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Journals Transactions of the Royal Soci...

Transactions of the Royal Society of Tropical Medicine and Hygiene

https://read.qxmd.com/read/38530874/towards-enhanced-control-of-mycetoma-a-roadmap-to-achieve-the-un-s-sustainable-development-goals-by-2030
#1
JOURNAL ARTICLE
Ahmed Fahal, Dallas J Smith, Borna Nyaoke, Kingsley Asiedu, Fabiana Falves, Supriya Warusavithanas, Daniel Argaw, Roderick Hay
Mycetoma is a neglected tropical disease (NTD) with devastating morbidity and stigma. Despite increased awareness and international collaboration, the burden of mycetoma is largely unknown and diagnosis and treatment are difficult. Addressing mycetoma globally aligns with several United Nation's Sustainable Development Goals (SDGs). Little progress has been made since the WHO's NTD roadmap publication in 2020. The Global Mycetoma Working Group proposes an enhanced mycetoma-control roadmap to meet the SDGs, stimulate progress and improve the lives of patients experiencing mycetoma...
March 26, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38517304/spatial-temporal-distribution-of-visceral-leishmaniasis-in-rio-de-janeiro-brazil-2001-2020-expansion-and-challenges
#2
JOURNAL ARTICLE
Alex de O Vasconcelos, Sandro J Bedoya-Pacheco, Rafael R Cunha E Silva, Mônica de A F M Magalhães, Tayana P S O de Sá, Cristina M G Dias, Patrícia S Meneguete, Paula M P de Almeida, Maria Inês F Pimentel
BACKGROUND: Visceral leishmaniasis results from complex interactions among humans, dogs and environment. Brazil accounts for 97% of cases in the Americas. METHODS: Twenty years (2001-2020) of the endemic disease in the state of Rio de Janeiro were studied. Incidence, lethality, sociodemographic and clinical characteristics were investigated, complemented with spatial methodologies (kernel and clusters). RESULTS: Ninety-seven human cases and 625 dogs were reported...
March 22, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38506281/antimicrobial-resistance-genetic-determinants-and-susceptibility-profile-of-pseudomonas-aeruginosa-isolated-from-clinical-samples-in-a-tertiary-hospital-in-ogun-state-nigeria
#3
JOURNAL ARTICLE
Oluwatoyin Olawunmi Adeyelu, Edidiong Nkiruka Essien, Valentine Adebote, Abraham Ajayi, Utibeima Udo Essiet, Adeyemi Isaac Adeleye, Stella Ifeanyi Smith
BACKGROUND: Genetic determinants are known to promote antibiotic resistance through horizontal gene transfer. METHODS: We molecularly characterized integrons, plasmid replicon types and metallo-β-lactamase-encoding genes of 38 Pseudomonas aeruginosa strains isolated from clinical samples. RESULTS: The P. aeruginosa isolates displayed high resistance (97.4%) to β-lactams. Seventeen (44.74%) of them possessed plasmids. Of the 17 isolates that possessed plasmids, 11 (64...
March 20, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38506276/comparison-of-mirna-profiles-in-the-immune-response-of-pediatric-acute-appendicitis-and-pediatric-enterobiasis-patients-caused-by-enterobius-vermicularis
#4
JOURNAL ARTICLE
Ayşe Betül Öztürk, Fadime Eroglu
BACKGROUND: The aim of this study was to determine and compare the miRNA profile in the immune response with the parasite in pediatric patients with acute appendicitis caused by Enterobius vermicularis and in pediatric patients with enterobiasis. METHODS: A total of 30 tissue samples, which were operated with the diagnosis of pediatric acute appendicitis in the last 10 y and Enterobius vermicularis was detected by histopathological findings, were analyzed. In addition, blood samples were taken from 30 pediatric patients diagnosed with enterobiasis for this study...
March 20, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38506271/motivation-opportunity-ability-behaviour-of-community-members-and-program-implementers-towards-mass-drug-administration-for-lymphatic-filariasis-elimination-in-india-a-systematic-review-and-implementation-priority
#5
JOURNAL ARTICLE
Abhinav Sinha, Sumegha Mohapatra, Krushna Chandra Sahoo, Shubhashisha Mohanty, Banamber Sahoo, Sanghamitra Pati, Prakash Kumar Sahoo
Lymphatic filariasis (LF) is a significant public health issue in India. Despite 10-15 rounds of mass drug administration (MDA) in India, the global LF elimination target of 2030 appears challenging. To strengthen the program, community and provider perspectives on ways to bridge a gap in MDA are needed. Through the motivation-opportunity-ability-behaviour (MOAB) lens, we systematically reviewed the facilitators and barriers encountered in LF elimination in India. We followed Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines...
