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JOURNAL ARTICLE
Ahmet Evlice, Fahreddin Över, Mehmet Balal, Elçin Ateş, Kezban Aslan-Kara
AIM: Isolated REM sleep behavior disorder (IRBD) is characterized by loss of the normal atonia of REM sleep. Patients with IRBD are at substantial risk of developing the synuclein-related neurodegenerative diseases (NDD). Few predictors of phenoconversion (from IRBD to NDD) have been identified such as age >65 years, hyposmia, constipation, elevated Epworth sleepiness scale (ESS). We aimed to detect rate and risk factors of phenoconversion. METHOD: The study designed as retrospectively...
November 23, 2023: Sleep Medicine
#2
JOURNAL ARTICLE
Ya-Wen Hsiao, Wei-Lun Lin, Yu-Hui Chou, Shin-Huei Liu, Ting-Wei Ernie Liao, Shih-Ann Chen, Li-Wei Lo
OBJECTIVES: Obstructive sleep apnea (OSA) is known to increase the risk of cardiovascular disease and inflammation plays a significant role in this process. Renal denervation (RDN) is a novel approach aimed at reducing sympathetic nervous system activity. The role of RDN in the inflammatory response to chronic OSA (COSA) is currently unclear. The main objective was to study inflammatory mechanisms in the rabbit heart with COSA and the effects of RDN. METHODS: Eighteen rabbits were randomized into three groups: sham control, COSA, and COSA-RDN...
November 21, 2023: Sleep Medicine
#3
JOURNAL ARTICLE
Amy C Reynolds, Kelly A Loffler, Nicole Grivell, Brandon Wj Brown, Robert J Adams
BACKGROUND: The combination of shift work and an unmanaged sleep disorder carries health and safety risks. Yet, diagnosis rates for sleep disorders are low in shift workers. The aim of this study was to understand the experience of sleep disorder diagnosis and treatment in shift workers, and consider patient informed solutions to improve access to health services. METHODS: Semi-structured interviews were conducted with 16 Australian shift workers with a diagnosed sleep disorder...
November 20, 2023: Sleep Medicine
#4
JOURNAL ARTICLE
Janet Jezkova, Karel Sonka, Jakub Kreisinger, Petra Prochazkova, Helena Tlaskalova-Hogenova, Sona Nevsimalova, Jitka Buskova, Radana Merkova, Tereza Dvorakova, Iva Prihodova, Simona Dostalova, Radka Roubalova
In recent years, there has been an increased interest in elucidating the influence of the gut microbiota on sleep physiology. The gut microbiota affects the central nervous system by modulating neuronal pathways through the neuroendocrine and immune system, the hypothalamus-pituitary-adrenal axis, and various metabolic pathways. The gut microbiota can also influence circadian rhythms. In this study, we observed the gut microbiota composition of patients suffering from narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia...
November 19, 2023: Sleep Medicine
#5
JOURNAL ARTICLE
Simon Hartmann, Sarah Immanuel, Scott McKane, Dominik Linz, Liborio Parrino, Mathias Baumert
STUDY OBJECTIVES: To assess the impact of transvenous phrenic nerve stimulation (TPNS) on non-rapid eye movement sleep microstructure quantified by cyclic alternating pattern (CAP) in individuals with central sleep apnea (CSA). METHODS: We analyzed baseline and 6-month follow-up overnight polysomnograms (PSG) in 134 CSA patients enrolled in the remedē System Pivotal Trial implanted with TPNS randomized (1:1) to neurostimulation (treatment group) or no stimulation (control group)...
November 19, 2023: Sleep Medicine
#6
JOURNAL ARTICLE
Sean P A Drummond, Bei Bei
Cognitive Behavioural Therapy for Insomnia is the front-line intervention for Insomnia Disorder. However, few studies have reported data on how CBT-I implementation evolves over the course of therapy or the time course of client response. This is due, in part, to no formal framework for defining stages of CBT-I. Here, we follow Spielman's original conceptualisation of Sleep Restriction Therapy (SRT) to report a two-stage model for defining stages of CBT-I, based on progression through the phases of SRT. Using data from a prior randomized clinical trial, we show the model helps identify patterns of treatment progression, which are in turn associated with baseline insomnia severity...
November 18, 2023: Sleep Medicine
#7
JOURNAL ARTICLE
Hsi-Chung Chen, Nai-Wei Hsu, Ching-Heng Lin
OBJECTIVES: This study aimed to investigate the relationship between daytime sleepiness and mortality risk among older adults. The moderating effects of sex and physical function were examined. METHODS: This 9-year follow-up study was conducted with community-dwelling individuals aged ≥65 years. Daytime sleepiness was evaluated using the Epworth Sleepiness Scale (ESS). Exploratory factor analysis (EFA) was used to examine the ESS factors. Handgrip strength was measured to assess physical function, and the highest quartile was defined as good muscle power...
