journal
Journals Pediatric Infectious Disease J...

Pediatric Infectious Disease Journal

https://read.qxmd.com/read/38986011/bone-and-joint-infections-in-children-with-sickle-cell-disease-in-french-guiana-a-13-year-retrospective-multicenter-review
#1
JOURNAL ARTICLE
Apolline Furgier, Juliette Goutines, Succes Dobian, Magaly Zappa, Magalie Demar, Nadjia Aigoun, Bruno Oubda, Albert Faye, Narcisse Elenga, Lindsay Osei
INTRODUCTION: Sickle cell disease (SCD) is a genetic disorder with a high infectious morbidity and mortality and a heterogeneous distribution in France. One of the challenges is to differentiate a bone and joint infection (BJI) from a vaso-occlusive crisis. This challenge is particularly prevalent in French Guiana, an overseas territory with the highest incidence of SCD in France. The aim of this study was to describe the epidemiology of BJI in children with SCD in French Guiana. METHOD: This was a retrospective multicentric descriptive study of SCD patients living in French Guiana aged under 18 and diagnosed with a BJI between 2010 and 2022...
July 9, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38986007/lock-therapy-for-treatment-and-prevention-of-catheter-related-infections
#2
JOURNAL ARTICLE
Adriana Shan, Mar Santos-Sebastián, Jesús Saavedra-Lozano
No abstract text is available yet for this article.
July 8, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38986525/respiratory-syncytial-virus-hospital-admission-rates-and-patients-characteristics-before-the-age-of-2-years-in-england-2015-2019
#3
JOURNAL ARTICLE
Maria João Fonseca, Saskia Hagenaars, Mathieu Bangert, Clare Flach, Richard D A Hudson
BACKGROUND: A granular understanding of respiratory syncytial virus (RSV) burden in England is needed to prepare for new RSV prevention strategies. We estimated the rates of RSV hospital admissions before the age of 2 years in England and described baseline characteristics. METHODS: A birth cohort of all infants born between March 1, 2015, and February 28, 2017 (n = 449,591) was established using Clinical Practice Research Datalink-Hospital Episode Statistics. Case cohorts included infants with admission for (1) RSV, (2) bronchiolitis, (3) any respiratory tract infection (RTI) <24 months and (4) RSV predicted by an algorithm <12 months...
July 5, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38986009/acute-focal-bacterial-nephritis-without-pyuria-a-peculiar-subtype-of-urinary-tract-infection
#4
JOURNAL ARTICLE
Juan Tu, Tiantian Lin, Huarong Li, Chaoying Chen
Acute focal bacterial nephritis (AFBN) without pyuria is a subtype of urinary tract infection in children, often leading to diagnostic challenges. The clinical characteristics of 6 children diagnosed with AFBN, who exhibited an absence of pyuria, were retrospectively summarized and compared with the control group consisting of 49 hospitalized AFBN children with pyuria. The cases of AFBN without pyuria presented with more severe inflammatory responses and were predisposed to complications, such as sepsis and neurological abnormalities...
July 5, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38986006/the-role-of-breastfeeding-in-acute-respiratory-infections-in-infancy
#5
JOURNAL ARTICLE
Emilia Vassilopoulou, Carlo Agostoni, Gavriela Feketea, Ilaria Alberti, Maria Lorella Gianni, Gregorio Paolo Milani
BACKGROUND: Acute respiratory infections (ARIs) affect the respiratory tract, are often caused by viruses such as respiratory syncytial virus and rhinovirus, and present symptoms such as coughing, fever, respiratory distress and breathing difficulty. The global adherence to exclusive breastfeeding (BF) for the first 6 months of life has reached 44%, supported by World Health Organization and United Nations International Children's Emergency Fund efforts. BF provides vital nutrients and contributes to infant immune system development, protecting against infections...
July 5, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38986004/emerging-and-re-emerging-enterovirus-infections-the-known-unknowns
#6
JOURNAL ARTICLE
Simon Cottrell, Catherine Moore
No abstract text is available yet for this article.
