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Journals Pediatric Infectious Disease J...

Pediatric Infectious Disease Journal

https://read.qxmd.com/read/36929884/neonatal-group-b-streptococcal-infection-in-australia-a-case-control-study
#1
JOURNAL ARTICLE
Marianne Yanni, Michael Stark, Laura Francis, Joshua R Francis, Mark McMillan, Rob Baird, Paul T Heath, Alex Gordon, James Riccardione, Angela Wilson, Rebecca Lee, Kathrina Chooi, Olivia-Paris Quinn, Helen S Marshall
BACKGROUND: To determine maternal and neonatal risk factors for, and incidence of, neonatal early-onset group B streptococcus (EOGBS) and late-onset (LOGBS) infection in South Australia (SA) and the Northern Territory (NT). METHODS: A case-control study with 2:1 matched controls to cases. The study included tertiary hospitals in South Australia and the Northern Territory, Australia. Retrospective data were collected from a 16-year epoch (2000-2015). RESULTS: Of a total of 188 clinically suspected or confirmed cases, 139 were confirmed, of which 56...
March 16, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36917035/decreased-hepatic-steatosis-in-south-african-adolescents-with-perinatal-hiv-switching-to-dolutegravir-containing-regimens
#2
JOURNAL ARTICLE
Penelope C Rose, Etienne De la Rey Nel, Mark F Cotton, Kennedy Otwombe, Sara H Browne, Lisa J Frigati, Helena Rabie, Steve Innes
BACKGROUND: Although dolutegravir (DTG) has a favorable metabolic profile, it has been linked to excess weight gain. We evaluated changes in hepatic steatosis in adolescents with perinatally acquired HIV switching to DTG-containing antiretroviral therapy (ART). METHODS: Virologically suppressed adolescents switched to dolutegravir for a minimum of 4 months or on unchanged ART (84% protease inhibitor) were assessed prospectively with anthropometry, transient elastography with controlled attenuation parameter (CAP) and fasting metabolic profiles...
March 14, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36917023/expanding-the-differential-for-alternative-diagnoses-in-the-workup-of-multisystem-inflammatory-syndrome-in-children
#3
JOURNAL ARTICLE
Kelli Kaneta, Sanchi Malhotra, Jacqueline Szmuszkovicz, Sindhu Mohandas, Sarah White, Susan Wu
BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C) is a rare inflammatory syndrome associated with SARS-CoV-2 infection. Children are increasingly admitted for MIS-C evaluation, but instead found to have alternative diagnoses. METHODS: Retrospective study of all pediatric patients <21 years of age hospitalized between August 1, 2020, and July 31, 2021, with clinical concern for MIS-C at the time of presentation were identified through use of an institutional computerized MIS-C order entry set...
March 10, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36917019/association-between-nudt15-r139c-genotype-and-neutropenia-during-antiviral-therapy-in-patients-with-congenital-cytomegalovirus-infection
#4
JOURNAL ARTICLE
Makoto Yamaguchi, Ken-Ichi Iwata, Yuto Fukuda, Kazunori Haruta, Takako Suzuki, Yuka Torii, Yoshinori Ito, Jun-Ichi Kawada
No abstract text is available yet for this article.
March 10, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36917032/development-of-the-anaerobic-microbiome-in-the-infant-gut
#5
JOURNAL ARTICLE
Howard Faden
Ninety-five percent of gut microbiota are anaerobes and vary according to age and diet. Complex carbohydrates in human milk enhance the growth of Bifidobacterium and Bacteroides in the first year. Complex carbohydrates in solid foods enhance the growth of Bacteroides and Clostridium in the second year. Short-chain fatty acids produced by Akkermansia and Faecalibacterium may reduce obesity, diabetes and IBD.
March 8, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36917029/a-hypothesis-generating-prospective-longitudinal-study-to-assess-the-relative-contribution-of-common-respiratory-viruses-to-severe-lower-respiratory-infections-in-young-children
#6
JOURNAL ARTICLE
Shalom Ben-Shimol, Octavio Ramilo, Amy L Leber, Bart Adriaan van der Beek, Kathy Everhart, Sara Mertz, Asuncion Mejias, Ron Dagan
BACKGROUND: Respiratory viruses such as respiratory syncytial virus (RSV), influenza, parainfluenza and human metapneumovirus are well-established etiologies of acute lower respiratory tract infections (ALRIs; LRI-viruses). In contrast, adenovirus (AdV), rhinovirus/enterovirus (RV/EV) and seasonal human coronaviruses (CoV), collectively termed AdV/RV/CoV, are detected both in healthy children and children with ALRI. METHODS: The methods include a prospective longitudinal case-control study, assessing the prevalence of LRI-viruses versus AdV/RV/CoV in ALRI [community-acquired alveolar pneumonia (CAAP) and bronchiolitis] during hospitalization (visit 1), 7-14 days (visit 2) and 28-35 days (visit 3) in 2-17-month-old children...
