journal
https://read.qxmd.com/read/37737686/intravenous-ketorolac-substantially-reduces-opioid-use-and-length-of-stay-after-lumbar-fusion-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Sravisht Iyer, Michael E Steinhaus, Gregory S Kazarian, Evangelia M Zgonis, Matthew E Cunningham, James C Farmer, Han Jo Kim, Darren R Lebl, Russel C Huang, Virginie Lafage, Frank J Schwab, Sheeraz Qureshi, Federico P Girardi, Bernard A Rawlins, James D Beckman, Jeffrey J Varghese, Hamna Muzammil, Renaud Lafage, Harvinder S Sandhu
STUDY DESIGN: Randomized, double-blinded, placebo-controlled trial. OBJECTIVE: Examine the effect of intravenous ketorolac (IV-K) on hospital opioid use compared to IV placebo (IV-P) and IV acetaminophen (IV-A). SUMMARY OF BACKGROUND DATA: Controlling postoperative pain while minimizing opioid use following lumbar spinal fusion is an important area of study. METHODS: Patients aged 18-75 years undergoing 1-2 level lumbar fusion between April 2016 - December 2019 were included...
September 22, 2023: Spine
https://read.qxmd.com/read/37737684/radiographic-and-patient-reported-outcomes-anteriorly-placed-transforaminal-lumbar-interbody-fusion-cage-vs-anterior-lumbar-interbody-fusion-with-posterior-instrumentation
#2
JOURNAL ARTICLE
Yunsoo Lee, Jeremy C Heard, Michael A McCurdy, Mark J Lambrechts, Sebastian I Fras, William Purtill, Ben Millar, Samantha Kolowrat, Tariq Z Issa, Nicholas D D'Antonio, Jeffrey A Rihn, Mark F Kurd, I David Kaye, Jose A Canseco, Alexander R Vaccaro, Alan S Hilibrand, Christopher K Kepler, Gregory D Schroeder
STUDY DESIGN: Retrospective Cohort Study. OBJECTIVE: To compare outcomes in anteriorly placed transforaminal lumbar interbody fusions (TLIFs) and anterior lumbar interbody fusions (ALIFs). SUMMARY OF BACKGROUND DATA: TLIF and ALIF are surgical techniques that have become more prevalent in recent years. Although studies have compared the two, none have considered TLIFs with anteriorly placed cages, which may serve as a better comparison to ALIFs...
September 22, 2023: Spine
https://read.qxmd.com/read/37737672/concerning-the-article-feasibility-of-c2-pedicle-screw-fixation-with-the-in-out-in-technique-for-patients-with-basilar-invagination
#3
JOURNAL ARTICLE
Lu-Ping Zhou, Ren-Jie Zhang, Cai-Liang Shen
No abstract text is available yet for this article.
September 22, 2023: Spine
https://read.qxmd.com/read/37737670/letter-to-the-editor-re-postoperative-dural-sac-cross-sectional-area-as-an-association-for-outcome-after-surgery-for-lumbar-spinal-stenosis-clinical-and-radiological-results-from-the-nordsten-spinal-stenosis-trial-spine-may-15-2023
#4
JOURNAL ARTICLE
https://read.qxmd.com/read/37728119/recovery-kinetics-following-cervical-spine-surgery
#5
JOURNAL ARTICLE
Tejas Subramanian, Daniel Shinn, Maximilian Korsun, Pratyush Shahi, Tomoyuki Asada, Troy B Amen, Omri Maayan, Sumedha Singh, Kasra Araghi, Olivia C Tuma, Nishtha Singh, Chad Simon, Joshua Zhang, Evan D Sheha, James E Dowdell, Russel C Huang, Todd J Albert, Sheeraz A Qureshi, Sravisht Iyer
STUDY DESIGN: Retrospective review of a prospectively maintained multi-surgeon registry. OBJECTIVE: To study recovery kinetics and associated factors following cervical spine surgery. SUMMARY OF BACKGROUND DATA: Few studies have described return to activities cervical spine surgery. This is a big gap in the literature as preoperative counseling and expectations before surgery are important. MATERIALS AND METHODS: Patients that underwent either anterior cervical discectomy and fusion (ACDF) or cervical disc replacement (CDR) were included...
September 19, 2023: Spine
https://read.qxmd.com/read/37706515/bruton-s-tyrosine-kinase-in-ankylosing-spondylitis
#6
JOURNAL ARTICLE
Hsien-Tzung Liao, Chun-Hsiung Chen
STUDY DESIGN: Prospective case-control study. OBJECTIVE: To explore the role of Bruton's tyrosine kinase (BTK) in ankylosing spondylitis (AS). SUMMARY OF BACKGROUND DATA: AS substantially affects patients, impairing range of motion in the whole spine and peripheral joints, as well as overall quality of life. However, surveillance for this condition is limited and biomarkers that can predict disease activity are not well documented. METHODS: The expression of the BTK gene in peripheral blood mononuclear cells was measured using flow cytometry and real time quantitative polymerase chain reaction (qPCR) in 36 AS patients and 30 healthy controls...
