Javier Arredondo Montero, Andrea Torres López, Guillermina Hurtado Ilzarbe, Giuseppa Antona, Raquel Ros Briones, Natalia López-Andrés, Nerea Martín-Calvo
INTRODUCTION: Scientific literature regarding the characterization of lymphocyte subpopulations of the cecal appendix is sparse, with few precedents limited to immunohistochemical techniques. METHODS: We conducted a prospective pilot study to characterize lymphocyte subpopulations of the cecal appendix in children. Participants were divided into three groups: (1) patients without histological acute appendiceal inflammation, (2) patients with histological uncomplicated acute appendicitis, and (3) patients with histological complicated acute appendicitis (gangrenous, perforated)...
September 22, 2023: Pediatric Surgery International
Satoshi Umeda, Masayuki Yoshida, Sayaka Matsumoto, Takaaki Sakai, Yuki Noguchi, Rei Matsuura, Masahiro Zenitani, Noriaki Usui
PURPOSE: This study aimed to investigate the incidence and clinical factors associated with undescended testes (UDT) in patients with congenital diaphragmatic hernia (CDH). METHODS: We retrospectively reviewed the incidence of UDT in male neonates admitted to our institution and underwent surgery for CDH between January 2006 and December 2022. Patients were divided into two groups based on the presence or absence of UDT, and risk factors for UDT were compared between the two groups...
September 17, 2023: Pediatric Surgery International
Gizem Guner Ozenen, Aybuke Akaslan Kara, Arife Ozer, Pelin Kacar, Deniz Ergun, Aysenur Aydin, Incinur Genisol Ataman, Kamer Polatdemir, Ayse Demet Payza, Yelda Sorguc, Akgun Oral, Nuri Bayram, Ilker Devrim
PURPOSE: We aimed to evaluate the demographic characteristics of children with perianal abscess, distribution of microbiological etiology, antibiotic susceptibility, and identify the effectiveness and coverage of antibiotics due to culture results. METHODS: A retrospective study was designed to evaluate pediatric patients with perianal abscesses between January 2013 and December 2022. RESULTS: A total of 197 episodes in 135 patients were evaluated...
September 11, 2023: Pediatric Surgery International
Masakazu Murakami, Shun Onishi, Koji Yamada, Katsuhiro Ogawa, Shinichiro Yokoyama, Yo Kurashima, Go Miyano, Tetsuya Ishimaru, Hiroshi Kawashima, Hiroo Uchida, Atsuyuki Yamataka, Hiroomi Okuyama, Satoshi Ieiri
PURPOSE: To ensure the safe spread of pediatric endoscopic surgery, it is essential to build a training curriculum, and a survey of the current situation in Japan is necessary. The present study assessed an efficient training curriculum by clarifying instructor class pediatric surgeons' experiences, including autonomy when performing advanced endoscopic surgeries. METHODS: An online nationwide questionnaire survey was conducted among pediatric surgeons who had Endoscopic Surgical Skill Qualification (ESSQ) and board-certified instructors who had skills comparable to ESSQ...
September 9, 2023: Pediatric Surgery International
Linnea Högberg, Sanni Värelä, Magnus Anderberg, Martin Salö
PURPOSE: Pelvoureteric junction obstruction (UPJO) is a common cause of hydronephrosis in children but no previous studies have evaluated differences between boys and girls operated with pyeloplasty. This study aimed to evaluate potential differences between sexes in children operated with pyeloplasty for PUJO in terms of presentation, surgery, and long-term results. METHODS: Data was retrospectively collected from all children operated on with pyeloplasty between January 2002 and December 2020...
September 8, 2023: Pediatric Surgery International
Daisuke Ishii, Yuka Kumata, Seiya Ishii, Keita Motoki, Hisayuki Miyagi
PURPOSE: Since pediatric stomas are often temporary, their creation, management, and closure should be simple, with minimal complications and excellent cosmetic results. We began employing umbilical stomas in 2000. This study aimed to characterize the ingenuity and utility of umbilical stomas and provide a quantitative evaluation of their cosmetic outcomes. METHODS: We examined cases of stoma construction and closure surgery performed in our department from January 2000 to December 2022...
September 7, 2023: Pediatric Surgery International
Devon Pace, Shale J Mack, Kesavan Sadacharam, Robert S Lang, Brian Burke, Keith Fishlock, Loren Berman
PURPOSE: This study analyzes the implementation of the routine use of quadratus lumborum blocks (QLBs) on postoperative pain and opioid consumption among children undergoing laparoscopic appendectomy compared to those not receiving regional anesthesia. METHODS: Children undergoing laparoscopic appendectomy within a multi-hospital children's healthcare system were retrospectively reviewed from 2017 to 2021. Patients were stratified by appendicitis type (uncomplicated vs...
