journal
https://read.qxmd.com/read/38610113/pediatric-penicillin-allergy-labels-influence-of-race-insurance-and-area-deprivation-index
#1
LETTER
Zoya Siddiqui, Brian R Lee, Amanda Nedved, Jennifer McKinsey, Frances Turcotte Benedict, Brandi Missel, Aarti Pandya, Rana E El Feghaly
No abstract text is available yet for this article.
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38581158/global-assessment-of-the-knowledge-and-confidence-in-managing-allergic-disorders-among-primary-care-pediatricians-across-europe-an-eaaci-task-force-report
#2
JOURNAL ARTICLE
M Cabrera, D Ryan, M Erlewyn-Lajeunesse, M Levin, A Martínez-Cañavate, C Villaizán Pérez, E Angier, J Trujillo, J M Cárdenas-Rebollo, L Reali
BACKGROUND: Pediatricians are often the first point of contact for children in Primary Care (PC), but still perceive gaps in their allergy knowledge. We investigated self-perceived knowledge gaps and educational needs in pediatricians across healthcare systems in Europe so that future educational initiatives may better support the delivery of allergy services in PC. METHOD: A multinational survey was circulated to pediatricians who care for children and adolescents with allergy problems in PC by the EAACI Allergy Educational Needs in Primary Care Pediatricians Task Force from February to March 2023...
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38581140/autism-in-patients-with-eosinophilic-gastrointestinal-disease-a-systematic-review-with-meta-analysis
#3
REVIEW
Rian Vilar Lima, Maria Carolina Rocha Muniz, Luana Lima Barroso, Maria Clara Apolônio Pinheiro, Yuri Marques Teixeira Matos, Sarah Baltasar Ribeiro Nogueira, Hildenia Baltasar Ribeiro Nogueira
PURPOSE: Neurodevelopmental disorders, such as autism spectrum disorder (ASD), have been increasingly associated with eosinophilic gastrointestinal disorders (EGID). However, the relationship between these diseases remains unclear. We performed a systematic review with meta-analysis to address this issue. METHODS: The search was performed according to the PRISMA guidelines using descriptors for ASD and EGIDs from the MEDLINE, Embase, PsycInfo, LILACS, and Web of Science databases...
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38573103/reply-to-wang-et%C3%A2-al
#4
LETTER
Shay Nemet, Ruslan Sergienko, Oded Shamriz
No abstract text is available yet for this article.
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38572778/a-14-step-desensitization-protocol-for-sebelipase-alfa-hypersensitivity-in-a-patient-with-wolman-disease-and-secondary-hemophagocytic-lymphohistiocytosis
#5
JOURNAL ARTICLE
Minh H N Nguyen, Rachel Bruening, Trent Abel, Shannon Lyons, Brenna Denhardt, Jenna Moore, Panida Sriaroon, Monica Hajirawala, Alexander Y Kim
No abstract text is available yet for this article.
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38566436/feeding-difficulties-in-children-with-food-allergies-an-eaaci-task-force-report
#6
REVIEW
Sarah-Anne Hill, Ulugbek Nurmatov, Audrey DunnGalvin, Imke Reese, Mario C Vieira, Natalie Rommel, Christophe Dupont, Carina Venter, Antonella Cianferoni, Joanne Walsh, Glauce Yonamine, Alexia Beauregard, Rosan Meyer, Marta Vazquez-Ortiz
The term "feeding difficulties" refers to a spectrum of phenotypes characterized by suboptimal intake of food and/or lack of age-appropriate eating habits. While it is evident that feeding difficulties are prevalent within healthy children, no consensus has been reached for those with food allergies. The aim of this study was to systematically review all the available literature reporting the prevalence of feeding difficulties within food allergic children. We searched eight international electronic databases for all published studies until June 2022...
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38566365/design-of-the-intervention-to-reduce-early-peanut-allergy-in-children-ireach-a-practice-based-clinical-trial
#7
RANDOMIZED CONTROLLED TRIAL
Lucy A Bilaver, Adolfo J Ariza, Helen J Binns, Jialing Jiang, Rich Cohn, Samantha Sansweet, Haley Hultquist, Joy Laurienzo Panza, Alkis Togias, Ruchi S Gupta
BACKGROUND: Introducing peanut products early can prevent peanut allergy (PA). The "Addendum guidelines for the prevention of PA in the United States" (PPA guidelines) recommend early introduction of peanut products to low and moderate risk infants and evaluation prior to starting peanut products for infants at high risk for PA (those with severe eczema and/or egg allergy). Rapid adoption of guidelines could aid in lowering the prevalence of PA. The Intervention to Reduce Early (Peanut) Allergy in Children (iREACH) trial was designed to promote PPA guideline adherence by pediatric clinicians...
