Srivatsa Surya Vasudevan, Arun Subash, Fena Mehta, Tiba Yamin Kandrikar, Rupak Desai, Kaif Khan, Sneha Khanduja, Aakanksha Pitliya, Lekhya Raavi, Sai Gautham Kanagala, Piyush Gondaliya
The mortality rate of Nipah virus (NiV) can vary in different regions, and its pattern across timelines has yet to be assessed. The primary objective is to perform a comparative analysis of mortality rates across different timelines and countries. Articles reporting NiV mortality from inception to November 2023 were analyzed in PubMed, Ovid Embase, Scopus, and Web of Science databases. A meta-analysis utilizing random-effects models determined the mortality rate secondary to NiV complications. The initial search strategy yielded 1213 records, of which 36 articles met the inclusion criteria, comprising 2736 NiV patients...
July 20, 2024: Pathogens and Global Health
Syahrul Amin Sa'adon, Nur Hana Jasni, Hairul Hisham Hamzah, Nurulhasanah Othman
The development of rapid, accurate, and efficient detection methods for protozoan parasites can substantially control the outbreak of protozoan parasites infection, which poses a threat to global public health. Idealistically, electrochemical biosensors would be able to overcome the limitations of current detection methods due to their simplified detection procedure, on-site quantitative analysis, rapid detection time, high sensitivity, and portability. The objective of this scoping review is to evaluate the current state of electrochemical biosensors for detecting protozoan parasites...
July 20, 2024: Pathogens and Global Health
Alisa Aliaga-Samanez, David Romero, Kris Murray, Marina Segura, Raimundo Real, Jesús Olivero
Climate change may increase the risk of dengue and yellow fever transmission by urban and sylvatic mosquito vectors. Previous research primarily focused on Aedes aegypti and Aedes albopictus . However, dengue and yellow fever have a complex transmission cycle involving sylvatic vectors. Our aim was to analyze how the distribution of areas favorable to both urban and sylvatic vectors could be modified as a consequence of climate change. We projected, to future scenarios, baseline distribution models already published for these vectors based on the favorability function, and mapped the areas where mosquitoes' favorability could increase, decrease or remain stable in the near (2041-2060) and distant (2061-2080) future...
July 7, 2024: Pathogens and Global Health
Saulo Nascimento de Melo, David Soeiro Barbosa, Daniel Cardoso Portela Câmara, Taynãna César Simões, Lia Puppim Buzanovsky, Anna Gabryela Sousa Duarte, Ana Nilce Silveira Maia-Elkhoury, Diogo Tavares Cardoso, Lucas Edel Donato, Guilherme Loureiro Werneck, Fábio Raphael Pascoti Bruhn, Vinícius Silva Belo
Understanding the distribution of tegumentary leishmaniasis (TL) in different periods enables the adequate conduction of actions at the public health level. The present study analyzes the spatiotemporal evolution of TL incidence rates in the municipalities of Brazil and identifies priority areas from 2001 to 2020. Notifications of new cases were analyzed employing space-time scan statistics and Local Indicators of Spatial Association. As TL incidence rates presented a downward trend in most Brazilian municipalities, spatiotemporal clusters of high relative risks (RR) were more frequent in the first decade of the series...
June 21, 2024: Pathogens and Global Health
Reza Eshraghi, Ashkan Bahrami, Motahare Karimi Houyeh, Maryam Nasr Azadani
In the fourth year of the COVID-19 occurrence, a new COVID-19 variant, JN.1, has emerged and spread globally and become the dominant strain in several regions. It has some specific mutations in its spike proteins, empowering it with higher transmissibility. Regarding the significance of the issue, understanding the clinical and immunological traits of JN.1 is critical for enhancing health strategies and vaccination efforts globally, with the ultimate goal of bolstering our collective response to the pandemic...
June 17, 2024: Pathogens and Global Health
Zeeshan Mustafa, Haris Manzoor Khan, Syed Ghazanfar Ali, Hiba Sami, Ahmad Almatroudi, Masood Alam Khan, Arif Khan, Wafa Abdullah I Al-Megrin, Khaled S Allemailem, Islam Ahmad, Asmaa El-Kady, Mohammed Suliman Al-Muzaini, Mohammad Azam Khan, Mohd Azam
Dengue fever poses a significant global health threat, with symptoms including dengue hemorrhagic fever and dengue shock syndrome. Each year, India experiences fatal dengue outbreaks with severe manifestations. The primary cause of severe inflammatory responses in dengue is a cytokine storm. Individuals with a secondary dengue infection of a different serotype face an increased risk of complications due to antibody-dependent enhancement. Therefore, it is crucial to identify potential risk factors and biomarkers for effective disease management...
