Fikir M Mesfin, Krishna Manohar, Chelsea E Hunter, W Christopher Shelley, John P Brokaw, Jianyun Liu, Minglin Ma, Troy A Markel
Stem cell research and the use of stem cells in therapy have seen tremendous growth in the last two decades. Neonatal intestinal disorders such as necrotizing enterocolitis, Hirschsprung disease, and gastroschisis have high morbidity and mortality and limited treatment options with varying success rates. Stem cells have been used in several pre-clinical studies to address various neonatal disorders with promising results. Stem cell and patient population selection, timing of therapy, as well as safety and quality control are some of the challenges that must be addressed prior to the widespread clinical application of stem cells...
March 12, 2023: Seminars in Perinatology