November 18, 2023: Sleep Medicine
#8
JOURNAL ARTICLE
Bin Yu, Yao Fu, Shu Dong, Jan D Reinhardt, Peng Jia, Shujuan Yang
BACKGROUND: Mental health issues are severe public health problems, inevitably affected by, also affecting, sleep. We used network analysis to estimate the relationship among various aspects of sleep and mental health simultaneously, and identify potential action points for improving sleep and mental health among employees. METHODS: We used data from the baseline survey of the Chinese Cohort of Working Adults that recruited 31,105 employees between October 1st and December 31st, 2021...
November 18, 2023: Sleep Medicine
#9
JOURNAL ARTICLE
Zhihua Huang, Anqi Duan, Zhihui Zhao, Qing Zhao, Yi Zhang, Xin Li, Sicheng Zhang, Luyang Gao, Chenhong An, Qin Luo, Zhihong Liu
BACKGROUND: Sleep-disordered breathing (SDB) is common among pulmonary arterial hypertension (PAH) patients and has been associated with unfavorable outcomes. This study aims to cluster overnight cardiorespiratory signals to investigate PAH phenotypes and examining their prognostic implications. METHODS: In this retrospective cohort study, we recruited consecutive PAH patients who underwent right heart catheterization and nocturnal cardiorespiratory polygraphy to evaluate SDB...
November 13, 2023: Sleep Medicine
#10
JOURNAL ARTICLE
C González-Merino, E Martínez-Cayuelas, A Ladrón-Guevara, R López-Gómez, C Esteban-Amarilla, G Del-Río Camacho
PURPOSE: Periodic limb movements (PLMs) can be found isolated or related to other sleep disorders, as Obstructive Sleep Apnea (OSA). Nevertheless, this association was described before the proposal for modification of the World Association of Sleep Medicine (WASM), which incorporated major changes modifying the definition of respiratory-related leg movements (RRLM) so that the relationship between OSA and PLM could be affected. METHODS: A total of 131 PSG were studied (children with ages from 5 to 12 years old), all referred because of a suspicion of sleep-disordered breathing (65 children were diagnosed of OSA, and 66 presented snoring but no sleep apnea)...
November 11, 2023: Sleep Medicine
#11
JOURNAL ARTICLE
Annika M Myers, Megan E Rech, Bengi Baran, Cara Palmer, Dimitrios Mylonas, Candice A Alfano
BACKGROUND: While connections between children's sleep and their daytime functioning are well established, less is known about the microstructural features of sleep that support emotional wellbeing. Investigating these relationships in healthy children may provide insight into adaptive emotional development. We therefore examined associations between non-rapid eye movement (N2) sleep spindles and both state- and trait-based measures of emotion. METHODS: A sample of 30 children (7-11 years) without psychiatric disorders completed a baseline assessment, one night of at-home polysomnography (PSG), and an in-lab emotional state assessment the next day including self-reported arousal in response to affective images...
November 11, 2023: Sleep Medicine
#12
JOURNAL ARTICLE
Mauro Manconi, Linda C van der Gaag, Francesca Mangili, Corrado Garbazza, Silvia Riccardi, Christian Cajochen, Susanna Mondini, Francesca Furia, Elena Zambrelli, Simone Baiardi, Alessandra Giordano, Nicola Rizzo, Cristina Fonti, Elsa Viora, Armando D'Agostino, Alessandro Cicolin, Fabio Cirignotta, Daniele Aquilino, Alessandra Barassi, Renata Del Giudice, Giulia Fior, Orsola Gambini, Barbara Giordano, Alma Martini, Chiara Serrati, Rossana Stefanelli, Silvio Scarone, Mariapaola Canevini, Valentina Fanti, Hans-Christian Stein, Anna Maria Marconi, Erica Raimondo, Emanuela Viglietta, Rossella Santoro, Giuliana Simonazzi, Alessandra Bianconcini, Francesco Meani, Nicoletta Piazza, Filippos Filippakos, Thomas Gyr
OBJECTIVE: to prospectively assess sleep and sleep disorders during pregnancy and postpartum in a large cohort of women. METHODS: multicenter prospective Life-ON study, recruiting consecutive pregnant women at a gestational age between 10 and 15 weeks, from the local gynecological departments. The study included home polysomnography performed between the 23rd and 25th week of pregnancy and sleep-related questionnaires at 9 points in time during pregnancy and 6 months postpartum...
