journal
https://read.qxmd.com/read/38635060/effects-of-dependent-care-theory-based-post-surgical-home-care-intervention-on-self-care-symptoms-and-caregiver-burden-in-patients-with-primary-brain-tumor-and-their-caregivers-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Derya Dağdelen, Handan Zincir
PURPOSE: This study aimed to examine the effect of dependent care theory-based post-surgical home care intervention on self-care, symptoms, and caregiver burden in primary brain tumor patients and their caregivers. METHODS: A parallel-group randomized controlled trial was conducted with patients who underwent surgery for a primary brain tumor between March 2019 and January 2020 in a tertiary hospital and with caregivers who cared for them at home. Eligible patients and caregivers were determined by block randomization...
April 18, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38635051/effect-of-radiotherapy-on-the-surface-roughness-and-microhardness-of-contemporary-bioactive-restorative-materials
#2
JOURNAL ARTICLE
Cansu Atalay, A Ruya Yazici
OBJECTIVE: The aim of this in vitro study was to evaluate the effect of radiotherapy on the surface microhardness and roughness of different bioactive restorative materials. MATERIALS AND METHODS: A total of 60-disc specimens (5 mm × 2 mm) were performed in four groups (n = 15 each) from Equia Forte HT, Cention N, Activa Bioactive Restorative, and Beautifil II. Following the polishing procedure (600, 1000, 1200 grit silicon carbide papers), all specimens were irradiated at 2 Gy per fraction, five times a week for a total dose of 70 Gy in 30 fractions over 7 weeks...
April 18, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38635029/anxiety-depression-urinary-continence-and-sexuality-in-patients-undergoing-radical-prostatectomy-preliminary-findings
#3
JOURNAL ARTICLE
Marco Tozzi, Letizia Maria Ippolita Jannello, Marco Silvaggi, Paolo Maria Michetti
OBJECTIVES: Evaluate the relationship between psychological distress, namely anxiety and depression, with urinary continence and recovery of erectile function in patients undergoing radical prostatectomy (RP). METHODS: We retrospectively analyzed data from 33 consecutive patients who underwent RP in a single tertiary-referral academy between 01/2018 to 01/2019. We used the International Index of Erectile Function (IIEF-15), the Sexual Complaints Screener for Men (SCS-M), and the Hospital Anxiety and Depression Scale (HADS), validated questionnaires for the assessment of sexual function, anxiety, and depression experiences, respectively...
April 18, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38632192/the-potential-impact-of-exercise-upon-symptom-burden-in-adolescents-and-young-adults-undergoing-cancer-treatment
#4
JOURNAL ARTICLE
Claire Munsie, Jay Ebert, David Joske, Jo Collins, Timothy Ackland
PURPOSE: Adolescents and young adults (AYAs) experience vast symptom burden resulting from cancer treatment-related toxicities (TRTs). Evidence supports integrated exercise to mitigate several TRTs in other cohorts; however, evidence in AYAs is lacking. Conventional reporting of TRTs adopts a maximum grade approach failing to recognise the trajectory over time, of persistent, or lower grade toxicities. Alternatively, longitudinal analysis of toxicities over time (ToxT) may provide clinically meaningful summaries of this data...
April 17, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38632132/rates-of-paclitaxel-hypersensitivity-reactions-using-a%C3%A2-modified-markman-s-infusion-protocol-as-primary-prophylaxis
#5
JOURNAL ARTICLE
Rebecca Symons, Fiona Heath, Jennifer Duggan, Kim Tam Bui, Lily Byun, Michael Friedlander, Yeh Chen Lee
PURPOSE: Markman's desensitisation protocol allows successful retreatment of patients who have had significant paclitaxel hypersensitivity reactions. We aimed to reduce the risk and severity of paclitaxel hypersensitivity reactions by introducing this protocol as primary prophylaxis. METHODS: We evaluated all patients with a gynaecological malignancy receiving paclitaxel before (December 2018 to September 2019) and after (October 2019 to July 2020) the implementation of a modified Markman's desensitisation protocol...