September 7, 2023: Pediatric Surgery International
Qiwen Yang, Fuwen Wang, Zhaofei Wang, Jiajun Guo, Tingjin Chang, Baligen Dalielihan, Ge Yang, Chuzhao Lei, Ruihua Dang
PURPOSE: The aim of this study is to use RNA sequencing and RT-qPCR to identify the main susceptibility genes linked to the occurrence and development of Hirschsprung disease in the colonic tissues of EDNRBm1yzcm and wild mice. METHODS: RNA was extracted from colon tissues of 3 mutant homozygous mice and 3 wild mice. RNA degradation, contamination concentration, and integrity were then measured. The extracted RNA was then sequenced using the Illumina platform. The obtained sequence data are filtered to ensure data quality and compared to the reference genome for further analysis...
September 7, 2023: Pediatric Surgery International
Ayaka Nagano, Toshio Harumatsu, Koshiro Sugita, Yumiko Iwamoto, Masato Ogata, Lynne Takada, Nanako Nishida, Chihiro Kedoin, Masakazu Murakami, Keisuke Yano, Shun Onishi, Koji Yamada, Waka Yamada, Takafumi Kawano, Mitsuru Muto, Tatsuru Kaji, Satoshi Ieiri
PURPOSE: Anovestibular fistula (AVF) is the most common type of ARM in female patients. The present study investigated changes over time in the postoperative defecation function of female patients with AVF. METHODS: Patient data were collected from 1984 to 2021. Eighty-eight female patients with AVF were enrolled. Patients' characteristics and the long-term outcome of defecation function were reviewed and analyzed retrospectively. The bowel function was evaluated according to the Japan Society of ARM Study Group evacuation score (ES)...
September 7, 2023: Pediatric Surgery International
Miao Sun, Chengjun Yu, Jie Zhao, Maolin Liu, Yan Liu, Rong Han, Long Chen, Shengde Wu
To evaluate the safety and effectiveness of robotic-assisted laparoscopic pyeloplasty (RALP) for treating pediatric ureteropelvic junction obstruction through an extensive comparison of RALP, open pyeloplasty (OP) and laparoscopic pyeloplasty (LP). We conducted a comprehensive search of the following databases: PubMed, Excerpta Medica Database, Cochrane Library, Web of Science database, China National Knowledge Infrastructure, WanFang Data, and China Biology Medical Disc. Baseline data were compared, the sources of heterogeneity were assessed, and publication biases were detected...
September 6, 2023: Pediatric Surgery International
Yuko Kamata, Yuki Mizuno, Kentaro Okamoto, Shota Okamoto, Yoshifumi Ito, Aya Nishigata
PURPOSE: Tunneled central venous catheters (TCVs) are commonly used for pediatric chemotherapy. Recently, peripherally inserted central catheters (PICCs) have been used instead. Although PICC has the advantages of simpler insertion and fewer severe complications, there is little information on the efficacy of PICC compared to TCV in pediatric chemotherapy. METHODS: Patients, aged younger than 18 years, with primary malignancy who received chemotherapy with PICC or TCV at our institution from December 2007 to August 2022 were included in the study...
September 6, 2023: Pediatric Surgery International
H Y Lo, K F K Fung, F Yam, Y Leung, A Liu, K K Cheng, D Cho, E Y L Kan, N Chao
INTRODUCTION: Central venous catheter (CVC) placement is commonly performed in children. We aim to develop simple formulas to predict CVC intravascular length to minimise radiation exposure associated with the procedure. METHODS: 124 paediatric patients who received tunnelled neck CVCs and subsequent CT thorax at Hong Kong Children's Hospital from January 2020 to July 2022 were reviewed retrospectively. Formula development cohorts were subdivided by insertion sites-9 right external jugular vein (REJV), 41 right internal jugular vein (RIJV), 14 left external jugular vein (LEJV), 10 left internal jugular vein (LIJV)...
September 5, 2023: Pediatric Surgery International
Yunosuke Kawaguchi, Keita Terui, Ayako Takenouchi, Shugo Komatsu, Takeshi Saito, Tomoro Hishiki
PURPOSE: This study aimed to elucidate the difficulties faced by adult native liver survivors with biliary atresia (BA) in Japan. METHODS: A single-center, retrospective, observational study of 57 adult patients with BA was conducted. The clinical course of BA was compared between native liver survivors and non-survivors who reached adulthood. Indications and outcomes of liver transplantation (LT) among non-survivors were assessed. RESULTS: A significantly larger portion of non-survivors (n = 10) met the criteria for LT (p < 0...