June 17, 2024: Pathogens and Global Health
Maria Angelica Carrillo, Alisa Maria Gessler, Tatiana Rivera Ramirez, Rocío Cárdenas Sanchez, Jörg Lindenmeier, Winfried V Kern, Axel Kroeger
Arboviral diseases remain a significant health concern worldwide, with over half the world's population at risk for dengue alone. Without a vaccine or targeted treatment, the most effective strategy of prevention is vector management with community involvement. mHealth interventions, like WhatsApp, offer promising results for engaging communities and promoting healthier behaviors. This study explores the feasibility of integrating WhatsApp in vector control activities to improve arbovirus prevention in Colombia...
May 24, 2024: Pathogens and Global Health
Mariano Martini, Niccolò Riccardi, Omar Simonetti, Davide Orsini, Francesco Samassa, Alessandra Parodi
Trachoma is one of the oldest known causes of blindness in humans and it is caused by the intracellular Gram-negative bacterium Chlamydia trachomatis serovars A, B, Ba and C. Its transmission has historically been related to poorness, overcrowded housing and scarce hygiene. We have traced the history of trachoma in Italy in the 19th and 20th centuries, among people living in Italy, those who immigrated to America and the population in the colonies, with a focus on Libya (1912-1943). Trachoma knowledge and perception in Italy and in its colonies was ambiguous during the 19th and 20th centuries...
April 21, 2024: Pathogens and Global Health
Fabio Scarpa, Massimo Ciccozzi
No abstract text is available yet for this article.
April 14, 2024: Pathogens and Global Health
Laxit K Bhatt, Jitendra H Patel, Chitrang R Shah, Sudhir R Patel, Shital D Patel, Vipul A Patel, Rajesh Sundar, Mukul R Jain
Occupational immunization is an integral part of institutional occupational safety and health (OSH) programs. Laboratory animal workers (LAWs) are personnel working with various small and large vertebrate animals. LAWs are at the risk of contracting a myriad of zoonotic infections as they are occupationally exposed to animals and their biological products. Immunizing employees against such zoonotic pathogens is the best way to prevent disease transmission. This review provides information on various zoonotic diseases, vaccines available to protect against such infections, and vaccination schedules...
March 20, 2024: Pathogens and Global Health
Giovanni Rezza
Several outbreaks of chikungunya and dengue occurred on Mediterranean coasts during the hot season in the last two decades. Aedes albopictus was the vector involved in all the events. As a consequence of climate change, the 'Tiger' mosquito is now spreading through central Europe, and in the summer of 2023, for the first time, mosquito control measures were implemented in Paris to prevent autochthonous transmission of dengue. Rapid changes in the distribution of tropical disease vectors need to be taken into account in future risk assessment activities...
February 29, 2024: Pathogens and Global Health
Babatunde Adewale, Margaret A Mafe, Hammed O Mogaji, Joshua B Balogun, Medinat A Sulyman, Morakinyo B Ajayi, David O Akande, Emmanuel O Balogun
Schistosomiasis and anemia, are one of the leading global public health problem among children between age 5 and 14 years in marginalized settings. In this study, we provide prevalence and intensity data for both conditions in three southwestern states of Nigeria, where such are lacking. Epidemiological assessment involving parasitological analysis of urine and blood samples was conducted among 1783 consenting school-aged children in Ondo, Osun, Ekiti States of Nigeria. Participants' age and sex data were obtained using field forms, and statistical analysis was performed in R software with a significance level of 95%...
February 28, 2024: Pathogens and Global Health
Francesco Branda, Marta Giovanetti, Fabio Scarpa, Massimo Ciccozzi
No abstract text is available yet for this article.
February 27, 2024: Pathogens and Global Health
Sandro Provenzano, Omar Enzo Santangelo, Vincenza Gianfredi
BACKGROUND: Contagious exanthematous diseases are becoming a major public health problem. The purpose of this study was to evaluate the potential epidemiological trend of four infectious exanthematous diseases in Italy through the searches on the internet. METHODS: We used the following Italian search term: 'Sesta malattia' (Sixth Disease, in English), 'Eritema Infettivo' (also knows 'Quinta malattia' in Italian; Fifth Disease in English), 'Quarta malattia' (Fourth Disease in English) and 'Scarlattina' (Scarlet fever in English)...
