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Evan J Patel, Meleha Ahmad, Brian S Schwartz, Annemieke van Zante, Robert Kersten, Patricia Loftus
Acute invasive fungal sinusitis (AIFS) classically presents as an aggressive fungal infection that can spread beyond its origin in the sinuses in immunocompromised patients. Although there have been reports of AIFS in immunocompetent, non-diabetic patients, it is extremely rare and the true mechanism behind it is unknown. A thirty-eight year old immunocompetent, non-diabetic woman underwent bilateral ESS for chronic rhinosinusitis with nasal polyps at a tertiary care center and post-operatively developed AIFS...
April 23, 2024: Laryngoscope
#2
JOURNAL ARTICLE
Sabri El-Saied, Amit Amar, Daniel M Kaplan, Rivka Shitrit, Benyamin M Kaminer, Aharon Keshet, Eli C Lewis
BACKGROUND: Most tympanic membrane (TM) perforations heal spontaneously, but 10%-20% remain chronic and might lead to impaired hearing and recurrent middle ear infections. Alpha1-antitrypsin (AAT) is a circulating tissue-protective protein that is elevated under inflammatory conditions and is currently indicated for genetic AAT deficiency. Recently, AAT has been shown to promote tissue remodeling and inflammatory resolution. OBJECTIVE: This study aimed to examine the effects of local clinical-grade AAT treatment on tissue repair in a mouse model of acute traumatic TM perforation...
April 23, 2024: Laryngoscope
#3
JOURNAL ARTICLE
Amirpouyan Namavarian, Alexander Gabinet-Equihua, Yangqing Deng, Shuja Khalid, Hedyeh Ziai, Konrado Deutsch, Jingyue Huang, Ralph W Gilbert, David P Goldstein, Christopher M K L Yao, Jonathan C Irish, Danny J Enepekides, Kevin M Higgins, Frank Rudzicz, Antoine Eskander, Wei Xu, John R de Almeida
OBJECTIVE: Accurate prediction of hospital length of stay (LOS) following surgical management of oral cavity cancer (OCC) may be associated with improved patient counseling, hospital resource utilization and cost. The objective of this study was to compare the performance of statistical models, a machine learning (ML) model, and The American College of Surgeons National Surgical Quality Improvement Program's (ACS-NSQIP) calculator in predicting LOS following surgery for OCC. MATERIALS AND METHODS: A retrospective multicenter database study was performed at two major academic head and neck cancer centers...
April 23, 2024: Laryngoscope
#4
Tice R Harkins, Vasiliki Triantafillou, Everett Seay, Alan R Schwartz, Raj C Dedhia
A 47-year-old male patient diagnosed with severe obstructive sleep apnea (OSA) sought alternatives to positive airway pressure, prompting evaluation with drug-induced sleep endoscopy (DISE). He underwent a specialized DISE with nasal airflow and pharyngeal pressure monitoring. During obstructive apneas, airflow and pressure signals demonstrated dynamic, multilevel upper airway collapse, with shifting sites of airflow obstruction as respiratory effort increased. This case report illustrates how quantitative airflow and pressure measurements can complement the standard DISE exam and aid in surgical decision-making...
April 23, 2024: Laryngoscope
#5
JOURNAL ARTICLE
Ashley Young, Krupa Patel, Kiona Allen, Saied Ghadersohi, Matthew Rowland, Inbal Hazkani
BACKGROUND: We aim to describe our experience with bronchoscopy to diagnose and relieve tracheobronchial obstruction in anticipation of decannulation in children on extracorporeal membrane oxygenation (ECMO) support. METHODS: A retrospective cohort study of children on ECMO between 1/2018 and 12/2022. RESULTS: A total of 107 children required ECMO support during the study period for cardiac (n = 48, 45%), pulmonary (n = 38, 36%), or cardiopulmonary dysfunction (n = 21, 20%)...
April 23, 2024: Laryngoscope
#6
JOURNAL ARTICLE
Amiti Jain, Zachary N Goldberg, Erin Briggs, Dev R Amin, Zachary D Urdang, Richard A Goldman, David M Cognetti, Joseph M Curry
OBJECTIVE: The modified frailty index (mFI-5) is a National Surgical Quality Improvement Program-derived 5-factor index that has been proven to reflect frailty and predict morbidity and mortality. We hypothesize that mFI-5 is a valid predictive measure in the transoral robotic surgery (TORS) population. METHODS: Retrospective study utilizing the TriNetX US-collaborative health records network querying for TORS patients. Cohorts were stratified by mFI-5 score which uses five ICD-10 codes: nonindependent functional status, hypertension, obstructive respiratory disease, heart failure, and diabetes mellitus...