September 5, 2023: Pediatric Surgery International
Takuya Maeda, Jiahui Liu, Hiroo Uchida, Hizuru Amano, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Satoshi Makita, Aitaro Takimoto, Shunya Takada, Yoichi Nakagawa, Akihiro Gouda, Yaohui Guo, Akinari Hinoki
PURPOSE: This study aimed to clarify the validity of robot-assisted surgery (RAS) for pediatric patients with congenital biliary dilatation (CBD). METHODS: We retrospectively compared RAS and laparoscopic surgery (LS) for pediatric CBD performed by the same certified surgeon between 2016 and 2022. RESULTS: We included 6 RAS and 12 LS cases in this study. One case of RAS with laparotomy was excluded from the analysis. The patients in the two groups had comparable ages and body weights...
September 3, 2023: Pediatric Surgery International
Juma Obayashi, Koji Fukumoto, Masaya Yamoto, Hiromu Miyake, Akiyoshi Nomura, Risa Kanai, Yuri Nemoto, Takafumi Tsukui
PURPOSE: In the event of failed tracheostomy decannulation, patients might have a tragic course of events. We retrospectively evaluated our stepwise tracheostomy decannulation program and examined its safety. METHODS: A 12-year retrospective study of pediatric patients was conducted. The decannulation program was performed on patients who had airway patency by laryngobronchoscopy and whose cannula could be capped during the day. A stepwise decannulation program was performed: continuous 48-h capping trial during hospitalization (Phase 1), removal of the tracheostomy tube for 48 h during hospitalization (Phase 2), and outpatient observation (Phase 3)...
September 2, 2023: Pediatric Surgery International
Satoru Oita, Takeshi Saito, Rei Hashimoto, Takashi Fumita, Yoshio Katsumata, Keita Terui, Shugo Komatsu, Ayako Takenouchi, Jun-Ichiro Ikeda, Tomoro Hishiki
PURPOSE: Immunological abnormalities have been hypothesized as a pathogenesis of biliary atresia (BA). We previously investigated the frequency and function of circulating regulatory T-cells (Tregs) and reported no differences compared to controls. However, the local Treg profile remains uncertain. We aimed to investigate the frequency of Tregs in BA liver tissues. METHODS: The number of lymphocytes, CD4+ cells, and CD4+ FOXP3+ Tregs infiltrating the portal tract and the percentage of Tregs among CD4+ cells of BA and control patients were visually counted...
September 1, 2023: Pediatric Surgery International
Pablo Laje, Benjamin Smood, Christopher Smith, Erin Pinto, Ganesh Krishnamurthy, Dalal Taha, Yoav Dori, Katsuhide Maeda
PURPOSE: Central lymphatic obstructions are associated with anasarca and high mortality. We hypothesized that opening dilated cutaneous lymphatic channels by creating a lymphocutaneous fistula (LCF) would decompress the lymphatic circulation and improve anasarca. METHODS: We reviewed all patients that had at least one LCF created between 9/2019 and 12/2022. LCF efficacy was determined by changes in weight, urine/diuresis, ventilation, and clinical status. RESULTS: We created eleven LCFs in four infants...
August 31, 2023: Pediatric Surgery International
Caner Isbir, Şener Çolak, Lara Taşan, Hakan Taşkınlar
PURPOSE: Ureteral stents can cause lower urinary tract problems such as stent-related irritative symptoms and urinary tract infections. This study aimed to determine the lower urinary tract effects of ureteral stent length and intravesical position in children. METHODS: Patients who underwent double-J stenting after urological procedures between January 2017 and January 2022 were included in the study. The patients were assessed in terms of age, irritative symptoms, urinary tract infections, and stent length...
August 31, 2023: Pediatric Surgery International
Mario Cuesta Argos, Isabel Casal Beloy, Marta Pilar Martín Gimenez, Albert Pasten González, Rosalía Carrasco Torrents, Lucas Krauel
No abstract text is available yet for this article.
August 31, 2023: Pediatric Surgery International
Li-Yu Yang, Chia-Man Chou, Sheng-Yang Huang, Hou-Chuan Chen
BACKGROUND: Vesicoureteral junction (VUJ) obstruction after Deflux® subureteral injection for vesicoureteral reflux (VUR) is rare and minimally invasive management has not been reported. This work investigated the patients who underwent Deflux® injection for VUR and identified those with subsequent VUJ obstruction. METHODS: Medical records of matched patients from October 2003 to March 2022 were reviewed, and parameters were retrospectively studied. All patients underwent Deflux® injection...
August 29, 2023: Pediatric Surgery International
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