journal
https://read.qxmd.com/read/37224238/what-i-learned-in-school-today
#1
JOURNAL ARTICLE
Mira G Taichman
No abstract text is available yet for this article.
May 24, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37224235/ketamine-and-ect-in-depression-risks-and-rewards
#2
EDITORIAL
Robert Freedman
No abstract text is available yet for this article.
May 24, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37224233/empowered-or-traumatized-a-call-for-evidence-informed-armed-assailant-drills-in-u-s-schools
#3
JOURNAL ARTICLE
Mary Beth Miotto, Robin Cogan
No abstract text is available yet for this article.
May 24, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37224232/ketamine-versus-ect-for-nonpsychotic-treatment-resistant-major-depression
#4
JOURNAL ARTICLE
Amit Anand, Sanjay J Mathew, Gerard Sanacora, James W Murrough, Fernando S Goes, Murat Altinay, Amy S Aloysi, Ali A Asghar-Ali, Brian S Barnett, Lee C Chang, Katherine A Collins, Sara Costi, Sidra Iqbal, Manish K Jha, Kamini Krishnan, Donald A Malone, Sina Nikayin, Steven E Nissen, Robert B Ostroff, Irving M Reti, Samuel T Wilkinson, Kathy Wolski, Bo Hu
BACKGROUND: Electroconvulsive therapy (ECT) and subanesthetic intravenous ketamine are both currently used for treatment-resistant major depression, but the comparative effectiveness of the two treatments remains uncertain. METHODS: We conducted an open-label, randomized, noninferiority trial involving patients referred to ECT clinics for treatment-resistant major depression. Patients with treatment-resistant major depression without psychosis were recruited and assigned in a 1:1 ratio to receive ketamine or ECT...
May 24, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37222476/early-versus-later-anticoagulation-for-stroke-with-atrial-fibrillation
#5
JOURNAL ARTICLE
Urs Fischer, Masatoshi Koga, Daniel Strbian, Mattia Branca, Stefanie Abend, Sven Trelle, Maurizio Paciaroni, Götz Thomalla, Patrik Michel, Krassen Nedeltchev, Leo H Bonati, George Ntaios, Thomas Gattringer, Else-Charlotte Sandset, Peter Kelly, Robin Lemmens, P N Sylaja, Diana Aguiar de Sousa, Natan M Bornstein, Zuzana Gdovinova, Takeshi Yoshimoto, Marjaana Tiainen, Helen Thomas, Manju Krishnan, Gek C Shim, Christoph Gumbinger, Jochen Vehoff, Liqun Zhang, Kosuke Matsuzono, Espen Kristoffersen, Philippe Desfontaines, Peter Vanacker, Angelika Alonso, Yusuke Yakushiji, Caterina Kulyk, Dimitri Hemelsoet, Sven Poli, Ana Paiva Nunes, Nicoletta Caracciolo, Peter Slade, Jelle Demeestere, Alexander Salerno, Markus Kneihsl, Timo Kahles, Daria Giudici, Kanta Tanaka, Silja Räty, Rea Hidalgo, David J Werring, Martina Göldlin, Marcel Arnold, Cecilia Ferrari, Seraina Beyeler, Christian Fung, Bruno J Weder, Turgut Tatlisumak, Sabine Fenzl, Beata Rezny-Kasprzak, Arsany Hakim, Georgia Salanti, Claudio Bassetti, Jan Gralla, David J Seiffge, Thomas Horvath, Jesse Dawson
BACKGROUND: The effect of early as compared with later initiation of direct oral anticoagulants (DOACs) in persons with atrial fibrillation who have had an acute ischemic stroke is unclear. METHODS: We performed an investigator-initiated, open-label trial at 103 sites in 15 countries. Participants were randomly assigned in a 1:1 ratio to early anticoagulation (within 48 hours after a minor or moderate stroke or on day 6 or 7 after a major stroke) or later anticoagulation (day 3 or 4 after a minor stroke, day 6 or 7 after a moderate stroke, or day 12, 13, or 14 after a major stroke)...