April 23, 2024: Laryngoscope
#7
REVIEW
Mohammad Bilal Alsavaf, Moataz D Abouammo, Govind S Bhuskute, Shuai Sun, Majd Issa, Nolan B Seim, Kyle K VanKoevering, Priyanka Bhateja, Marcelo Bonomi, Ricardo L Carrau
OBJECTIVE: To comprehensively analyze reported cases of nasolacrimal squamous cell carcinoma (NLSCC), focusing on risk factors, treatment modalities, and outcomes. Additionally, investigate the impact of human Papillomavirus (HPV) status and histopathological subtypes' impact on prognosis. DATA SOURCES: Pubmed, Embase. REVIEW METHODS: We conducted a systematic literature review to identify relevant studies reporting cases of NLSCC. The review methods adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines...
April 23, 2024: Laryngoscope
#8
Leonardo Franz, Ingrid Inches, Salvatore Fermo, Alessandro Matarazzo, Cosimo de Filippis, Gino Marioni
Pneumo-membranous labyrinth is an almost unique condition, in which air extends into the membranous labyrinth, filling the endolymphatic sac through the vestibular aqueduct. In this manuscript, we describe and discuss a case of pneumo-membranous labyrinth, with air bubbles extending also to the endolymphatic sac, resulting in anacusis, following hyperbaric oxygen therapy for sudden sensorineural hearing loss. The patient was successfully rehabilitated with a cochlear implant, obtaining a pure-tone average of 30 dB, with a speech discrimination score of 100% at 70 dB...
April 22, 2024: Laryngoscope
#9
JOURNAL ARTICLE
Jessa E Miller, Eugene Oh, Aastha Khatiwada, Stephen M Humphries, Alexandra Wilson, Eszter K Vladar, David A Lynch, Jennifer L Taylor-Cousar, Daniel M Beswick
No abstract text is available yet for this article.
April 22, 2024: Laryngoscope
#10
JOURNAL ARTICLE
Daniel M Beswick, Christine M Liu, Jonathan B Overdevest, Anna Zemke, Aastha Khatiwada, David A Gudis, Jessa E Miller, Adam Kimple, Jeremy P Tervo, Emily DiMango, Jennifer L Goralski, Claire Keating, Brent Senior, Amanda L Stapleton, Patricia H Eshaghian, Jess C Mace, Karolin Markarian, Jeremiah A Alt, Todd E Bodner, Naweed I Chowdhury, Anne E Getz, Peter H Hwang, Ashoke Khanwalker, Jivianne T Lee, Douglas A Li, Meghan Norris, Jayakar V Nayak, Cameran Owens, Zara M Patel, Katie Poch, Rodney J Schlosser, Kristine A Smith, Timothy L Smith, Zachary M Soler, Jeffrey D Suh, Grant A Turner, Marilene B Wang, Milene T Saavedra, Jennifer L Taylor Cousar
OBJECTIVES: The 22-question SinoNasal Outcome Test (SNOT-22) assesses chronic rhinosinusitis (CRS) severity. We aimed to identify predictors of SNOT-22 score improvement following highly effective modulator therapy (HEMT) initiation and to corroborate the SNOT-22 minimal clinically important difference (MCID) in adults with cystic fibrosis (CF). METHODS: Prospective observational data was pooled from four studies across 10 US centers investigating people with CF (PwCF) and CRS...
April 18, 2024: Laryngoscope
#11
Youssef Lakhdar, Salah-Eddine Youbi, Omar Oulghoul, Mohammed Chehbouni, Othmane Benhoummad, Youssef Rochdi, Abdelaziz Raji
The petrosquamosal sinus is a rare and almost unknown emissary vein of the temporal bone. It traverses the middle cranial fossa along the petrosquamosal fissure and connects dural sinuses with extracranial venous networks. It is known to undergo normal involution during fetal and early postnatal life, and therefore is rarely found in humans. When encountered during surgery, it can be a significant source of bleeding hindering proper visualization of important surgical landmarks. Here we report the case of a PSS, encountered in a child during cochlear implantation surgery...
April 16, 2024: Laryngoscope
#12
JOURNAL ARTICLE
Wenwei Luo, Xiao Fu, Hongming Huang, Peina Wu, Yanmei Wang, Zhifeng Liu, Shiqi He, Limin Pang, Dongdong Ren, Yong Cui
OBJECTIVES: Planar cell polarity (PCP) signaling, essential for uniform alignment and directional beating of motile cilia, has been investigated in multiciliated epithelia. As a complex structure connecting the middle ear to the nasopharynx, the eustachian tube (ET) is important in the onset of ear-nose-throat diseases. However, PCP signaling, including the orientation that is important for ciliary motility and clearance function in the ET, has not been studied. We evaluated PCP in the ET epithelium...
