journal
https://read.qxmd.com/read/38619399/liver-disease-etiology-and-race-ethnicity-are-associated-with-neighborhood-food-insecurity-risk-in-us-liver-transplant-candidates
#1
JOURNAL ARTICLE
Therese Bittermann, David S Goldberg, Rebecca K Rudel, Elena Byhoff
No abstract text is available yet for this article.
April 16, 2024: Liver Transplantation
https://read.qxmd.com/read/38619393/pursuing-living-donor-liver-transplantation-improves-outcomes-of-patients-with-autoimmune-liver-diseases-an-intention-to-treat-analysis
#2
JOURNAL ARTICLE
Owen Jones, Marco Paw Claasen, Tommy Ivanics, Woo Jin Choi, Felipe Gavaria, Luckshi Rajendran, Anand Ghanekar, Gideon Hirschfield, Aliya Gulamhusein, Chaya Shwaartz, Trevor Reichman, Blayne Amir Sayed, Markus Selzner, Mamatha Bhat, Cynthia Tsien, Elmar Jaeckel, Les Lilly, Ian D McGilvray, Mark S Cattral, Nazia Selzner, Gonzalo Sapisochin
Background Living donor liver transplantation (LDLT) offers the opportunity to decrease waitlist time and mortality for patients with AILD; autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC). We compared the survival of patients with a potential live donor (pLDLT) on the waitlist vs. no potential live donor (pDDLT), on an intention-to-treat (ITT) basis. Methods Our retrospective cohort study investigated adults with AILD listed for liver transplant at our program between 2000 and 2021...
April 16, 2024: Liver Transplantation
https://read.qxmd.com/read/38619390/efficiency-of-machine-perfusion-in-pediatric-liver-transplantation
#3
JOURNAL ARTICLE
Alessandro Parente, Mureo Kasahara, Vincent E De Meijer, Koji Hashimoto, Andrea Schlegel
Liver transplantation is the only lifesaving procedure for children with end-stage liver disease. The field is however heterogenic with various graft types, recipient age and weight and underlying diseases. Despite recently improved overall outcomes and the expanded use of living donors, waiting list mortality remains unacceptable particularly in small children and infants. Based on the known negative effect of elevated donor age, higher body mass index, and prolonged cold ischemia time, the number of available donors for pediatric recipients is limited...
April 16, 2024: Liver Transplantation
https://read.qxmd.com/read/38607654/allograft-involvement-with-post-transplant-lymphoproliferative-disorders-ptld-in-liver-transplant-recipients-a-clinicopathological-analysis-of-17-cases
#4
JOURNAL ARTICLE
Ruy J Cruz, Eizaburo Sasatomi, Christopher B Hughes, Abhinav Humar, Marta Minervini
No abstract text is available yet for this article.
April 12, 2024: Liver Transplantation
https://read.qxmd.com/read/38551399/introducing-the-new-controversies-in-liver-transplantation-corner
#5
JOURNAL ARTICLE
Marina Serper, Brett E Fortune, Andres Cardenas, Robert S Brown
No abstract text is available yet for this article.
April 1, 2024: Liver Transplantation
https://read.qxmd.com/read/38551397/recipient-hepatectomy-technique-may-affect-oncological-outcomes-of-liver-transplantation-for-hepatocellular-carcinoma
#6
JOURNAL ARTICLE
Riccardo Pravisani, Maria De Martino, Federico Mocchegiani, Fabio Melandro, Damiano Patrono, Andrea Lauterio, Fabrizio Di Francesco, Matteo Ravaioli, Marco Fabrizio Zambelli, Claudio Bosio, Daniele Dondossola, Quirino Lai, Matteo Zanchetta, Jule Dingfelder, Luca Toti, Alessandro Iacomino, Sermed Nicolae, Davide Ghinolfi, Renato Romagnoli, Luciano De Carlis, Salvatore Gruttadauria, Matteo Cescon, Michele Colledan, Amedeo Carraro, Lucio Caccamo, Marco Vivarelli, Massimo Rossi, Silvio Nadalin, Georg Gyori, Giuseppe Tisone, Giovanni Vennarecci, Andreas Rostved, Paolo De Simone, Miriam Isola, Umberto Baccarani
BACKGROUND: To date, caval sparing (CS) and total caval replacement (TCR) for recipient hepatectomy in liver transplantation (LT) have been compared only in terms of surgical morbidity. Nonetheless, CS technique is inherently associated with an increased manipulation of the native liver and later exclusion of the venous outflow, which may increase the risk of intraoperative shedding of tumor cells when LT is performed for hepatocellular carcinoma (HCC). METHODS: A multicenter, retrospective study was performed to assess the impact of recipient hepatectomy (CS vs...
