Clémence Ligneul, Chloé Najac, André Döring, Christian Beaulieu, Francesca Branzoli, William T Clarke, Cristina Cudalbu, Guglielmo Genovese, Saad Jbabdi, Ileana Jelescu, Dimitrios Karampinos, Roland Kreis, Henrik Lundell, Małgorzata Marjańska, Harald E Möller, Jessie Mosso, Eloïse Mougel, Stefan Posse, Stefan Ruschke, Kadir Simsek, Filip Szczepankiewicz, Assaf Tal, Chantal Tax, Georg Oeltzschner, Marco Palombo, Itamar Ronen, Julien Valette
Brain cell structure and function reflect neurodevelopment, plasticity, and aging; and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to noninvasively disentangle cellular structural features are needed and are a substantial focus of brain research. Diffusion-weighted MRS (dMRS) gives access to diffusion properties of endogenous intracellular brain metabolites that are preferentially located inside specific brain cell populations...
November 9, 2023: Magnetic Resonance in Medicine