September 14, 2023: Spine
https://read.qxmd.com/read/37702242/quantifying-typical-progression-of-adolescent-idiopathic-scoliosis-longitudinal-three-dimensional-mri-measures-of-disc-and-vertebral-deformities
#7
JOURNAL ARTICLE
Fraser R Labrom, Maree T Izatt, Geoffrey N Askin, Robert D Labrom, Andrew P Claus, J Paige Little
STUDY DESIGN: Prospective cohort study. OBJECTIVE: Detail typical three-dimensional segmental deformities and their rates of change that occur within developing adolescent idiopathic scoliosis (AIS) spines over multiple timepoints. SUMMARY OF BACKGROUND DATA: AIS is a potentially progressive deforming condition that occurs in three-dimensions of the scoliotic spine during periods of growth. However, there remains a gap for multiple time-point segmental deformity analysis in AIS cohorts during development...
September 13, 2023: Spine
https://read.qxmd.com/read/37732462/the-role-of-en-bloc-resection-in-the-modern-era-for-primary-spine-tumors
#8
JOURNAL ARTICLE
Caleb M Yeung, Mark Bilsky, Patrick J Boland, Max Vaynrub
STUDY DESIGN: Literature review. OBJECTIVE: The aim of this review is to provide an overview of benign and malignant primary spine tumors and a balanced analysis of the benefits and limitations of (and alternatives to) surgical treatment with en bloc resection. SUMMARY OF BACKGROUND DATA: Primary spine tumors are rare but have the potential to cause severe morbidity, either from the disease itself or as a result of treatment. The prognosis, goals, and treatment options vary significantly with the specific disease entity...
September 12, 2023: Spine
https://read.qxmd.com/read/37698284/functional-alignment-within-the-fusion-in-adult-spinal-deformity-asd-improves-outcomes-and-minimizes-mechanical-failures
#9
JOURNAL ARTICLE
Fares Ani, Ethan W Ayres, Alex Soroceanu, Gregory M Mundis, Justin S Smith, Jeffrey L Gum, Alan H Daniels, Eric O Klineberg, Christopher P Ames, Shay Bess, Christopher I Shaffrey, Frank J Schwab, Virginie Lafage, Themistocles S Protopsaltis
STUDY DESIGN: Retrospective review of an adult deformity database. OBJECTIVE: To identify Pelvic Incidence (PI) and age-appropriate physical function alignment targets using a component angle of T1- Pelvic Angle (TPA) within the fusion to define correction and their relationship to proximal junctional kyphosis (PJK) and clinical outcomes. SUMMARY OF BACKGROUND DATA: In preoperative planning, a patient's PI is often utilized to determine alignment target...
September 12, 2023: Spine
https://read.qxmd.com/read/37698271/understanding-the-interplay-between-paraspinal-muscle-atrophy-and-lumbar-endplate-degeneration-a-3-year-longitudinal-study
#10
JOURNAL ARTICLE
Lukas Schönnagel, Jiaqi Zhu, Ali E Guven, Gaston Camino-Willhuber, Soji Tani, Thomas Caffard, Henryk Haffer, Maximilian Muellner, Erika Chiapparelli, Krizia Amoroso, Artine Arzani, Manuel Moser, Jennifer Shue, Ek T Tan, John A Carrino, Thomas Jöns, Andrew A Sama, Federico P Girardi, Frank P Cammisa, Alexander P Hughes
STUDY DESIGN: Retrospective analysis of longitudinal data. OBJECTIVE: To assess the association between the paraspinal musculature (PM) and lumbar endplate degeneration. BACKGROUND: The PM is essential for spinal stability, while the vertebral endplate is pivotal for nutrient transport and force distribution. The clinical importance of both has been highlighted in recent literature, though little is known about their interaction. METHODS: We identified patients with lumbar MRI scans due to low back pain, with a 3-year interval between MRI scans...
September 12, 2023: Spine
https://read.qxmd.com/read/37694562/increasing-cervical-kyphosis-correlates-with-cervical-degenerative-disc-disease-in-patients-with-adolescent-idiopathic-scoliosis
#11
JOURNAL ARTICLE
Adrian Lin, David L Skaggs, Lindsay M Andras, Vernon Tolo, Benita Tamrazi, Kenneth D Illingworth
STUDY DESIGN: Retrospective Review. OBJECTIVE: Our goal was to investigate the incidence of cervical DDD in patients with AIS, prior to surgical intervention. SUMMARY OF BACKGROUND DATA: AIS is often associated with thoracic hypokyphosis and compensatory cervical kyphosis. In adults, cervical kyphosis is associated with DDD. Although cervical kyphosis has been reported in up to 60% AIS patients, the association with cervical DDD has not been reported...