March 8, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36917025/blalock-taussig-shunt-blockage-caused-by-small-colony-variants-of-enterococcus-faecalis
#7
JOURNAL ARTICLE
Toru Higuchi, Eiki Ogawa, Toshihiko Okumura, Mana Yamamoto, Naoko Muramatsu, Kenta Ito
No abstract text is available yet for this article.
March 7, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36916863/clinical-and-laboratory-characteristics-of-hemophagocytic-lymphohistiocytosis-in-children-with-severe-dengue-during-the-2019-2020-outbreak-in-southern-colombia
#8
JOURNAL ARTICLE
Valeria Camila Restrepo Arias, Doris M Salgado García, Angela M Merchán-Galvis, Carlos F Narváez
BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is characterized by uncontrolled activation of inflammatory cells and an exaggerated release of cytokines. It can be triggered by different factors, including viruses, such as dengue. The objective of this study was to characterize the clinical and laboratory profiles of children with severe dengue and HLH, and to identify the risk factors for this clinical complication. METHODS: An analytical study was conducted in children with severe dengue who were treated in an intensive care unit between January 2019 and March 2020...
March 3, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36916862/boosting-of-voriconazole-levels-with-omeprazole-a-cyp450-2c19-inhibitor
#9
JOURNAL ARTICLE
Alice J Hsu, Carlton K K Lee, John McAteer, Sean X Zhang, Pranita D Tamma
Children metabolize voriconazole faster than adults and require higher weight-based doses and more frequent administration to achieve therapeutic troughs. We report a case of a 4-year-old girl with disseminated fusariosis with persistently undetectable voriconazole troughs. Omeprazole was added as a CYP2C19-inhibitor to increase voriconazole concentrations. This case highlights the role of omeprazole for voriconazole boosting in a child.
March 3, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36916867/lessons-from-the-wrong-isolation-policy-violating-human-rights-for-leprosy-in-japan
#10
JOURNAL ARTICLE
Yuho Horikoshi, Michiko Toizumi
Leprosy, caused by Mycobacterium leprae, is one of the so-called "neglected tropical diseases" and is found today mainly in Africa, Asia and South America. Although oral antibiotics capable of curing leprosy are now available, the disease is still misunderstood and feared by the public because of the unsightly deformities that it may cause. In Japan, leprosy has been present since the 8th century and was regarded as a hereditary disease; people avoided marrying into a family with a member affected by leprosy...
March 2, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36916866/severe-bacterial-infection-initially-misdiagnosed-as-mis-c-caution-needed
#11
JOURNAL ARTICLE
Anna Stanzelova, Agathe Debray, Slimane Allali, Zahra Belhadjer, Muhamed-Kheir Taha, Jérémie F Cohen, Julie Toubiana
Working in the era of the novel coronavirus disease 2019 can predispose to cognitive bias. We present a case of life-threatening bacterial infection misdiagnosed as multisystem inflammatory syndrome in children. While multisystem inflammatory syndrome in children-related myocardial dysfunction is now a well-recognized complication of coronavirus disease 2019, a rigorous differential diagnosis approach, notably for infectious etiologies, is paramount.
March 2, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36916865/comparison-of-clinical-characteristics-of-children-infected-with-coronavirus-disease-2019-between-omicron-variant-ba-5-and-ba-1-ba-2-in-japan
#12
JOURNAL ARTICLE
Tatsuki Ikuse, Yuta Aizawa, Takayuki Yamanaka, Satoshi Hasegawa, Takanori Hayashi, Miyako Kon, Tsutomu Tamura, Akihiko Saitoh
BACKGROUND: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has dramatically altered the clinical profile of pediatric coronavirus disease 2019 (COVID-19). In Japan, we experienced a pandemic of omicron subvariant BA.1/BA.2 from January through June 2022. However, after the emergence of BA.5 in early July 2022, the number of children hospitalized with COVID-19 increased dramatically in Japan. METHODS: We collected data on monthly numbers of cases and clinical characteristics of hospitalized children with COVID-19 in 13 hospitals, the total number of pediatric COVID-19 cases, and COVID-19 vaccination rates in Niigata, Japan, for the period from January 2020 through August 2022...