March 20, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38465481/-we-no-longer-experience-the-same-pain-a-cross-sectional-study-assessing-the-impact-of-heart-and-sole-africa-s-podoconiosis-prevention-education-program
#6
JOURNAL ARTICLE
Agazi Fitsum Gebreselassie, Natnael Shimelash, Ahamed Kallon, George Mkondo, Tonya Huston, Janna M Schurer
BACKGROUND: Podoconiosis is a non-infectious neglected tropical disease caused by long-term exposure to irritant volcanic soils. It results in severe physical, psychological and financial consequences. Heart and Sole Africa (HASA) is a non-governmental, community-based organization providing management to podoconiosis patients in Rwanda. We sought to analyze the impact of their program on the lives of patients. METHODS: Quantitative surveys recorded the participants' demographics, adherence to HASA's management recommendations and changes in quality of life (QOL)...
March 11, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38456460/-my-feet-cannot-stand-on-their-own-podoconiosis-patient-healthcare-expenditures-and-income-impacts-in-rwanda
#7
JOURNAL ARTICLE
Janna M Schurer, Ursin Bayisenge, Dieudonne Hakizimana, Ellen Rafferty
BACKGROUND: Podoconiosis is a progressive and debilitating form of tropical lymphoedema endemic to Rwanda. Although the physical and psychological consequences are well known, few studies have evaluated the financial burden of podoconiosis. METHODS: This cross-sectional, quantitative study aimed to characterize direct treatment costs and impacts on annual earnings among individuals living with podoconiosis. Participants from two highly endemic districts were invited to complete a survey focused on health-seeking history, insurance status, out-of-pocket costs and income changes...
March 8, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38411919/exploring-the-latency-period-in-chagas-disease-duration-and-determinants-in-a-cohort-from-colombia
#8
JOURNAL ARTICLE
Mario Javier Olivera, Lyda Muñoz
BACKGROUND: Chagas disease has a varying latency period, the time between infection and onset of cardiac symptoms, due to multiple factors. This study seeks to identify and understand these factors to enhance our knowledge of the disease. METHODS: A retrospective follow-up study was conducted in Colombia on patients with indeterminate chronic Chagas disease. Medical files were examined to evaluate the disease latency time using time ratios (TRs) and the AFT Weibull model...
February 27, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38401052/accuracy-of-commercial-elisa-and-ict-for-screening-schistosomiasis-infections-at-a-low-endemicity-area-in-brazil
#9
JOURNAL ARTICLE
Lida M S Ramos, Danielle S C A Pereira, Laila O V Oliveira, Carlos Graeff-Teixeira
BACKGROUND: Control interventions recommended by the World Health Organization have successfully resulted in low-intensity schistosomiasis transmission areas. To achieve elimination of transmission, new diagnostic screening tools are needed to overcome less than adequate sensitivity of the currently used Kato-Katz faecal thick smear method. Ideally, in-house serological tests should be avoided due to not having a continuous supply of kits as would be necessary for large population studies...
February 24, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38339958/lessons-from-the-field-compound-specific-management-in-acute-pesticide-poisoning
#10
JOURNAL ARTICLE
Vasundhara R Verma, Thomas Lamb, Md Abdus Sattar, Aniruddha Ghose, Michael Eddleston
Pesticide poisoning is a common medical emergency in the rural tropics, with significant associated mortality. Pesticide poisoning is an umbrella term that encompasses a wide variety of substances with differing clinical toxidromes and outcomes. Despite this, confirmation of the specific compound ingested is rarely performed. In this Lessons from the Field, we argue that pesticide-specific management is integral to optimise management. Using data from a quality improvement project in Chittagong, Bangladesh, we demonstrate that identifying the specific compound is possible in most patients through careful history taking and examination of the pesticide bottle...