February 27, 2024: Pathogens and Global Health
Sylvia K Ofori, Jessica S Schwind, Kelly L Sullivan, Gerardo Chowell, Benjamin J Cowling, Isaac Chun-Hai Fung
Seroprevalence studies assessing community exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Ghana concluded that population-level immunity remained low as of February 2021. Thus, it is important to demonstrate how increasing vaccine coverage reduces the economic and public health impacts associated with SARS-CoV-2 transmission. To that end, this study used a Susceptible-Exposed-Presymptomatic-Symptomatic-Asymptomatic-Recovered-Dead-Vaccinated compartmental model to simulate coronavirus disease 2019 (COVID-19) transmission and the role of public health interventions in Ghana...
February 6, 2024: Pathogens and Global Health
Faith T T Hungwe, Katherine M Laycock, Tlhalefo D Ntereke, Rorisang Mabaka, Giacomo M Paganotti
Arboviruses are an existing and expanding threat globally, with the potential for causing devastating health and socioeconomic impacts. Mitigating this threat necessitates a One Health approach that integrates vector surveillance, rapid disease detection, and innovative prevention and control measures. In Southern Africa, limited data on the epidemiology of arboviruses, their vectors, and their hosts prevent an effective response. We reviewed the current knowledge on arboviruses in Southern Africa and identified opportunities for further research...
December 11, 2023: Pathogens and Global Health
Shahira Abdelaziz Ali Ahmed, Annalisa Quattrocchi, Panagiotis Karanis
(1) Background: Organ transplant recipients (OTRs) are vulnerable groups at risk of parasitic infections. This systematic review and meta-analysis aimed to evaluate the overall prevalence of Cryptosporidium sp. in OTRs and shed light on this potentially serious complication of organ transplantation. (2) Methods: We systematically searched studies on Cryptosporidium sp. infections in OTRs in four databases (Academia, PubMed, Scopus, and Science Direct). Random effects models were used to calculate pooled prevalence estimates with 95% confidence intervals (CIs)...
December 6, 2023: Pathogens and Global Health
Raghad H F Bashabsheh, O'la Al-Fawares, Iyad Natsheh, Roba Bdeir, Rozan O Al-Khreshieh, Hasan H F Bashabsheh
Staphylococcus aureus is a Gram-positive bacterium and one of the most prevalent infectious disease-related causes of morbidity and mortality in adults. This pathogen can trigger a broad spectrum of diseases, from sepsis and pneumonia to severe skin infections that can be fatal. In this review, we will provide an overview of S. aureus and discuss the extensive literature on epidemiology, transmission, genetic diversity, evolution and antibiotic resistance strains, particularly methicillin resistant S. aureus (MRSA)...
November 25, 2023: Pathogens and Global Health
Vishnu Teja Nallapati, Nitin Gupta, Manjunath H Hande, Kavitha Saravu
INTRODUCTION: Chloroquine (CQ) is the drug of choice for treating uncomplicated Plasmodium vivax (P. vivax) malaria in India. The knowledge about the exact burden of CQ resistance in P. vivax in India is scarce. Therefore, this systematic review aimed to assess the prevalence of CQ resistance in reported P. vivax cases from India. METHODS: PubMed, EMBASE, and Web of Science, were searched using the search string: 'Malaria AND vivax AND chloroquine AND (resistance OR resistant) AND India'...
November 23, 2023: Pathogens and Global Health
Sangeeta Dey, Yadlapalli S Kusuma, Shashi Kant, Dewesh Kumar, Retheesh Babu Gopalan, Parikipandla Sridevi, Sumit Aggarwal
Vaccination against COVID-19 is vital for achieving herd immunity, and the Government of India has adopted several strategies to achieve coverage. Vaccine hesitancy was identified as a potential obstacle in combating COVID-19. This study aimed to review the COVID-19 vaccine acceptance and hesitancy, and factors associated with vaccine hesitancy based on studies conducted in Indian populations. The data sources (PubMed, Scopus, and Google Scholar) were searched by following PRISMA guidelines, and the search was done in September 2022...
November 20, 2023: Pathogens and Global Health
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