July 5, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38986001/predictors-of-neurological-disability-at-hospital-discharge-for-acyclovir-treated-pediatric-herpes-simplex-virus-encephalitis
#7
JOURNAL ARTICLE
Xuan Ngoc Tran, Son Thai Pham, Tung Huu Trinh, Jason J Liu
BACKGROUND: Herpes simplex virus encephalitis (HSE) is a rare but serious neurological infection that causes neurological dysfunction. Research is lacking on the clinical predictors of neurological outcomes and the optimal duration of therapy for pediatric HSE patients. In this study of pediatric HSE patients, we identified factors predicting neurological disability at hospital discharge and examined associations of acyclovir therapy duration with neurological outcomes. METHODS: This was a retrospective cohort study on 37 children diagnosed with HSE confirmed by polymerase chain reaction at age 1 month to 16 years from 2015 to 2021 in Ho Chi Minh City's Children's Hospital No...
July 3, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38986000/significance-of-procalcitonin-in-hospitalized-children-with-respiratory-syncytial-virus
#8
JOURNAL ARTICLE
James E Fisher, Shareef Shaheen, Eric Yau, Patrick Gavigan
No abstract text is available yet for this article.
July 3, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38985998/differential-serum-phosphate-levels-in-pediatric-febrile-syndromes-and-their-clinical-significance
#9
JOURNAL ARTICLE
Yonatan Milman, Daniel Landau, Asaf Lebel, Yoel Levinsky, Nufar Marcus, Adi Chezana, Liat Ashkenazi-Hoffnung
BACKGROUND: The potential of hypophosphatemia (HP) to differentiate between febrile syndromes and its clinical significance in children without sepsis were not previously described. METHODS: Data were retrospectively collected of febrile children aged 3 months to 18 years, hospitalized at general pediatric wards during 2010-2019. Phosphate levels were compared between bacterial infection (BI), viral infection (VI), and Kawasaki disease (KD). Regression analyses were used to evaluate the relationship between HP and outcome...
July 3, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38985996/host-defense-susceptibility-and-invasive-streptococcal-infections
#10
JOURNAL ARTICLE
Fani Ladomenou, Chrysoula Kosmeri, Ekaterini Siomou
No abstract text is available yet for this article.
July 3, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38985994/relative-effectiveness-of-the-nvx-cov2373-vaccine-compared-with-the-bnt162b2-vaccine-in-adolescents
#11
JOURNAL ARTICLE
Eun Sol Lee, Young June Choe, Seung Ah Choe, Eun Sun Gwak, Donghyok Kwon
This retrospective matched cohort study evaluated the efficacy of 2 doses of NVX-CoV2373 compared with that of BNT162b2 vaccines in preventing severe acute respiratory syndrome coronavirus 2 infection in adolescents. We analyzed 13-week risk differences and ratios between these 2 vaccines. The study included 465 NVX-CoV2373 and 465 BNT162b2 recipients. Throughout the follow-up period, 4.1% of NVX-CoV2373 recipients and 2.8% of BNT162b2 recipients contracted the severe acute respiratory syndrome coronavirus 2 infection...
July 3, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38985999/pentavalent-rotavirus-vaccine-coverage-and-trends-in-rotavirus-detection-before-and-after-this-vaccination-in-chengdu-china
#12
JOURNAL ARTICLE
Guoguang Xiao, Tingting Zhu, Zhiling Wang, Xiaoping Xie, Min Shu, Shan Gao, Liyuan Wang, Wei Zhou, Jianjun Deng, Yongmei Xie, Fan Yu
Pentavalent rotavirus vaccine (RV5) coverage and changes in rotavirus detection in the prevaccine and postvaccine era in Chengdu were investigated. The results showed that the coverage of RV5 had been increasing but still relatively low. Nevertheless, the dramatical decline in the rotavirus detection was observed after the introduction of RV5. Efforts to improve the coverage of rotavirus vaccination should continue to maximize the public health benefits.
July 2, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38985997/blood-cultures-in-children-maximizing-their-usefulness
#13
JOURNAL ARTICLE
Thao T Truong, Jacky Lu, Jennifer Dien Bard
No abstract text is available yet for this article.