September 11, 2023: Spine
https://read.qxmd.com/read/37694516/postoperative-discharge-to-acute-rehabilitation-or-skilled-nursing-facility-compared-to-home-does-not-reduce-hospital-readmissions-return-to-surgery-or-improve-outcomes-following-adult-spine-deformity-surgery
#12
JOURNAL ARTICLE
Shay Bess, Breton G Line, Pierce Nunley, Christopher Ames, Douglas Burton, Gregory Mundis, Robert Eastlack, Robert Hart, Munish Gupta, Eric Klineberg, Han Jo Kim, Michael Kelly, Richard Hostin, Khaled Kebaish, Virgine Lafage, Renaud Lafage, Frank Schwab, Christopher Shaffrey, Justin S Smith
STUDY DESIGN: Retrospective review of a prospective multi-center adult spinal deformity (ASD) study. OBJECTIVE: Evaluate 30-day readmissions, 90-day return to surgery, postoperative complications, and patient reported outcomes (PROs) for matched ASD patients receiving nonhome discharge (NON), including acute rehabilitation (REHAB) and skilled nursing facility (SNF), or home (HOME) discharge following ASD surgery. SUMMARY OF BACKGROUND DATA: Postoperative disposition following ASD surgery frequently involves nonhome discharge...
September 11, 2023: Spine
https://read.qxmd.com/read/37678378/hyperbaric-oxygen-therapy-inhibits-neuronal-ferroptosis-after-spinal-cord-injury-in-mice
#13
JOURNAL ARTICLE
Ruizhang Yao, Mo Liu, Fang Liang, Zhencheng Sun, Jing Yang, Junlin Zhou, Qingjun Su, Xuehua Liu
STUDY DESIGN: Basic science study investigating the Potential Molecular Mechanisms of Hyperbaric oxygen (HBO) therapy in Mice with Spinal Cord Injury(SCI). OBJECTIVE: We aimed to explore the Intrinsic Mechanisms of HBO for SCI through the lens of Ferroptosis in the subacute phase. SUMMARY OF BACKGROUND DATA: HBO has been observed to facilitate the restoration of neurologic function subsequent to SCI. Ferroptosis is a distinct cellular death mechanism that can be distinguished from apoptosis, necrosis, and autophagy...
September 7, 2023: Spine
https://read.qxmd.com/read/37678376/opportunistic-ct-based-hounsfield-units-strongly-correlate-with-biomechanical-ct-measurements-in-the-thoracolumbar-spine
#14
JOURNAL ARTICLE
Michael L Martini, Anthony L Mikula, Nikita Lakomkin, Zach Pennington, Megan C Everson, Abdelrahman M Hamouda, Mohamad Bydon, Brett Freedman, Arjun S Sebastian, Ahmad Nassr, Paul A Anderson, Francis Baffour, Kurt A Kennel, Jeremy Fogelson, Benjamin Elder
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Hounsfield units (HUs) are known to correlate with clinical outcomes, no study has evaluated how they correlate with BCT and DXA measurements. SUMMARY OF BACKGROUND: Low bone mineral density (BMD) represents a major risk factor for fracture and poor outcomes following spine surgery. Dual-energy x-ray absorptiometry (DXA) can provide regional BMD measurements but has limitations. Opportunistic HUs provide targeted BMD estimates; however, they are not formally accepted for diagnosing osteoporosis in current guidelines...
September 7, 2023: Spine
https://read.qxmd.com/read/37678375/preoperative-optimization-for-adult-spinal-deformity-surgery-a-systematic-review
#15
JOURNAL ARTICLE
Prerana Katiyar, Justin Reyes, Josephine Coury, Joseph Lombardi, Zeeshan Sardar
STUDY DESIGN: Systematic Review. OBJECTIVE: The purpose of this review is to identify modifiable risk factors in patients undergoing adult spinal deformity surgery and compile literature recommendations for preoperative optimization of these risk factors. SUMMARY OF BACKGROUND DATA: Optimization of modifiable risk factors not only benefits the patient but also lessens resource and cost burdens on the healthcare system, allowing for better quality and value-based care...