April 13, 2024: Laryngoscope
#13
REVIEW
Zahir Mughal, Keshav Kumar Gupta, Justin Jui Yuan Yeo, Christopher Metcalfe, Matthew Weller
OBJECTIVE: Abscess tonsillectomy is performed during an active episode of quinsy. Apprehensions regarding an elevated bleeding risk have hindered its widespread acceptance. This study aims to assess the prevalence of post-tonsillectomy bleeding (PTB) associated with abscess tonsillectomy. DATA SOURCES: A search was performed on August 27, 2023 in Medline, Embase, PubMed, Cochrane CENTRAL, and Web of Science databases. REVIEW METHODS: The systematic review was conducted in adherence to the PRISMA guidelines...
April 13, 2024: Laryngoscope
#14
Evan J Propst, Jennifer M Siu, Nikolaus E Wolter
A 15-year-old male with previous open tracheoesophageal fistula (TEF) repair presented with a large, short recurrent TEF. The TEF was denuded with cautery on the tracheal side and the patient was intubated with a cuffed endotracheal tube. Suspension microesophagoscopy allowed excellent exposure of the TEF from the esophageal side, which was cauterized. Four sutures were placed endoscopically from the esophageal side, and the TEF remained closed 6 months postoperatively. Laryngoscope, 2024.
April 13, 2024: Laryngoscope
#15
JOURNAL ARTICLE
Carolyn A Wilson, Taylor L Jamil, Preetha S Velu, Jessica R Levi
OBJECTIVE: To determine if patient factors related to ethnicity, socioeconomic status (SES), medical comorbidities, or appointment characteristics increase the risk of missing an initial adult otolaryngology appointment. METHODS: This study is a retrospective case control study at Boston Medical Center (BMC) in Boston, Massachusetts, that took place in 2019. Patient demographic and medical comorbidity data as well as appointment characteristic data were collected and compared between those that attended their initial otolaryngology appointment versus those who missed their initial appointment...
April 11, 2024: Laryngoscope
#16
JOURNAL ARTICLE
Vikram Vasan, Christopher P Cheng, David K Lerner, Karen Pascual, Amanda Mercado, Alfred Marc Iloreta, Marita S Teng
INTRODUCTION: Letters of recommendation (LORs) are a highly influential yet subjective and often enigmatic aspect of the residency application process. This study hypothesizes that LORs do contain valuable insights into applicants and can be used to predict outcomes. This pilot study utilizes natural language processing and machine learning (ML) models using LOR text to predict interview invitations for otolaryngology residency applicants. METHODS: A total of 1642 LORs from the 2022-2023 application cycle were retrospectively retrieved from a single institution...
April 11, 2024: Laryngoscope
#17
JOURNAL ARTICLE
Michael J Warn, Sina J Torabi, Benjamin F Bitner, Daniella Chan, Theodore V Nguyen, Edward C Kuan
INTRODUCTION: Current data regarding reimbursement trends in Medicare services and the complexity of patients treated as physicians' progress in their academic career are conflicting. In otolaryngology, there are no data examining these metrics. METHODS: Medicare services, reimbursement, and patient complexity risk scores (based on hierarchical condition category coding) of US rhinology fellowship-trained faculty were stratified and compared by rank and years in practice...
April 10, 2024: Laryngoscope
#18
JOURNAL ARTICLE
Constantin A Hintschich, Cindy Ma, Antje Hähner, Thomas Hummel
OBJECTIVES: Olfactory habituation is a transient decrease in olfactory sensitivity caused by prolonged odor exposure, aiding in the discernment of new olfactory stimuli against the background. We explored the impact of subclinical olfactory impairment on odor habituation using age as a proxy. METHODS: Before the actual experiment, the individual olfactory threshold for the rose-like odorant phenylethyl alcohol (PEA) was assessed separately for the left and right nostril using the "Sniffin' Sticks" test, and ratings for odor intensity and pleasantness were collected...
April 10, 2024: Laryngoscope
#19
JOURNAL ARTICLE
Büşra Kaplan, Büşra Altın, Mehmet Umut Akyol, Songül Aksoy
BACKGROUND: Otitis media with effusion (OME) frequently leads to vestibular symptoms in children. However, young children face difficulty expressing their symptoms due to their limited language abilities. METHODS: The balance of study and patient group evaluated with computer dynamic posturography, single-leg stance test with eyes closed and regular Head Impulse Test. The study group was assessed once again after the insertion of a ventilation tube two months later...
April 10, 2024: Laryngoscope
#20
JOURNAL ARTICLE
Makoto Hosoya, Shuta Tomisato, Nobuharu Matsumoto, Haruna Yabe, Takuji Takaoka, Hiroyuki Ozawa, Takeyuki Kono
OBJECTIVE: Pemphigus Vulgaris (PV) is a rare autoimmune disease that could cause laryngeal lesions; however, only a few studies have described the localization of the laryngeal lesions associated with this disease owing to its rarity. Therefore, this study aimed to determine the localization of laryngeal lesions in patients with PV. METHODS: Fourteen patients with PV accompanied by laryngeal or pharyngeal lesions, who underwent flexible laryngeal endoscopy performed by laryngologists, were examined retrospectively...
April 10, 2024: Laryngoscope
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