July 2, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38985986/population-attributable-risk-of-wheeze-in-2-6-year-old-children-following-a-respiratory-syncytial-virus-lower-respiratory-tract-infection-in-the-first-2-years-of-life
#14
JOURNAL ARTICLE
Shabir A Madhi, Ana Ceballos, Luis Cousin, Joseph B Domachowske, Joanne M Langley, Emily Lu, Thanyawee Puthanakit, Mika Rämet, Amy Tan, Khalequ Zaman, Bruno Anspach, Agustin Bueso, Elisa Cinconze, Jo Ann Colas, Ulises D'Andrea, Ilse Dieussaert, Janet A Englund, Sanjay Gandhi, Lisa Jose, Hanna Karhusaari, Joon Hyung Kim, Nicola P Klein, Outi Laajalahti, Runa Mithani, Martin O C Ota, Mauricio Pinto, Peter Silas, Sonia K Stoszek, Auchara Tangsathapornpong, Jamaree Teeratakulpisarn, Miia Virta, Rachel A Cohen
BACKGROUND: There is limited evidence regarding the proportion of wheeze in young children attributable to respiratory syncytial virus lower respiratory tract infections (RSV-LRTI) occurring early in life. This cohort study prospectively determined the population attributable risk (PAR) and risk percent (PAR%) of wheeze in 2-<6-year-old children previously surveilled in a primary study for RSV-LRTI from birth to their second birthday (RSV-LRTI<2Y). METHODS: From 2013 to 2021, 2-year-old children from 8 countries were enrolled in this extension study (NCT01995175) and were followed through quarterly surveillance contacts until their sixth birthday for the occurrence of parent-reported wheeze, medically-attended wheeze or recurrent wheeze episodes (≥4 episodes/year)...
July 1, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38920389/rsv-in-young-children-during-and-after-the-covid-19-pandemic-implications-for-delaying-the-age-of-first-infection
#15
JOURNAL ARTICLE
Zoe Hancock, Peter Muir, Paul North, Philip Williams, Nicholas Veasey, Adam Finn, Robin Marlow
Nonpharmaceutical interventions introduced in the United Kingdom's response to the COVID-19 pandemic disrupted the transmission of other childhood infections. We report changes in seasonality, age dynamics and severity of respiratory syncytial virus infections between 2019 and 2023. These data show the potential effects of delaying respiratory syncytial virus exposure and may provide insights for the implementation of treatments preventing infection during early infancy.
June 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38920385/acyclovir-dosing-practices-across-a-multicenter-cohort-of-neonatal-intensive-care-units
#16
JOURNAL ARTICLE
Henry P Foote, Haley Thomassy, Leonardo Baquero, Mina Cayli, Elijah Jacobs, Anish Paladugu, Anisha Roy, Elizabeth Heyward, Reese H Clark, Christoph P Hornik, Daniel K Benjamin, Daniel K Benjamin, Rachel G Greenberg
BACKGROUND: Acyclovir is the first-line therapy for neonatal herpes simplex virus infections. Therapy can mitigate morbidity and mortality but carries a risk for toxicity. We aimed to compare acyclovir dosing in neonatal intensive care units to published recommendations based on population pharmacokinetic (PopPK) analysis. METHODS: We performed a multicenter cohort study of infants in neonatal intensive care units managed by the Pediatrix Medical Group from 1997 to 2020...
June 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38920379/increased-severity-of-mycoplasma-pneumoniae-infections-in-spanish-children
#17
JOURNAL ARTICLE
Ana Méndez-Echevarría, Laura Calle-Miguel, Sheila Miralbés, Sagrario Barreiro-Pérez, Olga Afonso-Rodriguez, José Antonio Soler-Simón, Ana Espeleta, Ana Belén Jiménez-Jiménez, Alejandra Méndez-Sánchez, Joseba Iñaki Rementeria-Radigales, Fuensanta Guerrero-Del-Cueto, Vanessa Laveglia, Irene Ortiz-Valentín, Emilio Gómez-Mera, Verónica Fernández-Puentes, Lucía Rodríguez-Noriega-Bejar, Matilde Bustillo, Azucena Retuerta, José Fernàndez-Cantalejo, Laura Sanz-Rueda, María Mercedes Ibáñez, Arantxa Berzosa, Berta Fernández-Ledesma, Alicia Álvaro, Teresa Santamaría-Barrena, Beatriz Carazo-Gallego, Cinta Moraleda, Cristina Calvo
BACKGROUND: Since the end of 2023, an elevated incidence and severity of Mycoplasma pneumoniae infections among children in Asia has been noted. Subsequently, this trend was observed in several European countries although limited data are currently available. We conducted a national study to delineate the ongoing M. pneumoniae outbreak in our country. METHODS: A multicenter retrospective observational study was conducted across 32 hospitals in Spain, encompassing patients under 18 years old hospitalized for M...