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38556806/clarifying-the-use-of-hierarchical-clustering-in-analyzing-allergen-molecule-sensitization-profiles
#8
LETTER
Sevda Tuten Dal, Bulent Enis Sekerel
No abstract text is available yet for this article.
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38556800/is-asthma-in-children-still-increasing-20-year-prevalence-trends-in-northern-sweden
#9
JOURNAL ARTICLE
Linnea Hedman, Martin Andersson, Anders Bjerg, Helena Backman, Maja Af Klinteberg, Anna Winberg, Eva Rönmark
BACKGROUND: In the present study, we describe prevalence trends of asthma and investigate the association with asthma symptoms, use of asthma medication, and asthma severity among 8-year-old children in Norrbotten, Sweden in 1996, 2006, and 2017. METHODS: Within the Obstructive Lung Disease in Northern Sweden (OLIN) studies, three pediatric cohorts were recruited in 1996, 2006, and 2017 respectively. Identical methods were used; all children in first and second grade (median age 8 years) in three municipalities were invited to a parental questionnaire survey, completed by n = 3430 in 1996 (97% participation), n = 2585 in 2006 (96%), and n = 2785 in 2017 (91%)...
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38556795/editorial-comment-on-epigenomic-and-epigenetic-investigations-of-food-allergy
#10
EDITORIAL
Cristina Serio, Agnes S Y Leung, Philippe Eigenmann, Guillaume Lezmi
No abstract text is available yet for this article.
April 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38529692/prenatal-and-postnatal-exposure-to-antibiotics-and-risk-of-food-allergy-in-the-offspring-a-nationwide-birth-cohort-study-in-south-korea
#11
JOURNAL ARTICLE
Jiyeon Oh, Myeongcheol Lee, Jaeyu Park, Hyeon Jin Kim, Seung Won Lee, Masoud Rahmati, Ai Koyanagi, Lee Smith, Min Seo Kim, Guillermo F López Sánchez, Elena Dragioti, Chanyang Min, Nikolaos G Papadopoulos, Youn Ho Shin, Jae Il Shin, Dong Keon Yon
BACKGROUND: There are only preliminary studies examining the associations of postnatal antibiotic exposure with food allergy in childhood, and the effect of antibiotic exposure in utero has not been resolved. Thus, we aimed to investigate the effect of prenatal and postnatal antibiotic exposure on the risk of food allergy in childhood. METHODS: Using the nationwide birth cohort in South Korea, all 3,163,206 infants (pairing mother; n = 2,322,735) born in South Korea between 2010 and 2017 were included in the analysis...
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38528707/psychological-support-needs-for-children-with-food-allergy-and-their-families-a-systematic-review
#12
REVIEW
Rebecca C Knibb, Christina J Jones, Linda J Herbert, Cassandra Screti
This systematic review aimed to review the evidence for psychological support for children with food allergies and their families, identify effective psychological interventions, and highlight the support needs for this group. A systematic search was undertaken across six databases (up to October 2023). Articles were checked by three reviewers for inclusion. Study data were extracted, and quality was assessed using the Mixed Methods Appraisal Tool. A narrative synthesis was undertaken. A total of 11 papers were included (n = 838 participants)...
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38520061/transcriptomic-changes-associated-with-oral-immunotherapy-for-food-allergy
#13
REVIEW
Sarah E Ashley, Anthony Bosco, Mimi L K Tang
This review summarizes recent advances in characterizing the transcriptional pathways associated with outcomes following Oral Immunotherapy. Recent technological advances including single-cell sequencing are transforming the ways in which the transcriptional landscape is understood. The application of these technologies is still in its infancy in food allergy but here we summarize current understanding of gene expression changes following oral immunotherapy for food allergy and specific signatures underpinning the different clinical outcomes of desensitization and remission (sustained unresponsiveness)...