February 10, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38324406/prevalence-of-delayed-initiation-of-rabies-postexposure-prophylaxis-and-factors-influencing-it-among-animal-bite-victims-from-eastern-uttar-pradesh-india
#11
JOURNAL ARTICLE
Imran Ahmed Khan, Md Abu Bashar, Sufiya Mohsin, D K Shrivastava
BACKGROUND: In a rabies-endemic country like India, every animal bite is potentially taken as rabid exposure and timely and appropriate postexposure prophylaxis (PEP) is crucial as rabies is an almost 100% fatal disease. METHODS: A retrospective record-based study was conducted at an anti-rabies clinic (ARC) in Eastern Uttar Pradesh, India. Data of the animal bite victims attending the ARC for PEP from January to December 2022 were extracted from the records. A semistructured questionnaire was used for collecting information regarding the interval between exposure and the initiation of anti-rabies PEP, age, gender, residence, the bite site on the body, category of exposure and other risk factors associated with the delay in PEP...
February 7, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38291854/covid-19-vaccination-during-pregnancy-and-adverse-perinatal-outcomes-a-systematic-review-and-meta-analysis
#12
JOURNAL ARTICLE
Jia Wang, Yuzhi Deng, Weijing Wang
We aimed to estimate the associations between coronavirus disease 2019 (COVID-19) vaccination during pregnancy and the risks of adverse perinatal outcomes. We performed a literature search in PubMed, Web of Science and Embase to identify eligible studies published up to 24 September 2023, yielding 39 included studies. Pooled relative risks (RRs) with 95% confidence intervals (CIs) were calculated with a random effects model. The pooled results showed that COVID-19 vaccination during pregnancy (any type or dose of COVID-19 vaccination during any trimester) was not associated with an increased risk of adverse perinatal outcomes...
January 31, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38288655/insights-into-parasites-and-covid-19-co-infections-in-iran-a-systematic-review
#13
JOURNAL ARTICLE
Soheila Molaei, Shabnam Asfaram, Zahra Mashhadi, Behnam Mohammadi-Ghalehbin, Sohrab Iranpour
BACKGROUND: It is well-documented that using immunosuppressive drugs such as corticosteroids or cytokine blockers in treating coronavirus disease 2019 (COVID-19) increases the risk of co-infections. Here we systematically summarized the cases of COVID-19-associated parasitic infections (CAPIs) in Iran. METHODS: From 19 February 2020 to 10 May 2023, all studies on Iranian patients suffering from CAPIs were collected from several databases using a systematic search strategy...
January 30, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38279781/clinical-characteristics-diagnosis-treatment-and-outcomes-of-patients-living-with-hiv-and-co-infected-with-tuberculosis-and-histoplasmosis-a-5-y-retrospective-case-series
#14
JOURNAL ARTICLE
María Eugenia Castellanos Reynosa, Maria Eugenia Caal, Danicela Mercado, Narda Medina, Juan Carlos Pérez, Theophilus I Emeto, Eduardo Arathoon
BACKGROUND: In Latin America, tuberculosis (TB) and histoplasmosis are two of the most frequent opportunistic infections affecting people living with human immunodeficiency virus (HIV). However, there are limited data on the clinical characteristics and outcomes of patients with concurrent TB and histoplasmosis infections. METHODS: This was a retrospective observational study to describe the clinical, epidemiological and laboratory characteristics and outcomes of 21 patients living with HIV (PLHIV) who were diagnosed with concurrent histoplasmosis and TB between 2017 and 2021 in Guatemala City, Guatemala...
January 27, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38269435/the-centenary-of-the-leprosy-relief-association-lepra-a-moment-for-celebration-and-reflection%C3%A2
#15
JOURNAL ARTICLE
Irene Allen, Diana N Lockwood, Roderick J Hay
The year 2024 is the Centenary of the foundation of the Leprosy Relief Association (Lepra), formerly the British Empire Leprosy Relief Association (BELRA). The name of the organization changed to the LEProsy Relief Association (LEPRA) in 1976 but has been known as Lepra since 2008. Over the years it has worked closely with members and office holders of the Royal Society of Tropical Medicine and Hygiene. Its work has encompassed activities from the earliest initiatives to ensure appropriate living conditions for those with the disease to the development of leprosy chemotherapy...