April 1, 2024: Liver Transplantation
https://read.qxmd.com/read/38551388/bariatric-surgery-post-liver-transplantation-a-belgian-nationwide-study
#7
JOURNAL ARTICLE
Louis Onghena, Anja Geerts, Frederik Berrevoet, Jacques Pirenne, Jef Verbeek, Eliano Bonaccorsi-Riani, Geraldine Dahlqvist, Luisa Vonghia, Olivier Detry, Jean Delwaide, Sander Lefere, Yves van Nieuwenhove
BACKGROUND: Weight gain poses a rising concern post-liver transplantation (LT), and metabolic dysfunction-associated steatotic liver disease (MASLD) might impair graft health. The timing is crucial when considering bariatric surgery (BS) in a population with liver disease or transplantation. BS can be considered for post-LT weight gain, although the evidence is limited and the long-term outcome still uncertain. METHODS: We conducted a national retrospective analysis in 5 Belgian transplant centres and included 25 patients with a liver transplantation followed by a bariatric procedure...
April 1, 2024: Liver Transplantation
https://read.qxmd.com/read/38537069/controversies-in-terlipressin-and-transplantation-in-the-united-states-how-do-we-meld-the-two
#8
JOURNAL ARTICLE
Eric M Przybyszewski, Robert M Wilechansky, Paige McLean Diaz, Andrew S Allegretti, Lisa B VanWagner, Giuseppe Cullaro, Josh Levitsky, Pere Ginès, Salvatore Piano, Sumeet K Asrani, Kavish R Patidar
Hepatorenal syndrome-acute kidney injury (HRS-AKI) is a severe complication of cirrhosis that carries a poor prognosis. The recent Food and Drug Administration approval of terlipressin has substantial implications for managing HRS-AKI and liver allocation in the United States (US). Terlipressin has been available in Europe for over a decade, and several countries have adapted policy changes such as Model for End-Stage Liver Disease (MELD) score "lock" for HRS-AKI. In this article, we outline the European experience with terlipressin use and explore the question of whether terlipressin treatment for HRS-AKI should qualify for MELD score "lock" in the US in those who respond to therapy...
March 28, 2024: Liver Transplantation
https://read.qxmd.com/read/38535627/sleep-disturbances-in-chronic-liver-disease
#9
JOURNAL ARTICLE
Bradley Busebee, Kymberly D Watt, Kara Dupuy-McCauley, Hilary DuBrock
Sleep disturbances are common in chronic liver disease and significantly impact patient outcomes and quality of life. The severity and nature of sleep disturbances vary by liver disease etiology and severity. While there is ongoing research into the association between liver disease and sleep-wake dysfunction, the underlying pathophysiology varies and, in many cases, is poorly understood. Liver disease is associated with alterations in thermoregulation, inflammation, and physical activity, and is associated with disease specific complications, such as hepatic encephalopathy, that may directly affect sleep...
March 27, 2024: Liver Transplantation
https://read.qxmd.com/read/38535617/identifying-drivers-of-cost-in-pediatric-liver-transplantation
#10
JOURNAL ARTICLE
Divya Sabapathy, Kathleen Hosek, Fong W Lam, Moreshwar S Desai, Eric Williams, John Goss, Jean L Raphael, Michelle A Lopez
BACKGROUND & AIMS: Understanding the economics of pediatric liver transplantation (LT) is central to high-value care initiatives. We examined cost and resource utilization in pediatric LT nationally to identify drivers of cost and hospital factors associated with greater total cost of care. APPROACH & RESULTS: We reviewed 3295 children (<21 y) receiving a LT from 2010-2020 in the Pediatric Health Information System to study cost, both per LT and service-line, and associated mortality, complications and resource utilization...
March 27, 2024: Liver Transplantation
https://read.qxmd.com/read/38535524/coronary-ct-angiography-for-predicting-early-post-liver-transplant-mace-paradigm-shift-or-part-of-the-calculus
#11
JOURNAL ARTICLE
Brian Hughes, Michael Kriss, Jon Rice
No abstract text is available yet for this article.