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38520021/cobraped-cohort-do-sensitization-patterns-differentiate-children-with-severe-asthma-from-those-with-a-milder-disease
#14
JOURNAL ARTICLE
Stéphanie Lejeune, Naïm Bouazza, Pascale Roland Nicaise, Valérie Jolaine, Léa Roditis, Christophe Marguet, Flore Amat, Patrick Berger, Michael Fayon, Jean-Christophe Dubus, Sophie Valois, Philippe Reix, Mathieu Pellan, Jacques Brouard, Raphael Chiron, Lisa Giovannini-Chami, Jacques de Blic, Antoine Deschildre, Guillaume Lezmi
BACKGROUND: It is unclear whether sensitization patterns differentiate children with severe recurrent wheeze (SRW)/severe asthma (SA) from those with non-severe recurrent wheeze (NSRW)/non-severe asthma (NSA). Our objective was to determine whether sensitization patterns can discriminate between children from the French COBRAPed cohort with NSRW/NSA and those with SRW/SA. METHODS: IgE to 112 components (c-sIgE) (ImmunoCAP® ISAC) were analyzed in 125 preschools (3-6 years) and 170 school-age children (7-12 years)...
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38519873/editorial-comment-on-the-special-issue-omics-in-food-allergy
#15
EDITORIAL
Riccardo Castagnoli, Ivan Taietti, Agnes Sze-Yin Leung, Philippe Eigenmann
No abstract text is available yet for this article.
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38512103/il-17-gal-10-and-tgf-%C3%AE-are-promising-noninvasive-biomarkers-of-pediatric-eosinophilic-esophagitis
#16
JOURNAL ARTICLE
Martina Votto, Matteo Naso, Mara De Amici, Riccardo Castagnoli, Annalisa De Silvestri, Maria De Filippo, Giorgia Testa, Gian Luigi Marseglia, Amelia Licari
No abstract text is available yet for this article.
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38491810/comment-on-nemet-et%C3%A2-al
#17
LETTER
Chen Wang, Jian-Te Lee
No abstract text is available yet for this article.
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38491795/benralizumab-in-children-with-severe-eosinophilic-asthma-pharmacokinetics-and-long-term-safety-tate-study
#18
JOURNAL ARTICLE
H James Wedner, Takao Fujisawa, Theresa W Guilbert, Masanori Ikeda, Vinay Mehta, Jonathan S Tam, Pradeep B Lukka, Sara Asimus, Tomasz Durżyński, James Johnston, Wendy I White, Mihir Shah, Viktoria Werkström, Maria L Jison
BACKGROUND: Benralizumab is an anti-interleukin-5 receptor α monoclonal antibody approved as an add-on maintenance treatment for patients with uncontrolled severe asthma. Prior Phase 3 studies have evaluated benralizumab in patients aged ≥12 years with severe uncontrolled asthma. The TATE study evaluated the pharmacokinetics (PK), pharmacodynamics (PD), and safety of benralizumab treatment in children. METHODS: TATE was an open-label, Phase 3 study of benralizumab in children aged 6-11 years from the United States and Japan (plus participants aged 12-14 years from Japan) with severe eosinophilic asthma...
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38488437/management-of-food-protein-induced-allergic-proctocolitis-in-italy-a-nationwide-survey-by-sigenp
#19
JOURNAL ARTICLE
Maurizio Mennini, Elena Lionetti, Monica Malamisura, Giovanni Di Nardo, Renata Auricchio, Paolo Lionetti, Claudio Romano
No abstract text is available yet for this article.
March 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38483116/role-of-skin-management-in-the-prevention-of-atopic-dermatitis-and-food-allergy
#20
REVIEW
Elizabeth Huiwen Tham, Kiwako Yamamoto-Hanada, Agnes Sze Yin Leung, Yukihiro Ohya
Food allergy is postulated to originate from cutaneous sensitization through a disrupted skin barrier, particularly in atopic dermatitis (AD). Strategies for food allergy prevention currently centre around early allergic food introduction, but there is now increasing evidence for the role of early skin barrier restoration in the form of prophylactic emollient therapy and early aggressive, proactive treatment of established AD for food allergy prevention. Research gaps that remain to be addressed include the type of emollient or anti-inflammatory medication, which confers the greatest efficacy in preventive or proactive skin treatment, respectively, the duration of therapy, and the window of opportunity for these interventions...
March 2024: Pediatric Allergy and Immunology
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