November 11, 2023: Sleep Medicine
#13
JOURNAL ARTICLE
Xiao Tan, Mirjam Ljunggren, Lena Kilander, Christian Benedict, Eva Lindberg
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) during rapid eye movement (REM) sleep is often characterized with more frequent and lengthy breathing events and greater oxygen desaturation than during other sleep stages. Current evidence suggests an association between OSA and cognitive decline, however whether OSA during REM sleep plays a vital role in this link is understudied. METHODS: A cross-sectional sample of 728 men and women (aged 59.1 ± 11...
November 11, 2023: Sleep Medicine
#14
JOURNAL ARTICLE
Devin L Brown, Joseph W Burns, Madeline Kwicklis, Xu Shi, Ronald D Chervin, Erin Case, Lewis B Morgenstern, Virend K Somers, Lynda D Lisabeth
OBJECTIVE/BACKGROUND: Standard measures of sleep-disordered breathing (SDB) that rely on count data may not sufficiently capture SDB severity or reflect downstream consequences of SDB. We hypothesized that novel metrics derived from pulse rate, oxygen saturation, and nasal pressure would be associated with stroke outcomes. PATIENTS/METHODS: Shortly after ischemic stroke, participants in a population-based study were offered ApneaLink Plus testing. Signal analysis was used to generate 166 metrics from the nasal pressure cannula and finger probe, categorized as: autonomic (based on pulse rate variability), oximetry-derived, nasal pressure-derived, and mixed oxygen and nasal pressure-derived measures...
November 10, 2023: Sleep Medicine
#15
JOURNAL ARTICLE
Yudan Lv, Yujun Wen, Ramalingam Vetrivelan, Jun Lu
INTRODUCTION: The basal forebrain (BF) and the medial septum (MS) respectively drive neuronal activity of cerebral cortex and hippocampus (HPC) in sleep-wake cycle. Our previous studies of lesions and neuronal circuit tracing have shown that the pontine parabrachial nucleus (PB) projections to the BF and MS may be a key circuit for cortical and HPC arousal. AIMS: This study aims to demonstrate that PB projections to the BF and MS activate the cerebral cortex and HPC...
November 10, 2023: Sleep Medicine
#16
JOURNAL ARTICLE
Masayoshi Yoshida, Hilmi R Dajani, Shin-Ichi Ando, Shuji Shimizu, Miodrag Bolic, Voicu Groza
BACKGROUND: Noninvasive positive pressure ventilation (NIPPV) has been established as an effective treatment for heart failure. Positive airway pressure such as continuous positive airway pressure (CPAP) increases cardiac output (CO) in some patients but decreases it in others. However, the mechanism behind such unpredictable responses remains undetermined. METHODS AND RESULTS: We measured hemodynamic parameters of 38 cases using Swan-Ganz catheter before and after CPAP in chronic heart failure status...
November 10, 2023: Sleep Medicine
#17
JOURNAL ARTICLE
Seolbin Han, Dae-Kwang Kim, Sang-Eun Jun, Nahyun Kim
OBJECTIVES: Mitochondria contribute to various compromised health, yet the association between sleep and mitochondria remains unclear. This study investigated the association between sleep quality and mitochondrial function in healthy middle-aged adults in the Republic of Korea. METHOD: This cross-sectional study recruited 238 middle-aged adults using convenience sampling. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Mitochondrial function, represented by mitochondrial DNA copy number (mtDNAcn), was measured using real-time quantitative polymerase chain reaction on peripheral blood leukocytes...
November 10, 2023: Sleep Medicine
#18
JOURNAL ARTICLE
Yanmin Tao, Jingsong Luo, Yaxin Xu, Hongyan Wang, Jing Tian, Shenbi Yang, Kexin Yu, Sihan Peng, Xiangeng Zhang
BACKGROUND: Observational findings suggest that patients with narcolepsy are at higher risk for cardiovascular diseases (CVDs), but the potential causal relationship between narcolepsy and CVDs is unclear. Therefore, Mendelian randomization (MR) was used to explore the association between narcolepsy and CVDs. METHODS: Summary statistics related to narcolepsy, coronary artery disease (CAD), myocardial infarction (MI), heart failure (HF), any stroke (AS), and any ischemic stroke (AIS) were extracted from the public database of relevant published genome-wide association studies (GWAS)...
November 10, 2023: Sleep Medicine
#19
JOURNAL ARTICLE
Hung Youl Seok, Yong Won Cho
OBJECTIVES: Although some studies have examined the impact of short-term dopamine agonist treatment on altered central sensory processing in patients with restless legs syndrome (RLS), there is a scarcity of research investigating the effect of long-term treatment with these drugs. The aim of this study is to investigate the long-term impact of dopamine agonist treatment on altered central sensory processing in RLS patients using current perception threshold (CPT) testing. METHODS: We conducted a study of 24 RLS patients, measuring their CPT values before and after dopamine agonist treatment for at least 2 months...
November 10, 2023: Sleep Medicine
#20
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
November 8, 2023: Sleep Medicine
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