshui Yang, Qi Sun, Yanan Ma, Tracey G Simon, Geyu Liang, Jeffrey A Meyerhardt, Andrew T Chan, Edward L Giovannucci, Xuehong Zhang
OBJECTIVES: Adherence to a healthy diet has been associated with a reduced risk of type 2 diabetes (T2D). Hepatocellular carcinoma (HCC) may have overlapping mechanisms with T2D, such as inflammation and insulin resistance. Thus, we examined the association between a previously developed T2D prevention dietary pattern and HCC risk. METHODS: We followed 87,943 women in the Nurses' Health Study and 49,665 men in the Health Professionals Follow-up Study for up to 32 years...
October 30, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658124/helicobacter-pylori-when-we-should-treat%C3%A2
#7
William D Chey
No abstract text is available yet for this article.
October 25, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658123/circulating-sex-hormone-levels-and-risk-of-esophageal-adenocarcinoma-in-a-prospective-study-in-men
#8
Shao-Hua Xie, Eivind Ness-Jensen, Sirus Rabbani, Hilde Langseth, Randi E Gislefoss, Fredrik Mattsson, Jesper Lagergren
OBJECTIVES: Sex hormones have been hypothesized to explain the strong male predominance in esophageal adenocarcinoma, but evidence is needed. This study examined how circulating sex hormone levels influence future risk of esophageal adenocarcinoma. METHODS: This case-control study was nested in a prospective Norwegian cohort (Janus Serum Bank Cohort), including 244 male patients with esophageal adenocarcinoma and 244 male age-matched control participants. Associations between prediagnostic circulating levels of 12 sex hormones and risk of esophageal adenocarcinoma were assessed using conditional logistic regression...
October 25, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658122/increased-risk-of-osteoporotic-fracture-in-postgastrectomy-gastric-cancer-survivors-compared-with-matched-controls-a-nationwide-cohort-study-in-korea
#9
Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Yun-Suhk Suh, Yoon Jin Choi, Su-Min Jeong, Jae Moon Yun, Sun Ok Song, Youngmin Park
OBJECTIVES: Gastrectomy can lead to bone loss. Previous studies have suggested that there is an increased risk of fracture in gastric cancer survivors. However, these studies were performed without proper control groups. Therefore, we used Korean national health insurance data to compare the fracture risk in gastric cancer survivors who received gastrectomy to that of the general population. METHODS: A total of 133,179 gastric cancer survivors were included and matched to noncancer controls using 1:1 propensity score matching...
October 25, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658121/jejunum-hemolymphangioma-causing-refractory-anemia-in-a-young-woman
#10
Jingze Yang, Yan Zhang, Guanjun Kou, Yanqing Li
No abstract text is available yet for this article.
October 25, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658128/endoscopic-sleeve-gastroplasty-in-109-consecutive-children-and-adolescents-with-obesity-two-year-outcomes-of-a-new-modality
#11
Aayed Alqahtani, Mohamed Elahmedi, Yara A Alqahtani, Abdullah Al-Darwish
OBJECTIVES: Endoscopic sleeve gastroplasty (ESG) uses full-thickness sutures that restrict the stomach to a sleeve-like configuration. There is no published evidence on endoscopic tissue apposition techniques in pediatric patients. In this article, we report our ESG experience with the first 109 pediatric patients with obesity who underwent ESG under our care. METHODS: ESG was offered as a day-case procedure under a standardized protocol and clinical pathway that included surgical, medical, and endoscopic modalities for the treatment of pediatric and adult obesity...
October 24, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658127/phase-transition-is-infrequent-among-north-american-adults-with-e-antigen-negative-chronic-hepatitis-b-and-low-level-viremia
#12
Kali Zhou, Abdus S Wahed, Stewart Cooper, Adrian M Di Bisceglie, Robert J Fontana, Marc G Ghany, Mandana Khalili, Anna S Lok, Robert Perrillo, William M Lee, Daryl T Y Lau, Richard Sterling, Harry L A Janssen, Norah A Terrault
INTRODUCTION: Patients with hepatitis B early antigen (HBeAg)-negative chronic hepatitis B (CHB) and low-level viremia are a heterogeneous group. Identifying those at risk of developing active CHB requiring antiviral therapy is important. In this study, we prospectively characterize incidence rates and predictors of transitioning from inactive to active CHB in a North American adult cohort. METHODS: Participants in the multicenter National Institute of Diabetes and Digestive and Kidney Diseases Hepatitis B Research Network cohort who were HBeAg negative with baseline hepatitis B virus (HBV) DNA ≤ 10,000 IU/mL were included in the study...
