Journals American Journal of Gastroente...

American Journal of Gastroenterology
Matteo Ghisa, Ilenia Barbuscio, Brigida Barberio, Edoardo Savarino
No abstract text is available yet for this article.
February 19, 2021: American Journal of Gastroenterology
Christina Ha
This editorial comments on the study by Khan et al. that describes potential risk of acute myeloid leukemia or myeloproliferative disorder among thiopurine therapy.
February 18, 2021: American Journal of Gastroenterology
Xing Su, Qin He, Yuxia Zhu, Peng Zou, Mingke Li, Ruizheng Zou
No abstract text is available yet for this article.
February 18, 2021: American Journal of Gastroenterology
Giulia Tosetti, Elisabetta Degasperi, Elisa Farina, Roberta D'Ambrosio, Roberta Soffredini, Marta Borghi, Vincenzo La Mura, Massimo Primignani, Pietro Lampertico
Nonselective β-blockers improve decompensation-free survival in viremic hepatitis C virus compensated cirrhotic patients with clinically significant portal hypertension, but their protective role after sustained virological response by direct-acting antiviral (DAA) is undefined. We evaluated the incidence of decompensation in DAA-cured Child-A patients without high-risk varices. During the 49-month (12-60) follow-up, only one of 148 patients decompensated (ascites), with a 4-year cumulative risk of 1%, but decompensation was associated with hepatocellular carcinoma...
February 18, 2021: American Journal of Gastroenterology
Cary Kraft, Rebecca Greaves Kim, Priya Kathpalia
No abstract text is available yet for this article.
February 18, 2021: American Journal of Gastroenterology
Suneela Vegunta, Amit A Shah, M Helen Whited, Margaret E Long
Anal cancer is rare in the general population but is steadily increasing in incidence over the past decade especially in women. Identification and screening of women with high risk facilitates detection of anal precancer and early-stage cancer, improves survival, and potentially uses less invasive therapies compared with the conventional chemoradiation treatments used for advanced cancers. No recently published guidelines currently describe details about screening women for anal squamous cell cancer (ASCC)...
February 18, 2021: American Journal of Gastroenterology
Britt B S L Houwen, Nahid Mostafavi, Jasper L A Vleugels, Robert Hüneburg, Christof Lamberti, Liseth Rivero-Sánchez, María Pellisé, Elena M Stoffel, Sapna Syngal, Jasmijn F Haanstra, Jan J Koornstra, Evelien Dekker, Yark Hazewinkel
INTRODUCTION: The additional diagnostic value of dye-based chromoendosocpy (CE) for surveillance of patients with Lynch syndrome is subject of debate. METHODS: To clarify this debate, we performed an individual patient data meta-analysis of randomized studies that compared CE with WLE for the detection of adenomas in patients with Lynch syndrome. RESULTS: Three randomized studies comprising 533 patients were included. The adenoma detection rate was 74/265 (28%) in patients randomized to WLE compared with 83/266 (31%) in patients randomized to CE (odds ratio 1...
February 11, 2021: American Journal of Gastroenterology
Neal Shahidi, Sergei Vosko, Sunil Gupta, W Arnout van Hattem, Mayenaaz Sidhu, David J Tate, Stephen J Williams, Eric Y T Lee, Nicholas Burgess, Michael J Bourke
INTRODUCTION: Endoscopic mucosal resection (EMR) is an effective therapy for naive large nonpedunculated colorectal polyps (N-LNPCPs). The best approach for the treatment of previously attempted LNPCPs (PA-LNPCPs) is undetermined. METHODS: EMR performance for PA-LNPCPs was evaluated in a prospective observational cohort of LNPCPs ≥20 mm. Efficacy was measured by technical success (removal of all visible polypoid tissue during index EMR) and recurrence at first surveillance colonoscopy (SC1)...
February 9, 2021: American Journal of Gastroenterology
Jeffrey Mather
No abstract text is available yet for this article.
February 9, 2021: American Journal of Gastroenterology
Monika Laszkowska, Steven Rodriguez, Judith Kim, Chin Hur
INTRODUCTION: Evidence regarding the association between alcohol use and gastric cancer (GC) has been inconsistent. METHODS: Adults who participated in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2010 were included. Multivariable regression was used to assess the association between GC and heavy alcohol use (≥5 alcoholic drinks daily). RESULTS: Of 470,168 individuals surveyed, 342 had a history of GC. Heavy alcohol use was associated with GC (odds ratio 3...
February 9, 2021: American Journal of Gastroenterology
Sanchit Gupta, Benjamin H Mullish, Jessica R Allegretti
Fecal microbiota transplantation (FMT) has been recommended in clinical guidelines for the treatment of recurrent Clostridioides difficile infection (CDI). However, it is considered investigational by most regulatory agencies. As the adoption of FMT has increased from a small group of CDI experts alone to more widespread use, there has been a corresponding increase in concern regarding potential risk. FMT is largely considered a safe procedure although risks described range from mild gastrointestinal symptoms to serious infection...
February 5, 2021: American Journal of Gastroenterology
Meaghan Phipps, Julia Wattacheril
No abstract text is available yet for this article.