September 7, 2023: Spine
https://read.qxmd.com/read/37661834/facet-joint-morphology-and-tropism-in-adolescents-association-with-lumbar-disc-herniation-and-spondylolysis
#16
JOURNAL ARTICLE
Yoshihiro Ishihama, Fumitake Tezuka, Hiroaki Manabe, Masatoshi Morimoto, Kazuta Yamashita, Toshinori Sakai, Koichi Sairyo
STUDY DESIGN: Cross-sectional, observational. OBJECTIVE: To investigate the incidence of bidirectional lumbar facet tropism and its relationship with lumbar spine disease in adolescents. SUMMARY OF BACKGROUND DATA: There is limited information on facet joint asymmetry in the sagittal plane in adolescents. MATERIALS AND METHODS: The orientation of all lumbar facet joints was measured in the bidirectional planes on computed tomographic images for 191 patients with low back pain...
September 4, 2023: Spine
https://read.qxmd.com/read/37661823/synthetic-interbody-devices-and-traditional-bone-graft-are-associated-with-a-similar-rate-of-surgical-complications-after-1-2-level-acdfs
#17
JOURNAL ARTICLE
Geet Shukla, Abhijith V Matur, Xu Tao, Syed Khalid, Rebecca Garner, Justin Gibson, Daryn Cass, Andrew Wu, Seth Street, Julia Garcia-Vargas, Jay Mehta, Kelly Childress, Henry O Duah, Benjamin Motley, Joseph Cheng, Owoicho Adogwa
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To compare the rates of all-cause surgical complications of synthetic interbody devices versus allograft or autograft in patients undergoing 1-2 levels anterior cervical discectomy and fusion (ACDF) procedures. SUMMARY OF BACKGROUND DATA: Cervical degenerative disorders affects up to 60% of older adults in the US. Both traditional allograft or autograft and synthetic interbody devices (PEEK or titanium) are used for decompression and arthrodesis, with an increasing utilization of the latter...
September 4, 2023: Spine
https://read.qxmd.com/read/37661809/impact-of-frailty-and-cervical-radiographic-parameters-on-postoperative-dysphagia-following-anterior-cervical-spine-surgery
#18
JOURNAL ARTICLE
Tomoyuki Asada, Sumedha Singh, Omri Maayan, Pratyush Shahi, Nishtha Singh, Tejas Subramanian, Kasra Araghi, Maximilian Korsun, Olivia Tuma, Anthony Pajak, Amy Lu, Eric Mai, Yeo Eun Kim, James Dowdell, Evan D Sheha, Sravisht Iyer, Sheeraz A Qureshi
STUDY DESIGN: Retrospective review of a prospectively collected registry. OBJECTIVE: The purpose of the present study was to investigate the impact of frailty and radiographical parameters on postoperative dysphagia after anterior cervical spine surgery (ACSS). SUMMARY OF BACKGROUND DATA: There is a growing body of literature indicating an association between frailty and increased postoperative complications following various surgeries. However, few studies have investigated the relationship between frailty and postoperative dysphagia after anterior cervical spine surgery...
September 4, 2023: Spine
https://read.qxmd.com/read/37661800/no-difference-in-surgical-outcomes-between-stand-alone-devices-and-anterior-plating-for-1-2-level-anterior-cervical-discectomy-and-fusion-a-1-1-exact-matched-analysis
#19
JOURNAL ARTICLE
Xu Tao, Abhijith V Matur, Seth Street, Geet Shukla, Julia Garcia-Vargas, Jay Mehta, Kelly Childress, Henry O Duah, Justin Gibson, Daryn Cass, Andrew Wu, Benjamin Motley, Joseph Cheng, Owoicho Adogwa
STUDY DESIGN: Retrospective cohort. OBJECTIVE: Compare rates of all-cause surgical and medical complications between zero-profile (stand-alone) implants versus any graft type with anterior plate in patients undergoing 1-2 level anterior cervical discectomy and fusion (ACDF) for treatment of degenerative cervical myeloradiculopathy. SUMMARY OF BACKGROUND DATA: Degenerative cervical myeloradiculopathy is increasingly prevalent in older adults...
September 4, 2023: Spine
https://read.qxmd.com/read/37644738/quantitative-romberg-on-a-force-plate-objective-assessment-before-and-after-surgery-for-cervical-spondylotic-myelopathy
#20
JOURNAL ARTICLE
Kyle Kesler, Steven D Glassman, Jeffrey L Gum, Mladen Djurasovic, Mitchell J Campbell, Grant O Schmidt, Leah Y Carreon
STUDY DESIGN: Longitudinal Observational Cohort. OBJECTIVES: The purpose of this study was to evaluate the utility of Quantitative Romberg measurements as pre- and post-op balance outcome measures. SUMMARY OF BACKGROUND DATA: Cervical Spondylotic Myelopathy (CSM) is characterized by balance deficiencies produced by impaired proprioception. Evaluation is subjective and binary physical exam findings lack the precision to assess postoperative outcome improvement...
August 30, 2023: Spine
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