April 17, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38630197/the-emerging-emetogenicity-of-trifluridine-tipiracil-tas%C3%A2-102-from-patient-self-reporting-a-multicenter-prospective-observational-study
#6
MULTICENTER STUDY
Hironori Fujii, Masami Tsuchiya, Daichi Watanabe, Ryo Otsuka, Daisuke Hirate, Katsuyuki Takahashi, Makiko Go, Toshihiro Kudo, Kazuhiro Shimomura, Yosuke Ando, Shinya Tani, Takao Takahashi, Katsuhisa Hayashi, Miki Chin, Naomi Matsunami, Masaya Takahashi, Akiko Hasegawa, Takashi Uchida, Hironobu Hashimoto, Akiko Kubo, Nobuhisa Matsuhashi, Akio Suzuki, Junichi Nishimura, Naoki Inui, Hirotoshi Iihara
BACKGROUND: Trifluridine/tipiracil (TAS-102) is an oral anticancer drug with adequate efficacy in unresectable colorectal cancer, but frequently also induces chemotherapy-induced nausea and vomiting (CINV). To investigate the occurrence of CINV and antiemetic therapy in patients with colorectal cancer treated with TAS-102 (JASCC-CINV 2001). METHODS: We conducted a multicenter, prospective, observational study in patients with colorectal cancer who received TAS-102 without dose reduction for the first time...
April 17, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38627334/evaluation-of-chemotherapy-induced-nausea-and-vomiting-in-pediatric-patients-with-high-grade-glioma-treated-with-lomustine-a-case-series
#7
JOURNAL ARTICLE
Kim P J Schellekens, Sarah Babette Hageman, Els C Haverkate, Marianne D van de Wetering, Frederike K Engels, Aeltsje Brinksma, Evelien de Vos-Kerkhof
PURPOSE: Although lomustine has been used as a chemotherapeutic agent for decades, no recommendation on appropriate chemotherapy-induced nausea and vomiting (CINV) prophylaxis is available. As CINV is considered one of the most bothersome side effects of chemotherapy, adequate prophylaxis is of relevance to improve quality of life during cancer treatment. The aim of this retrospective case series was to report the incidence and severity of CINV in pediatric patients with high-grade glioma treated with lomustine and to formulate recommendations for appropriate CINV prophylaxis...
April 16, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38625539/a-single-arm-pilot-of-myinspiration-a-novel-digital-resource-to-support-spiritual-needs-of-patients-undergoing-cancer-directed-surgery
#8
JOURNAL ARTICLE
Elizabeth Palmer Kelly, Maryanna Klatt, Jacqueline Caputo, Timothy M Pawlik
PURPOSE: This study aimed to assess the feasibility, acceptability, and satisfaction associated with the MyInspiration intervention, a digital spiritual support tool for patients undergoing cancer surgery. Additionally, we evaluated changes in spiritual well-being and the ability to find meaning in their experience with cancer before and after the intervention. METHODS: This was a prospective, single-arm pilot study. Feasibility and acceptability were assessed by ratio of participants who completed all assessments among individuals who had signed consent forms...
April 16, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38622350/-like-not-having-an-arm-a-qualitative-study-of-the-impact-of-visitor-restrictions-on-cancer-care-during-the-covid-19-pandemic
#9
JOURNAL ARTICLE
Laura M Holdsworth, Rachel Siden, Bonnie O Wong, Mae Verano, Anna Sophia Lessios, Holly K Tabor, Lidia Schapira, Rebecca Aslakson
PURPOSE: Visitor restriction policies to prevent the spread of COVID-19 among patients and clinicians were widespread during the pandemic, resulting in the exclusion of caregivers at key points of cancer care and treatment decision-making. The aim of this study was to explore how visitor restrictions impacted cancer treatment decision-making and care from patient and physician perspectives. METHODS: Sixty-seven interviews, including 48 cancer patients and 19 cancer and palliative care physicians from four academic cancer centers in the USA between August 2020 and July 2021...
April 16, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38619660/the-impact-of-social-support-on-benefit-finding-among-patients-with-advanced-lung-cancer-and-their-caregivers-based-on-actor-partner-interdependence-mediation-model
#10
JOURNAL ARTICLE
Mengjiao Zhao, Na Na, Naijiao Xing, Hua Zhu, Guixia Wu, Guangyi Xu, Yunxia Jiang
PURPOSE: Advanced lung cancer and its treatment serve as a sudden stressful event that profoundly impacts the psychological experience of both the patients and their primary caregiver. This study used dyadic analyses to explore the dyadic effects of social support on benefit finding and whether hope level mediates the patient-caregiver dyads in advanced lung cancer. METHODS: Two hundred ninety-five pairs of patients with advanced lung cancer and primary caregivers completed the Social Support Rating Scale (SSRS), the Herth Hope Index (HHI), and the Benefit Finding Scale (BFS)...