October 24, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658126/gastrocolic-fistula-involving-the-pancreas-in-a-patient-with-crohn-s-disease
#13
Alexander T Booth, Erin Forster, Thomas Curran, Virgilio George
No abstract text is available yet for this article.
October 24, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658125/yield-and-practice-patterns-of-surveillance-colonoscopy-among-older-adults-an-analysis-of-the-gi-quality-improvement-consortium
#14
Audrey H Calderwood, Jennifer L Holub, David A Greenwald, Douglas J Robertson
OBJECTIVES: There is little guidance regarding when to stop surveillance colonoscopy in individuals with a history of adenomas or colorectal cancer (CRC). We evaluated both yield and recommendations for follow-up colonoscopy in a large cohort of older individuals undergoing colonoscopy, using the GI Quality Improvement Consortium registry. METHODS: We analyzed the yield of colonoscopy in adults aged ≥75 years, comparing those who had an indication of surveillance as opposed to an indication of diagnostic or screening, stratified by 5-year age groups...
October 24, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31651445/esophageal-sinus-in-a-patient-with-antineutrophil-cytoplasmic-antibody-associated-vasculitis
#15
Rongqian Chen, Xinjuan Liu, Jianyu Hao
No abstract text is available yet for this article.
October 23, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31651444/prediction-of-polyp-pathology-using-convolutional-neural-networks-achieves-resect-and-discard-thresholds
#16
Robin Zachariah, Jason Samarasena, Daniel Luba, Erica Duh, Tyler Dao, James Requa, Andrew Ninh, William Karnes
OBJECTIVES: Reliable in situ diagnosis of diminutive (≤5 mm) colorectal polyps could allow for "resect and discard" and "diagnose and leave" strategies, resulting in $1 billion cost savings per year in the United States alone. Current methodologies have failed to consistently meet the Preservation and Incorporation of Valuable endoscopic Innovations (PIVIs) initiative thresholds. Convolutional neural networks (CNNs) have the potential to predict polyp pathology and achieve PIVI thresholds in real time...
October 23, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31651443/recurrent-hematochezia-and-hemoptysis-due-to-colon-pulmonary-fistula
#17
Zhong-Yi Qin, Xiao Xiao, Bin Wang
No abstract text is available yet for this article.
October 23, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31651442/severe-achalasia-causing-cor-pulmonale
#18
Mahmoud Bayoumi, Allon Kahn, Diana L Snyder, Christine O Menias, Mareclo F Vela
No abstract text is available yet for this article.
October 23, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658130/overestimated-sensitivity-of-fecal-immunochemical-tests-in-screening-cohorts-with-registry-based-follow-up
#19
Hermann Brenner, Anton Gies, Kevin Selby
OBJECTIVES: Several recent studies have reported very high estimates of sensitivity and specificity of fecal immunochemical tests (FITs) at seemingly high levels of precision using registry-based follow-up of participants in very large FIT-based screening programs. We aimed to assess the validity of estimates of diagnostic performance parameters derived by this indirect approach. METHODS: We modeled expected values of sensitivity and specificity of colorectal cancer detection in studies using the indirect approach and their deviation from true values under a broad range of plausible assumptions, and we compared these expected values with recently reported estimates of FIT sensitivity and specificity from such studies...
October 21, 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/31658129/delayed-gastric-emptying-associates-with-diabetic-complications-in-diabetic-patients-with-symptoms-of-gastroparesis
#20
Henry P Parkman, Laura A Wilson, Gianrico Farrugia, Kenneth L Koch, William L Hasler, Linda A Nguyen, Thomas L Abell, William Snape, John Clarke, Braden Kuo, Richard W McCallum, Irene Sarosiek, Madhusudan Grover, Laura Miriel, James Tonascia, Frank A Hamilton, Pankaj J Pasricha
OBJECTIVES: Diabetic gastroparesis (Gp) occurs more often in type 1 diabetes mellitus (T1DM) than in type 2 diabetes mellitus (T2DM). Other diabetic end-organ complications include peripheral neuropathy, nephropathy, and retinopathy (together termed triopathy). This study determines the prevalence of diabetic complications (retinopathy, nephropathy, and peripheral neuropathy) in diabetic patients with symptoms of Gp, assessing the differences between T1DM and T2DM and delayed and normal gastric emptying (GE)...
October 21, 2019: American Journal of Gastroenterology
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