February 3, 2021: American Journal of Gastroenterology
Sagar Joshi, Joel H Rubenstein, Evan S Dellon, Nathan Worthing, Zoe Stefanadis, Joy W Chang
INTRODUCTION: Little is known about the use of compounded steroids for eosinophilic esophagitis (EoE). METHODS: We conducted a telephone survey of all compounding pharmacies in Michigan and queried about practices and costs of compounded budesonide for EoE. RESULTS: Of 68 Michigan pharmacies, 93% responded, and 20 (29%) offer compounded budesonide suspension for EoE. Formulations, dose, and instructions for use varied across pharmacies. The mean cost for a 30-day supply was $74...
February 3, 2021: American Journal of Gastroenterology
Ângelo Zambam de Mattos, Gabriel Stefani Leão, Isadora Zanotelli Bombassaro, Talita Chiesa, Angelo Alves de Mattos
No abstract text is available yet for this article.
January 29, 2021: American Journal of Gastroenterology
Melis G Celdir, Rok Seon Choung, Shahryar K Rostamkolaei, Claire L Jansson-Knodell, Katherine S King, Joseph J Larson, Imad Absah, Joseph A Murray
INTRODUCTION: Untreated symptomatic celiac disease (CD) adversely affects female reproduction; however, the effect of hidden CD autoimmunity is uncertain. METHODS: We identified women who were not previously diagnosed with CD and tested positive for tissue transglutaminase and endomysial antibodies between 2006 and 2011 in a community-based retrospective cohort study. We evaluated (i) the rate of adverse pregnancy outcomes and medical complications of pregnancy in successful singleton deliveries and (ii) reproductive characteristics in seropositive women without a clinical diagnosis of CD and age-matched seronegative women...
January 29, 2021: American Journal of Gastroenterology
Tetsuya Suwa, Kenichiro Imai, Kinichi Hotta, Sayo Ito, Yoshihiro Kishida, Hiroyuki Ono
No abstract text is available yet for this article.
January 28, 2021: American Journal of Gastroenterology
Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Vicki Wing-Ki Hui, Terry Cheuk-Fung Yip, Yee-Kit Tse, Lilian Yan Liang, Rashid Nok-Shun Lui, Tony Shu-Kam Mok, Henry Lik-Yuen Chan, Stephen Lam Chan
INTRODUCTION: Immunotherapy has dramatically improved the survival of patients with advanced or metastatic malignancies. Recent studies suggest that immunotherapy may increase the risk of hepatitis, whereas it may also induce functional cure of chronic hepatitis B virus (HBV) infection. We evaluated the incidence of hepatitis flare, HBV reactivation, hepatitis B surface antigen (HBsAg) seroclearance or seroreversion in patients with current or past HBV infection who had received immunotherapy...
January 28, 2021: American Journal of Gastroenterology
Swati Pawa, Promila Banerjee, Shivangi Kothari, Sharlene L D'Souza, Sarah L Martindale, Jill K J Gaidos, Amy S Oxentenko, Carol A Burke
INTRODUCTION: Endoscopy-related injury (ERI) is common in gastroenterologists (GI). The study aim was to assess the prevalence of self-reported ERI, patterns of injury, and endoscopist knowledge of preventative strategies in a nationally representative sample. METHODS: A 38-item electronic survey was sent to 15,868 American College of Gastroenterology physician members. The survey was completed by 1,698 members and was included in analyses. Descriptive, univariate, and multivariate analyses were conducted to evaluate the likelihood of ERI based on workload parameters and gender...
January 28, 2021: American Journal of Gastroenterology
Jason R Baker, William D Chey, Lydia Watts, Moira Armstrong, Kristen Collins, Allen A Lee, Ajith Dupati, Stacy Menees, Richard J Saad, Kimberly Harer, William L Hasler
INTRODUCTION: The North American Consensus guidelines for glucose breath testing (GBT) for small intestinal bacterial overgrowth (SIBO) incorporated changes in glucose dosing and diagnostic cutoffs. We compared GBT positivity based on hydrogen and methane excretion and quantified symptoms during performance of the North American vs older modified Rome Consensus protocols. METHODS: GBT was performed using the North American protocol (75 g glucose, cutoffs >20 parts per million [ppm] hydrogen increase after glucose and >10 ppm methane anytime) in 3,102 patients vs modified Rome protocol (50 g glucose, >12 ppm hydrogen and methane increases after glucose) in 3,193 patients with suspected SIBO...
January 28, 2021: American Journal of Gastroenterology
Azza Shoaibi, Stephen Patrick Fortin, Rachel Weinstein, Jesse A Berlin, Patrick Ryan
INTRODUCTION: Famotidine has been posited as a potential treatment for coronavirus disease 2019 (COVID-19). We compared the incidence of COVID-19 outcomes (i.e., death and death or intensive services use) among hospitalized famotidine users vs proton pump inhibitors (PPIs) users, hydroxychloroquine users, or famotidine nonusers separately. METHODS: We constructed a retrospective cohort study using data from COVID-19 Premier Hospital electronic health records. The study population was COVID-19 hospitalized patients aged 18 years or older...
January 28, 2021: American Journal of Gastroenterology
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