March 27, 2024: Liver Transplantation
https://read.qxmd.com/read/38535488/outpatient-mean-arterial-pressure-a-potentially-modifiable-risk-for-acute-kidney-injury-and-death-among-cirrhosis-patients
#12
JOURNAL ARTICLE
Giuseppe Cullaro, Sy Han Chiou, Cynthia Fenton, Jin Ge, Charles E McCulloch, Jessica Rubin, Amy M Shui, Frederick Yao, Jennifer C Lai
BACKGROUND: Mean arterial blood pressure (MAP), which decreases as portal hypertension progresses, may be a modifiable risk factor among cirrhosis patients. METHODS: We included adults enrolled in the FrAILT study. We completed latent class trajectory analyses (LCTA) to define MAP trajectories. We completed time-dependent Cox-regression analyses to test the association between outpatient MAP and 3 cirrhosis-related outcomes: 1) Stage 2 acute kidney injury (AKI), defined as a ≥200% increase in serum creatinine from baseline; 2) a 5-point increase in the MELDNa score, defined as the incidence of increase from initial MELDNa; 3) waitlist mortality (WLM), defined as death on the WL...
March 27, 2024: Liver Transplantation
https://read.qxmd.com/read/38497790/breathing-new-life-to-posttransplant-survival-models
#13
JOURNAL ARTICLE
Avegail Flores, Ruben Hernaez
No abstract text is available yet for this article.
March 19, 2024: Liver Transplantation
https://read.qxmd.com/read/38497771/can-semaglutide-result-in-a-tangible-cardiovascular-benefit-in-liver-transplant-recipients
#14
JOURNAL ARTICLE
Bruno Sensi, Tommaso Maria Manzia
No abstract text is available yet for this article.
March 19, 2024: Liver Transplantation
https://read.qxmd.com/read/38497743/reply-coronary-ct-angiography-for-predicting-early-post-liver-transplant-mace-paradigm-shift-or-part-of-the-calculus
#15
JOURNAL ARTICLE
Thalys Sampaio Rodrigues, Anoop N Koshy, Benjamin Cailes, Avik Majumdar, Omar Farouque
No abstract text is available yet for this article.
March 19, 2024: Liver Transplantation
https://read.qxmd.com/read/38483195/testing-democracy-in-transplant
#16
JOURNAL ARTICLE
Elora Basu, Akhil Shenoy, Mashal Khan
No abstract text is available yet for this article.
March 15, 2024: Liver Transplantation
https://read.qxmd.com/read/38471011/-prediction-is-very-difficult-especially-if-it-s-about-the-future
#17
JOURNAL ARTICLE
Whitney E Jackson, Bruce Kaplan
No abstract text is available yet for this article.
March 13, 2024: Liver Transplantation
https://read.qxmd.com/read/38471008/management-of-alcohol-associated-liver-disease-and-alcohol-use-disorder-in-liver-transplant-candidates-and-recipients-challenges-and-opportunities
#18
JOURNAL ARTICLE
Pratima Sharma, Akhil Shenoy, Hersh Shroff, Allison Kwong, Nicholas Lim, Anjana Pillai, Deepika Devuni, Lamia Y Haque, Wendy Balliet, Marina Serper
Alcohol-associated liver disease (ALD) poses a significant global health burden, with rising alcohol consumption and prevalence of alcohol use disorder (AUD) contributing to increased morbidity and mortality. This review examines the challenges and opportunities in the care of liver transplant (LT) candidates and recipients with AUD. Despite advancements in post-transplant patient survival, the risk of disease recurrence and alcohol relapse remains substantial. Several challenges have been identified, including (1) rising disease burden of ALD, variable transplant practices, and systemic barriers; (2) disparities in mental health therapy access and the impact on transplant; (3) variable definitions, underdiagnosis, and stigma affecting access to care; and (4) post-LT relapse, its risk factors, and consequential harm...
March 13, 2024: Liver Transplantation
https://read.qxmd.com/read/38471005/association-of-chronic-liver-disease-mortality-and-patient-travel-time
#19
JOURNAL ARTICLE
Neelima Gaddipati, Darius Chyou, Catherine Blandon, David S Goldberg
No abstract text is available yet for this article.
March 13, 2024: Liver Transplantation
https://read.qxmd.com/read/38466888/policy-corner-what-s-my-meld-score-mmat-3
#20
JOURNAL ARTICLE
Craig Rosenstengle, James Trotter, Shivang Mehta
No abstract text is available yet for this article.
March 11, 2024: Liver Transplantation
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