June 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38920375/evaluation-of-anti-glycopeptidolipid-core-immunoglobulin-a-antibody-detection-for-the-diagnosis-of-nontuberculous-mycobacterial-cervicofacial-lymphadenitis
#18
JOURNAL ARTICLE
Samuel H Willemse, Marjolijn A E M Oomens, Luc H E Karssemakers, Jerome A Lindeboom, Willem H Schreuder, Jean-Pierre T F Ho, Martijn van der Kuip, Killian E Vlaming, Tanja M Kaptein, Jan de Lange
A multicenter cross-sectional diagnostic study was carried out including 45 children with nontuberculous mycobacterial cervicofacial lymphadenitis and controls. The tested immunoassay, detecting M. avium-specific anti-glycopeptidolipid-core immunoglobulin A antibodies, had inadequate diagnostic performance in the studied population and seems to be of no additional value in detecting cases of nontuberculous mycobacterial cervicofacial lymphadenitis.
June 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38917027/antifungal-drug-usage-in-european-neonatal-units-a-multicenter-weekly-point-prevalence-study
#19
JOURNAL ARTICLE
Elisavet Chorafa, Elias Iosifidis, Andrea Oletto, Adilia Warris, Elio Castagnola, Roger Bruggemann, Andreas H Groll, Thomas Lehrnbecher, Laura Ferreras Antolin, Alessio Mesini, Eleni Agakidou, Tiziana Controzzi, Maia De Luca, Gabriel Dimitriou, Marieke Emonts, Susanna Esposito, Aurora Fernàndez-Polo, Elisabetta Ghimenton-Walters, Despoina Gkentzi, Carlos Grasa, Eleftheria Hatzidaki, Piia Jõgi, Kornelija Kildonaviciute, Angeliki Kontou, Alessa Leibold-Aguinarte, Angela Manzanares, Natalia Mendoza-Palomar, Tuuli Metsvaht, Maria Noni, Stéphane Paulus, Serafina Perrone, Elena Rincón-López, Lorenza Romani, Laura Sánchez, Benhur Sirvan Cetin, Vana Spoulou, Volker Strenger, Eleni Vergadi, Serena Villaverde, Marco Vuerich, Elena Zamora-Flores, Emmanuel Roilides
BACKGROUND: Data on antifungal prescribing in neonatal patients are limited to either single-center or single-country studies or to 1-day recording. Therefore, we assessed antifungal longitudinal usage in neonatal units (NUs) within Europe. METHODS: CALYPSO, a prospective weekly point prevalence study on antifungal drug usage in NUs in 18 hospitals (8 European countries), was conducted in 2020 during a 12-week period. All patients receiving systemic antifungals were included...
June 25, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38917026/projected-public-health-impact-of-a-universal-rotavirus-vaccination-program-in-france
#20
JOURNAL ARTICLE
Sharomi Oluwaseun, Lauren Cagnan, Ilaria Xausa, Robert B Nachbar, Laurie Levy Bachelot, Yao-Hsuan Chen, Cristina Carias
OBJECTIVE: In June 2022, French health authorities issued a universal recommendation for routine administration and reimbursement of rotavirus vaccines in infants. Given this recent recommendation by French health authorities, we sought to understand the public health impact of a universal rotavirus vaccination strategy compared with no vaccination. MATERIALS AND METHODS: A deterministic, age-structured, nonlinear dynamic transmission model, accounting for herd immunity, was developed...
June 25, 2024: Pediatric Infectious Disease Journal
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