May 24, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37212442/a-dual-chamber-leadless-pacemaker
#6
JOURNAL ARTICLE
Reinoud E Knops, Vivek Y Reddy, James E Ip, Rahul Doshi, Derek V Exner, Pascal Defaye, Robert Canby, Maria Grazia Bongiorni, Morio Shoda, Gerhard Hindricks, Petr Neužil, Mayer Rashtian, Karel T N Breeman, Jordan R Nevo, Leonard Ganz, Chris Hubbard, Daniel J Cantillon
BACKGROUND: Single-chamber ventricular leadless pacemakers do not support atrial pacing or consistent atrioventricular synchrony. A dual-chamber leadless pacemaker system consisting of two devices implanted percutaneously, one in the right atrium and one in the right ventricle, would make leadless pacemaker therapy a treatment option for a wider range of indications. METHODS: We conducted a prospective, multicenter, single-group study to evaluate the safety and performance of a dual-chamber leadless pacemaker system...
May 20, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37212440/phase-1-trial-of-antibody-ni006-for-depletion-of-cardiac-transthyretin-amyloid
#7
JOURNAL ARTICLE
Pablo Garcia-Pavia, Fabian Aus dem Siepen, Erwan Donal, Olivier Lairez, Peter van der Meer, Arnt V Kristen, Michele F Mercuri, Aubin Michalon, Robert J A Frost, Jan Grimm, Roger M Nitsch, Christoph Hock, Peter C Kahr, Thibaud Damy
BACKGROUND: Transthyretin amyloid (ATTR) cardiomyopathy is a progressive and fatal disease caused by misfolded transthyretin. Despite advances in slowing disease progression, there is no available treatment that depletes ATTR from the heart for the amelioration of cardiac dysfunction. NI006 is a recombinant human anti-ATTR antibody that was developed for the removal of ATTR by phagocytic immune cells. METHODS: In this phase 1, double-blind trial, we randomly assigned (in a 2:1 ratio) 40 patients with wild-type or variant ATTR cardiomyopathy and chronic heart failure to receive intravenous infusions of either NI006 or placebo every 4 weeks for 4 months...
May 20, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37212438/enhancing-regulations-to-reduce-exposure-to-pfas-federal-action-on-forever-chemicals
#8
JOURNAL ARTICLE
Joseph M Braun
New England Journal of Medicine, Volume 388, Issue 21, Page 1924-1926, May 2023.
May 20, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37212435/public-health-s-role-in-a-post-dobbs-world-the-new-york-city-abortion-access-hub
#9
JOURNAL ARTICLE
Tara B Stein, Ashwin Vasan
New England Journal of Medicine, Volume 388, Issue 21, Page 1926-1929, May 2023.
May 20, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37212430/u-s-law-and-discrimination-in-health-care
#10
JOURNAL ARTICLE
Kimani Paul-Emile
New England Journal of Medicine, Volume 388, Issue 21, Page 1921-1924, May 2023.
May 20, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37212416/medication-related-osteonecrosis-of-the-jaw
#11
JOURNAL ARTICLE
Yu-Feng Chen, Hong-Po Chang
New England Journal of Medicine, Volume 388, Issue 21, May 2023.
May 20, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37199451/vaccine-effectiveness-of-jynneos-against-mpox-disease-in-the-united-states
#12
JOURNAL ARTICLE
Nicholas P Deputy, Joseph Deckert, Anna N Chard, Neil Sandberg, Danielle L Moulia, Eric Barkley, Alexandra F Dalton, Cory Sweet, Amanda C Cohn, David R Little, Adam L Cohen, Danessa Sandmann, Daniel C Payne, Jacqueline L Gerhart, Leora R Feldstein
BACKGROUND: In the United States, more than 30,000 cases of mpox (formerly known as monkeypox) had occurred as of March 1, 2023, in an outbreak disproportionately affecting transgender persons and gay, bisexual, and other men who have sex with men. In 2019, the JYNNEOS vaccine was approved for subcutaneous administration (0.5 ml per dose) to prevent mpox infection. On August 9, 2022, an emergency use authorization was issued for intradermal administration (0.1 ml per dose); however, real-world effectiveness data are limited for either route...