April 15, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38613655/a-qualitative-study-on-experiences-of-stigma-among-postoperative-oral-cancer-patients
#11
JOURNAL ARTICLE
Jie Zhu, Chu-Xia Tan, Jia-Yi Guo, Rong-Hong Yang, Man Ye
AIM: This study aimed to explore the characteristics of stigma in postoperative oral cancer patients to provide a reference for the formulation of targeted intervention measures. METHODS: A qualitative study was conducted on 25 postoperative oral cancer patients in a tertiary A hospital in Hunan, China, from March to July 2021. Semi-structured face-to-face interviews focused on experiences of stigma were performed. The interview data was analyzed using the NVivo V...
April 13, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38607568/the-use-of-interventional-procedures-for-cancer-pain-a-brief-review
#12
REVIEW
Yi-Ching Lee, Timothy Brake, Emma Zhao, Alix Dumitrescu, Wei Lee, Benjamin Tassie, Kok-Eng Khor, Andy Yi-Yang Wang
CONTEXT: Pain is a common experience in people living with cancer. Concerns around opioid prescribing have seen a move toward a multi-modality management approach, which includes interventional pain procedures. PURPOSE: In this paper we discuss the interventional pain procedures used to treat cancer pain at two major tertiary centers in Australia. METHODS AND RESULTS: This expert review provides practical insights on cancer pain management from healthcare providers in different specialties...
April 12, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38607445/perceived-control-self-management-efficacy-and-quality-of-life-in-patients-treated-with-radiation-therapy-for-breast-cancer-a-longitudinal-study
#13
JOURNAL ARTICLE
Hai-Mei Qu, Hong-Yue Zhong, Tian Xiao, Yan-Jun Li, Pan Ren, Xiao-Ju Chen
OBJECTIVE: This longitudinal study aims to examine the present state of perceived control, self-management efficacy, and overall quality of life (QoL) in patients with breast cancer undergoing radiotherapy, and gain insight into the dynamic trends and factors that influence the quality of life experienced by patients during the course of radiotherapy. METHODS: Participants completed the Cancer Experience and Efficacy Scale (CEES), Strategies Used by People to Promote Health (SUPPH), and Functional Assessment of Cancer Therapy- Breast (FACT-B)...
April 12, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38602620/physical-health-related-quality-of-life-trajectories-over-two-years-following-breast-cancer-diagnosis-in-older-women-a-secondary-analysis
#14
JOURNAL ARTICLE
Shan S Wong, Beverly J Levine, Kimberly J Van Zee, Elizabeth Z Naftalis, Nancy E Avis
PURPOSE: To identify distinct trajectories of physical health-related quality of life (HRQoL) in older women over the first two years following breast cancer diagnosis, and to examine characteristics associated with trajectory group membership. METHODS: A secondary analysis of a longitudinal study of women diagnosed with stage I-III breast cancer who completed surveys within eight months of diagnosis and six, twelve, and eighteen months later that focuses on a subset of women aged ≥ 65 years (N = 145)...
April 11, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38600364/increasing-physical-activity-among-older-adults-with-gynecologic-cancers-a-qualitative-study
#15
JOURNAL ARTICLE
Brenda Vega, Ria Desai, Payton Solk, June M McKoy, Ann Marie Flores, Siobhan M Phillips, Emma L Barber
PURPOSE: The purpose of this study was to gain an understanding of older gynecologic cancer patients' preferences and opinions related to physical activity during chemotherapy, including interventions to promote physical activity. METHODS: Gynecologic cancer patients 60 years or older receiving chemotherapy at a single institution within the last 12 months completed questionnaires and a semi-structured interview asking about their preferences for physical activity interventions aimed at promoting physical activity while receiving treatment...