January 25, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38261661/the-seroprevalence-of-toxocariasis-and-related-risk-factors-in-children-in-ho-chi-minh-city-vietnam-results-from-a-school-based-cross-sectional-study
#16
JOURNAL ARTICLE
Thieu V Ha, Tien T N Vo, Duy K H Dang, Y M L Tran, Thanh V Kim, Duc H Le, Lan-Anh T Do, Hong K Tang
BACKGROUND: Children are especially vulnerable to Toxocara infection and its severe complications; however, there have not been any published data on the disease prevalence and treatment effectiveness in the population of Vietnamese children. This study was conducted to determine the prevalence of toxocariasis and explore factors associated with Toxocara infection in children aged 3-15 y in Ho Chi Minh City, Vietnam. METHODS: We conducted a cross-sectional study using a multistage cluster sampling approach in public schools...
January 23, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38243827/temporal-trends-and-spatial-and-spatiotemporal-distribution-of-schistosomiasis-mansoni-in-northeast-brazil-between-2005-and-2016
#17
JOURNAL ARTICLE
Vitória Jordana Bezerra Alencar, Pedro Dantas Lima, João Paulo Vieira Machado, Maria Wilma da Silva Lima, Sheilla da Conceição Gomes, Wandklebson Silva da Paz, Rosália Elen Santos Ramos, Letícia Pereira Bezerra, Israel Gomes de Amorim Santos
BACKGROUND: Schistosoma mansoni is a parasitic disease of great magnitude for Brazilian public health. We aimed to analyse the temporal trend and spatial and spatiotemporal distribution of positivity rates for schistosomiasis mansoni in northeast Brazil. METHODS: This is a descriptive study with an ecological approach, carried out between 2005 and 2016. We calculated the positivity rate for the disease and then performed a segmented trend analysis (Joinpoint). For spatial analysis, we smoothed the positivity rates using the local empirical Bayesian method...
January 19, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38240067/task-sharing-for-the-management-of-leprosy-by-nurses-in-a-tertiary-healthcare-setting-of-northern-india
#18
JOURNAL ARTICLE
Pratibha, Kavita, Hitaishi Mehta, Tarun Narang, Shubhmohan Singh
BACKGROUND: This study aimed to assess the effectiveness of nurse-led interventions in managing leprosy due to a shortage of dermatologists and other healthcare professionals. METHODS: A total of 100 leprosy patients were divided into experimental (n=50) and control groups (n=50). The intervention included face-to-face counseling by a trained nurse, motivational videos and exercise demonstrations. The control group received standard care. The primary outcome of interest was treatment adherence (Adherence to Refills and Medications Scale); other assessed outcomes included changes in perceived stigma (Stigma Assessment and Reduction of Impact scale), depression (Patient Health Questionnaire-9), anxiety (Generalized Anxiety Disorder seven-item) and quality of life (WHO QOL-BREF Scale) from baseline to week 8...
January 18, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38240056/phylogenetic-analysis-of-acanthamoeba-isolated-from-soil-samples-and-nasal-cavities-of-patients-with-malignancy-a-public-health-concern-in-the-northwest-of-iran
#19
JOURNAL ARTICLE
Ali Pezeshki, Shadi Tajic, Parvin Farahmandian, Ali Haniloo, Abbas Mahmmodzadeh, Maryam Niyyati, Hamed Behniafar
BACKGROUND: The genus Acanthamoeba is reported from various environmental sources and can cause multiple complications, including chronic amoebic aeratitis and amoebic granulomatous encephalitis. This study investigated the presence and genotyping of Acanthamoeba in the soil of parks and patients with malignancies referred to health centers in Zanjan city, Iran. METHODS: In this cross-sectional study, 200 soil samples were collected from amusement parks in Zanjan city from September 2017 to May 2018...
January 18, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38226501/seroprevalence-of-dengue-and-chikungunya-viruses-among-urban-refugees-in-klang-valley-malaysia
#20
JOURNAL ARTICLE
Norhidayu Sahimin, Zhao Xuan Low, Pouya Hassandarvish, Izzah Ruzana Mohd Hanapi, Siti Nursheena Mohd Zain, Hasmawati Yahaya, Sazaly Abu Bakar
BACKGROUND: Mosquito-borne diseases pose a significant global public health threat, with Malaysia's Klang Valley experiencing numerous outbreaks in densely populated urban areas. METHODS: This study aimed to estimate the seroprevalence of anti-dengue and anti-chikungunya antibodies among urban refugees in the Klang Valley, Malaysia, and identify associated risk factors. RESULTS: High seroprevalence of anti-dengue immunoglobulin G (IgG) and IgM (60...
January 16, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
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