May 18, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37195934/mpox-among-linked-heterosexual-casual-partners-in-bayelsa-nigeria
#13
LETTER
Dimie Ogoina, Hendris I James
No abstract text is available yet for this article.
May 17, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37183985/advancing-community-living-for-people-with-disabilities
#14
JOURNAL ARTICLE
Ari Ne'eman, David C Grabowski
New England Journal of Medicine, Volume 388, Issue 20, Page 1825-1827, May 2023.
May 13, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37183984/the-thin-pane
#15
JOURNAL ARTICLE
Mark Earnest
New England Journal of Medicine, Volume 388, Issue 20, Page 1830-1831, May 2023.
May 13, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37183982/structural-ableism-essential-steps-for-abolishing-disability-injustice
#16
JOURNAL ARTICLE
Rupa Sheth Valdez, Bonnielin K Swenor
New England Journal of Medicine, Volume 388, Issue 20, Page 1827-1829, May 2023.
May 13, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37183981/primary-diffuse-meningeal-melanomatosis
#17
JOURNAL ARTICLE
Lei Wen, Linbo Cai
New England Journal of Medicine, Volume 388, Issue 20, Page 1892-1892, May 2023.
May 13, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37158447/randomized-trial-of-early-detection-and-treatment-of-postpartum-hemorrhage
#18
JOURNAL ARTICLE
Ioannis Gallos, Adam Devall, James Martin, Lee Middleton, Leanne Beeson, Hadiza Galadanci, Fadhlun Alwy Al-Beity, Zahida Qureshi, G Justus Hofmeyr, Neil Moran, Sue Fawcus, Lumaan Sheikh, George Gwako, Alfred Osoti, Ashraf Aswat, Kristie-Marie Mammoliti, Kulandaipalayam N Sindhu, Marcelina Podesek, Isobelle Horne, Rebecca Timms, Idnan Yunas, Jenipher Okore, Mandisa Singata-Madliki, Edna Arends, Aminu A Wakili, Ard Mwampashi, Sidrah Nausheen, Shah Muhammad, Pallavi Latthe, Cherrie Evans, Shahinoor Akter, Gillian Forbes, David Lissauer, Shireen Meher, Andrew Weeks, Andrew Shennan, Anne Ammerdorffer, Eleanor Williams, Tracy Roberts, Mariana Widmer, Olufemi T Oladapo, Fabiana Lorencatto, Meghan A Bohren, Suellen Miller, Fernando Althabe, Metin Gülmezoglu, Jeffrey M Smith, Karla Hemming, Arri Coomarasamy
BACKGROUND: Delays in the detection or treatment of postpartum hemorrhage can result in complications or death. A blood-collection drape can help provide objective, accurate, and early diagnosis of postpartum hemorrhage, and delayed or inconsistent use of effective interventions may be able to be addressed by a treatment bundle. METHODS: We conducted an international, cluster-randomized trial to assess a multicomponent clinical intervention for postpartum hemorrhage in patients having vaginal delivery...
May 9, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37158440/toward-comprehensive-care-for-long-covid
#19
JOURNAL ARTICLE
Janko Ž Nikolich, Clifford J Rosen
No abstract text is available yet for this article.
May 9, 2023: New England Journal of Medicine
https://read.qxmd.com/read/37155245/ethical-conflicts-for-clinicians-under-tennessee-abortion-law
#20
JOURNAL ARTICLE
Allison M McCarthy, Elise W Boos, Uchenna E Anani, Ellen W Clayton
New England Journal of Medicine, Volume 388, Issue 19, Page 1735-1737, May 2023.
May 6, 2023: New England Journal of Medicine
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