March 2, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36916856/antibody-persistence-after-primary-sars-cov-2-infection-and-protection-against-future-variants-including-omicron-in-adolescents-national-prospective-cohort-study
#13
JOURNAL ARTICLE
Felicity Aiano, Georgina Ireland, Frances Baawuah, Joanne Beckmann, Ifeanyichukwu O Okike, Shazaad Ahmad, Joanna Garstang, Andrew J Brent, Bernadette Brent, Ray Borrow, Ezra Linley, Sammy Ho, Christine Carr, Maria Zambon, John Poh, Lenesha Warrener, Gayatri Amirthalingam, Kevin E Brown, Mary E Ramsay, Katja Hoschler, Shamez N Ladhani
BACKGROUND: Antibodies are a measure of immunity after primary infection, which may help protect against further SARS-CoV-2 infections. They may also provide some cross-protection against SARS-CoV-2 variants. There are limited data on antibody persistence and, especially, cross-reactivity against different SARS-CoV-2 variants after primary infection in children. METHODS: We initiated enhanced surveillance in 18 secondary schools to monitor SARS-CoV-2 infection and transmission in September 2020...
March 1, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36854127/outcomes-in-pediatric-central-line-associated-bloodstream-infections-treated-with-antimicrobial-locks-a-14-year-retrospective-analysis
#14
JOURNAL ARTICLE
Lorne W Walker, Shyam Visweswaran, Andrew J Nowalk
BACKGROUND: Central line-associated bloodstream infections (CLABSI) are the most common healthcare-associated infection in children. Antimicrobial lock therapy (ALT) is a recommended component of CLABSI treatment; however, studies characterizing pediatric ALT-based CLABSI therapy are few. METHODS: All CLABSI treated with ALT at a single tertiary-care pediatric hospital for years 2004-2018 were identified by retrospective chart review and demographic, clinical, microbiological and pharmacy data were extracted...
February 24, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36854121/consecutive-seven-serious-cases-with-invasive-group-a-streptococcal-infections-at-december-2022-january-2023
#15
JOURNAL ARTICLE
Mahmut Can Kizil, Yalcin Kara, Gurkan Bozan, Surhan Arda, Gul Durmaz, Omer Kilic, Ener Cagri Dinleyici
No abstract text is available yet for this article.
February 24, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36854119/clinical-outcomes-of-covid-19-in-newborns-and-infants-a-multicenter-experience-of-576-cases
#16
JOURNAL ARTICLE
Fatima A Al Dhaheri, Huda El Dannan, Muhammad Jawad Hashim, Shooq Alshehi, Farah Al-Jburi, Aisha Antali, Noora Al Jasmi, Shaima Al Khouri, Mohamad Al Hajjar, Thikra Abbas, Ahmed ElGhoudi, Moza Al Hassani
BACKGROUND: The literature describing clinical presentation, disease course and outcomes of SARS-COV-2 in infants remains scarce. METHODS: We conducted a retrospective study across 2 major pediatric referral centers evaluating the demographics, clinical and laboratory characteristics, management and outcomes of COVID-19 among newborns and infants in the United Arab Emirates (UAE). Clinical and biochemical markers were evaluated for their accuracy in predicting intensive care unit (ICU) transfer and death...
February 24, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36854129/comprehensive-review-of-emergence-and-virology-of-tickborne-bourbon-virus-in-the-united-states
#17
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
February 22, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36854122/risk-factors-for-carbapenem-resistant-pseudomonas-aeruginosa-infection-in-children-correspondence
#18
JOURNAL ARTICLE
Allison Chan, Peter F Rebeiro, Jonathan Schmitz
No abstract text is available yet for this article.
February 22, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36854120/pseudomonas-bacteremia-in-children-clinical-and-microbiologic-features-and-risk-factors-of-mortality-a-retrospective-cohort-study
#19
JOURNAL ARTICLE
Rozeen Abu Shqara, Imad Kassis, Ranaa Damouni Shalabi, Halima Dabaja Younis
BACKGROUND: Pseudomonas bacteremia is most commonly acquired in hospital. The aim of this study was to investigate the clinical features and antibiotic susceptibility, mortality rate and risk factors of mortality in children with Pseudomonas bacteremia. METHODS: A retrospective cohort study that included children 18 years of age or younger admitted to a tertiary hospital with Pseudomonas bacteremia between 2005 and 2020. RESULTS: A total of 196 patients with Pseudomonas bacteremia were identified...
February 22, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36854117/vaccine-decision-making-in-a-time-of-conflicting-recommendations-a-call-to-go-beyond-politics
#20
JOURNAL ARTICLE
Daniel A Salmon, Stanley Plotkin, Ann Marie Navar
No abstract text is available yet for this article.
February 22, 2023: Pediatric Infectious Disease Journal
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