April 11, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38598052/frequency-and-characteristics-of-immune-related-thyroid-adverse-events-in-patients-with-resected-stage-iii-iv-melanoma-treated-with-adjuvant-pd-1-inhibitors-a-national-cohort-study
#16
MULTICENTER STUDY
Stine K Christensen, Mette L Winther, Ida J Laursen, Freja S Madsen, Carsten Brink, Thomas H Brix, Eva Ellebaek, Inge Marie Svane, Frederikke S Hansen, Charlotte Haslund, Olivia K Laursen, Henrik Schmidt, Ida D Larsen, Lars Bastholt, Christina H Ruhlmann
PURPOSE: Immune-related thyroid adverse events (irTAEs) occur frequently following immune checkpoint inhibitor (ICI) therapy. The purpose of this study is to provide knowledge about the incidence, clinical timeline characteristics, associated factors of irTAEs, and potential impact on treatment efficacy in patients with melanoma receiving adjuvant ICI therapy. METHODS: A national multicenter retrospective cohort study of patients with resected stage III/IV melanoma treated with adjuvant PD-1 inhibitors between November 2018 and December 2020...
April 10, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38594390/financial-difficulties-experienced-by-patients-with-gastrointestinal-stromal-tumours-gist-in-the-netherlands-data-from-a-cross-sectional-multicentre-study
#17
MULTICENTER STUDY
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, Hans Gelderblom, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
PURPOSE: This study aims to (1) explore the prevalence of patient-reported financial difficulties among GIST patients, differentiating between those currently undergoing tyrosine kinase inhibitor (TKI) treatment and those who are not; (2) investigate associations between financial difficulties and sociodemographic and clinical characteristics, work, cancer-related concerns, anxiety and depression and (3) study the impact of financial difficulties on health-related quality of life. METHODS: A cross-sectional study was conducted among Dutch GIST patients diagnosed between 2008 and 2018, who were invited to complete a one-time survey between September 2020 and June 2021...
April 10, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38594320/2020-asco-2023-nccn-2023-mascc-esmo-and-2019-cco-a-comparison-of-antiemetic-guidelines-for-the-treatment-of-chemotherapy-induced-nausea-and-vomiting-in-cancer-patients
#18
REVIEW
Samantha K F Kennedy, Shannon Goodall, Shing Fung Lee, Carlo DeAngelis, Allison Jocko, Flay Charbonneau, Katie Wang, Mark Pasetka, Yoo-Joung Ko, Henry C Y Wong, Adrian Wai Chan, Thenugaa Rajeswaran, Milena Gojsevic, Edward Chow, Richard J Gralla, Terry L Ng, Katarzyna J Jerzak
Chemotherapy-induced nausea and vomiting (CINV) is a common toxicity that may impair the quality of life of patients with various malignancies ranging from early to end stages. In light of frequent changes to the guidelines for optimal management of CINV, we undertook this narrative review to compare the most recent guidelines published by ASCO (2020), NCCN (2023), MASCC/ESMO (2023), and CCO (2019). The processes undertaken by each organization to evaluate existing literature were also described. Although ASCO, NCCN, MASCC/ESMO, and CCO guidelines for the treatment and prevention of CINV share many fundamental similarities, the literature surrounding low and minimal emetic risk regimens is lacking...
April 10, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38592525/characterising-vincristine-induced-peripheral-neuropathy-in-adults-symptom-development-and-long-term-persistent-outcomes
#19
JOURNAL ARTICLE
Tiffany Li, Terry Trinh, Annmarie Bosco, Matthew C Kiernan, David Goldstein, Susanna B Park
BACKGROUND: Decades following the introduction of vincristine as treatment for haematological malignancies, vincristine-induced peripheral neuropathy (VIPN) remains a pervasive, untreatable side-effect. However there remains a gap in understanding the characteristics of VIPN in adults. This study presents a comprehensive phenotyping of VIPN. METHODS: Adult patients (n = 57; age = 59.8 ± 14.6) were assessed cross-sectionally following completion of vincristine (months post treatment = 16...
April 9, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38589646/efficacy-of-delayed-pegfilgrastim-administration-following-consolidation-therapy-with-high-dose-cytarabine-hidac-in-acute-myeloid-leukemia-aml-patients
#20
JOURNAL ARTICLE
Spencer K Yingling, Joshua Francis, Kelsea Seago, Salah Ud Din Safi, Sijin Wen, Aaron Cumpston
PURPOSE: To study the effects of delaying pegfilgrastim administration following high-dose cytarabine (HiDAC) consolidation in AML patients on time to neutrophil count recovery, infectious complications, and survival. METHODS: Single-center retrospective chart review of 55 patients receiving pegfilgrastim as early administration (within 72 h) or delayed administration (after 72 h) of HiDAC. RESULTS: The difference in neutrophil recovery time was similar between the early and delayed groups (18 days versus 19 days, p < 0...
April 9, 2024: Supportive Care in Cancer
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